• Title/Summary/Keyword: 1,3,5-Triketones

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Synthesis of 1H-Indol-3-ylpyrazole Derivatives from 1,3,5-Triketones and Arylhydrazines: One-Pot Construction of Pyrazole and Indole Rings

  • Kim, Sung Hwan;Lee, Sangku;Kim, Se Hee;Kim, Ko Hoon;Kim, Jae Nyoung
    • Bulletin of the Korean Chemical Society
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    • v.34 no.11
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    • pp.3415-3419
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    • 2013
  • The reaction of 1,3,5-triketones and arylhydrazines provided indolylpyrazole derivatives in a one-pot reaction in good to moderate yields. Both the pyrazole and indole rings were constructed simultaneously with phenylhydrazine, $RCOCH_2CO$- moiety for the pyrazole and the remaining -$CH_2COR$ part for the indole ring.

Synthesis of 2,5Bis(2'-piperidymethyl)piperidine and Related Compounds

  • Hammouda, Metwally;Kandeel, Ex-el-Din;Hamama, Wafaa;Afsah, Elsayed
    • Archives of Pharmacal Research
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    • v.16 no.1
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    • pp.68-70
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    • 1993
  • The triketones 3-6 were obtained by alkylation of cyclopentanone or cyclohexanone with the appropriate cycloalkanone bis-mannich base (1) or (2). Schmidt reaction of the tricketones 3-6 afforded the corresponding trcyclic lactames 7-10 respectively. reduction of 7 and 9 gave compounds 11 and 12 respectively.

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