• Bioinformatics and Biosystems
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• v.1 no.2
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• pp.103-108
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• 2006

Computational prediction of protein-ligand binding has been widely used as a tool to discover lead compounds fur new drugs. Prediction accuracy is determined in part by the scoring function used in docking calculations. Diverse scoring functions are available, and these can be classified into force-field based, empirical, and knowledge-based functions depending upon the basic assumptions made in development. Among these, force-field based functions consider physical interactions the most in detail. However, the force-field based functions have the drawback of not including the entropic effect while considering only the energy contribution such as dispersion or electrostatic forces. In this article, a method to take into account of the entropic effect using the colony energy is suggested when force-field based scoring functions is used by extracting conformational information obtained from the pre-existing docking program. An improved result for decoy discrimination is illustrated when the method is applied to the DOCK scoring function, and this implies that more accurate docking calculation is possible.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.28 no.3
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• pp.325-333
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• 2015

Recently, thermal bridge breaker systems(TBBSs) applicable to RC slab-wall connections have been increasingly studied and proposed. This study also aims at proposing an analytic model which is applicable to predicting the flexural behavior of TBBS embedded in slabs from the initial elastic stages, yield states to ultimate conditions. The analytic models are developed by considering strain compatibility, force equilibrium and the constitutive law obtained from material test results. To verify the accuracy of the proposed analytic model, the moment-curvature relationship and change of neutral axis according to the loading states are compared with those of experimental results. Based on the comparison, it is verified that the proposed analytic model provides well predict the flexural behavior of TBBS embedded in slabs.

• Korean Journal of Agricultural Science
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• v.30 no.2
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• pp.164-174
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• 2003

This study was performed to suggest a rational method for the stability evaluation of agricultural reservoir in the very soft ground. The stability methods for agricultural reservoir was used to compare and analyze with various condition by limit equilibrium method. The behavior of settlement-displacement obtained by field monitoring system was used to compare and analyze with various stability methods, and to investigate the applicability of the methods for stability evaluation of agricultural reservoir. The horizontal displacement was abruptly increased when physical properties of soft clay reached its maximum values and therefore, the values of these properties could be used to the fundamental data for stability evaluation. The evaluation of the stability of agricultural reservoir was suggested to use the inclination of curve rather than critical line.

• Journal of the Korean Geotechnical Society
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• v.30 no.10
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• pp.55-65
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• 2014

Recent researches on debris flow is focused on understanding its movement mechanism and building a numerical simulator to predict its behavior. However, previous simulators emulating fluid-like debris flow have limitations in numerical stability, geometric modeling and application of various boundary conditions. In this study, depth integration is applied to continuity equation and force equilibrium for debris flow. Thickness of sediment, and average velocities in x and y flow direction are chosen for main variables in the analysis, which improve numerical stability in the area with zero thickness. Petrov-Galerkin formulation uses a discontinuous test function of the weighted matrix from DG scheme. Presented mechanical constitutive model combines fluid and granular behaviors for debris flow. Effects on slope angle, inducing debris height, and bottom friction resistance are investigated for a simple slope. Numerical results also show the effect of embankment at the bottom of the slope. Developed numerical simulator can assess various risk factors for the expected area of debris flow, and facilitate embankment design in order to minimize damage.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.41 no.6
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• pp.429-434
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• 2017

A molecular-continuum hybrid method was developed to simulate microscale and nanoscale fluids where continuum fluidics cannot be used to predict Couette flow. Molecular dynamics simulation is used near the solid surface where the flow cannot be predicted by continuum fluidics, and Navier-Stokes equations are used in the other regions. Numerical simulation of Couette flow was performed using the hybrid method to investigate the effect of solid-liquid interaction and surface roughness in a nanochannel. It was found that the solid-liquid interaction and surface roughness influence the boundary condition. When the surface energy is low, slippage occurs near the solid surface, and the magnitude of slippage decreases with increase in surface energy. When the surface energy is high, a locking boundary condition is formed. The roughness disturbs slippage near the solid surface and promotes the locking boundary condition.

• Journal of the Korean association of regional geographers
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• v.18 no.4
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• pp.374-387
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• 2012

EU's future frontier remains indefinite but it is directly linked to the principle of entry into the EU. EU has been defining that the 'european nation' sharing with a EU's value and norms can enter into the EU. If so, what is the criteria of EU? The criterion of 'european nation' will be a theoretical basis of an estimation of the EU's future frontier. However, the future frontier based on the geography, the culture and the intension of nation is only the potential frontier. It will be changed by the political decision makers' negotiation and power. EU's enlargement policy is one of means to retention of the international power in the situation that a few nations gradually dominate the world. Therefore the EU's frontier will be continually changed and created by the EU's political adventure.

• Journal of the Korean Society for Railway
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• v.10 no.6
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• pp.806-811
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• 2007

The derailment is defined as phenomena in which the wheels run off the rail due to inordinate lateral force generated when wheel flange contacts with the rail. Derailment coefficient is typical standard assessing running safety and derailment. The traditional method measuring by strain gage adhered to wheels is very complicated and easy to fail. It also requires too much cost and higher measurement technique. Therefore it can hardly ensure safety because we can't confirm at which time we need to identify safety. In this paper, we principally researched the method measuring easily wheel load generated by contacts between wheel flange and the rail, and lateral force. Correlation of vibration and displacement which was related physical amounts of wheel load and lateral force, was investigated and analyzed through analysis, experiment and measurement. And it is presents new measurement method of derailment coefficient which can estimate derailment possibility only by movement of vibration and displacement, by which we understand the rate for acceleration and displacement to contribute wheel load and lateral force and compare actual data of wheel load and lateral force measured from wheel.

• Korean journal of communication and information
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• v.20
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• pp.7-32
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• 2003

This essay provides a critical introduction to some of the major issues relating to ITV Digital. The demise of ITV Digital has hit the economics of broadcasting industry in UK. ITV Digital's failure is seen as digital nightmare. This study approaches to three dimensions of the failed ITV Digital. There are the failure of policy, business strategy, technological debacle. As I have discussed, competitive environment of digital broadcasting squeezed ITV Digital into financial trouble. In order to examine current development of digital terrestrial television, three questions have been raised. First, What is the government of digital broadcasting? Second, What is the business strategy of ITV Digital? In particular, the failure of business model deserved careful watching. Third, What is the failure of digital technology?

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.20 no.2
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• pp.96-104
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• 1984

This paper is on the prediction and response of the ship hull girder due to slamming of foreward flat bottom plate. The response with respect to foreward flat bottom is divided two kinds by estimating method. One is the estimation of impact forces by slamming, Another is the response of hull girder due to impact forces, that is, displacement, velocity, acceleration, etc. must calculate the values for considered ship hull girder. In this paper, therefore, was estimated only impact forces along ship ordinate of foreward. The analysis of data for estimation followed mainly papers of Ochi. These estimated data shall contribute for ship gull construction for basic optimum design. In particular, the estimated impact forces shall be given for the response of ship gull girder on the foreward flat bottom plate with characteristics of external forces.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.4B
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• pp.647-658
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• 2010

Many localization schemes estimate the locations of radio nodes based on the physical locations of anchors and the connectivity from the anchors. Since they only consider the knowledge of the anchors without else other nodes, they are likely to have enormous error in location estimate unless the range information from the anchors is accurate or there are sufficiently many anchors. In this paper, we propose a novel localization algorithm with the location knowledge of anchors and even one-hop neighbors to localize unknown nodes in the uniform distance from all the one-hop neighbors without the range information. The node in the uniform distance to its all neighbors reduces the location error relative to the neighbors. It further alleviates the location error between its actual and estimated locations. We evaluate our algorithm through extensive simulations under a variety of node densities and anchor placement methods.