• 제목/요약/키워드: 흑색종

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Genotype Analysis of the Major Histocompatibility Complex Region in Korean Native Chicken (한국 재래닭의 MHC 영역 유전자형 분석)

  • Jung, Kie-Chul;Hoque, Md. Rashedul;Seo, Dong-Won;Park, Byung-Kwon;Choi, Kang-Duk;Lee, Jun-Heon
    • Korean Journal of Poultry Science
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    • v.36 no.4
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    • pp.317-322
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    • 2009
  • The chicken major histocompatibility complex (MHC) is known to be associated with disease resistance and susceptibility to several pathogens. The microsatellite marker LEI0258 is physically located between the BG and BF of MHC region and variations near this marker have been well documented. In this report, the LEI0258 marker was used to find specific alleles for the Korean native chicken. The MHC haplotype was analyzed by PCR screening and sequencing of LEI0258 region in four different breeds including black Korean native chicken, brown Korean native chicken, Cornish and Rhode island red. The serologically same MHC haplotypes showed the differences in repeat numbers, a few indels or single nucleotide polymorphisms by sequencing analysis. Even though we could not identify specific alleles for Korean native chickens, the genotypes analyzed in these breeds can give valuable information for the relationships with disease resistance and establishment of breeding strategies for the Korean native chicken.

Clinical Experiences of the Orbital Tumors (안와종양의 임상경험)

  • Lee, Kyung-Ha;Chung, Wha-Sun
    • Journal of Yeungnam Medical Science
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    • v.13 no.1
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    • pp.78-85
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    • 1996
  • The authors reviewed 95 cases(46 men and 49 women) of the orbital tumors diagnosed histopathologically at the Department of Ophthalmology, Yeungnam University Hospital from March 1984 through August 1994. Seventy-five cases of benign tumors were found evenly in all decades, but twenty cases of malignant tumors were noticed more frequently in 1st, 6th, and 7th decades. The frequency of benign orbital tumors was in this order; dermolipoma(21%, 20 cases), dermoid cyst(11.6%, 11 cases), mucocele(8.4%, 8 cases), lipoma(7.4%, 7 cases) and pleomorphic adenoma(5.3%, 5 cases). Of malignant orbital tumors, the frequency was in this order; retinoblastoma(3 cases), malignant melanoma(2 cases), sebaceous carcinoma(2 cases), and maxillary sinus carcinoma(2 cases). Malignant orbital tumors of 8 expired patients were revealed as secondary or metastatic tumors.

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First Occurrence of a Juvenile Halfband Cardinalfish, Apogon semiornatus (Apogonidae: Perciformes) from Jeju Island, Korea (제주도 연안에서 처음 출현한 동갈돔과 유어 Apogon semiornatus)

  • Kim, Byung-Jik;Park, Tae Seo
    • Korean Journal of Ichthyology
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    • v.24 no.3
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    • pp.227-229
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    • 2012
  • Based on a single juvenile specimen (20.7 mm SL) collected from Jeju Island, Apogon semiornatus was described as a new Korean record. The species is characterized by having VI-I, 9 dorsal fin rays, 12 pectoral fin rays; II, 8 anal fin rays and two blackish oblique bands on yellowish red body. A new Korean name, "Geom-eun-du-jul-bulg-eun-dong-gal-dom", is proposed.

Characteristics of an imperfect fungus, Microsporum nigricans Yeeh sp. nov. (불완전 진균 Microsporum nigricans Yeeh sp.nov의 특성)

  • Yeeh, Yeehn
    • Korean Journal of Microbiology
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    • v.23 no.4
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    • pp.248-251
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    • 1985
  • An imperfect fungus recognized as a dermatophyte was isolated from soil samples and the macroscopic, microscopic and physiological characteristics were examined. From the comparisons of this isolate with the known species, the strain belonged to the genus Microsporum. She showed mant different characteristics from the related species, including colony color and shape, or number in a cell of macrocondium. This isolate was considered to be a novel species in the genus Microsporum. Therefore the name was given to her as Microsporum nigricans Yeeh sp. nov. because of dark blackish color from the macroscopic observation.

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Antioxidative Effect and Melanogenesis of Nelumbo nucifera Stamen Extract on Cultured Human Skin Melanoma Cells Injured by Hydrogen Peroxide (연꽃수술추출물이 과산화수소로 손상된 배양 인체피부흑색종세포에 대한 항산화효과 및 멜라닌화에 미치는 영향)

  • Kim, Myoung-Seoup;Park, Yun-Jum;Sohn, Young-Woo
    • Korean Journal of Plant Resources
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    • v.23 no.2
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    • pp.145-150
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    • 2010
  • To examine the antioxidative effect and melanogenesis of Nelumbo nucifera stamen (NNS) extract on hydrogen peroxide $H_2O_2$ induced cytotoxicity in cultured human skin melanoma cells (SK-MEL-3), cell adhesion activity (CAA), tyrosinase inhibitory activity and total amount of melanin synthesis were measured by colorimetric assay. In this study, $H_2O_2$ significantly decreased CAA, and $CAA_{50}$ value of $H_2O_2$ was determined at 30 uM. In the antioxidative effect, NNS extract increased cell adhesion activity which was decreased by $H_2O_2$ induced cytotoxicity, and also, tyrosinase activity and total amount of melanin were decreased by NNS extract. These results suggested that $H_2O_2$ was highly toxic on cultured human skin melanoma cells and NNS extract showed the antioxidative and inhibitory effect of melanogenesis by the increased CAA, and the decresed tyrosinase activity and total amount of melanin synthesis.

Clinical Application of $^{18}F-FDG$ PET in Nonmelanomatous Skin Cancer (비흑색종 피부암에서 $^{18}F-FDG$ PET의 임상 이용)

  • Yoon, Joon-Kee
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.149-152
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    • 2008
  • Nonmelanomatous skin cancer includes basal cell carcinoma, squamous cell carcinoma, merkel cell carcinoma and dermatofibrosarcoma protuberance. So far, there have been a few reports that $^{18}F-FDG$ PET was useful in the evaluation of metastasis and therapeutic response in nonmelanomatous skin cancer, however, those are very weak evidences. Therefore, further studies on the usefulness of $^{18}F-FDG$ PET in nonmelanomatous skin cancer are required.

A New Species of the Genus Sebasles (Pisces: Scorpaenidae) from the Yellow Sea, Korea (황해에서 채집된 볼낙속(양볼낙과) 어류 1신종)

  • 김익수;이완옥
    • The Korean Journal of Zoology
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    • v.37 no.3
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    • pp.409-415
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    • 1994
  • 황해 중부의 2-30m 깊이의 연안 암초지대에서 채집된 Sebastes속 어류는 등지느러미의 극조가 14개이고, 측선공이 30-31개이며, 가슴지느러미 기부와 협부에 흑색 반점이 없어 볼낙속의 다른 유연종과는 잘 구별되었다. 본 조사에서 채집된 10개체의 표본을 기준으로 신종 Sebastes koreanus n. sp.로 기재하고, 국명은 "황해볼낙"으로 명명한다.t;으로 명명한다.

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Development of Anticancer Agents from Korean Medicinal Plants(Part 10). The Growth-inhibitory Effect of Taraxaci Herba Extract Against Human Skin Melamoma Cells (한국산 생약으로부터 항암물질의 개발(제 10보). 인체 피부흑색종세포에 대한 포공영 추출물의 성장억제효과)

  • 한두석;추광문;김영일;이종섭;유일수;오인교;강길웅;백승화
    • Toxicological Research
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    • v.14 no.4
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    • pp.489-494
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    • 1998
  • In the present study, we have evaluated cytotoxic effects of Taraxaci Herba extract on human skin melanoma cells. The light microscopic study showed morphological changes AG-NOR (argyrophylic nucleolar organizer region) by silver chloride stain, and glycoprotein by PAS reaction of the treated cells. Disruptions in cell organelles were determined by SRB assay.

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Effect of Different Colored Polyethylene Mulch on the Change of Soil Temperature and Yield of Chinese Cabbage in Autumn Season (비닐멀칭 색상이 토양온도 변화와 가을배추 수량에 미치는 영향)

  • Yun, Hong-Bae;Lee, Jong-Sik;Lee, Ye-Jin;Kim, Myung-Sook;Lee, Yong-Bok
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.4
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    • pp.511-514
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    • 2012
  • Polyethylene mulches have been used for weed control in vegetable production in Korea. One of the additional benefits associated with polyethylene mulches is soil warming. The objective of this study was to evaluate the effects of colored mulches on soil temperature change and Chinese cabbage yield. Mulch treatments were green (GV), black (BV), transparent (TV), and non-mulched (NM) soil. The highest soil-warming effect occurred under green mulch, and the lowest effect was found under black mulch. Daily mean values of soil temperature (10 cm depth) under GV were $2^{\circ}C$ higher than in NM soil. At midday (16:00), mean soil temperature was higher by $3.9^{\circ}C$ in GV, $3.1^{\circ}C$ in BV, and $2.1^{\circ}C$ in TV as compared to NM soil. At night (20:00-06:00), there was no significant difference in soil temperature among the treatments of different colored mulch, but soils in the mulch treatments were $2.4^{\circ}C$ higher as compared to NM soil. As compared with NM, the yield of Chinese cabbage under GV, BV, and TV were higher by 6.0, 26.0, and 12.0%, respectively.

First Record of the Black-barred Halfbeak, Hemiramphus far (Beloniformes: Hemiramphidae) from Jeju Island, Korea (제주도 북부 연안에서 출현한 학공치과 한국미기록종, Hemiramphus far)

  • Kim, Byung-Jik;An, Jung-Hyun;Lee, Seung-Hyun
    • Korean Journal of Ichthyology
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    • v.26 no.2
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    • pp.139-142
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    • 2014
  • Based on a single specimen collected from the northern coastal waters of Jeju Island, we described Hemiramphus far as the first record from Korea. The specimen shows a elongated body with a prolonged lower jaw, 13 dorsal fin rays, 11 anal fin rays, 36 predorsal scales, and silvery white body with five black bars laterally and yellowish color on posterior part of lower jaw, tips of dorsal fin and upper caudal lobe. "Geom-mu-neui-hag-gong-chi" is proposed as a new Korean name for the species.