• 제목/요약/키워드: 12-deacetoxy-23-deacetoxyscalarin

검색결과 1건 처리시간 0.015초

Scalaran-type sesterterpenes from a Marine Sponge Smenospongia species showing the AMPK activation

  • Hwang, Buyng-Su;Rho, Jung-Rae
    • 한국자기공명학회논문지
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    • 제16권1호
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    • pp.1-10
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    • 2012
  • A new scalaran class sesterterpenoid with five known ones was isolated from a marine sponge Smenospongia species collected from the Gageo island, Korea. Chemical structure of all of compounds was determined on the basis of a combination of extensive 1D and 2D NMR experiments and MS data. The new compound exhibited a new functional group on a common scalaran sesterterpene skeleton, identified as 12-deacetoxy-23-deacetoxyscalarin. The compound 1 moderately showed the effect of the activation of AMP-activated protein kinase (AMPK) in L6 myoblast cell.