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Different Metabolic Patterns of Parkinsonism: Analysed by Statistical Parametric Mapping (통계적 파라미터를 이용한 Parkinsonism의 Metabolic pattern 분석)

  • 주라형;김재승;최보영;문대혁;서태석
    • Progress in Medical Physics
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    • v.14 no.2
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    • pp.108-123
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    • 2003
  • The purpose of this study is to evaluate the contribution of $^{18}$ F-FDG brain PET in the differentiating Idiopathic parkinson's diesease (IPD), progressive supranuclear palsy (PSP), and multiple system atrophy (MSA). We studied 24 patients with parkinsonism : 8 patients (mean age 67.9$\pm$10.7 y: M/F : 3/5) with IPD, 9 patients (57.9$\pm$9.2 y : M/F : 4/5) with MSA and 7 patients (67.6$\pm$4.8 y : M/F 3/4) with PSP. All patients with parkinsonism and 22 age-matched normal controls underwent $^{18}$ F FDG PET in 3D mode after the injection of 370 MBq $^{118}$ F FDG. The patients with IPD, MSh and PSP were compared with a normal control group by a two-sided t-test of SPM99 (uncorrected P<0.001, extent threshold>100 voxel). All three parkinsonism groups, showed significant hypometabolism in the cerebral neocortex compared to the normal control group. However, the three groups displayed different metabolism in the subcortical structure, brain stem, and cerebellum. In IPD, there was no significant hypometabolism in the putamen, brain stem and cerebellum. However, MSA patients showed significant hypometabolism in the striatum, pons, and cerebellum compared to the normal controls and IPD patients. In addition, PSP showed significant hypometabolism in the caudate nuclei, the thalamus, midbrain, and the cingulate gyrus compared to the normal controls, the IPD, and MSA groups (IPD vs Normal sensitivity/specificity : 75%/l00%, MSA vs Normal sensitivity/specificity :100%/87%, PSP vs Normal sensitivity/specificity : 86%/94%). Our results show that the regional metabolism of IPD, MSA, and PSP is different mainly in the striatum, thalamus, brain stem and cerebellum. An assessment of the $^{18}$ F-FDG PET scan images using SPM may be a useful adjunct to a clinical examination in making a differential diagnosis of Parkinsonism.

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The Characteristics of Retention and Evapotranspiration in the Extensive Greening Module of Sloped and Flat Rooftops (저토심 경사지붕과 평지붕 녹화모듈의 저류 및 증발산 특성)

  • Ryu, Nam-Hyong;Lee, Chun-Seok
    • Journal of the Korean Institute of Landscape Architecture
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    • v.41 no.6
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    • pp.107-116
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    • 2013
  • This study was undertaken to investigate the characteristics of retention and evapotranspiration in the extensive greening module of sloped and flat rooftops for stormwater management and urban heat island mitigation. A series of 100mm depth's weighing lysimeters planted with Sedum kamtschaticum. were constructed on a 50% slope facing four orientations(north, east, south and west) and a flat rooftop. Thereafter the retention and evapotranspiration from the greening module and the surface temperature of nongreening and greening rooftop were recorded beginning in September 2012 for a period of 1 year. The characteristics of retention and evapotranspiration in the greening module were as follows. The water storage of the sloped and flat greening modules increased to 8.7~28.4mm and 10.6~31.8mm after rainfall except in the winter season, in which it decreased to 3.3mm and 3.9mm in the longer dry period. The maximum stormwater retention of the sloped and flat greening modules was 22.2mm and 23.1mm except in the winter season. Fitted stormwater retention function was [Stormwater Retention Ratio(%)=-18.42 ln(Precipitation)+107.9, $R^2$=0.80] for sloped greening modules, and that was [Stormwater Retention Ratio(%)=-22.64 ln(X)+130.8, $R^2$=0.81] for flat greening modules. The daily evapotranspiration(mm/day) from the greening modules after rainfall decreased rapidly with a power function type in summer, and with a log function type in spring and autumn. The daily evapotranspiration(mm/day) from the greening modules after rainfall was greater in summer > spring > autumn > winter by season. This may be due to the differences in water storage, solar radiation and air temperature. The daily evapotranspiration from the greening modules decreased rapidly from 2~7mm/day to less than 1mm/day for 3~5 days after rainfall, and that decreased slowly after 3~5 days. This indicates that Sedum kamtschaticum used water rapidly when it was available and conserved water when it was not. The albedo of the concrete rooftop and greening rooftop was 0.151 and 0.137 in summer, and 0.165 and 0.165 in winter respectively. The albedo of the concrete rooftop and greening rooftop was similar. The effect of the daily mean and highest surface temperature decrease by greening during the summer season showed $1.6{\sim}13.8^{\circ}C$(mean $9.7^{\circ}C$) and $6.2{\sim}17.6^{\circ}C$(mean $11.2^{\circ}C$). The difference of the daily mean and highest surface temperature between the greening rooftop and concrete rooftop during the winter season were small, measuring $-2.4{\sim}1.3^{\circ}C$(mean $-0.4^{\circ}C$) and $-4.2{\sim}2.6^{\circ}C$(mean $0.0^{\circ}C$). The difference in the highest daily surface temperature between the greening rooftop and concrete rooftop during the summer season increased with an evapotranspiration rate increase by a linear function type. The fitted function of the highest daily surface temperature decrease was [Temperature Decrease($^{\circ}C$)=$1.4361{\times}$(Evapotranspiration rate(mm/day))+8.83, $R^2$=0.59]. The decrease of the surface temperature by greening in the longer dry period was due to sun protection by the sedum canopy. The results of this study indicate that the extensive rooftop greening will assist in managing stormwater runoff and urban heat island through retention and evapotranspiration. Sedum kamtschaticum would be the ideal plant for a non-irrigated extensive green roof. The shading effects of Sedum kamtschaticum would be important as well as the evapotranspiration effects of that for the long-term mitigation effects of an urban heat island.

전자부품의 냉각을 위한 자연대류 상관 관계식의 평가

  • 이재헌
    • Journal of the KSME
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    • v.27 no.6
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    • pp.504-514
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    • 1987
  • 복잡한 전자부품의 조립시에 필요한 열적 디자인에 관한 정보는 오래전부터 실험을 통하여 얻어지고 있다. 실험적 데이터를 이용하여 무차원 파라미터로 표시된 실험결과는 꼭 같지는 않지만 현상적으로는 비슷한 상황에 응용될 수 있다. 여기서는 학술문헌에 나타나 있는 자연대류에 관한 실험적인 상관관계식들과 프레임에 수직으로 꽂혀있는 균일가열 전자회로기판의 모델에서 얻어진 무차원 자료들을 비교하고자 한다. 대부분의 자료들은 수정채널 Rayleigh수(Ra")가 15~100범위에 속하며, 이러한 범위는 부품이 조밀하게 배치된 기관이 서로 좁은 채널을 이루고 있으며, 동시에 상당한 전력을 소비하고 있는 경우에 해당한다. Wirt와 Stutzman, Bar-Cohen과 Rohsenow의 일반상관관계식은 AT'||'&'||'T Bell 연구소에서 개발된 전자기기를 이용하여 수집한 실험데이터를 잘 표현하고 있으며 10 < Ra" <1,000범위에서 추천될 수 있다. 두개의 유사한 상관관계식과 비교할 때 상당히 좋은 예측을 보였으며 또한 Sparrow와 Gregg의 연구결과와도 잘 일치하므로 Ra" < 10인 경우에 Aung의 완전발달층류의 채널유동방식, Ra" > 1,000인 경우에는 Aung등의 단일 수직평판 근사식이 추천될 수 있다. Coyne의 알고리즘에 의한 계산치는 10

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A Study on the Effectiveness of Gas Safety Devices for Domestic (가정용 가스안전기기의 실효성에 관한 연구)

  • Jo Young-Do;Lee Kyung-Sik;Jang Sung-Dong;Kim Ji-Yun
    • Journal of the Korean Institute of Gas
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    • v.5 no.4 s.16
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    • pp.62-69
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    • 2001
  • Gas safety devices are very effective to prevent catastrophic gas accident in domestic. The safety devices are included in domestic gas equipment such as extinguishing safety device and adapted at pipeline such as fuse cock, shut off device with gas alarm and so forth. In spite of using those safety devices, a few hundreds of gas accident was happened annually in residential house. In this study, we analysed systematically the domestic accidents which was happened in five years using fault tree analysis(FTA) method and analysed the effectiveness of individual safety device. And also, it was suggested that the rate of accident was decreased quantitatively by increasing safety device which is adapted in domestic. By analysis of 769 gas accidents in domestic, the order of effectiveness of safety device to prevent domestic gas accident was the multi-functional gas-safe-meter(micom-meter), fuse cock, gas leak alarm and CO alarm. If the above four kind of safety device are adapted to every house, about $59\%$ of accident will be reduced and the most of catastrophic gas accident will be Prevented in domestic.

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Fast Generation of Elliptic Curve Base Points Using Efficient Exponentiation over $GF(p^m)$) (효율적인 $GF(p^m)$ 멱승 연산을 이용한 타원곡선 기저점의 고속 생성)

  • Lee, Mun-Kyu
    • Journal of KIISE:Computer Systems and Theory
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    • v.34 no.3
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    • pp.93-100
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    • 2007
  • Since Koblitz and Miller suggested the use of elliptic curves in cryptography, there has been an extensive literature on elliptic curve cryptosystem (ECC). The use of ECC is based on the observation that the points on an elliptic curve form an additive group under point addition operation. To realize secure cryptosystems using these groups, it is very important to find an elliptic curve whose group order is divisible by a large prime, and also to find a base point whose order equals this prime. While there have been many dramatic improvements on finding an elliptic curve and computing its group order efficiently, there are not many results on finding an adequate base point for a given curve. In this paper, we propose an efficient method to find a random base point on an elliptic curve defined over $GF(p^m)$. We first show that the critical operation in finding a base point is exponentiation. Then we present efficient algorithms to accelerate exponentiation in $GF(p^m)$. Finally, we implement our algorithms and give experimental results on various practical elliptic curves, which show that the new algorithms make the process of searching for a base point 1.62-6.55 times faster, compared to the searching algorithm based on the binary exponentiation.

Load Fidelity Improvement of Piecewise Integrated Composite Beam by Construction Training Data of k-NN Classification Model (k-NN 분류 모델의 학습 데이터 구성에 따른 PIC 보의 하중 충실도 향상에 관한 연구)

  • Ham, Seok Woo;Cheon, Seong S.
    • Composites Research
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    • v.33 no.3
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    • pp.108-114
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    • 2020
  • Piecewise Integrated Composite (PIC) beam is composed of different stacking against loading type depending upon location. The aim of current study is to assign robust stacking sequences against external loading to every corresponding part of the PIC beam based on the value of stress triaxiality at generated reference points using the k-NN (k-Nearest Neighbor) classification, which is one of representative machine learning techniques, in order to excellent superior bending characteristics. The stress triaxiality at reference points is obtained by three-point bending analysis of the Al beam with training data categorizing the type of external loading, i.e., tension, compression or shear. Loading types of each plane of the beam were classified by independent plane scheme as well as total beam scheme. Also, loading fidelities were calibrated for each case with the variation of hyper-parameters. Most effective stacking sequences were mapped into the PIC beam based on the k-NN classification model with the highest loading fidelity. FE analysis result shows the PIC beam has superior external loading resistance and energy absorption compared to conventional beam.

Study on Local Wireless Network Data Structure for Sludge Multimeter (슬러지 멀티미터를 위한 근거리무선네트워크 데이터구조 설계 연구)

  • Jung, Soonho;Kim, Younggi;Lee, Sijin;Lee, Sunghwa;Park, Taejun;Byun, Doogyoon;Cha, Jaesang
    • Journal of Satellite, Information and Communications
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    • v.9 no.2
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    • pp.96-100
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    • 2014
  • Recently, the management system of wastewater treatment facility has magnified due to the stringent regulations for the protection of the environment, and a sewage treatment plant efficiency and research of the car development are activated in large facilities or industrial park. however, the existing sewerage disposal system and specific water quality monitoring network reliability for real-time transmission of this building is insufficient. In this paper, we proposed a local wireless network design for sludge multi meter data collection and control for measuring the concentration of the sludge efficiently. Also, the collected data over the local wireless network to transmitted to the central monitoring system and accumulate the data in real time to calculate statistics is possible to monitor the status of the sewage treatment facilities. The proposed system uses a short-range wireless networks of IEEE 802.15.4 and configures an IEEE 802.11 network which can monitor real-time status in central system. Also, we install a sludge multimeter and communication network in sewage treatment facilities and confirm the usefulness of the proposed technique by demonstrating its effectiveness.

Current Status and Characterization of CANDU Spent Fuel for Geological Disposal System Design (심지층 처분시스템 설계를 위한 중수로 사용후핵연료 현황 및 선원항 분석)

  • Cho, Dong-Keun;Lee, Seung-Woo;Cha, Jeong-Hun;Choi, Jong-Won;Lee, Yang;Choi, Heui-Joo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.2
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    • pp.155-162
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    • 2008
  • Inventories to be disposed of, reference turnup, and source terms for CANDU spent fuel were evaluated for geological disposal system design. The historical and projected inventory by 2040 is expected to be 14,600 MtU under the condition of 30-year lifetime for unit 1 and 40-year lifetime for other units in Wolsong site. As a result of statistical analysis for discharge burnup of the spent fuels generated by 2007, average and stand deviation revealed 6,987 MWD/MtU and 1,167, respectively. From this result, the reference burnup was determined as 8,100 MWD/MtU which covers 84% of spent fuels in total. Source terms such as nuclide concentration for a long-term safety analysis, decay heat, thermo-mechanical analysis, and radiation intenity and spectrum was characterized by using ORIGEN-ARP containing conservativeness in the aspect of decay heat up to several thousand years. The results from this study will be useful for the design of storage and disposal facilities.

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Fabrication and Electrical Property Analysis of [(Ni0.3Mn0.7)1-xCux]3O4 Thin Films for Microbolometer Applications (마이크로볼로미터용 [(Ni0.3Mn0.7)1-xCux]3O4 박막의 제작 및 전기적 특성 분석)

  • Choi, Yong Ho;Jeong, Young Hun;Yun, Ji Sun;Paik, Jong Hoo;Hong, Youn Woo;Cho, Jeong Ho
    • Journal of Sensor Science and Technology
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    • v.28 no.1
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    • pp.41-46
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    • 2019
  • In order to develop novel thermal imaging materials for microbolometer applications, $[(Ni_{0.3}Mn_{0.7})_{1-x}Cu_x]_3O_4$ ($0.18{\leq}x{\leq}0.26$) thin films were fabricated using metal-organic decomposition. Effects of Cu content on the electrical properties of the annealed films were investigated. Spinel thin films with a thickness of approximately 100 nm were obtained from the $[(Ni_{0.3}Mn_{0.7})_{1-x}Cu_x]_3O_4$ films annealed at $380^{\circ}C$ for five hours. The resistivity (${\rho}$) of the annealed films was analyzed with respect to the small polaron hopping model. Based on the $Mn^{3+}/Mn^{4+}$ ratio values obtained through x-ray photoelectron spectroscopy analysis, the hopping mechanism between $Mn^{3+}$ and $Mn^{4+}$ cations discussed in the proposed study. The effects of $Cu^+$ and $Cu^{2+}$ cations on the hopping mechanism is also discussed. Obtained results indicate that $[(Ni_{0.3}Mn_{0.7})_{1-x}Cu_x]_3O_4$ thin films with low temperature annealing and superior electrical properties (${\rho}{\leq}54.83{\Omega}{\cdot}cm$, temperature coefficient of resistance > -2.62%/K) can be effectively employed in applications involving complementary metal-oxide semiconductor (CMOS) integrated microbolometer devices.

The French Evolution of Protection-Management Systems for Historic Monuments and Their Surroundings over One-Hundred Years: 1913-2016 (프랑스 역사기념물과 그 주변 보호·관리제도의 진화: 1913~2016)

  • Lee, Sujin;Ryu, Je-hun
    • Korean Journal of Heritage: History & Science
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    • v.52 no.3
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    • pp.94-111
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    • 2019
  • This study aims to examine the evolutionary process of the protection-management system for historic monuments and their surroundings in France over one-hundred years. Because France and Korea shared policies and institutions regarding the management of historical monuments (cultural property) along with their surroundings, it is necessary to explore the French experience from a comparative perspective. In France, historical monuments began to be recognized as national heritage according to "the 1913 law" which has continued to evolve for more than one hundred years. In the beginning, a historical monument was preserved as a single building unit; however, since 1943, a new policy has been implemented to preserve sets of historical monuments along with their perimeters of protection zones. Moreover, since 1980, in the context of decentralization, local authorities have been given more roles and autonomy concerning the management of historic monuments and their surroundings. Local authorities have played a key role in the protection-management of historic monuments and their surroundings, and have become more active in the conservation of their architectural heritage, including historic monuments. The central government, however, remains as the headquarters whose rigorous policies provide a solid foundation for the decentralized management system of architectural and cultural heritage, including historic monuments. The final goal in the evolutionary process, then, targets the effective and harmonious integration of the protection-management system for historic monuments and their surroundings into urban and regional planning.