A new nutritional disease has occurred among the hatchery-reared Korean bullhead fingerlings (Pseudobagrus fulvidraco) in the Chonbuk Province in September 1997. Diseased fish were all dead within 3-7 days, showing sluggish behavior, head up and tail down swimming. Most characteristic clinical signs were anaemia, clubbed and fused gill, skin desquamation. haemorrhage around the mouth and at the base of pectoral fins. Any causative bacteria and parasites were not isolated from the lesions and internal organs of the diseased fish. The hepatosomatic index, red blood cell count, hematocrit, hemoglobin and erythrocytes size of peripheral blood in the diseased fish were remarkably decreased compared with those of normal fish. In the histopathological observations, epithelial hyperplasia of the gill filaments initiated at the base of the gill was pronounced. This symptom was the characteristic appearence of all the diseased fish. A 0.6% saline bath and feeding a pantothenic acid-supplemented diet were conducted to decrease the mortality. Ten days after 0.6% saline bath or 25 days after feeding a pantothenic acid supplemented diet resulted in decreasing in the mortality. Microscopic appereance of the gill from the recovered fish was similar to that of the gill from healthy fish. These results indicate that the disease was caused by deficency of pantothenic acid in their diet and that 0.6% saline bath or supplementation of pantothenic acid in the diet was an effective way to decrease the mortality.
Backgound: Cryoablation and radiofrequency ablation have been used to treat the atrial fibrillation. Some reports insisted that the microwave ablation Is a better method for a deep and extensive lesion. Material and Method: From December 2001 to July 2002, we peformed 8 microwave ablations in patients who needed mitral valve surgery (7 MVR, 1 MVR+AVR). There were 3 men and 5 women, and their mean age was 43.4$\pm$8.3 years and mean follow up period was 5.6$\pm$2.4 months respectively. The microwave was applied on endocardium or epicardium by Lynx (Afx, inc.) using a power of 45 watts for 25 seconds. We studied the left atrial dimension, the left atrial function and the sinus conversion with echocardiography and electro-cardiography at three times; 1) before the operation, 2) immediately after the operation, and 3) 6 months after the operation. Result: There was no complication and no mortality. The mean aortic clamping time was 104.6$\pm$25.0 minutes, and the mean total bypass time was 130.5$\pm$28.7 minutes. The rate of sinus conversion was 75%, A wave across the mitral valve was a mean of 77.0$\pm$24.8 cm/sec, and the AVE was a mean of 0.46$\pm$0.17 at 5.6 months postoperatively Conclusion: There was no difference in the early result of microwave ablation compared to other methods. The microwave ablation was an acceptable method due to its convenient application especially in beating heart.
Transactions of the Korean Society of Mechanical Engineers B
/
v.34
no.12
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pp.1087-1092
/
2010
A micro 3D-PTV system has been constructed using a single camera system. Two viewing holes were created behind the object lens of the microscopic system to construct a stereoscopic viewing image. A hybrid recursive PTV algorithm was used. A concept of epipolar line was adopted to eliminate many spurious candidates. Three-dimensional velocity vector fields were obtained by calculating the three-dimensional displacements of particles that were identified as being identical. The system consists of a laser light source (Ar-ion, 500 mW), one high-definition camera ($1028{\times}1024$ pixels, 500 fps), a circular plate with two viewing holes, and a host computer. The performance of the developed algorithm was tested using artificial images. The characteristic of the vector recovery ratio was investigated for the particle numbers. A micro backward-facing step channel ($H{\times}h{\times}W:\;36{\mu}m{\times}70{\mu}m{\times}3000{\mu}m$) was measured using the developed measurement system. The results were in good qualitative agreement with other results.
Journal of the Korean Society of Propulsion Engineers
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v.23
no.5
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pp.107-114
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2019
In many military aircraft, s-shaped diffusers are used to prevent the fan blades of the turbofan engine from being exposed to the outside. The inlet configurations of the air intakes for military aircraft vary, such as the rectangular intake of the F-22, the crescent-like intake of the F-16, elliptical intake of the MQ-25. In this study, the aerodynamic performance of s-shaped diffusers with various inlet configurations was evaluated using numerical analysis. In addition, the configuration of the middle section of an s-shape duct was changed to the crescent shape, and the effects on its aerodynamic performance were investigated. As a result, there was a slight difference in total pressure recovery according to various inlet configurations with ellipse-shaped middle sections. Also, the total pressure distortion was the lowest in the rectangular inlet shape. When the configuration of the middle section was changed from an ellipse to a crescent shape, the total pressure recovery remained at a high level, except for the ellipse-shaped inlet configuration. In terms of total pressure distortion, the duct with the crescent-shaped middle section showed a significantly more uniform pressure distribution than that with the ellipse-shaped middle section.
Adequate acidic environment in wound healing prevents the inflammation of virus, increases the cell activity, promotes cell proliferation and regular rearrangement of fibroblast, and results in matured epithelialization. In this study, we prepared dressing materials consisting of pectin and carboxymethylcellulose (CMC) with varied ratios. These dressing materials showed different pH values according to the composition ratio. The effect of acidity of pectin/CMC dressing materials on wound healing rates, degree of epithelialization, collagen deposition, and so on, in 3 types of wound models (fresh surgical wounds, $3^{rd}$ degree burn wounds, and infection wounds) were investigated by animal tests. From the results of wound contraction, wound healing, and epithelialization, it can be deduced that dressing material having pectin/CMC ratio of 16/19 (pH 4.67) is most effective among the 3 types of wound models.
For comprehensively assessment the water resources performance of multi-purpose dams and water supply dams in South Korea, a methodology was proposed to utilize the durational reliability along with the integrated auxiliary indicators including resiliency, dimensionless vulnerability, water resource efficiency, specific inflow, and specific water supply. In addition, for the purpose of sustainable dam operation in the future, a plan to grade the water resources performance was presented to periodically evaluate the performance and determine the priority of each dam's structural or non-structural planning according to the evaluation results. As major results, in the case of Sumjingang Dam, the durational reliability was 99.0%, but the integrated auxiliary index was the lowest of 44 points, which was 5th grade. This means that despite the current high reliability, hydrological changes due to future climate change or regional change of water demand-supply balance can have significant impacts on the water resources performances. In contrast, the Chungju Dam with a durational reliability of 93.0%, which is below the average among all multi-purpose dams, shows the 76 points of the integrated auxiliary index, which is 3rd highest following the Soyanggang Dam and the Namgang Dam. Nevertheless, due to the size of the basin, the specific inflow is sufficiently high as 185%, so the actual performance could be evaluated relatively high. The water supply dams designed for a single purpose tend to be evaluated relatively high because they have a high proportion of industrial and municipal water supply and have enough room for the supply capacity.
In this study, we isolated Weizmannia ginsengihumi LGHNH (KCTC 14462BP) from 30-year-old wild Panax ginseng C.A. Meyer and elucidated the characteristics of the isolated bacterium and its industrial potential as an anti-aging material. W. ginsengihumi LGHNH was investigated to produce indole-3-acetic acid (IAA), a plant growth-promoting hormone (1.38 ㎍/ml to 2.22 ㎍/ml). We also confirmed the existence of bioconversion activity via the comparison of the ginsenoside content before and after fermentation. As for the converted minor ginsenoside, Rg2(R), Rg4, Rg6, Rg3(S), Rg3(R), Rk1, Rg5, Rh1(R), Rk3 and Rh4 are known to have high bioavailability and various skin effects. We measured mitochondrial membrane potential and ATP biosynthesis to elucidate W. ginsengihumi LGHNH cultured product (WCP) as an anti-aging material. As a result, the mitochondrial membrane potential in HaCaT cells with UVB decreased to 39.3% compared to the unirradiated group, but was recovered to 57.3% and 58.1% by 0.001% (v/v) and 0.01% (v/v) WCP, respectively. In addition, we measured mitochondrial ATP biosynthesis. It decreased to 94.3% compared to the unirradiated group with UVB, but was recovered to 105.3% and 105.7% by 0.001% (v/v) and 0.01% (v/v) WCP.
Journal of the Korean Applied Science and Technology
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v.41
no.3
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pp.705-720
/
2024
This study randomly assigned 24 middle-aged women to determine the effect of a 12-week combined exercise program on cardiovascular function and electrocardiogram-based ST segment and QRS in obese middle-aged women. Analysis of the results was conducted to verify differences within groups and between periods and groups. In terms of cardiovascular function, myocardial oxygen consumption showed a significant decrease in the experimental group during the resting phase and the highest intensity phase during exercise, and an interaction between group and period at rest was also observed. The heart rate recovery rate showed a significant decrease in the experimental group at 2 minutes of recovery, while in the control group, on the contrary, a significant increase was observed. The experimental group showed a significant decrease in systolic blood pressure, and an interaction between group and period was also observed. There was no change in diastolic blood pressure in both the experimental and control groups, and there was a statistically significant decrease in pulse pressure only in the experimental group at the 3-minute recovery stage. In the case of the electrocardiogram, the QRS height in the experimental group showed a significant increase in most cases at rest and at 3, 6, and 9 minutes during the recovery period, while there was no significant difference in the QRS period in both the experimental and control groups, and the ST segment height was significantly increased at rest in the experimental group. appeared to have increased. Therefore, summarizing the results of this study, it is believed that the 12-week combined exercise program has a positive effect in improving cardiovascular function, ventricular contractility in electrocardiograms, and myocardial ischemia in obese middle-aged women.
Journal of Dental Rehabilitation and Applied Science
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v.27
no.1
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pp.25-39
/
2011
In animal studies, Magnesium (Mg) - incorporated oxidized implants showed significant enhancement of the bone response. This prospective clinical trial was performed to investigate the success rate, implant stability and marginal bone loss of Mg oxidized clinical implant. The experimental protocol was approved by Institutional Review Board of the Gangneung-Wonju National University Dental Hospital. Fifty healthy patients had partial edentulism were included in this study. Mg oxidized clinical implants (Implant M, Shinhung, Korea) were installed and restored with conventional protocol. The patients were recalled at 1, 3, 6 months after functional loading. Implant stability quotient (ISQ) was measured and periapical radiographic images were obtained. Amount of marginal bone loss was calculated with calibrated images from periapical radiographs. Repeated measured analysis of variance and post hoc Tukey test were used to compare the mean ISQ and bone level. A total of 101 implants were analyzed. The mean ISQ values increased continuously with time lapse from 68.4 at fixture installation to 71.5 at 6 months after loading. Implant stability was correlated with gender, fixture diameter, bone quality and implant sites. The mean marginal bone loss during 6 months after loading was 0.26 mm. There was no failed implant and six-month success rate was 100%. Within the limitations of this study, the six-month success rate of Mg oxidized implant was satisfactory. The implant stability and marginal bone level were excellent. However, further longer clinical studies will be needed to confirm the success of Mg oxidized clinical implant.
Journal of Dental Rehabilitation and Applied Science
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v.27
no.3
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pp.267-275
/
2011
This prospective study was designed to compare clinical outcomes of immediately loaded implant with delayed loaded implant in partially posterior edentulous patients. For test group, 42 GS III (Osstem, Korea) implants in 17 patients were loaded within 48 hours after the placement. Control group was 27 implants in 15 patients loaded at $2.6{\pm}1.7months$ from the placement surgery. Before loading, primary stability was evaluated by ISQ value. Clinical symptoms, mobility, soft tissue state was evaluated at baseline, 3 months, 6 months and 12 months of loading. Marginal bone level change was also measured with periapical radiographs. Mann-Whitney test (${\alpha}$=0.05) and repeated measured ANOVA (${\alpha}$=0.05) was used for marginal bone level change between two groups. At the baseline, mean ISQ value of test group and control group was $80.3{\pm}7.1$ and $69{\pm}17$ respectively. Test group showed 95.23% of success rate and 100% of control group was successful. At 3 and 6months of loading, significantly more bone resorption was observed in test group than in control group (p<0.05). However, there was no significant difference in the bone level change at 12months of loading between two groups (p>0.05). Marginal bone level change showed no significant difference with gender and location (p>0.05). Within the limitation of this study, when primary stability was obtained, immediate loading of GS III implant at posterior region could be predictable treatment option.
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