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Development of a Small Gamma Camera Using NaI(T1)-Position Sensitive Photomultiplier Tube for Breast Imaging (NaI (T1) 섬광결정과 위치민감형 광전자증배관을 이용한 유방암 진단용 소형 감마카메라 개발)

  • Kim, Jong-Ho;Choi, Yong;Kwon, Hong-Seong;Kim, Hee-Joung;Kim, Sang-Eun;Choe, Yearn-Seong;Lee, Kyung-Han;Kim, Moon-Hae;Joo, Koan-Sik;Kim, Byuug-Tae
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.4
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    • pp.365-373
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    • 1998
  • Purpose: The conventional gamma camera is not ideal for scintimammography because of its large detector size (${\sim}500mm$ in width) causing high cost and low image quality. We are developing a small gamma camera dedicated for breast imaging. Materials and Methods: The small gamma camera system consists of a NaI (T1) crystal ($60 mm{\times}60 mm{\times}6 mm$) coupled with a Hamamatsu R3941 Position Sensitive Photomultiplier Tube (PSPMT), a resister chain circuit, preamplifiers, nuclear instrument modules, an analog to digital converter and a personal computer for control and display. The PSPMT was read out using a standard resistive charge division which multiplexes the 34 cross wire anode channels into 4 signals ($X^+,\;X^-,\;Y^+,\;Y^-$). Those signals were individually amplified by four preamplifiers and then, shaped and amplified by amplifiers. The signals were discriminated ana digitized via triggering signal and used to localize the position of an event by applying the Anger logic. Results: The intrinsic sensitivity of the system was approximately 8,000 counts/sec/${\mu}Ci$. High quality flood and hole mask images were obtained. Breast phantom containing $2{\sim}7 mm$ diameter spheres was successfully imaged with a parallel hole collimator The image displayed accurate size and activity distribution over the imaging field of view Conclusion: We have succesfully developed a small gamma camera using NaI(T1)-PSPMT and nuclear Instrument modules. The small gamma camera developed in this study might improve the diagnostic accuracy of scintimammography by optimally imaging the breast.

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Use of Unmanned Aerial Vehicle for Forecasting Pine Wood Nematode in Boundary Area: A Case Study of Sejong Metropolitan Autonomous City (무인항공기를 이용한 소나무재선충병 선단지 예찰 기법: 세종특별자치시를 중심으로)

  • Kim, Myeong-Jun;Bang, Hong-Seok;Lee, Joon-Woo
    • Journal of Korean Society of Forest Science
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    • v.106 no.1
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    • pp.100-109
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    • 2017
  • This study was conducted for preliminary survey and management support for Pine Wood Nematode (PWN) suppression. We took areal photographs of 6 areas for a total of 2,284 ha during 2 weeks period from 15/02/2016, and produced 6 ortho-images with a high resolution of 12 cm GSD (Ground Sample Distance). Initially we classified 423 trees suspected for PWN infection based on the ortho-images. However, low accuracy was observed due to the problems of seasonal characteristics of aerial photographing and variation of forest stands. Therefore, we narrowed down 231 trees out of the 423 trees based on the initial classification, snap photos, and flight information; produced thematic maps; conducted field survey using GNSS; and detected 23 trees for PWN infection that was confirmed by ground sampling and laboratory analysis. The infected trees consisted of 14 broad-leaf trees, 5 pine trees (2 Pinus rigida), and 4 other conifers, showing PWN infection occurred regardless of tree species. It took 6 days for 2.3 men from to start taking areal photos using UAV (Unmanned Aerial Vehicle) to finish detecting PNW (Pine Wood Nematode) infected tress for over 2,200 ha, indicating relatively high efficacy.

Performance Characteristics of MicroPET R4 Scanner for Small Animal Imaging (소동물 영상을 위한 MicroPET R4스캐너의 특성평가)

  • Lee, Byeong-Il;Lee, Jae-Sung;Kim, Jin-Su;Lee, Dong-Soo;Choi, Chang-Un;Lim, Sang-Moo
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.1
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    • pp.49-56
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    • 2005
  • Purpose: Dedicated animal PET is useful equipment for the study of new PET tracer. recently, microPET R4 was installed in the Korea institute of radiology and medical science. In this study, we measured the characteristics of scanner. Materials and methods: Resolution was measured using a line source (F-18:65 ${\mu}Ci$, inner diameter: 0.5 mm). The line source was put in the axial direction and was moved from the center of field of view to outside with 1 mm interval. PET images were reconstructed using a filtered back-protection and ordered subset expectation maximization. line source (16.5 ${\mu}Ci$, 78 mm) was put on the tenter of axial direction to measure the sensitivity when the deadtime was under 1%. Images were acquired during 4 minutes respectively from center to 39 mm outward. Delayed count was subtracted from total count and then decay was corrected for the calculation of sensitivity. Noise equivalent count ratio and scatter fraction were calculated using cylindrical phantom. Results: Spatial resolution of reconstructed image using filtered back-projection was 1.86 mm(radial), 1.95 mm(tangential), 1.95 mm(axial) in the tenter of field of view, and 2.54 mm, 2.8 mm, 1.61 mm in 2 cm away from the center respectively. Sensitivity was 2.36% at the center of transaxial field of view. Scatter fraction was 20%. Maximal noise equivalent count ratio was 66.4 kcps at 242 kBq/mL. Small animal images were acquired for confirmation of performance. Conclusion: Performance characteristics of microPET R4 were similar with reported value. So this will be a useful tool for small animal imaging.

Functional MRI of Visual cortex in the Patients with Occipital Lobe Ischemia (후두엽의 허혈성 뇌졸중 환자에서 시각피질의 기능적 자기공명영상)

  • 이영준;정태섭;윤영수;한승한;조영재;배준호
    • Investigative Magnetic Resonance Imaging
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    • v.3 no.2
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    • pp.173-178
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    • 1999
  • Purpose : To evaluate the usefulness of functional MRI (fMRI) of visual cortex in patients with ischemic infarction in the occipital lobe. Materials and Methods : Four patients with the symptoms and signs of visual cortical ischemia were included. Functional MRI was performed by 2D-FLASH technique with the parameter of 90/56msec TR/TE, $40^{\circ}$ flip angle, $240{\times}240{\;}FOV,{\;}64{\times}128$ matrix number, 8.32 seconds acquisition time, 8mm slice thickness. An axial slice including both visual cortices was selected and alternative activation and resting of the visual cortex was performed using red color photostimulator. all patients undertook visual field test, and vascular abnormality was examined by MRA (n=4) and DSA (n=2). fMRI results were compared with the results of a visual field test, conventional MRI and cerebral angiography. Results : On fMRI, decreased activity of the visual cortex was found in the occipital lobe corresponding to stenosis of the posterior cerebral artery or its branch noted on angiogram. However, 2 of 4 patients showed no abnormal findings on conventional MRI. Visual field defect was noted in 3 patients, one and of whom showed no abnormality on conventional MRI and diffusion-weighted image, but revealed decreased activity in the corresponding visual cortex on fMRI. Conclusion : fMRI may be a sensitive method for detection of the status of decreased blood flow or vascular reserve which other methods can not.

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감마나이프 방사선치료에서 소프트웨어와 하드웨어 시간설정차이에 의한 처방선량에 주는 영향

  • 서원섭;임영진;신동오
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.60-60
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    • 2003
  • 목적 : 감마나이프 치료계획용 소프트웨어인 감마플렌에서 처방선량을 계산하는 단위와 실제 시간을 설정하는 하드웨어인 조정판의 시간설정 단위의 차이에 의한 실제 처방선량에 끼치는 영향을 계산하였다. 대상 및 방법 : 감마나이프는 주어진 4 개의 헬멧을 가지고 최소 한번 또는 최대 20 번 이상의 방사선 조합으로 한번에 많은 방사선을 목표물에 조사한다. 감마나이프 방사선 수술을 위한 치료계획용 소프트웨어인 감마플렌 5.32에서는 처방선량에 대한 치료시간을 최대 지점 또는 지정하는 지점에 규격화하여 소숫점 두 자리 즉 0.6 초까지 계산한다. 그러나 실제 치료를 위한 조정판의 시간설정은 모델 B 에서는 소숫점 한자리까지 가능하게 되어있다. 그러므로 모델 B를 사용하는 기관의 치료계획 컴퓨터인 감마플렌에서는 소숫점 한자리로 만들기 위해 반올림과 내림을 하게 되며 이것을 프린트하여 사용하게 된다. 실제 임상에서 멀티삿에 대한 반올림과 내림에 대한 효과를 선량으로 환산하여 처방선량에 끼치는 영향을 연구하였다. 치료 계획에 서 처방선량을 입력한 후 계산된 각 조사에 대한 소숫점 두자리 시간을 화면에 표시한 후 스냅tit으로 스크린 캡쳐하여 프린트하였으며, 소숫점 한자리로 된 최종 치료계획을 프린트하여 서로 비교 계산하였다. 결과 : 20 여명의 환자에 대한 치료 결과에 대한 분석은 조사의 수나 처방선량에 관계하지 않고 우연히 올림이 많으냐 내림이 많으냐에 의존하였다. 최대지점에 대하여 분석한 결과는 -0.48부터 +0.47로 -2%부터 +1.9%의 정도로 영향을 끼쳤다. 결론 : 반올림과 내림의 결과는 처방선량을 줄일 수도 있고 늘일 수도 있었다. 그러나 이 연구는 최대선량 지점에 대해 비교를 하였으나 실제로는 각 조사의 위치가 서로 다르므로 영향은 이보다 훨씬 적을 것으로 생각되어 소숫점 한자리로 치료하여도 무방할 것으로 보인다.mm, AP 방향에서는 2.1$\pm$0.82 mm이었다. 그리고 복부의 later의 방향에서는 7.0$\pm$2.1 mm, AP 방향에서는 6.5$\pm$2.2 mm 이었다. 또한 표적 위치측정을 위해서 환자의 피부에 임의의 가상표적을 부착하고 CT 촬영한 영상결과, 프레임으로 가상표 적에 대한 위치를 정확히 파악할 수 있었다. 결론 : 제작된 프레임을 적용하여 방사선투과율 측정실험, 환자 외부자세에 대한 오차 측정실험, 가상표적 위치측정 실험 등을 수행하였다. 환자 외부자세에 대한 오차 측정실험 경우, 더 많은 Volunteer를 적용하여 보다 정확한 오차 측정실험이 수행되어야 할 것이며 정확한 표적 위치 측정실험을 위해서 내부 마커를 삽입한 환자를 적용한 임상실험이 수행되어야 할 것이다. 또한 위치결정에서 획득한 좌표값의 정확성을 알아보기 위해서 팬톰을 이용한 방사선조사 실험이 추후에 실행되어져야 할 것이다. 그리고 제작된 프레임에 Rotating X선 시스템과 내부 장기의 움직임을 계량화하고 PTV에서의 최적 여유폭을 설정함으로써 정위 방사선수술 및 3 차원 업체 방사선치료에 대한 병소 위치측정과 환자의 자세에 대한 setup 오차측정 결정에 도움이 될 수 있을 것이라고 사료된다. 상대적으로 우수한 것으로 나타났으며, 혼합충전재는 암모니아의 경우 코코넛과 펄라이트의 비율이 7:3인 혼합 재료 3번과 소나무수피와 펄라이트의 비율이 7:3인 혼합 재료 6번에서 다른 혼합 재료에 비하여 우수한 것으로 나타났다. 4. 코코넛과 소나무수피의 경우 암모니아 가스에 대한 흡착 능력은 거의 비슷한 것으로 사료되며, 코코넛의 경우 전량을 수입에 의존하고 있다는 점에서 국내 조달이 용이하며, 구입 비용도 적게 소요되는 소나무수피를 사용하는 것이 경제적이라고 사료된다. 5. 마지막으로

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Study on establishment of a governance for agricultural NPS pollution management (농업비점오염 관리를 위한 참여단위 거버넌스 구축 연구)

  • Jang, Jeong Ryeol;Um, Han Yong;Park, Hyeong Min;Jo, Young Ju
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.29-29
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    • 2016
  • 새만금호의 목표수질 달성과 지속가능한 관리를 위해서는 비점오염 관리의 필요성이 강조되고 있다. 특히, 새만금호 상류 유역은 농경지 비율이 38%로서 높아 농업활동에서 유래하는 농업 비점오염원의 효과적인 관리가 필요하다. 이를 위해서는 농업비점오염 저감기술의 개발하는 물리적 기술적 접근만이 아니라 농업인과 지역주민의 참여와 함께 행정적인 지원을 포함하는 사회 경제 문화적 접근을 포함하는 통합적인 접근 즉, 거버넌스가 요구된다. 이러한 거버넌스를 새만금유역의 농업비점 관리에 적용하려는 노력의 일환으로 "새만금유역 농업비점오염관리 거버넌스구축 사업모델 개발"에 대한 연구를 2015년부터 2016년까지 2년간 추진하게 되었다. 본 연구의 목적은 농업비점오염 관리를 위한 거버넌스 구축과 운영에 필요한 요소들을 도출하고 각각의 요소별 추진 프로세스를 개발하고 최종적으로 이를 상호 연계하여 운영하는 기법을 개발하는 것이다. 농업비점오염관리 거버넌스 구축의 접근 방향으로는 신규구축형과 기존정책사업연계형으로 접근하는 것이 바람직 할 것으로 판단된다. 거버넌스 시스템은 참여단위와 행정단위, 그리고 이것을 연계 지원하는 '중간지원조직'의 다층적 거버넌스 구조로 제안하였다. 참여단위 거버넌스는 공동체단위와 개별 농가단위의 참여 프로그램으로 설계하였다. 특히, 참여단위 거버넌스의 지속성을 유지하기 위해서 커뮤니티비즈니스 육성이 필요할 것으로 나타났다. 1차년도(2015년)에는 신규구축형을 중심으로 진행을 위하여 전라북도 부안군 백산면 용계리를 연구대상 지구로 선정하였다. 참여단위 거버넌스 구축을 위하여 연구대상 지구에서 우리 마을과 물 이야기, 우리마을회의 등 통하여 주민이 생각하는 지역의 역사와 문화 등 잠재자원을 발굴하였고, 이를 바탕으로 침체된 마을 공동체를 마을길을 연결하여 다시 활성화 하고, 물이 흐르는 마을도랑으로 가꾸고, 단절된 이웃간 마음을 연결하기 위한 "마을길-물길-마음길 연결" 커뮤니티 비즈니스 프로젝터를 도출하였다. 이러한 거버넌스구축 프로그램의 정보의 공유와 확산을 위하여 커뮤니티 비즈니스 안내판을 설치하고, 마을소식지(청파)를 제작배부하고 거버넌스구축 과정을 담은 마을영상다큐 제작을 진행하였다. 2차년도에는 커뮤니티 비즈니스 심화과정을 운영하고자 한다. 본 연구의 결과는 앞으로 농촌지역의 비점오염관리를 위한 거버넌스구축 등 정책 및 제도개선에 도움이 될 것으로 기대된다.

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A Study on Multi-resolution Screen based Conference Broadcasting Technology (멀티 해상도 스크린 기반의 컨퍼런스 중계방송 기술 연구)

  • Kim, Young-ae;Yang, Ji-hee;Park, Goo-man
    • Journal of Broadcast Engineering
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    • v.23 no.2
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    • pp.253-260
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    • 2018
  • Personalized media broadcasting services can produce their own broadcasting contents with a variety of creative themes if they have just a transmission platform and devices that can obtain videos and voices of producers without the existing expensive equipment. In this paper, we develop and implement a new broadcasting system by applying this service framework to events such as seminars or academic conferences. The devices can be installed at each conference rooms and the integrated system transmitted to users. They can watch via their multi-resolution screen, such as smart-phones, laptops, and tablet PCs. It has the advantage of being able to receive real-time streaming and VOD services as well as additional information related to the conference. It is expected to provide convenience by allowing attendees to access the information via their devices, thereby creating an impact on participation and the underlying technology for the future research.

The Comparison of Image Quality and Quantitative Indices by Wide Beam Reconstruction Method and Filtered Back Projection Method in Tl-201 Myocardial Perfusion SPECT (Tl-201 심근관류 SPECT 검사에서 광대역 재구성(Wide Beam Reconstruction: WBR) 방법과 여과 후 역투영법에 따른 영상의 질 및 정량적 지표 값 비교)

  • Yoon, Soon-Sang;Nam, Ki-Pyo;Shim, Dong-Oh;Kim, Dong-Seok
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.2
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    • pp.122-127
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    • 2010
  • Purpose: The Xpress3.$cardiac^{TM}$ which is a kind of wide beam reconstruction (WBR) method developed by UltraSPECT (Haifa, Israel) enables the acquisition of at quarter time while maintaining image quality. The purpose of this study is to investigate the usefulness of WBR method for decreasing scan times and to compare to it with filtered back projection (FBP), which is the method routinely used. Materials and Methods: Phantom and clinical studies were performed. The anthropomorphic torso phantom was made on an equality with counts from patient's body. The Tl-201 concentrations in the compartments were 74 kBq (2 ${\mu}Ci$)/cc in myocardium, 11.1 kBq (0.3 ${\mu}Ci$)/cc in soft tissue, and 2.59 kBq (0.07 ${\mu}Ci$)/cc in lung. The non-gated Tl-201 myocardial perfusion SPECT data were acquired with the phantom. The former study was scanned for 50 seconds per frame with FBP method, and the latter study was acquired for 13 seconds per frame with WBR method. Using the Xeleris ver. 2.0551, full width at half maximum (FWHM) and average image contrast were compared. In clinical studies, we analyzed the 30 patients who were examined by Tl-201 gated myocardial perfusion SPECT in department of nuclear medicine at Asan Medical Center from January to April 2010. The patients were imaged at full time (50 second per frame) with FBP algorithm and again quarter-time (13 second per frame) with the WBR algorithm. Using the 4D MSPECT (4DM), Quantitative Perfusion SPECT (QPS), and Quantitative Gated SPECT (QGS) software, the summed stress score (SSS), summed rest score (SRS), summed difference score, end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were analyzed for their correlations and statistical comparison by paired t-test. Results: As a result of the phantom study, the WBR method improved FWHM more than about 30% compared with FBP method (WBR data 5.47 mm, FBP data 7.07 mm). And the WBR method's average image contrast was also higher than FBP method's. However, in result of quantitative indices, SSS, SDS, SRS, EDV, ESV, EF, there were statistically significant differences from WBR and FBP(p<0.01). In the correlation of SSS, SDS, SRS, there were significant differences for WBR and FBP (0.18, 0.34, 0.08). But EDV, ESV, EF showed good correlation with WBR and FBP (0.88, 0.89, 0.71). Conclusion: From phantom study results, we confirmed that the WBR method reduces an acquisition time while improving an image quality compared with FBP method. However, we should consider significant differences in quantitative indices. And it needs to take an evaluation test to apply clinical study to find a cause of differences out between phantom and clinical results.

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The Study on the Attenuation of X-ray and Imaging Quality by Contents in Stomach (위장내 음식물에 따른 방사선 감약 및 화질에 관한 연구)

  • Dong, Kyung-Rae;Ji, Youn-Sang;Kim, Chang-Bok;Choi, Seong-Kwan;Moon, Sang-In;Dieter, Kevin
    • Journal of radiological science and technology
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    • v.32 no.1
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    • pp.53-60
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    • 2009
  • This study examined the change in the attenuation of X-rays with the ROI (Region of Interest) in DR (Digital Radiography) according to the stomach contents by manufacturing a tissue equivalent material phantom to simulate real stomach tissue based on the assumption that there is some attenuation of X-rays and a difference in imaging quality according to the stomach contents. The transit dosage by the attenuation of X-rays decreased with increasing protein thickness, which altered the average ROI values in the film and DR images. A comparison of the change in average ROI values of the film and DR image showed that the image in film caused larger density changes with varying thickness of protein than the image by DR. The results indicate that NPO (nothing by mouth) is more important in film system than in DR system.

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A CT Simulator Phantom for Geometrica1 Test (CT 시뮬레이터의 기하학적 성능평가용 팬톰)

  • Min, Chul-Kee;Yi, Byong-Yong;Ahn, Seung-Do;Choi, Eun-Kyung;Chang, Hye-Sook
    • Radiation Oncology Journal
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    • v.18 no.4
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    • pp.337-344
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    • 2000
  • Purpose :To design and test test CT simulator phantom for geometrical test. Materials and Methods : The PMMA phantom was designed as a cylinder which is 20 cm in diameter and 24 cm in length, along with a 25$\times25\times31cm^{3}$ rectangular parallelepiped. Radio-opaque wires of which diameter is 0.8 mm are attached on the other surface of the phantom as a spiral. The rectangular phantom was made of four 24$\times24\times0.5 cm^{3}$ square plates and each plate had a 24$\times24 cm^{2}$, 12$\times12cm^{2}$, 6$\times6 cm$^{2}$ square line. The squares were placed to face the cylinder at angles 0 $^{\circ}$ , 15 $^{\circ}$ , 30 $^{\circ}$ ,respectively. The rectangular phantom made it possible to measure the field size, couch angle, the collimator angle, the isocenter shift and the SSD, the measurements of the gantry angle from the cylindrical part. A virtual simulation software, AcOSim, offered various conditions to perform virtual simulations and these results were used to perform the geometrical Quality assurance of CT simulator. Results : A 0.3$\~$0.5 mm difference was found on the 24 cm field size which was created with the DRR measurements obtained by scanning of the rectangular phantom. The isocenter shift, the collimator rotation, the couch rotation, and the gantry rotation test showed 0.5$\~$1 mm, 0.5$\~$l$^{\circ}$ 0.5$\~$ 1$^{\circ}$ , and 0.5-1 $^{\circ}$ differences, respectively. We could not find any significant differences between the results from the two scanning methods. Conclusion :The geometrical test phantom developed in the study showed less than 1 mm (or 1 $^{\circ}$ ) differences. The phantom could be used as a routine geometrical QC/QA tools, since the differences are within clinically acceptable ranges.

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