• 제목/요약/키워드: -irradiation

검색결과 7,745건 처리시간 0.035초

UVB 1회 조사 후 시간에 따른 BALB/c마우스의 피부 항산화효소 활성도 변화 (Temporal changes of the activity of catalase, superoxide dismutase, and glutathione peroxidase in BALB/c mice skin after a single dose UVB irradiation)

  • 이정희;박경애;이희주;박명숙;전상은;박경찬;최스미
    • Journal of Korean Biological Nursing Science
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    • 제3권1호
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    • pp.53-61
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    • 2001
  • Skin is constantly exposed to air, solar radiation, ozone and other air pollutants formulating free radicals. The reactive oxygen species(ROS), formed under these conditions, are associated with skin cancers, cutaneous photoaging, and cutaneous inflammatory disorders. In this study, we sought to establish an animal model for UVB-induced skin alteration using BALB/c mice. The level of UVB irradiation used in this model was within physiological dose. BALB/c mice were exposed to a single dose of UVB ($200mJ/cm^2$ and were sacrificed at 3, 6, 24, and 48 hours following the irradiation. The effect of a single exposure to UVB irradiation on skin catalase(CAT), superoxide dismutase(SOD), and glutathione peroxidase(GPx) activities were examined. Significant decrease in the activity of all enzymes were observed at 6 hours after irradiation(p<.05). The activity of CAT decreased more sharply than those of SOD and GPx, and then remained depressed until 48 hours after UVB irradiation, whereas the activity of GPx recovered to basal level at 48 h after UVB irradiation. Our results indicate that BALB/c mouse could be an adequate animal model of UVB irradiation experiment. These results will also provide fundamental knowledge for the effective nursing strategies in reducing UV-induced skin disorders.

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In Vitro X선조사(線照射)가 가토폐포표면(家兎肺胞表面) 활성물질(活性物質)에 미치는 영향(影響) (Effect of X-Irradiation in Vitro on the Pulmonary Surfactant in Rabbits)

  • 조중환;주영은
    • The Korean Journal of Physiology
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    • 제5권1호
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    • pp.51-58
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    • 1971
  • In an attempt to further clarify the effect of X·irradiation on the activity of surfactant in rabbits, X-ray in dose of 900r was irradiated to the lung tissues of rabbits in vitro. Tension-area diagram of the lung extract was recorded automatically by a modified Langmuir-Wilhelmy balance with a synchronized recording system designed in this department. The surface tension of the lung extract was measured at 1,3,5,24 and 48 hours post-irradiation, and the results were compared with the non·irradiated normal group. The result$ thus obtained are summarized as follows: I The maximal surface tension, minimal surface tension, width of the tension·area diagram at the surface area of 40% in the lung extract and stability index of the normal rabbit long extract were 40.73 dynes/cm, 8.96 dynes/cm, 20.71 dynes/cm and 1.28, respectively. II. When 900r of X-ray was irradiated to the lung in vitro, 1) The maximal and minimal surface tensions did not differ noticeably from the normal at 1,3, and 5 post-irradiation hours, but the minimal surface tension increased significantly at 24 and 48 hours Post-irradiation. 2) The width of the tension area at the surface area of 40% showed a tendency of decrease throughout the experiment. 3) The stability index showed no significant change at 1,3 and 5 post-irradiation hours,but at 24 and 48 hours post-irradiation a significant decrease was observed comparing with the control. III. Activity of surfactant was significantly depressed by X·irradiation in vitro especially at 24 and 48 hours post-irradiation.

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연골세포 분화에 미치는 X-선의 영향 (The Effects of X-Irradiation on the chondrogensis of mesenchymal cells)

  • 하종렬
    • 대한방사선기술학회지:방사선기술과학
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    • 제25권2호
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    • pp.77-82
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    • 2002
  • 이미 분화된 연골세포의 성숙과정에 미치는 X-선의 작용에 대해서는 잘 알려져 있다. 그러나 연골세포나 섬유아세포, 근육세포로 분화될 수 있는 미분화 간충직 세포의 분화과정에 미치는 X-선의 영향에 대해서는 잘 알려져 있지 않아, 본 연구에서는 초기 분화연구에 좋은 대상이 되는 계배 미분화 간충직세포를 이용하여 선량(1-10Gy)에 따라 연골세포 분화 과정에 X-선이 어떤 영향을 미치는가를 조사하였다. 연구결과 선량 의존적으로 연골세포분화가 억제됨을 alcian blue로 sulfated proteoglycan을 염색한 결과를 통해 알 수 있었다. 이는 X-선이 간충직세포와 같은 성숙 이전의 연골성 세포들에게는 모두 영향을 미침을 보여주는 것이다. 또한 이미 알려진 바와 같이 X-선은 분화된 연골세포의 성숙과정에 영향을 주기도 하지만 상기 연구를 통해서 간충직세포로부터 연골세포로 분화하는 과정을 억제시키기도 함을 보여줌으로써 간충직세포로부터 성숙된 연골세포로 되는 전과정에 X-선이 영향을 미친다는 사실과, 분화가 이루어지지 않은 세포일수록 X-선 조사의 영향을 크게 받음을 알 수 있다.

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Thermal-fluid-structure coupling analysis for plate-type fuel assembly under irradiation. Part-I numerical methodology

  • Li, Yuanming;Yuan, Pan;Ren, Quan-yao;Su, Guanghui;Yu, Hongxing;Wang, Haoyu;Zheng, Meiyin;Wu, Yingwei;Ding, Shurong
    • Nuclear Engineering and Technology
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    • 제53권5호
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    • pp.1540-1555
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    • 2021
  • The plate-type fuel assembly adopted in nuclear research reactor suffers from complicated effect induced by non-uniform irradiation, which might affect its stress conditions, mechanical behavior and thermal-hydraulic performance. A reliable numerical method is of great importance to reveal the complex evolution of mechanical deformation, flow redistribution and temperature field for the plate-type fuel assembly under non-uniform irradiation. This paper is the first part of a two-part study developing the numerical methodology for the thermal-fluid-structure coupling behaviors of plate-type fuel assembly under irradiation. In this paper, the thermal-fluid-structure coupling methodology has been developed for plate-type fuel assembly under non-uniform irradiation condition by exchanging thermal-hydraulic and mechanical deformation parameters between Finite Element Model (FEM) software and Computational Fluid Dynamic (CFD) software with Mesh-based parallel Code Coupling Interface (MpCCI), which has been validated with experimental results. Based on the established methodology, the effects of non-uniform irradiation and fluid were discussed, which demonstrated that the maximum mechanical deformation with irradiation was dozens of times larger than that without irradiation and the hydraulic load on fuel plates due to differential pressure played a dominant role in the mechanical deformation.

An Experimental Study on the Relationship Between Temperature and Pressure Inside the Cup During Cupping Procedures

  • Lee, Ha Lim;An, Soo Kwang;Lee, Jae Yong;Shim, Dong Wook;Lee, Byung Ryul;Yang, Gi Young
    • Journal of Acupuncture Research
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    • 제38권1호
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    • pp.41-46
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    • 2021
  • Background: Pressure changes related to temperature variation during cupping may lead to dropout. This study aimed to investigate pressure changes related to temperature variations in the cup during the cupping procedure. Methods: Changes in temperature and pressure were measured for 15 minutes after the procedure was performed using the alcohol rub method with glass cups and with the addition of infrared irradiation. Changes in temperature and pressure were also measured for 15 minutes after pumping 3 times using the valve suction method, and with the addition of infrared irradiation. Results: In a comparison between the alcohol rub method with glass cups and with the addition of infrared irradiation, the negative pressure increased over time in the absence of infrared irradiation, whereas it decreased when performed with infrared irradiation p = 0.094. However, in a comparison between pumping 3 times using the valve suction method, and with the addition of infrared irradiation, the negative pressure decreased in both cases, but this was more significant with infrared irradiation p = 0.172. There was a significantly higher temperature in the glass cups (p = 0.004) and the valve cups (p = 0.001) exposed to infrared radiation, compared with no infrared irradiation. Conclusion: The reduction in negative pressure inside the cups exposed to infrared radiation was greater than without infrared irradiation. Temperature increases inside the cup can lead to the risk of dropout.

Effect of surface quality on hydrogen/helium irradiation behavior in tungsten

  • Chen, Hongyu;Xu, Qiu;Wang, Jiahuan;Li, Peng;Yuan, Julong;Lyu, Binghai;Wang, Jinhu;Tokunaga, Kazutoshi;Yao, Gang;Luo, Laima;Wu, Yucheng
    • Nuclear Engineering and Technology
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    • 제54권6호
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    • pp.1947-1953
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    • 2022
  • As the plasma facing material in the nuclear fusion reactor, tungsten has to bear the irradiation impact of high energy particles. The surface quality of tungsten may affect its irradiation resistance, and even affect the service life of fusion reactor. In this paper, tungsten samples with different surface quality were polished by mechanical processing, subsequently conducted by D2+ implantation and thermal desorption. D2+ implantation was performed at room temperature (RT) with the irradiation dose of 1 × 1021 D2+/m2 by 5 keV D2+ ions, and thermal desorption spectroscopy measurements were done from RT to 900 K. In addition, He irradiation was also performed by 50 eV He+ ions energy with the fluxes of 5.5 × 1021 m-2s-1 and 1.5 × 1022 m-2s-1, respectively. Results reveal that the hydrogen/helium irradiation behavior are both related to surface quality. Samples with high surface quality has superior D2+ retention behavior with less D2 retained after implantation. However, such samples are more likely to generate fuzzes on the surface after helium irradiation. Different morphologies (smooth, wavy, pyramids) after helium irradiation also demonstrates that the surface morphology is related to tungsten crystallographic orientation.

Selective Laser Melting 방식으로 적층제조된 Inconel 718 합금의 조사 경화 특성 (Irradiation Hardening Property of Inconel 718 Alloy produced by Selective Laser Melting)

  • 서주원;임상엽;진형하;천영범;강석훈;한흥남
    • 한국분말재료학회지
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    • 제30권5호
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    • pp.431-435
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    • 2023
  • An irradiation hardening of Inconel 718 produced by selective laser melting (SLM) was studied based on the microstructural observation and mechanical behavior. Ion irradiation for emulating neutron irradiation has been proposed owing to advantages such as low radiation emission and short experimental periods. To prevent softening caused by the dissolution of γ' and γ" precipitates due to irradiation, only solution annealing (SA) was performed. SLM SA Inconel 718 specimen was ion irradiated to demonstrate the difference in microstructure and mechanical properties between the irradiated and non-irradiated specimens. After exposing specimens to Fe3+ ions irradiation up to 100 dpa (displacement per atom) at an ambient temperature, the hardness of irradiated specimens was measured by nano-indentation as a function of depth. The depth distribution profile of Fe3+ and dpa were calculated by the Monte Carlo SRIM (Stopping and Range of Ions in Matter)-2013 code under the assumption of the displacement threshold energy of 40 eV. A transmission electron microscope was utilized to observe the formation of irradiation defects such as dislocation loops. This study reveals that the Frank partial dislocation loops induce irradiation hardening of SLM SA Inconel 718 specimens.

UV/Ozone 조사에 의한 PTT 필름의 연속식 표면처리와 염색성 (Continuous Surface Treatment and Dyeability of PTT Film via $UV/O_3$ Irradiation)

  • 장진호;박대선
    • 한국염색가공학회지
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    • 제17권1호
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    • pp.7-13
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    • 2005
  • Continuous and intense UV irradiation on PTT film using two types of UV bulbs at different irradiation power level was carried out to modify surface characteristics of the film including zeta potential, wettability, surface energy, and dyeability. ESCA analysis of the irradiated film showed higher O/C ratio than the untreated film indicating photooxidation of outer surface layer. ATR analysis showed that the ester bonds were broken and some new groups were produced such as carboxylic acid, phenolic hydroxy, and other esters, implying that ester bonds of PTT was responsible for the observed photooxidation effect. The surface of the treated PTT film became more hydrophilic and wettable to water, coupled with increased surface energy. Polar component of the surface energy increased and nonpolar component decreased with increasing irradiation energy. The treatment also decreased zeta potential of the modified surface and nanoscale roughness increased with increasing irradiation. The dyeability of the treated films to catonic dyes was significantly improved by electrostatic and polar interaction between dye molecules and the anionic film surface. The UV irradiation seems to be a viable polymer surface modification technology, which has advantages such as no vacuum requirement and continuous process unlike plasma treatment.

방사선 조사 돼지고기에서 휘발성 조사물질의 구명 (Identification of Irradiation-induced Volatile Flavor Compounds in Irradiated Pork Meats)

  • 차용준;김훈;조우진;정연정;변명우;유영재
    • 생명과학회지
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    • 제11권1호
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    • pp.35-42
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    • 2001
  • Irradiation-induced volatile flavor compounds in irradiated (0, 1, 3, 5, 10 kGy) pork meats were analyzed by liquid liquid continuous extraction (LLCE) and gas chromatography/mass spectrometry (GC/MS) methods. One hundred nine volatile compounds were detected in irradiated pork meats. These compounds were mainly composed of hydrocarbons (42 compounds), aromatic compounds (39), aldehydes(9), ketones(5) and miscellaneous compounds (14). Among these, three volatile compounds, such as decene, 1,2,3,4,-tetrahydro-6-methylnaphthalene and 1,2,3,4-tetrahydro-dimethylnaphthalene were selected as irradiation-induced compounds comparing with irradiation dosages in irradiated pork meats. By the high correlation coefficient with the increment of irradiation dose, however, decene (r=0.93) was considered as marker compound for detecting irradiation dosage in fresh pork meats.

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Effect of Microwave Irradiation on Crystallinity and Pasting Viscosity of Corn Starches Different in Amylose Content

  • Lee, Su-Jin;Sandhu, Kawaljit Singh;Lim, Seung-Taik
    • Food Science and Biotechnology
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    • 제16권5호
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    • pp.832-835
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    • 2007
  • Moisture content of normal, waxy, and high amylose com starches was adjusted to 10-35%, and irradiated in a microwave oven. The effect of microwave irradiation on the crystalline structure of starch was measured by using a differential scanning calorimetry (DSC), and X-ray diffractometry. Pasting viscosity profile was also determined by using a rapid viscoanalyzer (RVA). For all the 3 types of starches tested, the rate of temperature increase by the microwave irradiation was faster and more rapidly reached the maximum temperature of the pressure bomb ($120^{\circ}C$) when the moisture content was higher. X-ray diffraction and DSC data revealed that the microwave irradiated starch underwent partial disruption of crystalline structure. RVA studies showed that the irradiation caused significant reductions in maximal viscosity and breakdown, whereas pasting temperature was increased. Overall trends revealed that the microwave irradiation on the starch containing limited moisture content (less than 35%) provided the effects similar to the heat moisture treatment. These effects became more significant when the moisture content was higher. Compared to waxy com starch, normal, and high amylose com starches appeared to be more susceptible to the microwave irradiation.