• 대한정형외과 초음파학회지
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• 제8권1호
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• pp.21-25
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• 2015

이두건 장두의 병변은 단순 방사선 검사에서 확인하기는 쉽지 않으며 외래에서의 초음파 검사가 도움이 된다. 우 견관절 통증을 주소로 내원하여 초음파 검사를 통하여 이두구 주변의 종괴를 진단하였으며 이에 대하여 관절경적 절제술을 시행한 증례를 보고하고자 한다. 병리 조직 소견상, 종괴 내막은 활액막 세포의 배열은 관찰되지 않았으며 내막은 두꺼워져 있어서 결절종으로 진단되었다.

• 대한관절경학회지
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• 제8권1호
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• pp.54-57
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• 2004

슬관절에 생긴 연골종은 드물게 보고되고 있어 저자들은 본원에서 경험한 1예의 임상양상과 조직학적 소견에 대해 보고하고자 하였다. 본 증례는 특별한 외상없이 발생한 슬관절 동통 및 종창을 주소로 내원한 38세 환자에 대한 것으로 슬관절의 전방 압통이 관찰되었으며 슬관절 전반에 경한 종창이 관찰되었다. 관절경하에서 종양을 절제한 결과 2 5 ${\times}$ 1.5 ${\times}$ 1 cm크기의 비교적 단단한 종괴였으며, 이는 중심부에 갈색을 갖는 부분적인 병변이 관찰되었고, 현미경학적으로 바깥쪽에 활액막이 얇게 덮여있는 초자 연골로 구성된 연골종으로 확인되었다.

• 한방재활의학과학회지
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• 제24권2호
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• pp.31-40
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• 2014

Objectives Trachelospermi caulis, known as Nak-Suk-Deung in Korea, is the dried leafy stem of Trachelospermum asiaticum var. intermedium Nakai, and climbing stems and branches of Trachelospermum sdisyivum var, intermedium nakai or Apocyanaceae. Trachelospermi caulis has antipyretic and analgesic activity. It has traditionally been used as a folk remedy in Korea for the treatment of various infla mMatory diseases, including rheumatoid arthritis. The purpose of this study was to evaluate the Effects of Trachelospermum caulis extract on SNP-induced infla mMatory responses in rabbit HIG-82 synovial membrane cells. Methods Anti-infla mMatory effects of the extract of Trachelospermum caulis were investigated using rabbit HIG-82 synovial membrane cells. For this study, 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, western blot analysis, PGE2 i mMunoassay, and NO detection were conducted. Results The aqueous extract of Trachelospermum caulis exerted cytotoxicity and suppressed PGE2 synthesis and NO production in rabbit HIG-82 synovial membrane cells. The aqueous extract of Trachelospermum caulis also inhibited the SNP-induced expressions of COX-2, iNOS, and TNF-$\alpha$ in rabbit HIG-82 synovial membrane cells. Conclusions These results showed that the extract of Trachelospermum caulis exerts the anti-infla mMatory effect by suppressing COX-2, iNOS, and TNF-$\alpha$ expressions in the synovial membrane cells.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제37권6호
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• pp.545-549
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• 2011

Synovial sarcoma (SS) is a malignant soft tissue tumor comprising 5-10% of all soft tissue sarcomas. This tumor normally occurs in the paraarticular regions of the extremities but is rare in head and neck sites. SS is sometimes difficult to diagnose because it can mimic benign lesions both clinically and radiologically. This paper presents a rare case of a SS of the buccal space of a 25-year old man. The histology examination and immunohistochemistry of the mass led to a diagnosis of synovial sarcoma. The patient was treated primarily with a surgical resection, followed by radiotherapy and chemotherapy. The follow up examination 17-months after surgery showed no signs of tumor relapse or metastasis.

• 대한관절경학회지
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• 제15권2호
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• pp.125-131
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• 2011

후방십자인대 파열의 최선의 치료법은 논쟁의 대상이며, 후방십자인대 재건술시 고려해야할 사항들로는 경골 고정방법(transtibial vs inlay), 대퇴터널의 위치(central, eccentric or isometric), 재건다발의 수(single-bundle vs double-bundle)등이 있다. 후방십자인대는 중슬부 동맥의 분지와 가깝게 위치하고, 두꺼운 활액막에 싸여있어 손상시 전방십자인대보다 자연 치유력이 뛰어난 것으로 알려져 있다. 일반적으로 후방십자인대 재건술시, 이식물 통과를 용이하게 하고 터널 위치 선정을 위한 인대 부착부를 잘 보기 위해 남아 있는 후방십자인대 잔여 조직을 모두 제거한다. 그러나 잔여 조직을 보존하면 슬관절 후방 안정성에 기여하며, 이식물 치유를 빠르게 하고, 잔여 인대에 남아 있는 기계 수용체의 고유 수용 감각 기능을 살리게 된다. 수술 술기의 어려움과 터널 합병증이 발생될 수 있는 이중 다발 재건술에 비해, 대퇴부 인대 부착부를 보전하기 쉽고 합병증이 적은 단일 다발 재건술을 이용한 잔여 조직을 보존한 보강법이 유용한 수술 방법으로 사료된다.

• 대한관절경학회지
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• 제1권1호
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• pp.91-97
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• 1997

There has been a controversy about the effectiveness of the synovectomy of the knee in the rheumatoid arthritis. So we studied to determine if the arthroscopic synovectomy of the knee was of benefit in the rheumatoid arthritis. We ana lysed 25 knees of 15 patients who underwent the arthroscopic synovectomy of the knee joint for their rheumatoid arthritis from Jun. 1995 to Oct. 1996. The average follow-up period was 20.1 months($12\~28$ months). The results were as follows; 1. Satisfactory results were obtained in 20 knees $(80\%)$ for the pain and the effusion each, 23 $(92\%)$ for the range of motion and 19 $(76\%)$ for the functional capacity. 2. In the overall results for the pain. effusion. range of motion and the functional capacity. we obtained excellent results in 14 knees $(56\%)$ and satisfactory results in 9 knees $(32\%)$. 3. In the patient's self assessment, 11 patients $(44\%)$ were delighted and 10 patients $(40\%)$ were satisfactory. 4. In the overall results according to the articular cartilage damage, satisfactory results were obtained in 15 $(93\%)$ out of 16 knees in Grade I and II, and 6 $(75\%)$ out of 8 knees in Grade III and IV. In conclusion, arthroscopic synovectomy could be one of very useful treatments for the rheumatoid knee. But further study is needed to get the long-term results of the synovectomy because there's many reports saying gradual decrease of good results with increasing time. And continuous and proper medical treatment including DMARDs, is needed to effectively control the rheumatoid arthritis even after the synovectomy.

• 대한관절경학회지
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• 제1권1호
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• pp.112-115
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• 1997

저자들이 전방십자인대 파열과 함께 전방 불안정성을 보인 2례를 보존적으로 치료하여 좋은 임상적 결과를 얻은 바를 고려할 때, 급성기에 전방십자인대가 파열된 경우에도 전방십자인대를 싸고 있는 활액막이 파열되어 없어지지 않고 비교적 연속성이 잘 유지된 경우에는 보존적으로 치료함으로써 좋은 결과를 기대할 수 있을 것으로 사료되며 아울러 십자인대가 손상받았을 때 스스로 복원 능력이 있는 지에 대하여 새로운 연구가 필요하리라 사료된다.

• Journal of Acupuncture Research
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• 제19권2호
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• pp.177-188
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• 2002

Objective : The purpose of this study is to investigate the immunohistological effect of Buthus martensi Karsch Herbal-acupuncture in treating the arthritis, performed several experimental items : those are paw edema, $IL-1{\beta}$, IL-6, IL-8, $TNF-{\alpha}$ and $PGE_2$. Methods : All the male Sprague Dawley rats used in this study were bred and maintaned in our pathogen-free rat colony and were 8 weeks of age at the start of to experiment. The experimental model of arthritis was induced by injection of $50{\mu}g/{\mu}{\ell}$ adjuvant(mineral oil mixed Mycobacterium butyricum). Buthus martensi Karsch Herbal-acupuncture was injected into ST36(足三里) of rats daily for 21 days. Immunohistological analysis was carried out to assess paw edema, $IL-1{\beta}$, IL-6, IL-8, $TNF-{\alpha}$ and $PGE_2$ expression in synovial membrane and sera Buthus martensi Karsch Herbal-acupuncture injected. Results : Buthus martensi Karsch Herbal-acupuncture group showed a decrease with statistical significance, in paw edema, $IL-1{\beta}$, IL-6, IL-8, $TNF-{\alpha}$ and $PGE_2$ in synovial membrane and sera compared with control group. Conclusion : Buthus martensi Karsch Herbal-acupuncture stimulation inhibited the development of immunity to adjuvant induced arthritis in rats. Thus, Buthus martensi Karsch Herbal-acupuncture may have preventive effects on autoimmune inflammatory joint diseases as arthritis. The effect of Buthus martensi Karsch Herbal-acupuncture on the immune function and the disease activity in patients with arthritis warrants further investigation.

• 대한족부족관절학회지
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• 제13권1호
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• pp.14-18
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• 2009

Purpose: We evaluated the results of treatment and clinical symptoms of 11 cases of synovial chondromatosis in the ankle joint. Material and Method: From February 2001 to May 2008, 11 cases with synovial chondromatosis involving ankle joint underwent surgical treatment. There were 5 males and 6 females. The average age at surgery was 51 years. The average follow-up period was 42 months. Duration from onset of symptom to treatment was 117 months. Chief complaints of patients, 9 cases were pain and 1 case was mass like lesion, 1 case was found on x-ray. Preoperatively, all cases were evaluated on simple x-ray, 4 cases on CT, 4 cases on MRI and 1 case on ultrasonogram. 10 cases underwent synovectomy and loose body removal. 5 cases of 10 cases underwent open synovectomy and loose body removal and arthrosocpic surgery. 4 cases of 10 cases underwent only open synovectomy and loose body removal and 1 case of 10 cases underwent only arthroscopic surgery. 1 case underwent tibiotalar arthrodesis. Results: The location of loose bodies was 7 cases on posterior and 4 cases on anterior and 4 case on lateral and 3 cases on multiple site. Postoperatively, all patients showed marked clinical improvement and had subjective satisfaction except reoperation 2 cases and arthrodesis 1 case. AOFAS score of all patients was average 82.2. Conclusion: Clinical results of the synovial chondromatosis of ankle joint were satisfactory. More accurate preoperative evaluation is required to achieve prevention of postoperative recurrence and better outcome.

• Journal of Acupuncture Research
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• 제22권4호
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• pp.55-63
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• 2005

목적 : 만성 염증성 질환에 대한 전침효과를 알아보기 위해 complete Freund's adjuvant (CA) 유발 관절염 모델에서 염증관련 단백질의 변화를 살펴보았다. 방법 : Sprague-Dawley계 흰쥐의 족부에 CFA를 주사한 다음 3일 간격으로 2 Hz, 15 Hz 및 120 Hz 전침 자극을 주며 부종 형성여부를 plethysmometer로 측정하여 판정하였으며 30일 째 거퇴관절을 취하여 4% paraformaldehyde에 고정하고 EDTA용액에서 탈회시켜 파라핀연속 절편을 얻어 $NF-{\kappa}B$를 비롯한 5종의 염증관련 단백질의 발현을 면역조직화학적으로 살펴보았다. 결과 : 관절연골내 면역반응 중 연골기질은 반응이 없거나 약하고 연골세포는 $NF-{\kappa}Bp65,\;I-{\kappa}B{\alpha},\;iNOS$반응이 강하며 특히 유리연골층에서 더 현저하였으나 염증 및 전침자극에 따른 변화는 없었다. 관절낭에서 면역반응을 살펴보면 염증유발시 활액세포의 면역반응세포는 $I-{\kappa}B{\alpha}$가 감소한 반면 iNOS, $IL-1{\beta}$는 증가하며 특히 iNOS 증가가 현저하였으며 전침자극에 의해 iNOS가 감소하였다. 활액막조직에서 모든 면역반응이 증가하며 특히 $NF-{\kappa}Bp65,\;I-{\kappa}B{\alpha},\;iNOS$ 반응이 현저한데 전침자극에 의해 $IL-1{\beta}$를 제외한 모든 반응이 감소하였다. 결론 : 만성 염증성 동물모델의 거퇴관절 내 염증관련 단백질은 관절연골보다 관절낭에서 큰 변화를 보이며 전침처치에 의해 이들 단백질 발현이 억제되는 것으로 보아 전침이 만성 염증성 질환에 효과적임을 알 수 있다.