• 제목/요약/키워드: 1-131 therapy

검색결과 192건 처리시간 0.03초

갑상선암의 고용량 $^{131}I$ 치료 시 입원기간의 최적화방안 연구 (A Study on Ways to Optimize the Period of Hospitalization During High-Dose $^{131}I$ Treatment of the Thyroid Cancer)

  • 백성민;고성진;김창수;김정훈;강세식
    • 대한방사선기술학회지:방사선기술과학
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    • 제33권3호
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    • pp.269-276
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    • 2010
  • 본 연구는 고용량 방사성옥소 치료환자의 선량률을 거리와 시간대별로 산출하여 방사성옥소 치료를 위한 입원기간의 최적화와 개선방안을 제한 하고자 하였다. 그 결과 100 mCi 고용량 옥소치료환자의 24시간 후에 배꼽에서 $1,035{\mu}Sv/hr$, 50 cm에서 $109{\mu}Sv/hr$, 100 cm에서 $33{\mu}Sv/hr$로 감쇠 되었다. 150 mCi 고용량 옥소치료환자의 24시간 후에 배꼽에서 $637{\mu}Sv/hr$, 50 cm에서 $100{\mu}Sv/hr$, 100 cm에서 $40{\mu}Sv/hr$로 감쇠 되었다. 180 mCi 고용량 옥소치료환자의 24시간 후에 배꼽에서 $1,251{\mu}Sv/hr$, 50 cm에서 $140{\mu}Sv/hr$, 100 cm에서 $56{\mu}Sv/hr$로 감쇠 되었다. 퇴원기준을 미국 원자력 규제위원회 고시에 $70.4{\mu}Sv/hr$이므로 본 연구 결과보다 빠른 퇴원이 가능하다. 치료 환자들의 계속적인 증가 추세로 볼 때 치료병실의 부족을 해소 할 수 있다.

침을 이용한 전기자극 통증치료 (Electric Stimulation for Pain Relief Using Acupuncture Needles)

  • 신근만;홍순용;최영룡
    • The Korean Journal of Pain
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    • 제5권1호
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    • pp.52-56
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    • 1992
  • For pain relief my collegue and I used thin acupuncture needles as electrodes in electric stimulation. The needles were inserted into a trigger point and into another point located in the same muscle instead of meridian points of electro-acupuncture. Low frequency electric stimulation was given through the needles to 130 patients for 15 min. The results were as follows In 25 acute sprain patients electric stimulation was given $3.14{\pm}1.12$ times and the pain was reduced on the average by $83.00{\pm}6.77%$ (VAS). In 45 chronic sprain patients electric stimulation was given $5.51{\pm}1.38$ times and the pain was reduced on the average by $70.22{\pm}8.98%$ (VAS). In 28 myofascial pain syndrome patients electric stimulation was given $6.22{\pm}1.25$ times and the pain was reduced on the average by $66.48{\pm}8.75$(%). In 7 muscle contraction headache patients electric stimulation was given $4.14{\pm}1.57$ times and the pain was reduced on the average by $75.00{\pm}9.57%$ (VAS). In 25 radiculopathy patients electric stimulation was given $4.73{\pm}1.131$ times and the pain was reduced on the average by $21.37{\pm}9.31%$ (VAS). We he conclude that electric stimulation therapy using acupuncture needles is very effective in acute sprain, chronic sprain, myofascial pain syndrome and muscle contraction headache. Any doctor with knows anatomy and trigger points can practice this method without studying oriental medicine or difficult acupuncture techniques.

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방사성 요오드 치료환자의 환의 및 시트에 대한 재사용주기 평가 (The Evaluation on Reuse Period of Patient's Clothes and Sheet After Radioiodine Therapy)

  • 김영선;서명덕;이완규;김기준;송재범
    • 핵의학기술
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    • 제16권2호
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    • pp.12-17
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    • 2012
  • 방사성 요오드 치료병실에서 나온 환의 및 시트는 본디 방사성폐기물로서 관련 규정에 따라 일반 쓰레기와 동일하게 처리해야 하지만 사정상 일정기간 보관하여 방사능을 감쇄시킨 후 재사용하게 된다. 통상 최소보관기간 산출에 표면오염도(Bq/$m^2$)를 기반으로 하는 반출기준을 적용하고 있다. 하지만 방사선측정기를 이용하여 단위 면적당 총방사능량을 구하는 방법은 측정방법에 따라 편차와 불확실성이 상당히 커진다. 본 연구에서는 '방사성폐기물 자체처분 등에 관한 규정'에서 제시하고 있는 핵종 농도(Bq/g)를 Dose Calibrator를 이용하여 직접 측정하여 최소보관기간을 구함으로써, 환의 및 시트의 정확한 재사용 주기를 산출하고자 한다. 한편 반출기준으로 산출한 최소보관기간과 비교하여 그 차이를 살펴보았다. 본원의 방사성 요오드 치료병실에서 2011년 7월부터 2012년 3월까지 I-131을 3.7 GBq (100 mCi) 이상을 사용하여 방사성 요오드 치료를 시행한 환자 31명이 사용한 환의와 시트의 방사선 오염도를 측정하여 최소보관기간을 산출하였다. 최소보관기간은 핵종 농도를 측정하여 '방사성폐기물 자체처분 등에 관한 규정'에 따라 100 Bq/g이 되는 시점과 표면오염도를 측정하여 반출기준에 따라 허용표면오염도의 1/10, 즉 4 kBq/$m^2$되는 시점을 붕괴식에 대입하여 산출하였다. 반출기준으로 산출한 최소보관기간은 침대/담요시트는 14.2일, 베개시트는 4.6일, 환의(상(上))은 63일, 환의(하(下))는 78일 이었으며, 자체처분 기준에 따른 최소보관기간은 베개시트는 18.1일, 환의(상(上))은 43일, 환의(하(下))는 62일로 산출되었다. 표면오염도와 핵종 농도의 상관관계를 분석해 본 결과 베개시트와 환의(상(上))는 상관관계가 높게 나타났으나, 환의(하)는 낮게 나타났다. 이는 베개시트와 환의는 방사성오염이 부분에 국한 되어 측정값이 일정한 반면, 환의(하(下))는 소변에 의한 방사성오염이 여러 부분에 산재되어 있어 방사선측정기의 측정값이 상대적으로 낮게 측정된 결과로 생각 된다. 실질적으로 방사성 오염도를 측정한 결과 반출기준과 자체처분 기준을 상당량 초과하는 방사능이 존재하는 것을 확인할 수 있었다. 환의와 시트의 최소보관기간 산출에는 핵종 농도를 기준으로 하는 자체처분 기준을 적용하는 것이 더 적합하다고 할 수 있다. 방사능에 오염된 환의 및 시트는 최소 60일 정도는 보관해야 성급한 재사용에 따른 불필요한 방사선피폭 및 오염 확산을 방지할 수 있을 것으로 생각된다.

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단축감각프로파일의 타당성 연구 (A Study on the Validity of Short Sensory Profile for Children Without Disability)

  • 김경미
    • 대한감각통합치료학회지
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    • 제2권1호
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    • pp.1-10
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    • 2004
  • Objective : The purpose of this study were to examine internal reliability and internal validity for Short Sensory Profile(SSP) and to suggest the useful criteria for sensory processing abilities in Korean culture. Methods : The Short Sensory Profile(SSP) was completed by mothers of 304 children typically developing between 3 to 10 years of age in those preschool, kindergarten and elementary school located Seoul and Gyeonggi-do. The total agency for this study was 14 facilities and the period of study was from July, 2002 to June, 2003. Kim Mi Sun(2001) translated and modified the Short Sensory Profile that Macintoshi developed and the tool for the study was used. The data were analyzed with reliability test and Pearson's correlation. Results : 1. Internal reliability of the total tests and sections was estimated by calculating Cronbach's Alphas. Reliability value of the total tests was .889. 2. For internal validity the correlations range from .131 to .575 in magnitude, suggesting that the sections of the Short Sensory Profile tap relatively unique constructs and support the factor structure developed. 3. The total score of the Short Sensory Profile(SSP) range from 118 to 190, mean and SD was 163.12, 14.87. 4. Of 403 children represented by the survey, 32 children(10.5%) met criteria for sensory processing disorders based upon parental perceptions. 5. Cut scores were determined by computing the raw score cut scores for -1 SD and -2 SD. The normal group of sensory processing abilities had score which range from 190 to 149, the probable problem group had score which range from 148 to 134, and the definite problem group had score which range from 133 to 138. Conclusion : Findings from the above study suggest that Short Sensory Profile be the screening tool for sensory processing disorders within Korean culture. Further research is needed to compare with children with the various sensory processing disabilities(PDD, LD, CP ect,).

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Effects of PTTG Down-regulation on Proliferation and Metastasis of the SCL-1 Cutaneous Squamous Cell Carcinoma Cell Line

  • Xia, Yong-Hua;Li, Min;Fu, Dan-Dan;Xu, Su-Ling;Li, Zhan-Guo;Liu, Dong;Tian, Zhong-Wei
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권11호
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    • pp.6245-6248
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    • 2013
  • Aims: To study effects of down-regulation of pituitary tumor-transforming gene (PTTG) on proliferation and metastasis ability of the SCL-1 cutaneous squamous cell carcinoma (CSCC) cell line and explore related mechanisms. Methods: SCL-1 cells were divided into 3 groups (untreated, siRNA control and PTTG siRNA). Cell proliferation assays were performed using a CCK-8 kit and proliferation and metastasis ability were analyzed using Boyden chambers. In addition, expression of MMP-2 and MMP-9 was detected by r-time qPCR and Western blotting. Results: Down-regulation of PTTG could markedly inhibit cell proliferation in SCL-1 cells, compared to untreated and control siRNA groups (P < 0.05). Real-time qPCR demonstrated that expression levels of PTTG, MMP-2 and MMP-9 in the PTTG siRNA group were 0.8%, 23.2% and 21.3% of untreated levels. Western blotting revealed that expression of PTTG, MMP-2 and MMP-9 proteins in the PTTG siRNA group was obviously down-regulated. The numbers of migrating cells ($51.38{\pm}4.71$) in the PTTG siRNA group was obviously lower than that in untreated group ($131.33{\pm}6.12$) and the control siRNA group ($127.72{\pm}5.20$) (P < 0.05), suggesting that decrease of proliferation and metastasis ability mediated by PTTG knock-down may be closely correlated with down-regulation of MMP-2 and MMP-9 expression. Conclusion: Inhibition of PTTG expression may be a new target for therapy of CSCC.

성대마비와 성대구증의 강도 변화에 따른 최대발성지속시간 비교 (Comparison of Maximum Phonation Time Associated with the Changes in Vocal Intensity in Patients with Unilateral Vocal Fold Palsy and Sulcus Vocalis)

  • 최세진;최홍식;김재옥;최예린
    • 말소리와 음성과학
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    • 제4권1호
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    • pp.125-131
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    • 2012
  • The patients with incomplete glottic closure have an important feature decreasing the maximum phonation time (MPT) because airflow rate or air leakage is greater than people without voice disorders. Also they can appear a problem in the intensity regulation. This study analyzed MPT difference based on the comfortable intensity and louder intensity and the correlation between MPT and respiration volume of unilateral vocal fold palsy (UVFP) and sulcus vocalis (SV) group. The twenty with UVFP, the 21 with SV, the 21 normal subjects measured MPT in /a/ vowel prolongation task with comfortable intensity and louder intensity and compared analysis by measuring FVC, $FEV_1$, $FEV_1/FVC$ to analyze the correlation between MPT and respiration volume. First, a comparison of MPT according to the intensity between groups is that MPT of the normal group was statistically significant long compared to the patient group in comfortable intensity, but MPT between groups was not statistically significant difference in the louder intensity. Second, an analysis of the correlation between MPT and respiration volume is that this was statistically significant correlation between MPT in comfortable intensity and MPT in louder intensity. But this did not show statistically significant correlation between intensity and respiration volume. This study can be supported the preceding study results deduced that shorting MPT of the patient group compared to the normal group was originated in the problem of laryngeal valving mechanism at the level of vocal folds rather than a problem of respiratory function. Also at the phonation by varying the intensity, the result can deduce that in the case of patient group, the length of MPT had been improved by increasing the glottal closure ratio in the louder intensity. These results can support the theoretical basis that should be applied to the clinicians by varying the intensity at the voice evaluation and voice therapy for the patients with the glottis incompetence.

취약계층을 위한 정보통신 접근성 정책에 대한 국가 간 비교 연구 -관련제도 중심으로- (Comparative Research on Global Policy in ICT Accessibility for Vulnerable Groups -Focusing on Implementation of Legislative System-)

  • 김중연;박성우;강병권;손창용;정봉근
    • 재활복지
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    • 제20권1호
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    • pp.131-150
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    • 2016
  • 본 연구에서는 서방 선진국을 포함한 주요 아시아 국가의 사회적 취약계층을 위한 정보통신 접근성 향상 관련 정책들을 비교 분석하여 우리나라에서 시행되고 있는 정책 개선을 위한 시사점을 도출하고자 하였다. 연구 결과 대한민국은 아시아 국가에 비해 법과 표준이 잘 정비되어 실효성이 높은 반면 서방국가들과의 비교에서는 상대적으로 관련 정책들의 개선이 필요한 것으로 나타났다. 급변하는 정보통신기술에 대한 새로운 정의들을 관련법이 명확히 반영하는데 한계를 보였으며 웹 및 모바일 애플리케이션 접근성 이외의 정책 및 표준 제정이 미흡하였다. 이에 대한 개선을 위해 법 제 개정 주기를 단축하고 정보통신 접근성 관련 시나리오를 사전에 연구 개발, 필요시 즉시 적용할 수 있도록 정부 산하의 전문연구기관을 설립하는 방법들을 고려해볼 수 있을 것이다. 사회취약계층은 정보통신에 대한 접근성을 보장받지 못하고 정보를 잘 활용하는 사람들과 구별되어 사회, 경제, 문화 등 삶의 많은 측면에서 차별을 받고 있는 실정이다. 이러한 차별 해소를 위해서는 정부의 지원과 관련 업계의 자발적인 참여 및 국민의 관심이 지속이 뒷받침 되어야 할 것이다.

Survival rate of modern all-ceramic FPDs during an observation period from 2011 to 2016

  • Pott, Philipp-Cornelius;Eisenburger, Michael;Stiesch, Meike
    • The Journal of Advanced Prosthodontics
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    • 제10권1호
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    • pp.18-24
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    • 2018
  • PURPOSE. In literature, many studies compare survival rates of different types of FPDs. Most of them compared restorations, which originated from one university, but from different clinicians. Data about restoration survival rates by only one experienced dentist are very rare. The aim of this study was to evaluate the survival rate of all-ceramic FPDs without the blurring effects of different clinicians. MATERIALS AND METHODS. 153 veneered-zirconia FPDs were observed for follow-up. 22 patients received 131 single crowns and 22 bridges. Because of the different bridge lengths, one unit was defined as a restored or replaced tooth. In total, 201 units were included. Only the restorations performed by the same clinician and produced in the same dental laboratory from 2011 to 2016 were included. Considered factors were defined as "type of unit", "type of abutment", "intraoral region", and "vitality". Modified UHPHS criteria were used for evaluation. Statistical analysis was performed using cox-regression. RESULTS. 189 units (94.0%) showed no kind of failure. 5 chippings (2.4%) could be corrected by intraoral polishing. 4 units (1.9%) exhibited spontaneous decementation. These polishable and recementable restorations are still in clinical use. Chippings or decementations, which lead to total failure, did not occur. One unit was completely fractured (0.5 %). Biological failures (caries, periodontitis or periimplantitis) did not occur. The statistical analysis of the factors did not reveal any significant differences. CONCLUSION. Modern all-ceramic FPDs seem to be an appropriate therapy not only for single restorations but for complex occlusal rehabilitations.

음향학적 분석을 통한 뇌성마비 아동의 호흡 및 구강 운동 전.후 치료 효과 (The Effect of the Treatment on the Pre- and Post Respiration and the Oral Motor for Children with Cerebral Palsy by Acoustic Analysis)

  • 김숙희;김현기;신용일
    • 음성과학
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    • 제15권2호
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    • pp.131-141
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    • 2008
  • The purpose of this study was to find out the acoustic variation on the pre-and post respiration and oral motor for children with cerebral palsy. Five children with spastic CP at the age of 6 in average were practiced by a caregiver at home each for 25 minutes, in total, 45 times. The sustained of vowel /a/ and vowels /a/, /i/, /u/, /e/, /o/ were recorded on CSL and MDVP and analyzed by acoustic parameters. As a result, the maximum phonation time(MPT) was increased from 2.06 to 6.31 and the formant of vowels(F1, F2, F3) had significant differences in F1(/a, i/), F2(/i.u.o/), and F3(/a/) between the controls and the children with CP in pre-treatment. The total average value of vowels had significant differences between the pre-and post-treatment (p< .05). The energy of vowels had significant differences in the vowels /i, u, e, o/ and the total average value between the pre-and post-treatment(p< .001). The jitter percent, shimmer percent, and noise to harmonic ratio had significant differences between the pre-and post-treatment(p< .05). As the respiration and the oral motor improved MPT, voice quality, and articulation of vowel, and the variation of the formant(F1, F2, F3) showed the changes in the shape of lips, the place and the height of the tongue, the various development of therapy programs and the consistent intervention of treatment is needed for the children with cerebral palsy.

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한국(韓國)의 의료기사(醫療技士) 교육제도(敎育制度)에 관(關)한 조사(調査) 연구(硏究) (A Study of Educational System for Medical Technologists in Korea)

  • 송재관;이건섭;김병락;김정락;조준석;허준;이준일
    • 대한방사선기술학회지:방사선기술과학
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    • 제6권1호
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    • pp.131-181
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    • 1983
  • After the investigation on, and the analysis of, the educational system for medical technicians and the present educational situation for medical technologies in this country, the following conclusions were drawn. 1. As of March 1983 the current academic system for education in medical technologies included the regular 4-year college courses and those of the 2-year professional junior college courses. But except in the cases on clinical pathology and physical therapy, there were no college-level departments. Particularly, no educational institutions, at whatever level, had a department for working therapies. 2. The total number of credits needed for graduation from a department of medical technologies was 150 points at a regular 4-year college and 85 to 96 points at a 2-year professional college. The obligatory minimum number of credits for a student at a professional college was set at 80 points and above. 3. As for the number of the educational institutions for medical technologies in this country, there were one regular college and 14 professional colleges, a total of 15 institutions. As many as 14 colleges had departments of clinical pathology, 12 had departments of Radiotechnology, 11 had departments of physical therapy, 12 had departments of dental technology, and eight had departments of dental hygiene. 4. The total capacity of the professional colleges in admitting new enrollment each year were 1,920 for clinical pathology, 1,552 for radiology, 1,012 for physical therapy, 1,334 for dental technologies, 828 for dental hygiene, an aggregate of 6,646 for all of the professional college departments. 5. The total number of graduates from the 12 professional colleges by department during the period of 1965-83 were 7,595 for clindical pathology, 4,768 for radiology, 2,821 for physical therapy, 3,000 for dental technologies, and 1,787 for dental hygiene, totalling 19,971 for all departments in the professional colleges. 6. In the state examination for licensed medical technicians, 12,446 have passed from among the total of 26,609 participants, representing a 45% passing ratio. By departments the ratios showed 44% for clinical pathology, 39.7% for radiology, 51.2% for physical therapy, 42.5% for dental technology, 72.5% for dental hygiene and 73.1% for working therapy. 7. As for the degree of satisfaction shown by the people in this field, 52.2 percent of the teaching staffs who responed to the questionaires said they were satisfied with their present profession, while the great majority of medical technicians(66%) replied that they were indifferent to the problem. 8. The degree of satisfaction shown by the students on their enrollment in this particular academic field was generally in the framework of indifference(43.7%), but mere students(36.5%) were satisfied with their choice than those were not satisfied(14.4%) 9. As for the student's opinions on the lectures and practicing hours, a good many students replied that, among such courses as general science and humanities courses the basic medical course, the major course and practicing hours, the hours provided for the general courses(47.1%) and practicing(47.6%) were insufficient. 10. When asked about the contents of their major courses, comparatively few students (23.6%) replied that the courses were too difficult, while a convincing majority(58.5%) said they were neither difficult nor easy. As for the appropriateness of the number of the present teaching staffs, a great majority(71.0%) of the students replied that the level of the teaching personnel in each particular field was insufficient. 11. Among the students who responded to the poll, good part of them(49.5%) wanted mandatory clinical practicing hours, and the the majority of them(64.6%) held the view that the experimental and practicing facilities of their schools were insufficient. 12. On the necessity of the attached hospitals, 71.1% of the teaching staffs and 58.0% of the medical technicians had the opinion that this kind of facility was indispensable. 13. As for the qualifications for applicants to the state examination in the licensing system for medical technicians, 52.2% of the teacher's and 36% of the medical technicians replied that the present system granting the qualifications according to the apprenticeship period should be abolished. 14. On the necessity of improving the present system for education in medical technologies, an overwhelming majority(94.4% of the :caching staffs, 92.0% of the medical technicians and 91.9% of students) of these polled replied that the present system should be changed for the better. 15. On the method of changes for the present educational system, a great majority(89.4% of the teaching staffs, 80.4% of the medical technicians and 90.1% of the students) said that the system must be changed so that it fits into the reality of the present day. 16. As for the present 2-year program for the professional colleges, 61.6% of the teachers, 72.0% of the medical technicians and 38.8% of the students expressed the hope that the academic period would be extended to four regular years, hemming a full-fledged collegelevels program. 17. On the life-long eductional system for medical technicians, there was a considerable number of people who expressed the hope that an open university system(38.9% of the teaching staffs, 36.0% of the medical technicians) and a graduate school system would be set up. 18. As for the future prospects for medical technicians as professionals, the optimists ana pessimists were almost equally divided, and 41.1% of the teaching staffs 36.0% of. the technicians and 50.5% of the students expressed an intermediate position on this issue.

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