• 제목/요약/키워드: 14 S-N Method

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Effects of EA Application to GV20 and LI4 on BAX and NF-kB Expression of the SD-Rat's Hippocampus with Global Ischemia

  • Choi, Jung-Hyun;Kim, Sung-Won;Lee, Jae-Gap;Kim, Min-Hee;Kim, Ji-Sung;Choi, Yoo-Rim;Yun, Young-Dae;Kim, Chi-Hyok;Kim, Yong-Seong;Kim, Nyeon-Jun;Lee, Ju-Hwan;Lee, Sang-Bin
    • 국제물리치료학회지
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    • 제1권2호
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    • pp.136-142
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    • 2010
  • This study aims to reveal how EA affects BAX and NF-kB involved in cell deaths from global ischemia, and to do this, observes the changes of BAX and NF-kB caused by EA application after transient global ischemia. The experimental method is to give rise to global ischemia and apply EA to 27 SD rats with the particulars of being six-week-old, male, around-300 gram-weighing, and adapted to laboratory environment for more than a week, and divide them into three groups, that is, GV20 EA group(n=9), L14 EA group(n=9), no-treatment GI group(n=9), and then observe their changes of BAX and NF-kB at the time lapse of 6 hours, 9 hours and 12 hours after ischemia, using western blotting. The numerical decrease of BAX expression at the time lapse of 9 hours after EA application, though not statistically significant, was observed in GV20 EA group and L14 EA group, and the NF-kB expression appeared statistically significant decrease in GV20 EA group and L14 EA group, but the expression was higher in the group with EA application. Therefore, EA application at the early phase of global ischemia is considered to affect BAX and NF-kB and play a positive role in decreasing apoptosis and cell deaths by inflammation.

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The Structure of 1-[2-[[(4-chlorophenyl)-methyl]thio]-2-(2, 4-dichlorphenyl)ethyl]-1H imidazole (Sulconazole) nitrate, C18H16Cl3N3O3S

  • Shin, Hyun-So;Song, Hyun;Cho, Sung-Il;Pakr, Keun-Il
    • Bulletin of the Korean Chemical Society
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    • 제18권1호
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    • pp.14-18
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    • 1997
  • Sulconazole nitrate, C18H16Cl3N3O3S, crystallizes in monoclinic, space group C2/c, with a=14.401(1), b=8.051(1), c=34.861(2) Å, β=95.9(1)°, g=0.58 mm-1, Dc=1.523 g/cm3, Dm=1.522 g/cm3, F(000)=1888.0, and z=8. Intensities for 2460 unique reflections were measured on a CAD4 diffractometer with graphited-monochromated Mo-Kα radiation. The structure was solved by direct method and refined by full matrix least squares to a final R=0.071 for 2182 reflections (Io > 2σIo). The bond lengths and angles are comparable with the values found in the analogues imidazole derivatives. The 2,4-dichlorophenyl ring(A) and the p-chlorophenyl ring(B) are almost planar with different heights [dihedral angle 17.3°] while the imidazole ring(C) is nearly perpendicular to the two phenyl rings[dihedral angles about the two rings A, B are 110.8° and 96.1° respectively]. In order to understand the overall conformation we calculated the selected distances (l1, l2, l3) among the center of the three rings and considered the imaginary plan D[C(7), C(9) and C(16)]. The two polar group S(8) and N(19) do not have gauche conformation and l2 value (4.47 Å) is shorter than the other imidazole derivatives. One -NO3 group are hydrogen bonded the two neighbored sulconazole molecules. The molecular crystal packing is also formed by two hydrogen bondings and van der Waals forces.

최대 선호도 순위선정 방법에 기반한 결혼문제 알고리즘 (Marriage Problem Algorithm Based on Maximum-Preferred Rank Selection Method)

  • 이상운
    • 한국인터넷방송통신학회논문지
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    • 제14권3호
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    • pp.111-117
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    • 2014
  • 본 논문은 안정된 결혼문제의 최적 해를 쉽고 빠르게 찾는 알고리즘을 제안하였다. 첫 번째로, 남성의 여성선호도와 여성의 남성 선호도 합 $p_{ij}$$n{\times}n$ 정방행렬 할당문제로 변환시킨다. 두 번째로, 행렬에서 최대 선호도 합(최소 값)인 $_{min}p_{ij}$를 선택하고 i행과 j열을 삭제한다. 이 과정을 $i=0{\cap}j=0$일 때까지 수행한다. 세 번째로, 가능한 최초 또는 마지막 선택 $_{min}p_{ij}$에 대해 다른 값으로 변경시 선호도를 증가시킬 수 있으면 상호 교환하는 검증 절차를 수행한다. 제안된 알고리즘을 7개의 안정된 결혼문제에 적용한 결과 기존 알고리즘의 해를 개선하는 효과를 얻었다.

이면전계(BSF)에의한 solar cell의 효율개선효과 (Efficiency improvement of solar cell by back surface field)

  • 소대화;강기성;박정철
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1990년도 추계학술대회 논문집
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    • pp.88-90
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    • 1990
  • In this study, PN junction solar cell and P$\^$+/-N-N$\^$+/ BSF solar cell, using N-type(111), 10$\^$16/[atoms/cm$\^$-3/] wafer, were fabricated applying that ion implant method whose dose are 1E14, 1E15, 3E15 and its acceleration energy is 50Key, 100Key respectively. The impurity concentration of two types of front-side are 10$\^$18/[atoms/cm$\^$-3/] and back-side concentration for BSF solar cell is 10$\^$17/[atoms/cm$\^$-3/]. As a result of comparison for 2 typical types of cells out of various fabricated samples, open circuit voltage (Voc), short circuit current(Isc) of BSF solar cell are larger than those of PN solar cell by 48[%], 14[%]. Considering that the efficiency of BSF cell is 2.5[%] as well as PN solar cell's is 7.5[%], 10.0[%] of efficiency improvement effect can be obtained from BSF solar cell. Futhermore, in consequence of front-side impurity concentration change from 10$\^$17/[atoms/cm$\^$-3] to 10$\^$20/[atoms/cm$\^$-3/] alternately, the most ideal result can be expected when it is 10$\^$18/[atoms/cm$\^$-3/].

Short- and long-term deflections of RC building structures influenced by construction processes

  • Alvarado, Yezid A.;Buitrago, Manuel;Gasch, Isabel;Dominguez, Maria N.;Cipagauta, Miguel A.
    • Structural Engineering and Mechanics
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    • 제64권2호
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    • pp.173-181
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    • 2017
  • This paper analyzes the influence of the construction process on short- and long-term deflections on a reinforced concrete structure poured on-site by a portable industrialized system. A parametric analysis was carried out by the Finite Elements Method (FEM) that considered: a) type of construction process with reshoring or clearing (partial striking); b) the number of successively shored floors and c) the number of shores used on each floor. All three factors were especially important for the values of short- and long-term deflections, which were highest in the reshoring processes with the lowest number of successively shored floors and the lowest number of shores per floor. Deflections obtained were compared with the limits laid down by ACI 318-14 and as calculated by this code's simplified method. The long-term deflections were seen to be almost double than those obtained by applying the ACI 318-14 code's simplified method and in some cases these deflections were above the established limits. It can thus be concluded that the load history of a building under construction should be taken into account in order to satisfy a structure's in-service conditions and durability.

파괴시험 계수형 샘플링검사 경제적 시료 크기 결정에 관한 연구 (A Study on the Determination of the Economic Sample Size of the Attribute Acceptance Sampling Plans for Destructive Testing)

  • 김병재
    • 산업경영시스템학회지
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    • 제4권5호
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    • pp.11-14
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    • 1981
  • This study intends to decide the economic sample size based on the cost of sampling Inspection for destructive testing. The marginal percent defective is used as the lot tolerance percent defective (LTPD), and the Newton's iterative method is adopted to calculate the optimum sample size(n), given by the consumer's risk($\beta$ - risk) and the acceptance number(c).

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가스크로마토그라피/질량분석기에 의한 모발중 대마성분 분석 (Analysis of $\triangle^9$-Tetrahydrocannabinol and 11-nor-9-carboxytetrahydrocannabinol in Hair by Gas Chromatography/Mass Spectrometry)

  • 양원경;한은영;박용훈;임미애;정희선
    • 약학회지
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    • 제48권3호
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    • pp.207-212
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    • 2004
  • An analytic method was developed for the quantitation of $\Delta$$^{9}-$ tetrahydrocannabinol (THC) and 11-nor-9-carboxy THC (THC-COOH) in human hair. After hair samples were pulverized using Freezer Mill, deuterated internal standards were added and digested in 1 N NaOH at $100^{\circ}C$ water bath for 30 min. Digest solutions were extracted by 5 ml hexane:ethyl acetate (90:10) after acidification with acetic acid. The organic phase was evaporated under N 2 and derivatized by BSTFA (with 1% TMCS) at $85^{\circ}C$ for 45 min. The derivatized solution was separated on HP-5MS column ($30m{\times}0.25mm{\times}0.25mm$) and detected using EI-GC-MS with selective ion monitoring mode. The assay of calibration was ranged from 5 to 100 ng/50 mg hair ($r^2$>0.99) for THC and THC-COOH. Within and between-run precision were calculated at 6, 30, 60 ng/50 mg hair with coefficients of variation less than 11%. Within and between run accuracies at the same concentrations were$\pm$14% and $\pm$30% of target for both analytes, respectively. Absolute and relative recovery at 10 and 100 ng were 60∼91%. The method was used to detect and quantify THC and THC-COOH in cannabis abuser's hairs (N = 16) and SRM (N=5, THC 1 ng/mg, NIST). We detected THC and THC-COOH in only one hair sample. In SRM, % accuracy was 93% (range 86∼103%) and precision (% CV) was 8.14. We began to set up a quantitative analysis of THC and THC-COOH using EI-GC-MS. Continuously, we need to modify and develop this method in order to apply for identification in cannanbis users' hair.

Thermal Degradation Kinetics of Antimicrobial Agent, Poly(hexamethylene guanidine) Phosphate

  • Lee, Sang-Mook;Jin, Byung-Suk;Lee, Jae-Wook
    • Macromolecular Research
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    • 제14권5호
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    • pp.491-498
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    • 2006
  • The thermal degradation of poly(hexamethylene guanidine) phosphate (PHMG) was studied by dynamic thermogravimetric analysis (TGA) and pyrolysis-GC/MS (p-GC). Thermal degradation of PHMG occurs in three different processes, such as dephosphorylation, sublimation/vaporization of amine compounds and decomposition/ recombination of hydrocarbon residues. The kinetic parameters of each stage were calculated from the Kissinger, Friedman and Flynn-Wall-Ozawa methods. The Chang method was also used for comparison study. To investigate the degradation mechanisms of the three different stages, the Coats-Redfern and the Phadnis-Deshpande methods were employed. The probable degradation mechanism for the first stage was a nucleation and growth mechanism, $A_n$ type. However, a power law and a diffusion mechanism, $D_n$ type, were operated for the second degradation stage, whereas a nucleation and growth mechanism, $A_n$ type, were operated again for the third degradation stage of PHMG. The theoretical weight loss against temperature curves, calculated by the estimated kinetic parameters, well fit the experimental data, thereby confirming the validity of the analysis method used in this work. The life-time predicted from the kinetic equation is a valuable guide for the thermal processing of PHMG.

Isoproterenol이 백서구강점막의 비만세포에 미치는 영향 (Effects of Isoproterenol on the Mast Cells in The Oral Mucosa of Albino Rats.)

  • 고재승;송완영
    • 대한치과의사협회지
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    • 제11권6호
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    • pp.383-386
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    • 1973
  • The effects of isoproterenol, a sympathomimetic amine, on the mast cells in the oral mucosa were cytochemically studied in twenty four healthy male albino rats weighing approximately 100gm. seven groups of three each were injected intraperitoneally, as a single dose of 8mg/100gm. body wt., (dissolved in 0.9% saline 0.2㎖). Each groups were sacrificed following ether anesthesia at he time indicated, 1. 2. 3. 5. 7. 10. 14days after only a single injection. One normal group is not administered with any substances. The sections of oral mucosa were stained with 0.005% toluidine blue (Mowry's method) and alcian blue (pH 2.5). We found that isoproterenol made an initial decrease in the metachromasia and alcian blue affinity, and the number of mast cell, followed by an subsequent return to normal.

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