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Changes in Blood Lipid Profile and Hepatic Enzyme Levels after Oriental Medical Treatment to Metabolic Syndrome Patients with Abnormal Liver Function

  • Kim, Dong-Woung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.6
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    • pp.1626-1632
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    • 2008
  • Among patients who are receiving treatments at an oriental medical hospital for various symptoms and diseases, patients whose main disease is accompanied by metabolic syndrome with abnormal liver function. This research was performed in order to observe the progression of changes in the liver function and serum lipid profile after the oriental medical treatments to patients who have been receiving oriental medical treatment for various other diseases and have been diagnosed as having metabolic syndrome at their first visit to the hospital based on NCEP ATP III diagnosis criteria and WHO Asia Pacific region criteria. Total number of subject patients were 39cases(mean age:55.58${\pm}$2.09 years) which had 20 male and 19 female. For the references for hepatic enzyme levels and blood lipid profile were measured in before treatment and four times after treatments(every 2.31${\pm}$06.17 weeks). Serum AST was 48.86${\pm}$7.46 IU/L before oriental medical treatment. After the treatment, 40.63${\pm}$4.69, 43.12${\pm}$5.46, 37.82${\pm}$4.52 IU/L were measured where although the level decreased to the normal level compared to pre-treatment, the value was not significant statistically(P>0.05). ALT was 66.26${\pm}$11.01 IU/L before oriental medical treatment. After the treatment 62.10${\pm}$8.20, 61.10${\pm}$8.76, 43.79${\pm}$5.68 were measured where although the level decreased, abnormally high level was maintained. The last result was significant statistically(P<0.05) compared to pre-treatment. ALP was 193.06${\pm}$14.20 IU/L before oriental medical treatment. After the treatment, 176.80${\pm}$6.48, 177.46${\pm}$11.81, 162.41${\pm}$9.06 where although compared to pre-treatment the last result was significant statistically(P<0.05), the change was within the normal range. ${\gamma}$-GGT was 87.83${\pm}$12.59 IU/L before oriental medical treatment. After the treatment, progressively near normal level was achieved with 118.73${\pm}$46.45, 85.03${\pm}$17.12, 70.64${\pm}$10.93 and the last result was statistically significant compared to pre-treatment (P<0.05). Blood triglyceride was 217.63${\pm}$32.18 mg/dL before oriental medical treatment. After treatment 215.09${\pm}$22.18, 189.93${\pm}$22.44, 191.22${\pm}$18.51 where abnormal values continued even after treatment although results was not statistically significant compared to pre-treatment(P>0.05). Total-cholesterol was 197.28${\pm}$9.24 mg/dL before oriental medical treatment, after treatment 201.55${\pm}$11.13, 186.87${\pm}$8.77 and 186.68${\pm}$7.61 were measured that results were not statistically significant compared to pre-treatment(P>0.05). HDL-cholesterol was 41.88${\pm}$2.38 mg/dL before oriental medical treatment, after treatment 48.75${\pm}$4.22, 44.10${\pm}$1.91, 48.00${\pm}$2.06 the results were not statistically significant compared to pre-treatment(P>0.05). LDL-cholesterol was 111.66${\pm}$13.08 mg/dL before oriental medical treatment, after treatment 109.94${\pm}$10.18, 101.79${\pm}$8.63, 104.00${\pm}$6.98 the results were not statistically significant compared to pre-treatment(P>0.05). With such results, even if common oriental medical treatments were given to metabolic syndrome patients with abnormal liver function, the liver function was confirmed not to be aggravated, and the concentration of lipids in the blood was confirmed not to be affected in most patients.

Analgesic and Anti-inflammatory Activity of Carissa carandas Linn fruits and Microstylis wallichii Lindl Tubers

  • Reddy, G.D.;Kaushik, Atul;Shanker, K.;Tiwari, R.K.;Mukherjee, Alok;Rao, Ch.V.;Sharma, Alok
    • Natural Product Sciences
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    • v.13 no.1
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    • pp.6-10
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    • 2007
  • The ethanolic (50% v/v) extracts of Carissa carandas (fruits) (Apocynaceae) and Microstylis wallichii (tubers) (Orchidaceae) were examined for anti-inflammatory and analgesic activities in experimental animals. Carissa carandas and Microstylis wallichii (50-200 mg/kg) caused a dose dependent inhibition of swelling caused by carrageenin significantly in cotton pellet induced granuloma in rats (P < 0.05 to P < 0.001). There was a significant increase in the analgesy meter induced pain in rats. The extracts of Carissa carandas and Microstylis wallichii resulted in an inhibition of stretching episodes and percentage protection was 16.05-17.58%respectively in acetic acid induced writhing.

Hybrid MIMO Antenna Using Interconnection Tie for Eight-Band Mobile Handsets

  • Lee, Wonhee;Park, Mingil;Son, Taeho
    • Journal of electromagnetic engineering and science
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    • v.15 no.3
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    • pp.185-193
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    • 2015
  • In this paper, a hybrid multiple input multiple output (MIMO) antenna for eight-band mobile handsets is designed and implemented. For the MIMO antenna, two hybrid antennas are laid symmetrically and connected by an interconnection tie, thereby enabling complementary operation. The tie affects both the impedance and radiation characteristics of each antenna. Further, printed circuit board (PCB) embedded type is applied to the antenna design. To verify the results of this study, we designed eight bands-LTE class 12, 13, and 14, CDMA, GSM900, DCS1800, PCS, and WCDMA-and implemented them on a bare board the same size as the real board of a handset. The voltage standing wave ratio (VSWR) is within 3:1 over the entire design band. Antenna isolation is less than -15 dB at the lower band, and -12 dB at the WCDMA band. Envelope correlation coefficient (ECC) of 0.0002-0.05 is obtained for all bands. The average gain and efficiency are measured to range from -4.69 dBi to -2.88 dBi and 33.99% to 51.5% for antenna 1, and -4.74 dBi to -2.97 dBi and 33.45% to 50.49% for antenna 2, respectively.

Performance of 3D printed plastic scintillators for gamma-ray detection

  • Kim, Dong-geon;Lee, Sangmin;Park, Junesic;Son, Jaebum;Kim, Tae Hoon;Kim, Yong Hyun;Pak, Kihong;Kim, Yong Kyun
    • Nuclear Engineering and Technology
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    • v.52 no.12
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    • pp.2910-2917
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    • 2020
  • Digital light processing three-dimensional (3D) printing technique is a powerful tool to rapidly manufacture plastic scintillators of almost any shape or geometric features. In our previous study, the main properties of light output and transmission were analyzed. However, a more detailed study of the other properties is required to develop 3D printed plastic scintillators with expectable and reproducible properties. The 3D printed plastic scintillator displayed an average decay time constants of 15.6 ns, intrinsic energy resolution of 13.2%, and intrinsic detection efficiency of 6.81% for 477 keV Compton electrons from the 137Cs γ-ray source. The 3D printed plastic scintillator showed a similar decay time and intrinsic detection efficiency as that of a commercial plastic scintillator BC408. Furthermore, the presented estimates for the properties showed good agreement with the analyzed data.

Direct Position Determination of Coherently Distributed Sources based on Compressed Sensing with a Moving Nested Array

  • Yankui, Zhang;Haiyun, Xu;Bin, Ba;Rong, Zong;Daming, Wang;Xiangzhi, Li
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.5
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    • pp.2454-2468
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    • 2019
  • The existing direct position determinations(DPD) for coherently distributed(CD) sources are mostly applicable for uniform linear array(ULA), which result in a low degree of freedom(DOF), and it is difficult for them to realize the effective positioning in underdetermined condition. In this paper, a novel DPD algorithm for coherently distributed sources based on compressed sensing with a moving nested array is present. In this algorithm, the nested array is introduced to DPD firstly, and a positioning model of signal moving station based on nested array is constructed. Owing to the features of coherently distributed sources, the cost function of compressed sensing is established based on vectorization. For the sake of convenience, unconstrained transformation and convex transformation of cost functions are carried out. Finally, the position coordinates of the distribution source signals are obtained according to the theory of optimization. At the same time, the complexity is analyzed, and the simulation results show that, in comparison with two-step positioning algorithms and subspace-based algorithms, the proposed algorithm effectively solves the positioning problem in underdetermined condition with the same physical element number.

Cross-Talk: D2D Potentiality Based Resource Borrowing Schema for Ultra-Low Latency Transmission in Cellular Network

  • Sun, Guolin;Dingana, Timothy;Adolphe, Sebakara Samuel Rene;Boateng, Gordon Owusu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.5
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    • pp.2258-2276
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    • 2019
  • Resource sharing is one of the main goals achieved by network virtualization technology to enhance network resource utilization and enable resource customization. Though resource sharing can improve network efficiency by accommodating various users in a network, limited infrastructure capacity is still a challenge to ultra-low latency service operators. In this paper, we propose an inter-slice resource borrowing schema based on the device-to-device (D2D) potentiality especially for ultra-low latency transmission in cellular networks. An extended and modified Kuhn-Munkres bipartite matching algorithm is developed to optimally achieve inter-slice resource borrowing. Simulation results show that, proper D2D user matching can be achieved, satisfying ultra-low latency (ULL) users' quality of service (QoS) requirements and resource utilization in various scenarios.

A Study on the Effect of Steel Fiber in Reinforced Concrete Coupling Beam Subjected to Cyclic Loading (반복하중을 받는 철근콘크리트 연결보에서 강섬유의 보강효과에 관한 연구)

  • Kim, Jin-Sung;Bae, Baek-Il;Choi, Chang-Sik
    • Journal of the Architectural Institute of Korea Structure & Construction
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    • v.35 no.10
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    • pp.181-190
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    • 2019
  • In this study, four reinforced concrete coupling beams were subjected to cyclic lateral loading test to evaluate the structural performance of coupling beam according to volume fraction of steel fiber. For this purpose, the volume fraction of steel fiber(0%, 1%, 2%) and transverse reinforcement spacing were determined as the main parameter. According to the test results, the maximum strength of D-40C-s100-0 was 1.15, 1.13, 1.05 times higher than D-40C-s300-0, D-40C-s300-1, D-40C-s300-2, respectively. The maximum strength of coupling beams with mitigated rebar details increases as the volume fraction of steel fiber increases. Although steel fiber 2% reinforced specimen(D-40C-s300-2) did not satisfy the amount of transverse reinforcement required for seismic design of coupling beam, the overall performance including to maximum strength, ductility and energy dissipation capacity was similar to the control specimen(D-40C-s100-0). As a result, the use of steel fiber with 2% reinforcement can partially replace the transverse reinforcement in diagonally reinforced concrete coupling beam.

Effect of reducing dietary crude protein level on growth performance, blood profiles, nutrient digestibility, carcass traits, and odor emissions in growing-finishing pigs

  • Aaron Niyonsaba;Xing Hao Jin;Yoo Yong Kim
    • Animal Bioscience
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    • v.36 no.10
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    • pp.1584-1595
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    • 2023
  • Objective: This study was conducted to evaluate the effect of a low-protein diet on growth performance, carcass traits, nutrient digestibility, blood profiles, and odor emissions in growing-finishing pigs. Methods: A total of 126 crossbred pigs ([Yorkshire×Landrace]×Duroc) with an average body weight (BW) of 38.56±0.53 kg were used for a 14-week feeding trial. Experimental pigs were allotted to one of 6 treatments in 3 replicates of 7 pigs per pen in a randomized complete block design. Pigs were fed each treatment diet with different levels of crude protein (CP). Phase 1 (early growing): 14%, 15%, 16%, 17%, 18%, 19%; phase 2 (late growing): 13%, 14%, 15%, 16%, 17%, 18%; phase 3 (early finishing): 12%, 13%, 14%, 15%, 16%, 17%; phase 4 (late finishing): 11%, 12%, 13%, 14%, 15%, 16%. All experimental diets in each phase were contained the same concentration of lysine (Lys), methionine (Met), threonine (Thr), and tryptophan (Trp). Results: Over the entire experimental period, there was no significant difference in BW, average daily feed intake, and gain-to-feed ratio among all treatments (p>0.05), but a quadratic effect (p = 0.04) was observed in average daily gain (ADG) during the late finishing phase with higher ADG in Group D. Blood urea nitrogen concentration linearly increased with an increase in dietary CP levels (p<0.01). Regarding nutrient digestibility, excreted nitrogen in urine and feces and nitrogen retention linearly increased as the CP level increased (p<0.01). A linear effect was observed with increasing CP levels in amines, ammonia, and hydrogen sulfide in odor emissions (p<0.01). No significant effects were observed in the measurements of carcass traits and meat characteristics (p>0.05). Conclusion: In phase feeding, reducing the CP level to 14% in early-growing pigs, 13% in late-growing pigs, 12% in early-finishing pigs, and 11% in late-finishing pigs is recommended.

Evaluation of the Milk Productivity and Nutrient Balance of Forage Sources for Organic Dairy Farms in Korea (유기 조사료 급여 농가의 영양소 균형 및 유생산성 평가)

  • Na, Y.J.;Shin, K.M.;Rim, J.S.;Bang, J.W.;Lee, S.R.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.2
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    • pp.98-103
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    • 2016
  • This study was conducted to evaluate the milk productivity and nutrient balance in organic dairy farms located at Gochang-gun of Korea with different feed sources. The total number of organic dairy farms was 12 in 2012, 13 in 2013, and 14 in 2014. The numbers of farms and dairy herds were increased each year. The average milk yields in 2012, 2013, and 2014 were 25.5, 24.6, and 24.4 kg/d, respectively. The average milk fat contents in 2012, 2013, and 2014 were 3.5%, 3.6%, and 3.7%, respectively. The average milk protein contents in 2012, 2013, and 2014 were 3.3%, 3.4%, and 3.4% in 2012, 2013, and 2014, respectively. Although the average milk yield of organic dairy farms was 9 kg/cows/d less than the average milk yield of other dairy farms in Korea, milk fat and protein contents of organic dairy farms were higher than those of other dairy farms. Alfalfa hay, oat hay, corn silage, rye grass silage, Sudan grass silage, rice straw, and barley silage were commonly used as forage sources in organic dairy farms. The average silage intake (15.6 kg/cow/d) of organic dairy farms in 2013 was higher (P < 0.05), while the average hay intake (5.1 kg/cow/d) in 2014 was higher (P < 0.05) than that of other feed intake. Net energy for lactation ($NE_L$) and metabolizable protein (MP) were calculated in accordance with NRC (2001). Net energy for lactation intake was higher (P < 0.05) while MP intake was lower (P < 0.05) than NRC recommendation values in 2013 and 2014. These results indicate that domestic organic dairy farms should use feed considering energy and protein balance recommended by NRC.

A Study on the Comparison of Chemical Characterization and Ellagic Acid Content Between Distribution Bokbunja and Korean Native Bokbunja (국내유통 복분자와 토종복분자의 이화학적 특성과 엘라그산 함량 비교연구)

  • Jung, Sung Hee;Yu, Hye Young;Seo, Ji Ho;Lee, Yong Jae;Han, Min Woo
    • Korean Journal of Plant Resources
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    • v.34 no.2
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    • pp.177-185
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    • 2021
  • The purpose of this study was to compare the chemical properties of the bokbunja distributed in Korea with the content of the bioactive substance ellagic acid. The bokbunja was Rubus coreanus group and Rubus occidentalis group were compared, domestic bokbunja and import bokbunja were compared. In bokbunja, free sugar was 30.89 ± 0.7 mg/g of Rubus coreanus and 29.05 ± 0.87 mg/g of Rubus occidentalis. and 27.28 ± 7.4 mg/g of domestic bokbunja and 21.58 ± 6.73 mg/g of import bokbunja. The free amino acids was 4.50 ± 0.08 mg/g of Rubus coreanus and 5.05 ± 0.08 mg/g of Rubus occidentalis. and 4.13 ± 1.09 mg/g of domestic bokbunja and 3.75 ± 0.31 mg/g of import bokbunja. Validation of the ellagic acid method was confirmed by comparing the retention time and spectrum of the standard and extract using HPLC. The calibration curve (R2) showed linearity of 0.9999. As a result of analyzing the ellagic acid content of each extraction solvent, DMSO and methanol mixture extracts were high, and Rubus coreanus was 2.56 mg/g and Rubus occidentalis was 3.16 mg/g, which was not significantly different (p < 0.05) In addition, the ellagic acid content of domestic bokbunja and import bokbunja was 2.83 mg/g and 2.99 mg/g, which was not significantly different (p < 0.05).