• Journal of Chest Surgery
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• v.32 no.7
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• pp.653-659
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• 1999

Background: Despite the recent promising efforts to improve survival in patients with esophageal carcinoma, the long term survival results of patients with esophageal cancer have seldom been reported in Korea. To establish standard control for future studies, we re trospectively analyzed the surgical treatment results of the esophageal cancer patients managed in our department at Seoul National University Hospital. Material and Method: From January 1984 to December 1996, 734 patients were diagnosed with esophageal cancer. Among them, 253 patients underwent surgery in our department. We retrospectively analyzed the operative results and long term survival rates of these patients. Result: The majority of patients(237) had squamous cell histology and only 6 patients had adenocarcinoma. The final TNM stage grouping for these patients was based on the 1988 revised American Joint Commitee on Cancer classification. Twenty one patients were surgically classified as stage I, 109 as stage II, and 107 as stage III. C respiratory failure in 8, sepsis in 1, hepatic failure in 1, bleeding in 1 and unknown etiology in the remaining 3. The actuarial survival of 222 patients in whom the curative resection was accomplished at 1-, 2-, 3- and 5 years was 74.7${\pm}$3.1%, 46.5${\pm}$3.7%, 32.3${\pm}$3.7%, and 19.9${\pm}$3.3%, respectively. CONCLUSION: The poor long term survival rates suggest that an alternative treatment method such as intensive combined modality therapy should be developed for the management of esophageal cancer.

• Journal of Life Science
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• v.24 no.9
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• pp.1025-1029
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• 2014

Cervical carcinoma is the second leading cause of cancer-related deaths in women around the world, and it is associated with the Human Papillomavirus (HPV) infection. HPV genotyping is important for vaccine policy, etiology, natural history, and epidemiology studies. The use of formalin-fixed paraffin-embedded (FFPE) tissues for HPV genotyping by reverse blot hybridization assays (REBA) has not been clearly confirmed in retrospective studies. The aim of this study was to evaluate the usefulness and efficiency of FFPE tissues from cervical cancers for HPV genotyping. HPV genotypes were detected in 52 FFPE tissues from cervical carcinoma specimens by REBA. HPV was detected in 32 (61.5%) of 52 specimens from FFPE, among which 27 (84.4%) harbored single infections and 5(15.6%) contained multiple infections. The HPV single infections (27) were analyzed by high-risk type 18(8), 58(6), 16(5), 33(1), 35(1), 39(1), 56(1) and low risk type 11(2), 6(1), 70(1). The HPV multiple infections (5) included 16/18(2), 18/52(1), 16/56(1), 16/18/33(1). Please consider being more specific here. Do you mean the analysis? Please clarify what you mean by "included."Through this study, it has been determined that the FFPE specimen is feasible and can be used in HPV genotyping, as well as in retrospective studies.

• Korean Journal of Psychosomatic Medicine
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• v.30 no.2
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• pp.165-171
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• 2022

Objectives : This study was conducted to investigate the effect of 1-year administration of second-generation antipsychotics (SGAs) on the platelet activity in patients with schizophrenia through a retrospective review of the medical records. Methods : The mean platelet component (MPC) value was used as an index of the platelet activity. The included subjects (N=24) were the patients who were confirmed to have taken SGAs continuously for one year after the first MPC measurement had been performed. The change of MPC was verified through a paired sample t-test. Results : The result revealed that the mean MPC value was significantly decreased from 26.5±1.4 g/dL to 25.6±1.8 g/dL after 1-year administration of SGAs from the time of the first MPC measurement. Conclusions : This study suggests that 1-year administration of SGAs may be related with increased platelet activity, and that close monitoring for risks such as cerebrovascular/cardiovascular or thromboembolic diseases may be necessary during SGAs treatment in clinical practice.

• Journal of the korean academy of Pediatric Dentistry
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• v.50 no.1
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• pp.24-34
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• 2023

The aim of this study was to retrospectively analyze the effects of pulp treatment on exfoliation of primary teeth and its related factors. In this study, 167 teeth of 97 patients aged 6 months to 12 years who were treated with pulp treatment at Dankook Dental Hospital were selected, and information related to pulp treatment and tooth loss was collected. The included subjects were 72 primary anterior teeth (43.1%) and 95 primary posterior teeth (56.9%), of which 56 were males (57.7%) and 41 females (42.3%). The mean follow-up period was 106.1 ± 38.7 months, and the mean age at pulp treatment was 34.8 ± 15.4 months for primary anterior teeth and 69.1 ± 25.1 months for primary posterior teeth. Unilaterally pulpectomized teeth were significantly exfoliated earlier than the same tooth on the opposite side (p < 0.05). Also, in the case of teeth with periapical lesions, despite pulp treatment, the probability of extraction due to infection has been increased on primary anterior teeth (p < 0.05), but not on posterior teeth (p > 0.05). Pulpectomized teeth were lost earlier, an average of 7.8 months for primary anterior teeth and 8.5 months for primary posterior teeth. Early loss of the primary tooth can lead to space loss and premature eruption of the successor, so this can be considered when planning or performing treatment of the primary tooth.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.2
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• pp.113-124
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• 2023

Purpose. The purpose of this study is to help increase the success rate by analyzing the types and characteristics of implant prosthesis and the survival rate. Materials and methods. Among implants placed between 2011 and 2020 at Sanbon Dental Hospital, College of Dentistry, Wonkwang University, a case restored by a prosthetic surgeon was investigated for the characteristics and correlation of failure. The causes of failure were classified as failure of osseointegration, peri-implantitis, fixture fracture, abutment fracture, screw fracture, screw loosening, prosthesis fracture, and loss of prosthesis retention. Prosthetic method, cantilever presence, placement location, etc. were analyzed for their correlation with implant failure. Results analysis was derived through Chi-square test and Kaplan-Meier survival analysis using SPSS ver 25.0 (IBM, Chicago, IL, USA). Results. A total of 2587 implants were placed, of which 1141 implants were restored with Single Crown and 1446 implants with Fixed Partial Denture, and the cumulative survival rate was 88.1%. The success rate of SC was 86.2% (984) and the success rate of FPD was 89.6% (1295), showing statistically significant differences, among which factors that had significant differences were abutment fracture, screw fracture, and screw loosening (P < .05). Conclusion. As a result of the 10-year follow-up, more failures occurred due to biomechanical factors than biological factors. Further studies on the success of implants will be needed in the future.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.8
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• pp.112-119
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• 2002

Three dimensional numerical heat transfer analysis was carried out against periodically arranged fuel injectors of the liquid rocket engine. A finite volume method based on SIMPLE algorithm was adapted which gave a good agreement with the published results of the heat transfer problem of a backward facing step. The Nusselt number and pressure drop increased as the distance between the injector elements decreased. When the Reynolds number increased, the Nusselt number increased but nondimensionalized pressure drop decreased slightly.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.33 no.11
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• pp.57-64
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• 2005

Large Eddy Simulation (LES) of turbulent premixed combustion flow is performed by using the dynamic subgrid scale model based on -equation describing the flame front propagation. After introducing the LES governing equations with dynamic subgrid scale (DSGS) model newly introduced into the -equation, the turbulent premixed combustion flow over backward facing step is analyzed to validate present formulation. The calculated results can predict the velocity and temperature of the combustion flow in good agreement with the experiment data.

• The Journal of Internal Korean Medicine
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• v.41 no.1
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• pp.69-80
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• 2020

Objective: The aim of this study was to report the improvement of stroke symptoms in patients using Mokdanpisaback-san. Methods: This study was carried out on patients hospitalized at the Department of Korean Internal Medicine of Jecheon Korean Medicine Hospital of Semyung University from October 2014 to September 2019. A retrospective study was performed on 43 patients who were diagnosed with stroke and Soyangin and treated with Mokdanpisaback-san. Results & Conclusion: 1. Mokdanpisaback-san is effective in improving various symptoms of stroke, including dysarthria, dysphagia, movement disorder, paresthesia, quadriplegia, and dizziness. 2. Mokdanpisaback-san significantly improves the motor disorders of stroke, including lower extremity muscle strength, standing, and walking disorders. 3. Mokdanpisaback-san does not affect the liver or kidney function.

• Journal of Veterinary Clinics
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• v.27 no.4
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• pp.386-391
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• 2010

This retrospective study was performed in 40 cases of canine crystalluria and urinary tract symptoms. Breed, age, sex, diet history and common clinical signs were investigated for patient information. CBC, serum chemistry, urinalysis, urine culture, urine sediment and urinary stone analysis were undertaken for clinicopathological diagnosis. Crystalluria and urinary tract symptoms occurred from 6 months till 14 years in this clinical investigation and the average age was 4.68 years. It had taken an average 7.4 weeks to correct crystalluria and urinary tract symptoms treated by supportive therapy and dietary management. In conclusion, regular clinical pathologic examination, treatment and diet management should be needed to prevent the formation of urolithiasis and urinary tract diseases in dogs with crystalluria and urinary tract symptoms.

• Journal of Intelligence and Information Systems
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• v.4 no.1
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• pp.89-102
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• 1998

본 논문에서는 저장조 설계에 필요한 설계용 입력데이타의 자동생성을 위한 지식베이스 구축과 그래픽 사용자 인터페이스를 개발하였다. 지식베이스는 전문가의 오랜 경험을 통해 축적된 지식을 전문가의 도움을 받아 객체지향 모델링 기법들을 이용하여 구축하였으며, 추론기법은 전문가시스템 내에 전향추론 기법과 후향추론 기법을 모두 갖고서 사용자와 지식베이스간의 인터페이스와 사용자가 쉽게 시스템을 사용할 수 있게 하기 위하여 윈도우 환경에서 그래픽 사용자 인터페이스를 개발하였다. 이렇게 개발된 전문가시스템을 과거 수행했던 저장조 설계 프로젝트에 적용해 봄으로써, 비전문가도 전문가의 도움 없이 저장조를 설계할 수 있었으며, 표준화된 절차에 의하여 설계함으로써 설계상의 오류를 줄일 수 있었고, 약 88%의 비용을 감소시킬 수 있었다.