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http://dx.doi.org/10.5012/bkcs.2013.34.11.3415

Synthesis of 1H-Indol-3-ylpyrazole Derivatives from 1,3,5-Triketones and Arylhydrazines: One-Pot Construction of Pyrazole and Indole Rings  

Kim, Sung Hwan (Department of Chemistry and Institute of Basic Science, Chonnam National University)
Lee, Sangku (Immune Modulator Research Center, KRIBB)
Kim, Se Hee (Department of Chemistry and Institute of Basic Science, Chonnam National University)
Kim, Ko Hoon (Department of Chemistry and Institute of Basic Science, Chonnam National University)
Kim, Jae Nyoung (Department of Chemistry and Institute of Basic Science, Chonnam National University)
Publication Information
Bulletin of the Korean Chemical Society / v.34, no.11, 2013 , pp. 3415-3419 More about this Journal
Abstract
The reaction of 1,3,5-triketones and arylhydrazines provided indolylpyrazole derivatives in a one-pot reaction in good to moderate yields. Both the pyrazole and indole rings were constructed simultaneously with phenylhydrazine, $RCOCH_2CO$- moiety for the pyrazole and the remaining -$CH_2COR$ part for the indole ring.
Keywords
Indolylpyrazole; 1,3,5-Triketones; Fischer indole synthesis;
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