• Journal of radiological science and technology
• /
• v.32 no.3
• /
• pp.299-306
• /
• 2009

Purpose : To compare radiation dose for coronary CT angiography (CTA) obtained with 6 examination protocols such as a retrospectively ECG gated helical scan, a prospectively ECG gated sequential scan, low kVp technique, and cardiac dose modulation technique. Materials and Methods : Coronary CTA was performed by using 6 current clinical protocols to evaluate effective dose and organ dose in primary beam area with anthropomorphic female phantom and glass dosimetric system in 64 channel multi-detector CT. After acquiring topograms of frontal and lateral projection with 80 kVp and 10 mA, main coronary scan was done with 0.35 sec tube rotation time, 40 mm collimation ($0.625\;mm{\times}64\;ea$), small scan field of view (32 cm diameter), 105 mm scan length. Heart beat rate of phantom was maintained 60 bpm in ECG gating. In constant mAs technique 120 kVp, 600 mA was used, and 100 kVp for low kVp technique. In a retrospectively ECG gated helical CT technique 0.22 pitch was used, peak mA (600 mA) was adopted in range of $40{\sim}80%$ of R-R interval and 120mA(80% reduction) in others with cardiac dose modulation. And 210 mAs was used without cardiac dose modulation. In a prospectively ECG gated sequential CT technique data were acquired at 75% R-R interval (middle diastolic phase in cardiac cycle), and 120 msec additional padding of the tube-on time was used. For effective dose calculation region specific conversion factor of dose length product in thorax was used, which was recommended by EUR 16262. Results : The mean effective dose for conventional coronary CTA without cardiac dose modulation in a retrospectively ECG gated helical scan was 17.8 mSv, and mean organ dose of heart was 103.8 mGy. With low kVp and cardiac dose modulation the mean effective dose showed 54.5% reduction, and heart dose showed 52.3% reduction, compared with that of conventional coronary CTA. And at the sequential scan(SnapShot pulse mode) under prospective ECG gating the mean effective dose was 4.9 mSv, this represents an 72.5% reduction compared with that of conventional coronary CTA. And heart dose was 33.8 mGy, this represents 67.4% reduction. In the sequential scan technique under prospective ECG gating with low kVp the mean effective dose was 3.0 mSv, this represents an 83.2% reduction compared with that of conventional coronary CTA. And heart dose was 17.7 mGy, this represents an 82.9% reduction. Conclusion : In coronary CTA at retrospectively ECG gated helical scan, cardiac dose modulation technique using low kVp reduced dose to 50% above compared with the conventional helical scan. And the prospectively ECG gated sequential scan offers substantially reduced dose compared with the traditional retrospectively ECG gated helical scan.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.15 no.1
• /
• pp.17-24
• /
• 2011

Purpose: Presently in the nuclear medicine field, the high-speed image reconstruction algorithm like the OSEM algorithm is widely used as the alternative of the filtered back projection method due to the rapid development and application of the digital computer. There is no to relate and if it applies the optimal parameter be clearly determined. In this research, the quality change of the Jaszczak phantom experiment and brain SPECT patient data according to the iteration times and subset number change try to be been put through and analyzed in 3D OSEM reconstruction method of applying 3D beam modeling. Materials and Methods: Patient data from August, 2010 studied and analyzed against 5 patients implementing the brain SPECT until september, 2010 in the nuclear medicine department of ASAN medical center. The phantom image used the mixed Jaszczak phantom equally and obtained the water and 99mTc (500 MBq) in the dual head gamma camera Symbia T2 of Siemens. When reconstructing each image altogether with patient data and phantom data, we changed iteration number as 1, 4, 8, 12, 24 and 30 times and subset number as 2, 4, 8, 16 and 32 times. We reconstructed in reconstructed each image, the variation coefficient for guessing about noise of images and image contrast, FWHM were produced and compared. Results: In patients and phantom experiment data, a contrast and spatial resolution of an image showed the tendency to increase linearly altogether according to the increment of the iteration times and subset number but the variation coefficient did not show the tendency to be improved according to the increase of two parameters. In the comparison according to the scan time, the image contrast and FWHM showed altogether the result of being linearly improved according to the iteration times and subset number increase in projection per 10, 20 and 30 second image but the variation coefficient did not show the tendency to be improved. Conclusion: The linear relationship of the image contrast improved in 3D OSEM reconstruction method image of applying 3D beam modeling through this experiment like the existing 1D and 2D OSEM reconfiguration method according to the iteration times and subset number increase could be confirmed. However, this is simple phantom experiment and the result of obtaining by the some patients limited range and the various variables can be existed. So for generalizing this based on this results of this experiment, there is the excessiveness and the evaluation about 3D OSEM reconfiguration method should be additionally made through experiments after this.

• Journal of radiological science and technology
• /
• v.34 no.4
• /
• pp.341-349
• /
• 2011

This study was to measure the patient dose difference between 3D treatment planning CT and 4D respiratory gating CT. Study was performed with each 10 patients who have lung and liver cancer for measured patient exposure dose by using SOMATON SENSATION OPEN(SIMENS, GERMANY). CTDIvol and DLP value was used to analyze patient dose, and actual dose was measured in the location of liver and kidney for abdominal examination and lung, heart and spinal cord for chest examination. Rando phantom were used for the experiment. OSLD was used for in-vitro and in-vivo dosimetry. Increasing overall actual dose in 4D respiratory gated CT-simulation using OSLD increase the dose by 5.5 times for liver cancer patients and 6 times for lung cancer patients. In CT simulation of 10 lung cancer patients, CTDIvol value was increased by 5.7 times and DLP 2.4 times. For liver cancer patients, CTDIvol was risen by 3.8 times and DLP 1.6 times. The accuracy of treatment volume could be increased in 4D CT planning for position change due to the breaths of patient in the radiation therapy. However, patients dose was increased in 4D CT than 3D CT. In conclusion, constant efforts is required to reduce patients dose by reducing scan time and scan range.

• The Korean Journal of Nuclear Medicine
• /
• v.30 no.4
• /
• pp.548-559
• /
• 1996

A series of performance measurements of positron emission tomography (PET) were performed following the recommendations of the Computer and Instrumentation Council of the Society of Nuclear Medicine and the National Electrical Manufacturers Association. We investigated the performance of the General Electric $Advance^{TM}$ PET. The measurements include the basic intrinsic tests of spatial resolution, scatter fraction, sensitivity, and count rate losses and randoms. They also include the tests of the accuracy of corrections: count rate linearity correction, uniformity correction, scatter correction and attenuation correction. GE $Advance^{TM}$ PET has bismuth germanate oxide crystals (4.0mm transaxial ${\times}$ 8.1mm axial ${\times}$ 30.0mm radial) in 18 rings, which form 35 imaging planes spaced by 4.25mm. The system has retractable tungsten septa 1mm thick and 12cm long. Transaxial resolution was 4.92mm FWHM in 2D and 5.14mm FWHM in 3D at the center. Average axial resolution in 2D decreased from 3.91mm FWHM at the center to 6.49mm FWHM at R=20cm. Average scatter fraction of direct and cross slices was 9.57%. Dead-time losses of 50% corresponded to a radioactivity concentration of $4.86{\mu}Ci/cc$ and a true count rate of 519 kcps in 2D. The accuracy of count rate linearity correction was 1.84% at the activity of $4.50{\mu}Ci/cc$. Non-uniformity was 2.06% in 2D and 2.93% in 3D. Remnant errors after scatter correction were 0.55% in 2D and 4.12% in 3D. The errors of attenuation correction were 6.21% (air), 0.20% (water), -6.32% (teflon) in 2D and 5.00% (air), 6.94% (water), 3.01% (teflon) in 3D. The results indicate the performance of GE $Advance^{TM}$ PET scanner to be well suited for clinical and research applications.

• Nuclear Medicine and Molecular Imaging
• /
• v.43 no.5
• /
• pp.468-477
• /
• 2009

Purpose: Hydrodynamic-based procedure is a simple and effective gene delivery method to lead a high gene expression in liver tissue. Non-invasive imaging reporter gene system has been used widely with herpes simplex virus type 1 thymidine kinase (HSV1-tk) and its various substrates. In the present study, we investigated to image the expression of HSV1-tk gene with 5-(2-iodovinyD-2'-deoxyuridine (IVDU) in mouse liver by the hydrodynamicbased procedure. Materials and Methods: HSV1-tk or enhanced green fluorescence protein (EGFP) encoded plasmid DNA was transferred into the mouse liver by hydrodynaminc injection. At 24 h post-injection, RT-PCR, biodistribution, fluorescence imaging, nuclear imaging and digital wholebody autoradiography (DWBA) were performed to confirm transferred gene expression. Results: In RT-PCR assay using mRNA from the mouse liver, specific bands of HSV1-tk and EGFP gene were observed in HSV1-tk and EGFP expressing plasmid injected mouse, respectively. Higher uptake of radiolabeled IVDU was exhibited in liver of HSV1-tk gene transferred mouse by biodistribution study. In fluorescence imaging, the liver showed specific fluorescence signal in EGFP gene transferred mouse. Gamma-camera image and DWBA results showed that radiolabeled IVDU was accumulated in the liver of HSV1-tk gene transferred mouse. Conclusion: In this study, hydrodynamic-based procedure was effective in liver-specific gene delivery and it could be quantified with molecular imaging methods. Therefore, co-expression of HSV1-tk reporter gene and target gene by hydrodynamic-based procedure is expected to be a useful method for the evaluation of the target gene expression level with radiolabeled IVDU.

• Journal of Wetlands Research
• /
• v.19 no.3
• /
• pp.318-326
• /
• 2017

Riverine wetlands were reduced and damaged by dredging of rivers and constructing parks in wetlands by Four Rivers Project from 2008 to 2013. Therefore, replacement wetlands were constructed for the compensation of wetland loss by the government. However, It is not enough to manage replacement wetlands. In order to manage the wetlands efficiently, it is necessaty to assess the functions of the wetlands and to manage them according to their functions. Here we performed functional assessments for a replacement wetland called Gangcheon wetland using the modified HGM approach. Hydrological, biogeochemical, animal habitat, and plant habitat functions for the wetland were assessed. To assess the functions, we collected informations for modified HGM approach from the monitored hydrologic data, field survey, published reports and documents for before and after the project, and hydraulic & hydrologic modeling. As the results of the assessment, the hydrological function for the replacement wetland showed 65.5% of the reference wetland, biogeochemical function showed 66.6%, plant habitat function showed 75%, and animal habitat function showed 108.3%. Overall, Gangcheon wetland function after the project was reduced to 78.9% of the function before the project. The decrease in hydrological function is due to the decrease of subsurface storage of water. And the decrease in biogeochemical & pland habitat functions is due to the removal of sandbank around the Gangcheon wetland. To compensate for the reduced function, it is necessary to expand the wetland area and to plant the various vegetation. The modified HGM used in this study can take into account the degree of improvement for replacement wetlands, so it can be used to efficiently manage the replacement wetlands. Also when the wetland is newly constructed, it will be very useful to assess the change of function of the wetland over time.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2005.06a
• /
• pp.311-318
• /
• 2005

Transparency on the Total System Performance Assessment (TSPA) is the key issue to enhance the public acceptance for a permanent high level radioactive repository. To approve it, all performances on TSPA through Quality Assurance is necessary. The integrated Cyber R&D Platform is developed by KAERI using the T2R3 principles applicable for five major steps in R&D's. The proposed system is implemented in the web-based system so that all participants in TSPA are able to access the system. It is composed of FEAS (FEp to Assessment through Scenario development) showing systematic approach from the FEPs to Assessment methods flow chart, PAID (Performance Assessment Input Databases) showing PA(Performance Assessment) input data set in web based system and QA system receding those data. All information is integrated into Cyber R&D Platform so that every data in the system can be checked whenever necessary. For more user-friendly system, system upgrade included input data & documentation package is under development. Throughout the next phase R&D, Cyber R&D Platform will be connected with the assessment tool for TSPA so that it will be expected to search the whole information in one unified system.

• Archives of design research
• /
• v.16 no.1
• /
• pp.181-198
• /
• 2003

The purpose of this study is to develop a on-line design tool for effectively coping with e-Business environment, or product design process into a Cyber model for traditional manufacturers which attempts new product development under such environment. It was finally developed as a model named $\ulcorner$Design Vortal Site; e-BVDS) that was based on the structure and style of internet web site. Results of the study can be described as follows ; \circled1 e-Business is based on the Internet. All processes in the context of e-Business require models whose structure and method of use are on-line styles. \circled2 In case that a traditional manufacturing business is converted into e-Business, it is better to first consider Hybrid Model that combines resources and advantages of both such traditional and digital businesses. \circled3 The product design process appropriate for e-Business environment has to have a structure and style that ensure utilization of the process as an Internet web site, active participation by product developers and interactive communication between participants in designing and designers. \circled4 $\ulcorner$e-BDVS) makes possible the use of designers around the wend like in-house designers, overcoming lack in creativity, ideas and human resources traditional business organizations face. However, the operation of $\ulcorner$e-BDVS$\lrcorner$ requires time and budget investments in securing related elements and conditions. \circled5 Cyber designers under $\ulcorner$e-BDVS$\lrcorner$ can easily perform all design projects in cyber space. But they have some limits in playing a role as designers and they have difficulty in getting rewards if such projects completed by them are not finally accepted. \circled6 $\ulcorner$e-BDVS) ensures the rapid use of a wide range of design information and data, reception of a variety of solutions and ideas and effective design development, all of which are not possible through traditional processes. However, this process may not be suitable to be used routine process or tool. \circled7 $\ulcorner$e-BDVS$\lrcorner$ makes it possible for out-sourcing or partners businesses to overcome restrictions in time and space and improve productivity and effectiveness. But such they may have to continue off-line works that can not be treated on-line.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.34 no.1
• /
• pp.43-52
• /
• 2016

Due to the characteristics of microwave signals, Radar satellite image has been used for flood detection without weather and time influence. The more methods of flood detection were developed, the more detection rate of flood area has been increased. Since flood causes a lot of damages, flooded area should be distinguished from non flooded area. Also, the detection of flood area should be accurate. Therefore, not only image resolution but also the filtering process is critical to minimize resolution degradation. Although a resolution of radar images become better as technology develops, there were a limited focused on a highly suitable filtering methods for flood detection. Thus, the purpose of this study is to find out the most appropriate filtering method for flood detection by comparing three filtering methods: Lee filter, Frost filter and NL-means filter. Therefore, to compare the filters to detect floods, each filters are applied to the radar image. Comparison was drawn among filtered images. Then, the flood map, results of filtered images are compared in that order. As a result, Frost and NL-means filter are more effective in removing the speckle noise compared to Lee filter. In case of Frost filter, resolution degradation occurred severly during removal of the noise. In case of NL-means filter, shadow effect which could be one of the main reasons that causes false detection were not eliminated comparing to other filters. Nevertheless, result of NL-means filter shows the best detection rate because the number of shadow pixels is relatively low in entire image. Kappa coefficient is scored 0.81 for NL-means filtered image and 0.55, 0.64 and 0.74 follows for non filtered image, Lee filtered image and Frost filtered image respectively. Also, in the process of NL-means filter, speckle noise could be removed without resolution degradation. Accordingly, flooded area could be distinguished effectively from other area in NL-means filtered image.

• The Journal of Engineering Geology
• /
• v.26 no.2
• /
• pp.277-290
• /
• 2016

Deep geological cross-sectional data is generally not common nor easy to construct, because it is expensive and requires a great deal of time. As a result, geological interpretations at depth are limited. Many scientists attempt to construct geological cross-sections at depth using geological surface data and geophysical data. In this paper, we suggest a method for constructing cross-sections from limited geological surface data in a target area. The reason for this study is to construct and interpret geological cros-sections at depth to evaluate heat flow anomaly along the Yangsan fault. The Yangsan Fault passes through the south-eastern part of the Korean Peninsula. The cross-section is constructed from Sangbukmyeon to Unchonmyeon passing perpendicularly through the Yangsan Fault System trending NW-SE direction. The geological cross-section is constructed using the following data: (1) Lithologic distributions and main structural elements. (2) Extensity of sedimentary rock and igneous rock, from field mapping. (3) Fault dimension calculated based on geometry of exposed surface rupture, and (4) Seismic and core logging data. The Yangsan Fault System is composed of the Jain fault, Milyang fault, Moryang fault, Yangsan fault, Dongnae fault, and Ingwang fault which strike NNE-SSW. According to field observation, the western section of the Yangsan fault bounded by igneous rocks and in the eastern section sedimentary rocks are dominant. Using surface fault length we infer that the Yangsan Fault System has developed to a depth of kilometers beneath the surface. According to seismic data, sedimentary rocks that are adjacent to the Yangsan fault are thin and getting thicker towards the east of the section. In this study we also suggest a new method to recognize faults using core loggings. This analysis could be used to estimate fault locations at different scales.