• Journal of Nutrition and Health
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• v.15 no.1
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• pp.1-8
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• 1982

The effects of lactose on the formation of casein phosphopeptide (CPP), the increment of soluble calcium and the enhancement of calcium absorption by dietary casein in the intestinal tract were investigated. Rats were fed a lactose-free diet, 10% lactose diet and 30% lactose diet containing powdered milk. In rats receiving a lactose-free powdered milk diet, CPP formation was confirmed by gel filtration of the intestinal content on Sephadex G -25 and the amount of soluble calcium was increased in the small intestine and calcium absorption, measured by the ligated ideal loops in situ was enhanced. However, In rats receiving a powdered milk diet containing 10% lactose or 30% lactose, the similar effects were not seen. These observations indicate that CPP-stimulated effects on soluble calcium and calcium absorption in the small intestine are not dependent upon lactose.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6439-6444
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• 2015

With increasing concern about global warming, CCS (Carbon dioxide capture and storage) has attracted much attention as a promising technology for reducing $CO_2$ emission. It is necessary to develop the cost-effective absorbents materials in order to rapid commercialize CCS technologies. In this work, he study for the promotion of absorption rate in $CO_2$ capture system using metal nanoparticle were investigated. Three kinds of metal nanoparticle, cobalt, zinc, and nickel, were prepared by wet and dry method and effect of preparation method on the absorption rate of $CO_2$ were compared. Among the tested using pH method, nickel nanoparticle prepared by wet method showed the most significant improvement of $CO_2$ absorption rate. In case that metal nanoparticle is applied to CCS process, it is expected to be more efficient in $CO_2$ capture process due to reduce the size of absorption tower.

• Journal of Ginseng Research
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• v.31 no.3
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• pp.154-158
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• 2007

In order to increase the content of germanium in ginseng adventitious roots, the effects of chelating agents on germanium content and root growth were investigated in the submerged cultures of ginseng adventitious roots. Chelating agents such as citric acid, oxalic acid, phosphoric acid, EDTA (Ethylenediamine tetraacetic acid) or EGTA (Ethylene glycol-bis $({\beta}-aminoethylether)-tetraacetic$ acid) were administrated in the submerged culture of ginseng root containing 50 ppm $GeO_2$. After 6 weeks of cultivation, fresh weight, germanium and saponin contents in the roots were analyzed. Among chelating agents, addition of 1.0mM phosphoric acid was found to be best for germanium accumulation. Under this condition, germanium content increased 1.4 times as compared to that of the control. The germanium content in the adventitious roots also increased with addition of EDTA or EGTA, while they inhibited the growth of ginseng adventitious root. Citric and oxalic acids were not effective for increasing germanium content in adventitious roots. As the results, it suggests that the phosphoric acid can be proved as the optimal agent for the enhancement of germanium accumulation in ginseng adventitious roots. These results can be served as a guideline for the mass production of ginseng adventitious roots containing germanium by large-scale production.

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.328-334
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• 2000

This research was concerned with the enhancement of heat transfer by surfactant added to the aqueous solution of LiBr. Different horizontal tubes were tested with and without an additive of normal octyl alcohol. The test tubes were a bare tube, floral tube, hydrophilic tube. The additive concentration was about $0.05{\sim}5.5mass%$. The heat transfer coefficient was measured as a function of solution flow rate in the range of $0.01{\sim}0.034 kg/ms$. The experimental result were compared with cases without surfactant. The enhancement of heat transfer by Marangoni convection effect which was generated by addition of the surfactant is observed in each test tube.

• 전기의세계
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• v.20 no.5
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• pp.23-26
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• 1971

본고에서는 Hippel교수가 제창하고 있는 분자공학론적인 사고방식을 대학인이 빨리 흡수 소화하여 보급하므로서 급진해 가는 산업의 추세에 발맞추어 종래의 현상론적인 Ready made식 방법의 보수성에서 탈피하여 혁신적인 Order made식 방법으로 전환시키게 노력하여야 한다고 생각한다. 그러므로 우리나라 산업의 발전 촉진제로서의 조력이 되며 대학인으로서의 직무를 완수하는 것이 될 것이다. 그럼 분자공학론적방법이란 무엇인가 설명해 보기로 한다.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.8
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• pp.1097-1103
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• 2000

This research was concerned with the enhancement of heat transfer by surfactant added to the aqueous solution of LiBr. Different horizontal tubes were tested with and without an additive of normal octyl alcohol. The test tubes were a bare tube, floral tube and hydrophilic tube. The additive mass concentration was about 0.05${\sim}$5.5%. The heat transfer coefficient was measured as a function of solution flow rate for the range of 0.01${\sim}$0.034 kg/ms. The experimental results were compared with cases without surfactant. The enhancement of heat transfer by Marangoni convection effect generated by the addition of the surfactant is observed in each test tube. The increase of heat transfer coefficient by surfactant addition is about 35${\sim}$90% for bare tube, 40${\sim}$70% for the floral tube, 30${\sim}$50% for the hydrophilic tube and was higher for the cases with smaller a little solution flow rates.

• Journal of Life Science
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• v.31 no.1
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• pp.1-9
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• 2021

Brown seaweeds have been shown to decrease blood glucose levels and improve insulin sensitivity previously. In this study, we investigated the effect of fucoidan, a complex polysaccharide derived from brown seaweeds, on glucose uptake to improve insulin resistance, and examined its mechanism of action in 3T3-L1 adipocytes. We observed that fucoidan significantly increased glucose uptake and it was related to an increased expression of plasma membrane-glucose transporter 4 (PM-GLUT4) in 3T3-L1 adipocytes. Fucoidan treatment increased the activation of phosphatidylinositol-3-kinase (PI3K) and the phosphorylation of insulin receptor substrate 1 (IRS1tyr) compared with that of the control cells. Fucoidan also promoted the phosphorylation of Akt and protein kinase C (PKC)-λ/ζ compared to that of the control cells. Moreover, fucoidan significantly upregulated acetyl-CoA-carboxylase (ACC) and adenosine monophosphate - activated protein kinase (AMPK) phosphorylation. As a result, translocation of GLUT4 was significantly enhanced in 3T3-L1 adipocytes, which significantly promoted glucose uptake via the PI3K/AMPK pathways. The elevation of glucose uptake by fucoidan was blocked by inhibitor of PI3K and inhibitor of AMPK in 3T3-L1 adipocytes. These findings indicate that fucoidan might ameliorate glucose uptake through GLUT4 translocation to the plasma membrane by activating the PI3K/Akt and AMPK pathways in 3T3-L1 adipocytes. Fucoidan is thought to be of high material value to diabetes treatments and functional foods.

• Journal of dental hygiene science
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• v.6 no.1
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• pp.1-9
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• 2006

Cathepsin K (cat K) is the major cysteine protease expressed in osteoclasts and was thought to play a key role in matrix degradation during bone resorption. It was shown that the intracellular maturation of cat K was prevented by the cAMP antagonist, Rp-cAMP, and the protein kinase A (PKA) inhibitors of KT5720 and H89. In contrast, forskolin, a adenylate cyclase agonist, rather induced Cat K processing and maturation in osteoclasts. Furthermore, to determine whether cat K processing and maturation signaling involves protein kinase C (PKC), mouse total bone cells were treated with calphostin C, a specific inhibitor of PKC, however, no effect was observed, indicating that calphostin C did not affect to osteoclast-mediated cat K processing and maturation. Thus, it is indicated that the cAMP-PKA signaling pathway regulates cat K maturation in osteoclasts. Since secreted proenzymes have the potential to reenter the cell via M6P receptor, to prevent this possibility, it was tested cAMP antagonist Rp-cAMP and the PKA inhibitors KT5720 and H89 in the absence or presence of M6P. Inhibition of cat K processing by Rp-cAMP, KT5720, or H89 was observed in a dose-dependent manner. Furthermore, the addition of M6P resulted in enhanced potency of Rp-cAMP, KT5720 and H89. These dose-dependently inhibited in vitro bone resorption with a potency similar to that observed for inhibition of cat K processing.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.9
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• pp.895-900
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• 2012

This paper aims to examine the effect of nanodroplets on pool-type absorption heat transfer enhancement and to find the relationship between the dispersion stability and the absorption performance. The concentrations of oil and surfactant are considered as the key parameters. $C_{12}E_4$ and Tween20 are used as the surfactants and N-decane oil is added to the $NH_3/H_2O$ solution to make the binary nanoemulsion fluids. Binary nanoemulsion fluids are dispersed by the ultrasonic vibrator and the stirrer under specific conditions. The dispersion stability of binary nanoemulsion fluids for each oil concentrations is evaluated from the droplet size and Tyndall effect analysis. The absorption performance of binary nanoemulsion fluids is compared with the result of dispersion stability. In addition, it is found that the binary nanoemulsion fluid is a strong candidate as a new working fluid for absorption applications.

• Monthly Korean Chicken
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• v.18 no.2
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• pp.122-127
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• 2012

계사내 공기중의 암모니아 농도 감소 목적으로 식물 기원 소화율 촉진제(phytogenic digestibility enhancer) 사용이 가능하다. 이 소화율 촉진제는 사료 설계 명세서 내 특정 성분(조단백질)을 감소시키고 영양소 이용성을 개선하여 동물생산성을 향상시키기 때문이다. 조단백질 함량이 낮은 사료 급여는 가금에게 적정 요구량 이상 흡수된 단백질(excess protein)의 뇨산(尿酸 : uric acid) 전환에 에너지를 소비하지 않아서 열역학적 이점(熱力學的 利點 : energetic advantage)이 있고, 이 에너지는 유익한 성장에 사용이 가능하도록 존재한다. 더욱이 동물 사료 중 조 단백질 1%는 약 3% 더 많은 물의 섭치가 필요하고, 그 중 80%는 다시 배설되므로 단백질 함량 적정화 사료들(protein optimized diets)은 음수 요구량을 감소시킨다. 이러한 단백질 적정화 사료는 동물 사육업자들에게 관심의 대상으로 명확한 경제적 이득이 발생한다.