• Title/Summary/Keyword: 흑색종

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Comparative Morphology of Tanakius kitaharae and Glyptocephalus stelleri (Pleuronectidae) Larvae (갈가자미, Tanakius kitaharae와 기름가자미, Glyptocephalus stelleri (가자미과) 자어의 형태 비교)

  • Jang, Seo-Ha;Jung, Kyung-mi;Park, Jeong-Ho;Kim, Jin-Koo
    • Korean Journal of Ichthyology
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    • v.28 no.3
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    • pp.164-174
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    • 2016
  • Tanakius kitaharae and Glyptocephalus stelleri, belonging to the family Pleuronectidae, were very similar in external morphology not only during adult periods, but also during larval periods. In this study, we compared larval development and growth of the two pleuronectids species in detail. Fifty-eight specimens of T. kitaharae larvae and five specimens of G. stelleri larvae were collected from the East Sea, southern Korean Strait, and the adjacent waters of Jeju Island during 2014~2016, and were identified using morphological and molecular markers. Flexion larvae of T. kitaharae (10.23~16.77 mm total length, TL) and G. stelleri (14.33 mm TL) were similar in morphometrics, but can be distinguished by the melanophores in the fin membranes (present in the former vs. absent in the latter), and the melanophores at posterior margin of shoulder girdle (absent in the former vs. present in the latter). Postflexion larvae of T. kitaharae (17.12~24.92 mm TL) and G. stelleri (27.71~32.95 mm TL) differed in the number of melanophores on the mid-lateral caudal region (two in the former vs. five in the latter), and that on the dorsal and anal fin pterygiophores (five or six in the former vs. one row in the latter). Tanakius kitaharae and G. stelleri larvae differed in size at the beginning of metamorphosis. The left eye of T. kitaharae larvae between 23.13~24.92 mm TL reached the dorsal margin of the head while that of G. stelleri larvae between 38.66~42.67 mm TL did not reached yet.

The Inhibitory Effects of Cannabinoids of Cannabis Against Human Skin Melanoma Cells (마자인의 카나비노이드가 인체피부흑색종세포에 미치는 억제효과)

  • Lee Ki-Nam;Kim Meung-Shin;Back Seung-Hwa
    • Journal of Society of Preventive Korean Medicine
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    • v.2 no.1
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    • pp.13-30
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    • 1998
  • Geraniol (1), olivetol (2), cannabinoids (3 and 4) and 5-fluorou.a.il (5). were tested for their growth inhibitory effects against SK-MEL-3 cell lines using two different 3-(4,5-dimethylthiazol- 2yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and sulforhodamine B protein (SRB) assay. These compounds showed inhibitory activity in vitro in the micromolar range against SK-MEL-3 cell lines. In general, the antitumor activity of these compounds (1, 2, 3, 4 and 5) was in a dose-dependent over the micromolar concentration range $1\;to\;100{\mu}M$. The comparison of $IC_{50}$ values of these compounds in tumor cell lines shows that their susceptibility to these compounds decrease in the following order : OLVTL > CBG > CBD > 5-FU > CRNL in MTT assay, CBG > OLVTL > CBD > GRNL > 5-FU in SRB assay. Cannabinoids (3 and 4) and 5-fluorouracil (5) were tested for their cytotoxic effects on NIH 373 fibroblasts using two different MTT assay and SRB assay. These compounds exhibited potent cytotoxic activities in vitro in the micromolar range against NIH 373 fibroblasts. In general, the cytotoxic activities of these compounds (3, 4 and 5) were in a dose-dependent over the micromolar concentration range $1\;to\;100{\mu}M$. The comparison of $CD_{50}$ values of these compounds on NIH 373 fibroblasts shows that their susceptibility to these compounds decrease on the following order ; CBD > 5-FU > CBG in MTT assay and SRB assay. Cannabigerol (3) was shown the least cytotoxic activity on NIH 373 fibroblasts. Cannabigerol (3) exhibited the most growth-inhibitory activity against SK-MEL-3 cell lines.

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The Analysis of Post Operative Treatment of Malignant Melanoma Using High Dose Interferon-${\alpha}2b$ Immunotherapy: Preliminary Report (악성흑색종 환자군에서 수술적 치료 후 시행한 고용량 인터페론-${\alpha}2b$ 면역요법에 의한 보조적 치료 결과 분석: 예비보고)

  • Chung, So Hak;Jo, Hyun Ik
    • The Journal of the Korean bone and joint tumor society
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    • v.18 no.2
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    • pp.78-82
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    • 2012
  • Purpose: Interferon-${\alpha}2b$ using immunotherapy of malignant melanoma is known to increase the microscopic enemies that remain after surgical resection of the tumor to prevent recurrence, disease-free survival and overall survival. Authors in patients with malignant melanoma after surgical resection and high-dose interferon-${\alpha}$ immunotherapy treated group of disease-free survival and overall survival compared with the results of the treatment of immune therapy to a preliminary report. Materials and Methods: From February 2010 to October 2012 at our institution between being diagnosed with malignant melanoma after surgical immunotherapy treated patients were analyzed. Patients was evaluated using the stage AJCC stage IIA 3 cases, IIB 1 cases, IV 1 were as follows. Follow-up period of at least 7 months, and a maximum of 32 months. As maintenance therapy after the first induction therapy group underwent immunotherapy interferon-${\alpha}$ of body-surface area per 200,000 IU five times in a week for 4 weeks sedentary and body surface area a total of 48 weeks per week to 100,000 IU three times subcutaneously. These patients for local recurrence and metastases, and distant metastasis were investigated disease-free survival was investigated. Results: Interferon-evaluation through follow-up chest computed tomography (CT) and positron emission computed tomography (PET CT) in patients who underwent the ${\alpha}$ immunotherapy results above both local recurrence and metastases without evidence of distant metastases. Conclusion: The high-dose ${\alpha}2b$ immunotherapy performed in patients to prevent the local recurrence of the tumor and metastasis to the current or future ultimate survival and disease-free survival improvement achieved is additional study and follow-up will be needed.

MALIGNANT MELANOMA OF THE ORAL CAVITY;REPORT OF TWO CASES (구강내 발생한 악성 흑색종)

  • Yang, Dong-Kyu;Chung, In-Kyo;Kim, Jong-Ryoul;Choi, Kab-Rim;Park, Sang-Jun;Moon, One-Ryong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.12 no.1
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    • pp.135-141
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    • 1990
  • Malignant Melanoma refers to a malignant neoplasm of melanocytes. Primary malignant melanoma of oral cavity is rare. Most frequent site of primary oral malignant melanoma are palate & gingiva. We have experienced 2 cases of malignant melanoma of the mouth. In one case, we performed wide surgical excision which was followed by chemotherapy with DTIC. In the other case, performed wide surgical excision only. There is no evidence of recurrence or of metastasis of the lesions 22 months, 12 months after operation, respectively.

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Biological Control of Garlic White Rot Accused by Sclereotium cepivorum and Sclereotium sp. Using Bacillus subtilis 122 and Trichoderma harzianum 23 (Bacillus subtilis 122와 Trichoderma harzianum 23에 의한 마늘 흑색썩음균핵병의 생물적 방제)

  • Lee Sang-Yeob;Lee Sang-Bum;Kim Yong-Ki;Hwang Soon-Jin
    • Research in Plant Disease
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    • v.12 no.2
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    • pp.81-84
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    • 2006
  • Trichoderma harzianum 23 WP and Bacillus subtilis 122 WP were formulated as antagonists of Sclerotium cepivorum and Sclerotium sp. of garlic white rot. In the field test, applications of Trichoderma harzianum WP and Bacillus subtilis WP reduced garlic white rot by Sclerotium cepivrum from 10.9% in the control to 4.1% and 6.2%, respectively at Taean. Also at Seosan, applications of Trichoderma harzianum 23 WP and Bacillus subtilis 122 WP reduced garlic white rot by Sclerotium sp. from 17.8% in the control to 1.2% and 2.6%, respectively. Treatment of Trichoderma harzianum 23 WP and Bacillus subtilis 122 WP increased garlic yield in two area. Therefore, Trichoderma harzianum 23 WP and Bacillus subtilis 122 WP have shown potential as biofungicides of garlic white rot in the two different pathogens.

Studies on a Korean Unrecorded Phamphilid -sawfly (Hymenoptera, Symphyta) Feeding on Korean Pine. taxonomical and Morphological Studies (잣나무를 식해한는 한국미기록종 넓적잎벌(막혈목, 고아요아목) 에 관한 연구 (I)-형태 및 분류학적 연구)

  • 이덕상
    • The Korean Journal of Zoology
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    • v.4 no.1
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    • pp.1-6
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    • 1961
  • 본 논문은 경기도광릉시험목에서 잣나무를 식해하는 한국미기록종 잣나무넓적잎벌(신칭)을 재료로 하여 1958-1961 년에 연구한 것을 기록한 것이다. (1) 본충은 막혈목 광요아목 편엽봉과의 Acantholyda nemoralis에 해당하는 것으로서, 이것의 학명으로는 R.B.Benson T의 설에 따라 Acantholyda posticalis posticalis MATSU.MURA를 채용하기로하였다. (2) 분포지로는 개지의 일본, 몽고, 시베리아 외에 한국을 추가한다. 구라파에서는 별개의 아종이 있다. 본종의 서식지로는 현재까지 경기도의 광fmd, 가평, 양주와 강원도의 충성군이 알려져있을 뿐이다. (3) 성충의 체색은 대체로 흑색이나, 두부와 훙부에 황색의 무늬가 많\ulcorner. 촉색은 황갈색 사상으로 유충은 웅충은 33절, 자충은 32절로 되었다. (4) 란은 QH트형으로 그 양단이 상외방으로 돌출, 산란직후의 색은 광택있는 담황갈색을 정하나 3일이 경과하면 담자황록색으로 변한다. 길이 약 3 mm , 폭 약 0.7mm이다. (5) 부화유충의 채색은 대적황색이나 , 머리와 흉곽은 흑색이다. 머리가 크고 몸통은 가늘다. 체장 약 3.5mm, 체폭 약 0.7mm. 성열유충의 체색은 담황갈색이나, 배선 및 기문상선은 선명한 적색이다. 3상의 흉곽과 한쌍의 미각이 있고, 망막은 없다. 두부는 키틴질화하였고, 갈색이며, 촉색은 7 절로되어 있고 대사가 발달하였다. 체장 약 27.4mm, 체폭 약 4.5mm , 전용은 적색의 배선 및 기문상선이 없고, 전신이 등황색이며, 촉색의 배측에 칠흑색의 커다란 복안을 가지고있는 점등이 성열유충과 다른 점이다. 암컷이 될 것은 크고 (체장 약 20-26mm), 수컷이 될 것은 작다(체장 약 3-17mm). (6) 용은 나용으로 용화직전의 것은 단지 복안과 단안만이 흑색을 정하고 , 타부분은 전부황색이지만 시간이 경과함에 따라 색이 변한다. 체장 약 17mm, 체폭 약 5mm.

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First Morphological Description of a Larval Sleek Unicornfish Naso hexacanthus(Acanthuridae, Perciformes) Identified by COI Barcoding in the East China Sea (COI 바코딩으로 동정한 남방표문쥐치(Naso hexacanthus) 치어의 첫 형태 기재)

  • Choi, Hae-young;Choi, Hee-chan;Kim, Sung;Oh, Hyun-ju;Youn, Seok-hyun
    • Korean Journal of Ichthyology
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    • v.34 no.2
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    • pp.119-126
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    • 2022
  • Here, we present the first morphological description of a larval Naso hexacanthus (5.2 mm in body length) from the East China Sea identified by cytochrome c oxidase subunit I (COI) barcoding. The larva had a kite-shaped body with long serrated first spine of dorsal and anal fins. There were four melanophores on the base of the anal fin, dense melanophores on the caudal peduncle, and scattered melanophores on the surface of the brain. There was one small spine on the snout and behind each eye, with serrations on the head, top of the eye, inner- and outer-preopercle, and on the lower part and side of the opercle. The morphological characteristics of larval N. hexacanthus identified by COI barcoding will be useful for species identification of larval fish.

A Comparative Study on Physiological Characters Between the Cultivar and Wild Plant in Amaranthus sp. (비름과(科)(Amaranthus sp.) 식물(植物)의 재배종(栽培種)과 야생종간(野生種間)의 생리학적(生理學的) 특성비교(特性比較))

  • Cheong, Jang Hee;Choi, Kwan Sam
    • Korean Journal of Agricultural Science
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    • v.14 no.1
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    • pp.38-50
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    • 1987
  • The purpose of this comparative study is to investigate the differences of growth behaviors (height, weight, yield capacities etc.) and germination characters (induced photo-dormancy) among the three different species of Arnaranthus sp. The results obtained are summarized as follows. The growth of the cultivar of A.hypochondriacus was more vigor than that of the wild plant of A.retroflexus during the whole life cycle. The fresh weight, dry weight, yield capacity of A.hypochondriacus were much more higher than those of the others two species (A.retroflexus and A.Cruenthus). There are very different germinability formation and induced dormancy patterns between the cultivar and wild plant during seed formation periods. The cultivar of A.hypochondriacus was not induced primary dormancy in the any seed formation stages but wild plant of A.retroflexus was induced deep true dormancy. We suggested that these differences occured by the sum of different absorption of solar energy spectrum by the different seed colors between the cultivar (white color seed) and wild (black seed). And we confirmed the different absorption spectrum of the three different Arnaranthus sp. seeds.

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Effects of Sowing Dates and Black P.E. Film Mulching on the Growth and Yield in Achyranthes japonica N. (파종기별(播種期別) 흑색(黑色)비닐피복(被覆)이 쇠무릎의 생육(生育) 및 수량(收量)에 미치는 영향(影響))

  • Kim, Myoung-Seok;Park, Gyu-Chul;Chung, Byoung-Jun;Park, Tae-Dong;Kim, Chang-Chul;Shim, Jae-Han
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.2
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    • pp.91-94
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    • 1997
  • This experiment was carried out to investigate the effects of black P.E. film mulching by different sowing dates on the growth and yield of Achyranthes japonia NAKAI. Emergence rate and the growth increment were increased in black polyethylene (P.E.) film mulching of sowing date at April 1. Dried root yield was highest by 3,190kg/ha in black P.E. film mulching and earlist sowing at April 1 with 20% increase compared to that of non mulching at April 1 planting.

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First Record of the Atka Mackerel, Pleurogrammus monopterygius(Hexagrammidae: Scorpaeniformes) from Korea (한국산 임연수어속(쥐노래미과) 어류의 1미기록종, Pleurogrammus monopterygius)

  • Youn, Chang-Ho;Kim, Byung-Jik
    • Korean Journal of Ichthyology
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    • v.12 no.4
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    • pp.250-253
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    • 2000
  • Pleurogrammus monopterygius was first collected from Daejin-ri, Goseong-gun, Gangwon-do, Korea on April 1999. This species is distinguished from its related species by having four to five broad blackish bands on the side of its body and different patterns of lateral lines. We gave P. monopterygius the new Korean name, "Dan-Gi-Im-Yon-Soo-Eo" and described the species in detail based on the study of specimens.

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