• Journal of Microbiology and Biotechnology
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• 제25권7호
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• pp.1146-1153
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• 2015

This study was conducted to assess the relationship between occurrence of gastric cancer and peptic ulcer, and the presence of H. pylori cagA gene and anti-CagA IgG, and to estimate the value of these antibodies in detecting infection by cagA gene-positive H. pylori strains in Saudi patients. The study included 180 patients who were subjected to upper gastrointestinal endoscopy in Taif province and Western region of Saudi Arabia (60 gastric cancer, 60 peptic ulcer, and 60 with non-ulcer dyspepsia). Gastric biopsy specimens were obtained and tested for H. pylori infection by rapid urease test and culture. PCR was performed on the isolated strains and biopsy specimens for detection of the cagA gene. Blood samples were collected and tested for CagA IgG by ELISA. H. pylori infection was detected among 72.8% of patients. The cagA gene and anti-CagA IgG were found in 63.4% and 61.8% of H. pylori-infected patients, respectively. They were significantly (p < 0.01) higher in patients with gastric cancer and peptic ulcer compared with those with non-ulcer dyspepsia. Detection of the CagA IgG was 91.6% sensitive, 89.6% specific, and 90.8% accurate compared with detection of the cagA gene. Its positive and negative predictive values were 93.8% and 86%, respectively. The study showed a significant association between the presence of the cagA gene and gastric cancer and peptic ulcer disease, and between anti-CagA IgG and the cagA gene in Saudi patients. However, a further larger study is required to confirm this finding.

• 한국임상수의학회지
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• 제20권1호
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• pp.33-41
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• 2003

건강한 잡종견(4.16$\pm$0.65kg, mean$\pm$SD) 15두를 tiletamine/zolazepam(TZ) 투여군(대조군), xylazine-tiletamine/zolazepam(XTZ) 투여군 및 medetomidine -tiletamine/ zolazepam(MTZ) 투여군으로 구분하고 마취 효과와 심폐계 영향을 평가하였다. Atropine(0.03mg/kg, IM) 투여 10분 후 xylazine(1.1mg/kg IM) 또는 medetomidine(30ug/kg, IM)투여 10분 후 xylazine(1.1mg/kg IM) 또는 medetomidine (30mg/kg IM)을 투여하였으며, atropine투여 20분 후에 TZ(10mg/kg IV)를 해당 실험군에 투여하였다. Pedal reflex와 ear pinching test 시 TZ군과 비교하여 XTZ군과 MTZ군에서 통증반응의 소실이 유의성 있게 증가하였다.(P<0.05) TZ 투여 직후부터 실험견이 머리를 들기까지 걸리는 평균시간과 실험견이 흉와 자세를 유지하기까지 걸리는 평균 시간, 실험견이 완전히 걸을 수 있을 때까지의 소요시간 역시 TZ군에 비해 XTZ군과 MTZ군에서 유의적인 증가를 나타내었다. (P<0.01) 본 실험에 사용된 모든 실험견은 회복기에 머리를 심하게 흔들고, 과도한 유연을 나타내었다. 체온은 전 실험군에서 점차 감소하였으나, 유의성은 나타나지 않았다. 대조군에서 심박수는 TZ투여 후 10분과 20분에서 유의성 있게 증가하였으며, XTZ군에서는 유의성 있는 변화가 관찰되지 않았다. 호흡수는 XTZ군과 MTZ군에서 xylazine 또는 medetomidine투여 후 10분, TZ 투여 후 10, 20, 40분에 유의성 있는 감소가 나타났다. 대조군에서는 TZ 투여 10분 후의 이완기 혈압, 20분후의 수축기 혈압, 그리고 10분과 20분 후의 평균혈압이 유의성 있게 감소하였다.(P<0.05) XTZ군에서는 모든 혈압이 TZ투여 후 20분과 40분에서 유의성 있게 감소하였다. (P<0.05) 본 실험 결과, XTZ와 MTZ의 병용은 개에서 강한 진통작용과 긴 마취시간을 필요로 하는 외과 처치시 유용한 마취조합으로 사료된다.

• Journal of Dairy Science and Biotechnology
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• 제26권1호
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• pp.1-4
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• 2008

본 연구는 숙면 유도 호르몬으로 알려진 멜라토닌의 원유 및 유제품 내 함량을 방사면역측정법으로 분석하였으며, 그 결과는 다음과 같다. 1. 착유 시간에 따른 멜라토닌 함량은 새벽 4시에 착유한 원유 샘플의 멜라토닌 함량이 평균 $6.90{\pm}3.55pg/mL$로 나타났으며, 저녁 7시 및 낮 12시 착유 원유 샘플은 각각 $2.01{\pm}1.47pg/mL$와 $0.16{\pm}0.04pg/mL$로 나타나 새벽 착유 원유 내 멜라토닌 함량이 유의적으로 높은 결과를 나타내었으며, 이는 로봇 착유기를 사용하는 농가에서도 심야 및 새벽 착유 원유에서 멜라토닌 함량이 가장 높게 나타나 2개 목장 모두 비슷한 결과를 나타내었다. 2. 일반 우유 제품과 나이트 밀크 제품 간 멜라토닌 함량비교 시, 나이트 밀크의 멜라토닌 함량이 약 5배 정도 높은 결과를 보였다. 3. 일반 우유를 대상으로 원유, 균질 및 살균 등의 공정이 멜라토닌 함량에 영향을 미치지 않는 것으로 나타났으나, 그 수준은 매우 낮은 농도로 존재하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3645-3651
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• 2015

Background: Previous studies evaluating the association between the xeroderma pigmentosum group G (XPG) Asp1104His polymorphism and head and neck cancer susceptibility have proven controversial. This meta-analysis of the literature was performed to obtain a more precise estimation of the relationship. Materials and Methods: We systematically searched PubMed, Embase and Web of Science with a time limit of Dec 18, 2014. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of any association. Results: We performed a meta-analysis of eight published case-control studies, including 3,621 cases and 5,475 controls. Overall, no significant association was found between the XPG Asp1104His polymorphism and head and neck cancer susceptibility under all genetic models. In the subgroup analysis by ethnicity, the XPG Asp1104His polymorphism had statistically significant association with elevated head and neck cancer risk under CC vs GG (OR=1.24, 95% CI=1.00~1.54) and the recessive model (OR=1.22, 95%CI=1.01~1.46) in Asian populations. A similar result was found under CC vs GG (OR =1.22, 95%CI=1.01~1.47) in the population based subgroup by source of control. When performed by tumor site, the XPG Asp1104His polymorphism had statistically significant association with elevated laryngeal cancer under all genetic models (CC vs GG: OR=1.59, 95% CI=1.16~2.19; GC vs GG: OR=1.38, 95%CI=1.10~1.72; dominant model: OR=1.42, 95% CI=1.15~1.74; recessive model: OR=1.36, 95% CI=1.02~1.81). Conclusions: This meta-analysis suggested that the XPG Asp1104His polymorphism is a risk factor for head and neck cancer susceptibility, especially for laryngeal cancer and in Asian populations.

• 한국식품영양과학회지
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• 제42권6호
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• pp.904-910
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• 2013

본 연구는 젊은 성인을 대상으로 운동 목적에 따른 영양섭취 실태를 조사하고자 수행되었다. 규칙적으로 운동하고 있는 20~30대 남녀를 대상으로 운동 목적에 따라 근육증가군 107명과 체중감소군 107명을 나누어 비교 분석하였다. 그룹별 성별구성을 분석한 결과, 근육증가군은 주로 남성(75.2%)이 많은 반면 체중감소군은 여성(74.3%)이 많이 분포하고 있었다. BMI 판정결과 두 그룹간의 유의적인 차이는 없었으며, 체중감소군의 절반 이상(56%)이 저체중 또는 정상체중으로 나타났다. 근육증가군의 하루 운동시간 및 규칙적으로 운동한 기간이 체중감소군에 비하여 유의적으로 많았다(p<0.01). 영양지식의 상태는 근육증가군의 점수가 체중 감소군에 비하여 유의적으로 높은 것으로 나타났다(p<0.05). 식행동 또한 근육량 증가군의 점수가 체중감소군에 비하여 유의적으로 높았다(p<0.05). 영양섭취 상태를 살펴보면, 한국인영양섭취기준과 비교하였을 때 근육증가군의 에너지 섭취비율이 에너지필요추정량의 83.72%로 체중감소군의 74.53%에 비하여 유의적로 높았다(p<0.01). 권장섭취량에 대한 단백질 섭취비율은 근육증가군이 199.62%, 체중감소군은 136.36%로 나타났으며 근육증가군이 체중감소군에 비해 유의적으로 매우 많은 양을 섭취하고 있었다(p<0.001). 권장섭취량에 대한 칼슘 섭취비율은 근육증가군이 67.75%, 체중감소군은 68.64%로 조사되었으며, 두 군 모두 권장섭취량과 비교하여 매우 부족한 수준으로 나타났다. 이와 같이 본 연구에서는 근육증가를 목적으로 운동하는 경우 과량의 단백질을 섭취하고 있었으며, 체중감소를 목적으로 운동하는 경우 필요량에 미치지 못하는 에너지 섭취를 하는 것으로 나타났다.

• Asian-Australasian Journal of Animal Sciences
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• 제22권2호
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• pp.225-231
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• 2009

The objective of this experiment was to study the effects of grass maturity at harvest on the nutritive value of grass silage (GS) in relation to voluntary intake, digestibility, nitrogen (N) utilization and in sacco dry matter (DM) degradability. Silage was cut from a sward dominated by orchardgrass (Dactylis glomerata L.) at the late-vegetative (early-cut), internode elongation (mediumcut) and flowering (late-cut) stages of growth. The DM yield at harvest was the lowest for early-cut silage (5.4 t/ha) and increased to 6.5 and 7.0 t/ha for the medium and late-cut silage respectively. As the crop matured, the crude protein (CP) concentration decreased significantly (p<0.05) and there was a marked increase in acid detergent fiber (ADF) concentration (p<0.001). The three different silages were offered to four 18-month old Charolais wether sheep to measure the voluntary intake, in vivo digestibility and N retention over four 21-day periods in an incomplete changeover design. Silage degradability characteristics were determined using four fistulated sheep to measure DM degradability over 3, 6, 12, 24, 48 and 72 h. There was a linear decrease in the voluntary intake of silage fresh matter, DM, organic matter (OM) and neutral detergent fiber (NDF), digestibility of DM, OM, NDF, ADF and CP, and digestibility of OM in DM (Dvalue) ($P_L<0.01$) as harvesting of grass was delayed. Nitrogen intake, N output in urine, N output in faeces and N balance also linearly decreased ($P_L<0.01$) with postponed harvesting of grass for silage. DM degradability and effective degradability (ED) significantly decreased with increasing maturity of grass at harvest. The results suggest that harvesting date has a significant influence on the nutritive value of GS in terms of intake, digestibility, N balance and in sacco degradability in the rumen. It was concluded that early harvest GS ensured higher intake, digestibility, N intake and DM degradability in comparison with the medium and the late cut GS as a result of improved rumen N efficiency and utilization probably due to a better balance of available energy and protein.

• 한국치위생학회지
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• 제8권4호
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• pp.141-151
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• 2008

The purpose of this study was to examine the oral health awareness and oral health care of health-related and health-unrelated majors in an attempt to stress the importance of oral health education and boost the efficiency of oral health care. The subjects in this study were 363 college students. Out of the selected students, 174 were health-related majors, and 189 weren't. After a survey was conducted, the collected data were analyzed for the purpose of comparison, and the following findings were given: 1. Concerning daily mean toothbrushing frequency, the largest number of the male students who accounted for 55.2 percent brushed their teeth once a day on average, and the greatest number of the female students who represented 52.9 percent did that twice a day. As for the influence of their major, the largest group of the health-related majors who numbered 89(51.1%) brushed their teeth twice a day, and the greatest group of the health-unrelated majors who numbered 93(49.2%) did that once a day. The gaps between them were statistically significant(p<0.05). 2. As to the length of toothbrushing time by gender, it took more than two or three minutes for the largest groups of the male and female students that respectively numbered 96(76.8%) and 184(77.3%) to do toothbrushing(p<0.01). The greatest groups of the male and female students that respectively numbered 72(57.6%) and 183(76.9%) brushed their teeth after meals. 3. In regard to oral hygiene supplies, the largest groups of the health-related and health-unrelated majors that respectively numbered 78(44.8%) and 115(60.8%) had chewing gum and candy with them. As to the use of oral hygiene supplies, 99 health-related majors(56.9%) and 133 health-unrelated majors(70.4%) didn't put oral hygiene supplies to use. Thus, the use of oral hygiene supplies was statistically less common among the health-unrelated majors, and the gap between the two was significant(p<0.01). 4. As for health-related concern by gender, the largest group of the male students that numbered 56(44.8%) showed the most interest in preventing dental caries, and the greatest group of the female students that numbered 103(43.3%) were most concerned about tooth whitening. The gap between the male and female students was statistically significant(p<0.05), but the track of their major made no statistically significant difference to that. 5. Regarding the experience and awareness of scaling, the largest number of the students never got their teeth scaled regardless of gender and major, and the greatest group didn't care about scaling irrespective of gender and major, either, though they considered it advisable to do.

• 기본간호학회지
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• 제3권1호
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• pp.37-49
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• 1996

The Purposes of this study were to understand the types of appellations used by nurses and doctors for patients in a hospital and to analyze satisfaction and reason about appellation for patient. This would enable us to provide basic data on culturally suitable appellations for admitted patients. 454 patients at K University hospital in Seoul were subjects for this study. Subjects were interviewed individually using a questionnair and frequency $X^2-test$. Results are as follows. 1. The most frequently used type of appellations in hospitals was '-ssi ; -sir' used by 88.1% of the nurses and 83.9% of the doctors. About 3 quaters of the medical staff used '-ssi' while none used job position. 2. 93.2% of the patients were satisfied with the appellations used by nurses and 93.0% of the patients were satisfied with the appellations used by the doctors 43.7% didn't think appellations were important and 44.3% thought it natural to use the appellation. The most satisfactory form of appellation used by nurses was '-ssi' to 93.3% of patients. All were satisfied with '-nim ; -sir', '-teacher' and there was no statistically significance. On the other hand, the level of satisfaction and the appellation used by doctors showed a relationship($X^2=19.72$, p=.000). Every patient was satisfied with '-nim' and '-teacher' but 19.9% were dissatisfied with the others of appellations. 3. Most patients preferred to be called '-ssi' by nurses(77.3%) and doctors(78.7%) respectively. The dominant reason being accuracy(45.8%), naturalness(33.9%) for nurses and 43.8% and 45.4% respectively for doctors. 4. The relationship between the type of appellations requested of nurses and general characteristics showed that age($X^2=83.91%$ p=.000), level of education($X^2=33.35$ p=.000), and occupation($X^2=38.22$ p=.033) were related to the type of appellation. The type of appellation requested of doctors was related to the age($X^2=72.56$ p=.000), level of education($X^2=30.01$ p=.000), and occupation($X^2$=42.90 p=.010). Generally, '-ssi' was requested of doctors and nurses, but lower age group or higher age group(over 61), those in elementary schools or elementary school graduates snd students preferred being called by their first names or grandfather, grandmother. From the results above, we can see that the most general type of appellation used for patients by the medical staff is '-ssi' and most patients were satisfied with the appellation but, the reason being that such appellations were accepted without concern. This shows that most are not adequately satisfied with the appellation. Only a small number of people use '-nim' and '-teacher' but is the preferred and frequently used types of appellation. Therfore, a continuous research of appellations used for patients with patients using '-nim' and an investigation with nurses' opinions of appellations for patients as the subject are required.

• 대한치과보철학회지
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• 제20권1호
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• pp.51-66
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• 1982

The purpose of this study was primarily to determine the relationship between temporomandibular joint mobility and generalized benign joint hypermobility. The subjects were 85 men and 76 women, who were students of dental and dental hygiene schools, aged 18 to 30 years old. They had no disturbances or complaints of movement of temporomandibular joints and other joints in the body. The joint mobility was measured by a test which is a modification of a method developed originally by Carter and Wilkinson (1964). The mandibular mobility was measured during active and passive maximal opening, laterotrusion, protrusion, and retrusion by Ingervall's method (1970). The obtained results were as follows: 1. The distribution of joint hypermobility disclosed was 4.8% in men and 19.7% in women, and 11.8% of total subjects. 2. The joint mobility index was a mean of 0.37 for men and 0.51 for women in total subjects, and 0.80 for men and 0.73 for women in hypermobile subjects. 3. The angle of passive dorsiflexion of the little finger was greater in the left than in the right hand for both sexes and in hypermobile subjects than in total subjects. 4. There was a positive correlation between the joint mobility index and the angle of passive dorsiflexion of the little finger in total subjects. 5. The joint mobility was greater in women than in men, and in the left than in the right hand. 6. In the active maximal mandibular movements of total subjects, the mean values for the opening capacity was 56.01 mm and 52.04mm, the laterotrusion mean 8.07 and 8.08, the protrusion mean 8.72 and 8.24, and the retrusion mean 0.48 and 0.49 for men and women respectively. 7. In the passive maximal mandibular movements of total subjects, the mean values for the opening capacity was 59.07mm and 54.85mm, the laterotrusion mean 8.90 and 9.12, the protrusion mean 10.03 and 10.00, and the retrusion mean 0.69 and 0.72 in men and women respectively. The active and passive maximal opening capacity was larger in men than in women but in the other movements there were no significant differences between men and women. 8. The range of active and passive maximal mandibular movements of hypermobile subjects tended to be larger in men but no significant difference in women compared with that of total subjects. 9. The range of maximal mandibular movements was increased more in passive than in active.

• 한국지역사회생활과학회지
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• 제25권1호
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• pp.99-111
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• 2014

To verify welfare needs, rural health and environmental factors were compared between agricultural and nonagricultural groups over the past 10 years. Based on a survey of rural life by the Rural Development Administration, whose sample included agricultural (72.8%) and nonagricultural (27.2%) groups, all factors were analyzed using SAS ( 9.3). For rural home heating, the use of oil boilers (77.2%-78.0%) decreased (53.0%-53.7%) over the same period, whereas that of electric boilers increased (21.9% and 13.5% for agricultural and nonagricultural groups, respectively). The joint water- supply increased, and the use of flush toilets (52.4% to 84.5% in the agricultural group and 64.6% to 81.4% in the nonagricultural group) and hot-water bathing was higher in the agricultural group (79% to 92.6%) than in the nonagricultural group (72.2% to 87.6%) at the p<0.001 level. Incineration accounted for the largest portion of household waste until 2006, when it was replaced by other treatment methods such as the pay-per-treatment option (44.4% and 68.3% in the agricultural and nonagricultural groups, respectively) (p<0.001). Garbage disposal in 2001 was mainly burial or animal feed, but separate collection increased in 2010 (42.2% and 64.3% in the agricultural and nonagricultural groups, respectively) (p<0.001). The self-perception of health was lower in the agricultural group than in the nonagricultural group (2.96 to 2.74 on a five-point scale in the agricultural group and 3.07 to 2.98 in the nonagricultural group). Drinking decreased less in the agricultural group (criteria: one point once a week,; 1.48 to 1.20) than in the nonagricultural group (1.13 to 0.80) at p<0.001, and a similar pattern was found for smoking (p<0.001). Health screening decreased in the last 10 years (scoring based one point/1-2 times per year,: 0.94 to 0.64 in the agricultural group and 1.08 to 0.69 in the nonagricultural group;p<0.01). These results indicate that various health and environmental factors were less favorable to farmers except for bathing in comparison to nonagricultural living in the same area. This suggests that people in agriculture are less likely to live and work in favorable environments than those outside the sector and thus indicates a need for more attention to the national health welfare system for farmers for systematic realization.