• KOREAN POULTRY JOURNAL
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• v.34 no.9 s.395
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• pp.59-63
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• 2002

• KOREAN POULTRY JOURNAL
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• v.34 no.8 s.394
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• pp.116-119
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• 2002

• Proceedings of the Korean Aquaculture Society Conference
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• 2006.05a
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• pp.129-130
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• 2006

• The Korea Swine Journal
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• v.11 no.2 s.114
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• pp.45-49
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• 1989

식육중의 잔류물질 대책은 실제에 있어서 매우 간단한 일이다. 가축은 사육주가 만들어 준 환경속에서 주어지는 사료에 의하여 사육되어 진다. 따라서 환경을 정결히 하고 규제하는 약제가 첨가된 사료를 사용하지 않으며, 부득이 사용하였을 경우 충분한 휴약기간을 주어 가축의 잔류 문제가 발생되지 않도록 하여야......

• Proceedings of the Korean Aquaculture Society Conference
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• 2004.05a
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• pp.128-129
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• 2004

• Journal of Food Hygiene and Safety
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• v.22 no.1
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• pp.23-28
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• 2007

The residue depletion of streptomycin was investigated in the olive flounder (Paralichthys olivaceus), rockfish (Sebastes schlegeli), and red sea bream (Pagrus major) after consecutive three days treatment with dipping water at a dose of 20 g/ton water. Fishes were sampled for muscle on 1st, 2nd, 3rd, 4th, and 5th day after treatment. Streptomycin concentrations were determined by high performance liquid chromatography with tandem mass spectrometry. The recovery rates of streptomycin in muscle samples ranged from 87.2 to 102.3% and from 80.4 to 94.1% for the concentration of 0.05 mg/kg and 0.1 mg/kg, respectively. Streptomycin concentrations detected on the 1st day after treatment were 0.066, 0.058, and 0.073 mg/kg in muscles of olive flounder, rockfish, and red sea bream, respectively. At day 2, residue concentrations of all samples were believed to decrease to lower than 0.05 mg/kg, the detection limit. From results of the present study, a withdrawal period of streptomycin is proposed on 3 days after consecutive three days treatment with dipping administration at a dose of 20 g/ton water to avoid the presence of excessive residues of the edible muscles of olive flounder, rockfish, and red sea bream. The present study showed that residue concentrations of streptomycin decreased to below 0.05 mg/kg after treatment 2nd day.

• Journal of Food Hygiene and Safety
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• v.21 no.4
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• pp.244-249
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• 2006

The residue depletion of amoxicillin was investigated in the olive flounder (Paralichthys olivaceus), rockfish (Sebastes schlegeli), and red sea bream (Pagrus major) after 7 days treatment with medicated feed at a dose of 400 mg/kg bw/day. Fishes were sampled for muscle on 1st, 2nd, 3rd, 4th, and 5th day after treatment. Amoxicillin concentrations were determined by high performance liquid chromatography with fluorescence detector. The recovery rates of amoxicillin in muscle samples ranged 84.3-101.3% and 75.0-91.5% for the concentration of 0.05 mg/kg and 0.1 mg/kg, respectively. Amoxicillin concentrations detected on 1st day after treatment were 0.137, 0.131, and 0.172 mg/kg in the muscle of olive flounder, rockfish, and red sea bream, respectively. After a withdrawal of 3 days, muscle concentrations were 0.012, 0.010, and 0.017 mg/kg in the olive flounder, rockfish, and red sea bream, respectively. Amoxicillin was not detectable in muscle samples on 4 days following withdrawal of the medicated feed. From results of the present study, a withdrawal period of amoxicillin is proposed on 4 days after 7 days treatment with medicated feed at a dose of 400 mg/kg bw/day to avoid the presence of excessive residues of the edible muscles of olive flounder, rockfish, and red sea bream.

• 동물약계
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• no.76
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• pp.4-4
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• 2001

[ $\cdot$ ]동물용의약품(생균제) 관리 강화 협조 요청 $\cdot$이산화염소제제 품질관리 강화 지시 $\cdot$국가검정 동물사 소독실시 안내 $\cdot$동물약사감시 행정처분 결과 홍보 $\cdot$미량광물질 및 사료첨가제 관련 협의회 개최 $\cdot$생물학적제제 국가검정개선 검토협의회 개최 $\cdot$항생물질제제 휴약기간 재평가 협의회 참석 $\cdot$돼지콜레라 예방접종 중단을 위한 협의회 참석 $\cdot$수입 생물학적제제 검정시료 발췌 협의회 참석 $\cdot$동물용의약품등제조업및품목허가지침 개정 관련 협의회 개최

• Journal of the korean veterinary medical association
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• v.39 no.4
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• pp.351-360
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• 2003

성장촉진용 호르몬제제는 생체에서 근육단백질 합성 증가, 성장촉진 효과를 발휘하는 생리활성 물질로 정상적인 분비과정을 통하여 생성되는 천연호르몬과 화학적으로 제조된 합성호르몬으로 대별된다. 주요 육류수출국에서는 가축의 생산성 향상을 목적으로 성장촉진용 호르몬제제의 불법적인 오$\cdot$남용이 성행하여 식육중에 잔류되는 문제를 일으키고 있다. 축산물중 성장촉진용 호르몬 제제의 잔류방지를 위해서는 축산현장에서 사용되는 동물용 의약품의 용법, 용량을 정확히 지키고 휴약기간을 준수하는 자세가 관건이며 이를 위하여 수의사의 적극적인 계도와 홍보가 절실히 필요하다.

• Journal of fish pathology
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• v.19 no.2
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• pp.155-164
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• 2006

Tissue distribution and residue depletion of oxytetracycline (OTC) and tetracycline (TC) following dipping administration were evaluated in olive flounder (Paralichthys olivaceus), rockfish (Sebastes schlegeli), and red sea bream (Pagrus major) under field conditions. Fishes were held in floating cages placed in sea water and fed a commercial diet for 15 days to acclimate to a new surrounding. Fishes were dipped in OTC 50 g/ton water for 30min and TC 18 g/ton water for 5 hours. Blood and muscle were sampled from fishes on 0th, 1th, 2th, 3th, and 5th day after administration. After solid-phase extraction, OTC and TC analyses were carried out by HPLC. The recovery rate of OTC in serum and muscle samples was 71-77% and 78-84%, respectively. Also, the recovery rate of TC in serum and muscle samples was 70-79% and 73-78%, respectively. The results of recovery rate were similar to previous studies reported. At the termination of dipping administration of OTC and TC, residue concentration in muscle samples of rockfish was significantly higher than those of olive flounder and red sea bream. At day 5, residue concentrations of all samples were believed to decrease to lower than 0.05 mg/kg, the detection limit. The present study showed that residue concentrations of OTC and TC decreased to below 0.05 mg/kg after treatment 5th day, faster than the established withdrawal period. The tissue reside depletion time of dipping administration of OTC and TC seems to be shorter than those of oral or parenteral administration.