• Title/Summary/Keyword: 회복률

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The Clinical Effects of Leukocyte-Depleting Filter on Cardiopulmonary Bypass (체외순환 시 백혈구 제거필터 사용의 임상효과)

  • 박경택;최석철;최국렬;정석목;최강주
    • Journal of Chest Surgery
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    • v.34 no.6
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    • pp.454-464
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    • 2001
  • Background: It has been recognized that systemic inflammatory reaction and oxygen free radical formed by activated leukocyte in the procedure of cardiopulmonary bypass(CPB) frequently produce postoperative cardiac and pulmonary dysfunction. The purpose of this study was to evaluate the efficacy of leukocyte-depleting filters in the cardiopulmonary bypass circuit for patients undergoing open heart surgery(OHS). Material and method: The study involved 15 patients who underwent OHS with a Leukoguard-6 leukocyte filter placed in the arterial limbs of the bypass circuit(filter group, n=15) and 15 patients who did not have the filter(control group, n=15). We analyzed the differences between the groups in intraoperative changes of peripheral blood leukocyte and platelet counts, pre- and postbypass changes of malondialdehyde(MDA), troponin-T(TnT), 5'-nucleotidase(5'-NT) in coronary sinus blood, spontaneous recovery rate of heart beat after CPB, pre-and postoperative cardiac index(Cl) and pulmonary vascular resistance(PVR), and the amounts of postoperative bleeding and sternal wound complication. Result: During CPB, total leukocyte count of the filter group(9,567$\pm$ 842/㎣) was significantly less than that of the control group(13,573+1,167/㎣) (p<0.01), but there was no significant difference in platelet count between the groups. Postoperative levels of MDA(3.78+0.32 $\mu$mol/L vs 5.86+0.65 $\mu$mo1/L, p<0.01), TnT(0.40$\pm$0.04 ng/mL vs 0.59$\pm$0.08 ng/mL, p<0.05) and 5'-NT(3.88$\pm$0.61 U/L vs 5.80$\pm$0.90 U/L, p<0.05) were all significantly lower in the filter group than the control group. Postoperative Cl was higher in the filter group than the control group(3.26$\pm$0.18 L/$m^2$min vs 2.75$\pm$0.17 L/$m^2$/min, p=0.05). PVR of the filter group was lower than that of the control group(65.87$\pm$7.59 dyne/sec/cm$^{5}$ vs 110.80+12.22 dyne/sec/cm$^{5}$ , p<0.01). Spontaneous recovery rate of heart beat in the filter group was higher than that in the control group(12 patients vs 8 patients, p<0.05). Postoperative wound infection occurred in one case in the filter group and 4 case in the control group(p<0.05). Postoperative 24 hour blood loss of the filter group was more than that of the control group (614$\pm$107 mL vs 380+71 mL, p=0.05).

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An Analysis of the Realities and Causes of Youth and New College Graduate Unemployment (청년실업과 신규대졸자 실업의 실태, 원인분석 및 과제)

  • Chai, Goo-Mook
    • Korean Journal of Social Welfare
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    • v.56 no.3
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    • pp.159-181
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    • 2004
  • This study examines the realities and causes of youth and new college graduate unemployment, and seeks some assignments for mitigating youth and new college graduate unemployment. An analysis of the realities and causes of youth and new college graduate unemployment is summarized as follows. First, youth unemployment rate, which rapidly increased after the IMF economic crisis, slowly decreased after 2000, but was still somewhat higher in 2002 than that before the IMF. Second, new college graduate unemployment rate, which rapidly increased after the IMF economic crisis, slowly decreased after 2000 and became a similar level to that before the IMF economic crisis, but the number of the unemployed new college graduates highly increased after the IMF. Third, an analysis of the causes of youth unemployment shows that economic growth and the employment elasticity of economic growth negatively affect the unemployment rate, and the rate of entrance into colleges positively affects the unemployment rate. Fourth, an analysis of the causes of new college graduate unemployment demonstrates that economic growth and the employment elasticity of economic growth negatively affect the unemployment rate, and the increase rate of new college graduates, the college graduate/youth population ratio, and the time trend positively affect the unemployment rate. These results suggest several implications for mitigating the unemployment rate of the youth and new college graduates. First, in order to increase labor demand, emphasis must be placed on preparing economic conditions which can raise economic growth rate and on fostering industries and occupations which have high employment elasticity. Second, in the aspect of labor supply, it is necessary to adjust the number of new college graduates corresponding to labor demands in industries. Third, in order to redress the mismatch between the demand and the supply of the youth labor market, attention should be paid to remedying educational systems such as the activation of vocational education and training in middle and high schools and the reformation of college education to match the education and training provided in colleges and the skills requirements of the world of work, and preparing a unified program to support the youth unemployed systematically and synthetically.

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Growth and Blood Characteristics of Red Sea Bream Pagrus major by Starvation and Stocking Density during Red Tide (적조발생시기 참돔의 절식과 사육밀도에 따른 성장과 혈액성상)

  • Kim, Won-Jin;Lee, Jeong-Yong;Shin, Yun-Kyung;Won, Kyoung-Mi
    • Korean Journal of Ichthyology
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    • v.30 no.4
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    • pp.194-204
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    • 2018
  • In order to minimize the damage on the red sea bream Pagrus major by a harmful dinoflagellate Cochlodinium polykrikoides, we investigated the effect of feeding, starvation and stocking density on the survival rate, growth, growth restoration and physiological response of P. major exposure to C. polykrikoides. The experimental groups were divided into three groups such as F-HD (feeding and high density with $6.4kg/m^3$), S-HD (starvation and high density with $6.4kg/m^3$) and S-LD (starvation and low density with $3.2kg/m^3$) according to stocking density and starvation in marine cage ($11m{\times}11m{\times}5m$). The F-HD was fed throughout the experiment for 9 weeks, whereas S-HD and S-LD were not fed for 5 weeks and then refeeding for 4 weeks. Survival rate was the lowest in F-HD (85.5%) and S-LD was the highest (97.3%). The growth rates of S-HD and S-LD were significantly lower than F-HD during starvation period for 4 weeks, but rapidly recovered after feeding. The nutritional status such as ALB, TP, TCH, TG were similar to tendency of growth data. Ht, Hb, AST, ALT and GLU levels were significantly higher in the F-HD than in the starvation groups at the same time (in 3 week) during starvation period. But starvation groups did not differ during starvation period. As a result, F-HD is more sensitive to stress than S-HD and S-LD. Thus, during C. polykrikoides bloom period, starvation and stocking density control can help survival and growth restoration of the red sea bream.

Degradation of Silicone Rubber Used as Outdoor Insulator Under Accelerated Weathering Condition (자외선 가속열화에 따른 전력용 실리콘 절연재료의 열화평가)

  • Youn, B.H.;Bai, K.M.;Lee, S.J.;Paek, J.H.;Kim, S.W.;Jeon, S.I.
    • Proceedings of the KIEE Conference
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    • 2004.07c
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    • pp.1906-1908
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    • 2004
  • 본 논문은 옥외용 고분자 절연물로 널리 사용되고 있는 실리콘 고무의 장기 자외선 가속열화에 따른 특성변화를 조사하였다. 이를 위해 전기적인 평가 방법 이외에 각종 화학적 분석기기를 사용하여 보다 정확히 재료의 열화를 판정하고자 하였다. 연구결과, 실리콘 고무는 내후성이 우수하지만, 가속열화가 진행되면서 표면의 전기적 저항률이 높아지고, 전하축적이 용이해지는 표면구조로 변하는 것을 확인하였다. 또한, 재료 내에서 발수성 회복역할을 하는 저분자량 성분이 감소하였고, 열적특성이 변화되는 것을 확인하였다. 이를 통하여, 최근 확산되고 있는 옥외용 고분자 절연물의 성능평가 및 수명예측에 도움이 되고자 하였다.

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Microsturcture Control and Compression Characteristics at Room and High Temperature for$\gamma$-TiAI Intermetallic Compounds with Addition Elements (제 3원소가 첨가된 금속간 화합물$\gamma$-TiAI의 미세조직 제어와 상온 및 고온 압축 특성)

  • Jeong, Jin-Seong;Lee, Dong-Hui
    • Korean Journal of Materials Research
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    • v.6 no.1
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    • pp.67-78
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    • 1996
  • 제 3원소가 첨가된 금속간 화합물 TiAI 금속간 화합물 분말을 PREP법(플라즈마 회전전극법)으로 제조하여, 통.방전 강압소결법에 의해 치밀한 소결체를 만들었다. 이에 대해 첨가 원소의 종류와 열처리에 따른 고온 및 상온 압축 특성의 변화를 조사하였다. 소결체의 미세조직은 ${\gamma}$/$\alpha$2 lamella로 이루어진 완전 변태구조였고, 결정립의 크기는 140-150$\mu\textrm{m}$였으며 계단형 결정립계를 나타내었다. 소결체를 ($\alpha$+${\gamma}$)구역인 130$0^{\circ}C$에서 2시간 동안 열처리한 결과, 모든 조성의 시편이 등축점 ${\gamma}$와 lamella로 이루어진 전형적인 duplexrn조로 변태하였다. 상온 압축 시험에서 시편은 파괴될 때까지 가공경화 현상이 나타났으며, Cr을 첨가한 시편이 가장 큰 파괴응력과 변형률을 나타내었다. 한편, 고온 압축 시험의 경우 온도상승 때문에 가공경화의 속도가 감소되었고, 80$0^{\circ}C$에서는 가공경화와 회복이 균형을 이루는 소위 정상 상태의 변형을 보였다.

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Probabilistic Analysis of System Failure (시스템 오류에 대한 확률적 분석)

  • Seong, Soon-Yong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.3
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    • pp.648-654
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    • 2010
  • Request operations and release operations occur repeatedly in resource allocation systems. The process requesting a resource acquires one by any priority-based mechanism, and returns the resource after some periods. In this system, resource failures lead to delay of resource allocation, or to termination of process holding the failed resource. To analyze this process effectively, this paper designs a probabilistic ACSR, a process algebra that extends ACSR with the probabilistic choice operation. The ability to express/analyze both request-release rates and failure-recovery rates is illustrated using probabilistic ACSR.

The Analysis of the Relation between Regional Industrial Diversity and Regional Business Cycle (지역의 산업다양성과 지역경기변동의 관계 분석)

  • Woo, Youngjin;Kim, Euijune
    • Journal of the Korean Regional Science Association
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    • v.33 no.3
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    • pp.3-19
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    • 2017
  • The purpose of this paper is to analyze the impacts of regional industrial diversity on regional business cycle response to national volatility. We employed mean group and pooled mean group estimators of panel vector error-correction models in order to control unobserved heterogeneity of the port cities, such as Pusan, Ulsan and Incheon. The results show that in various industrial regions, short-term fluctuations in the unemployment rate are small compared to other regions. On the contrary, long-term volatility of manufacturing production index is low in those regions.

Mutator effects of plasmid pKM101 and pSL4 to E. coli DNA repair (E. coli DNA 회복에 미치는 플라스미드 pKM101과 pSL4의 mutator 기능)

  • 전홍기;이상률;백형석
    • Korean Journal of Microbiology
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    • v.28 no.2
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    • pp.109-113
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    • 1990
  • The mutagenesis-enhancing plasmid pKM101 and its mutant pSL4 were introduced into Escherichia coli B/r strains possessing different DNA repair capacities ($phr^{-}, recA^{-}, uvrA^{-}, uvrB^{-}$) and determined the protection effect and mutagenecity for UV and MNNG. The mutability and protection effect of plasmid pKM101 and pSL4 were affected by different DNA repair capacity. The mutagenecity and resistance of two plasmids were increased against UV and MNNG, and plasmid pSL4 had a higher effect than pKM101. We suggest that the functional differences between pKM101 and pSL4 is due to the variety of mutator gene.

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Functional Expression of the Neurospora crassa coq-4 Gene in Saccharomyces cerevisiae. (Saccharomyces cerevisiae에서 Neurospora crassa coq-4 유전자의 기능적 발현)

  • 김은정;최상기;천재우;오계헌;이병욱
    • Korean Journal of Microbiology
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    • v.40 no.2
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    • pp.73-80
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    • 2004
  • Coenzyme Q is a quinone derivative that acts as a lipid electron carrier in the respiratory chain located at mito-chondrial inner membrane in eucaryotes or plasma membrane in procaryotes and also functions as antioxidant. A putative Neurospora crassa coq-4 gene was cloned and functionally expressed in Saccharomyces cerevisiae coq4 mutant. Complemented S. cerevisaie mutant strain was able to produce coenzyme $Q_{6}$ and showed a normal growth rate. They also showed less sensitivities to polyunsaturated fatty acids such as linoleic acid or linolenic acid. The predicted sequence of N. crassa COQ4 is consisted of 347 amino acids with a molecular mass of 39.7 kDa and showed 35% identity and 52% similarity with that of S. cerevisiae.

Experimental Study on the TWSME Characteristics using Compressive Loading Cycles (압축 하중사이클을 이용한 양방향 형상기억효과 특성 연구)

  • Yoo, Young-Ik;Kim, Hyun-Chul;Lee, Jung-Ju;Lee, Woo-Yong
    • Transactions of the Korean Society of Automotive Engineers
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    • v.17 no.4
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    • pp.101-107
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    • 2009
  • Actuators using shape memory alloys use the one-way shape recovery stress. But when external load is applied the accumulated plastic strain induced by repeated deformation is the factor of generation of uncorrect recovery stress and unreliability. To solve this problem, two-way shape memory effect (TWSME) is considered. TWSME induced by plastic deformation have advantages including simple heating cycle without external force and enough recovery force for using actuators. but there is no research on cylinder-type or tube-type shape memory alloy actuators using two-way shape memory effect until now. Therefore in this study, characteristics of two-way shape memory effect is verified through the compression experiments using cylinder-type and tube-type specimens.