• Journal of Life Science
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• v.27 no.3
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• pp.289-294
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• 2017

Diabetes mellitus is associated with insulin resistance, which leads to down-regulation of insulin signaling and the decreased glucose uptake. Adipocytes are sensitive to insulin, and closely implicated in insulin resistance and diabetes. Insulin stimulates differentiation of preadipocytes to adipocytes, and increases glucose transport. Allium species have been used as traditional medicine and health-promoting foods. Allium hookeri (A. hookeri) is reported to improve the pancreatic ${\beta}-cell$ damage and exhibit pancreatic anti-inflammatory activity in streptozotocin-induced diabetic rats. We investigated whether A. hookeri extract (AHE) may stimulate glucose uptake in adipocytes through increasing insulin sensitivity. AHE enhanced fat accumulation, a differentiation biomarker, under the partial induction of differentiation by insulin. $PPAR{\gamma}$, a transcription factor highly expressed in adipocytes, promotes adipocyte differentiation and insulin sensitivity. AHE increased the differentiation of preadipocytes through up-regulation of $PPAR{\gamma}$. The activation of $PPAR{\gamma}$ increases the GLUT4 expression during adipocyte differentiation. GLUT4 is responsible for glucose uptake into the adipocytes. AHE increased the expression of GLUT4 in adipocytes, and subsequently enhanced the insulin-stimulated glucose uptake. These results suggest that AHE promotes adipocyte differentiation through activation of $PPAR{\gamma}$, and leads to enhance glucose uptake in adipocytes along with GLUT4 up-regulation. Thus, AHE may be effective for the insulin-sensitizing and anti-diabetic activities.

• Journal of the Korean Chemical Society
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• v.35 no.2
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• pp.99-104
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• 1991

Nonstoichiometric solid solutions of Sr$_{1+x}Er _{1-x} FeO _{4-y}$ system (x = 0.00, 0.25, 0.50, 0.75 and 1.00) with layered $K_2NiF_4$ type structure were prepared at 1350$^{\circ}$C under atmospheric pressure. By the analysis of X-ray diffraction, the crystallographic structures of the solid solution of all compositions were found to be pseudo-tetragonal system. Nonstoichiometric chemical formulas have been determined by Mohr salt analysis. It shows that the amount of Fe$^{4+}$ increases with increasing x up to 0.50 and then decreases, and the value of oxygen nonstoichiometry increases with increasing x value. Mixed valency states of Fe$^{3+}$ and Fe$^{4+}$ in the sample were identified again by Mossbauer spectroscopic analysis at 298 K. Electrical conductivity varied within the semiconductivity range of 10-2 ∼ 10-7(${\Omega}$-1cm-1), activation energy for electrical conduction decreased with the increment of the mole ratio of Fe$^{4+}$ or ${\tau}$ value. The conduction mechanism could be explained by the hopping model of the conduction electrons between the valency states of Fe$^{3+}$ and Fe$^{4+}$.

• Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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• 2003.04a
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• pp.62-62
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• 2003

Landsat TM 영상을 이용, 명암차가 높은 산악 지역에 적용해왔던 알고리즘을 개선하여 비교적 명암차가 낮고 넓게 분포하는 충적층 지역의 선구조를 추출하는 알고리즘을 개발하였다. 수치지형모델(OEM)에 대하여 Local Enhancement 를 이용해서 평탄한 지역을 선정하여 이로부터 충적층을 추출하였다. Zevenbergen & Thorno's Method를 3×3 moving windowing을 통해서 최대 경사방향과 경사를 구해서 충적층을 지나는 선구조 요소를 추출하고 다시 Hough 변환을 이용해서 1차 선구조를 추출하였다 이를 이용하여 충적층의 직각방향의 지형단면의 경사를 유추해서 spline 보간법을 이용해 단면의 최저점을 구하고 이 구해진 점들을 다시 Hough 변환을 이용해서 최종 선구조를 추출하였다. 본 연구에서 사용한 알고리즘은 기존 알고리즘에서 사용된 소창문보다 훨씬 큰 충적층이 분포하는 지역의 지형 경사가 수렴하는 부분에 선구조가 뚜렷이 나타남을 볼 수 있다. 최대경사방향과 경사를 구해서 얻어진 1 차선구조와 최종 선구조에서 선구조 방향이 다소 차이를 보인다. 1 차 선구조의 수직방향 지형단면의 자료를 이용함에 있어, 지형 단면의 시작정과 끝지점을 임의적으로 결정하는 것이 아니라, 충적층을 가로질러 최고점까지 또는 다음 충적층이 나을 때까지의 자료를 이용해서 보간법을 사용하였고, 충적층의 넓이에 따라 보간할 자료량의 차이에 의한 오차가 발생할 수 있다. 넓은 충적층에서 선구조가 잘 추출되는 반면에 좁은 충적층이 분포하거나 계곡에 해당하는 지역에l서는 경사수렴부와 일치하지 않는 선구조가 추출되었다. 이는 향후 계속적으로 연구해서 보완되어야 할 것으로 사료된다.페클 잡영 제거 정도에 있어 다른 필터들과 큰 차이가 없지만 경계선보존지수는 다른 필터들에 비하여 가장 우수함을 확인할 수 있었다.rbon 탐식효율을 조사한 결과 B, D 및 E 분획에서 유의적인 효과를 나타내었다. 이상의 결과를 종합해볼 때, ${\beta}$-glucan은 고용량일 때 직접적으로 또는 $IFN-{\gamma}$ 존재시에는 저용량에서도 복강 큰 포식세로를 활성화시킬 뿐 아니라, 탐식효율도 높임으로써 면역기능을 증진 시키는 것으로 나타났고, 그 효과는 crude ${\beta}$-glucan의 추출조건에 따라 달라지는 것을 알 수 있었다.eveloped. Design concepts and control methods of a new crane will be introduced in this paper.and momentum balance was applied to the fluid field of bundle. while the movement of′ individual material was taken into account. The constitutive model relating the surface force and the deformation of bundle was introduced by considering a representative prodedure that stands for the bundle movement. Then a fundamental equations system could be simplified considering a steady state of the process. On the basi

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.46 no.4
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• pp.7-16
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• 2009

A robot must be able to generate various skills to achieve given tasks intelligently and reasonably. The robot must first learn affordances to generate the skills. An affordance is defined as qualities of objects or environments that induce actions. Affordances can be usefully used to generate skills. Most tasks require sequential and goal-oriented behaviors. However, it is usually difficult to accomplish such tasks with affordances alone. To accomplish such tasks, a skill is constructed with an affordance and a soft behavioral motivation switch for reflecting goal-oriented elements. A skill calculates a behavioral motivation as a combination of both presently perceived information and goal-oriented elements. Here, a behavioral motivation is the internal condition that activates a goal-oriented behavior. In addition, a robot must be able to execute sequential behaviors. We construct skill networks by using generated skills that make action selection feasible to accomplish a task. A robot can select sequential and a goal-oriented behaviors using the skill network. For this, we will first propose a method for modeling and learning Bayesian networks that are used to generate affordances. To select sequential and goal-oriented behaviors, we construct skills using affordances and soft behavioral motivation switches. We also propose a method to generate the skill networks using the skills to execute given tasks. Finally, we will propose action-selection-mechanism to select sequential and goal-oriented behaviors using the skill network. To demonstrate the validity of our proposed methods, "Searching-for-a-target-object", "Approaching-a-target-object", "Sniffing-a-target-object", and "Kicking-a-target-object" affordances have been learned with GENIBO (pet robot) based on the human teaching method. Some experiments have also been performed with GENIBO using the skills and the skill networks.

• Journal of the Korean Chemical Society
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• v.37 no.11
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• pp.923-928
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• 1993

The series of solid solutions in the $Sr_{1+x}Ho_{1-x}FeO_{4-y}$ (x = 0.00, 0.25, 0.50, 0.75 and 1.00) systems with $K_2NiF_4$ type structure have been prepared at 1550$^{\circ}$C under an atmospheric air pressure. The X-ray powder diffraction spectra of these samples assign that the crystallographic phases are tetragonal system over the whole x range. The lattice volume was increased with increasing the substitution amount of the $Sr^{2+}$ ion. The mole ratio of the $Fe^{4+}$ ion to total iron ions or ${\tau}$ value has been determined by Mohr salt titration of the sample and then the y value was calculated from x and ${\tau}$ values. The ${\tau}$ and y values have been increased with x values. The nonstoichiometric chemical formula are formulated from the general formula of $Sr_{1+x}Ho_{1-x}Fe^3_{1-}\;^+_{\tau}Fe_{\tau}^{4+}O_{4-y}$ replaced by x,${\tau}$ and y values. Mossbauer spectra show the mixed valence state and coordination state of $Fe^{3+}\;and\;Fe^{4+}$ ions. It is found out that the magnetic property of the samples is paramagnetic at room temperature. Electrical conductivity varied within the semiconductivity range of 1.0 to 1 ${\times}\;10^{-9}{\Omega}^{-1}cm^{-1}$. Activation energy of the electrical conductivity was decreased with the $\tau$ value. The conduction mechanism should be explained by the hopping model of the conduction electrons between the valence states of $Fe^{3+}\;and\;Fe^{4+}$ ions.

• Management & Information Systems Review
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• v.34 no.2
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• pp.171-191
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• 2015

This study is about the exhibition and convention visitors' satisfaction level and the participating companies' perception on the performance. The two topics were approached with integrated model. Accordingly, this study examined how service quality and experiential quality affect exhibition and convention visitors' satisfaction level and the participating companies' perception on the performance, and how the correlation between exhibition and convention visitors' satisfaction level and the participating companies' perception on the performance is affected. The result demonstrates that the quality of experience exerts positive effect on the visitors' sense of satisfaction(Hypothesis 3), while service quality is not statistically significant when it comes to the visitors' satisfaction(Hypothesis 1). When the correlation between service quality and experiential quality, and the participating companies' perception on the performance is examined, service quality exerts positive effect on the participating companies' perception on the performance(Hypothesis 2), while experiential quality is not statistically significant on the participating companies' perception on the performance(Hypothesis 4), When the correlation between exhibition and convention visitors' satisfaction level and the participating companies' perception on the performance is examined, it was shown that positive effect is exerted just like the results of the previous studies(Hypothesis 5), lastly, correlation between participating companies' perception on the performance, companies' satisfaction and company loyalty was examined. In case of the participating companies' perception on the performance, it exerts positive effect on the companies' satisfaction(Hypothesis 6), while company loyalty is not statistically significant (Hypothesis 7). In case of companies' satisfaction, it exerts positive effect on the company loyalty (Hypothesis 8). The results of this study will provide help to increase overall understanding of the exhibition and convention visitors' satisfaction level and the participating companies' perception on the performance, and to provide important implications for the development of strategy for exhibition and convention's vitalization.

• Korean Security Journal
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• no.46
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• pp.7-30
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• 2016

This study found the strategies for activating the security industry to utilize social network services based on the platform business model. This research was utilized for in-depth interview and IPA analysis. And use it was to check the contents and strategic improvement projects that can actually materialize and direction of the strategy. First, run a priority need area is a private center of community policing related portal development and operation, universal social networking service(SNS) utilizing expanded, professional training, IT-based security content management and operation of IT infrastructure security guards and security professionals up educational content development, online security guards and security professionals-up refresher training program development. Second, the area over the inventory capabilities increase the effectiveness of the security guards was constructed open-type comprehensive public information system. Third, the area needed to be reviewed are the individual security industry experts workers operating information channels, dedicated customer service and expanding the event of a private security guard & security service providers up. Fourth, the effectiveness of the insufficient area are discuss system improvements, the sharing of community policing closed Cameras for proposals for the expanded utilization of social networking services, private development organizations Social Network Service(SNS).

• Korean Journal of Social Welfare
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• v.37
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• pp.217-239
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• 1999

The main premise of this study is that a successful treatment and rehabilitation of the mentally ill depends on an active. coping of their family members, who are the primary care-takers of the patients, even if families are confronting many difficulties because of caring their patients. Accordingly, this study aims to find out which factors are related to families active coping with the mentally ill. This study is conducted the survey with 191 family members of the mentally ills in order to discover: 1) what kinds of relations do exist between sociodemographic factors of the respondents, care-burden toward the mentally ill, and social supports, and the active coping, and 2) in what extent do these related factors affect on the active coping. The major findings of the study are: 1) gender and educational background of the respondents are positively related to the active coping; 2) regarding care-burden felt by the respondents, there is statistically significant positive relationship between - the respondents' burden due to a lack of social and institutional support and their active coping; 3) considering the relationship with social support, there is highly positive relationship between decision. emotional. material supports and the active coping; 4) using a multiple regression, respondents' sociodemographic background, care-burden, social support affect significantly on the active coping by 26.2% of explanatory power; and 5) using a step-wise multiple regression, the most powerful influenced factors on active coping are emotional support, burden due to a lack of social and institutional support, and educational background of the respondents. In conclusion, this study recommends clinicians to use an educational and support model for the families. All these efforts will contribute to enhance active coping of the families with the mentally ill.

• Journal of the Korean Geographical Society
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• v.40 no.6 s.111
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• pp.770-788
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• 2005

In this article, major research trends are examined mainly from articles published in Journal of the Korean Geography, academic society journals of sub-fields in geography and Ph.D. dissertations in geography of universities in Korea. Based on the research trends up to current point, issues and research directions in order to raise the status of Korean Geography in the twenty first century are prospected. Sixty years of Korean Geography can be divided into 4 periods such as before 1970s, during the 1980s, during the 1990s, and the period after the 2001. Each period of time revealed distinct aspects of development both quantitatively and qualitatively. For the last 60 years, the study of Korean Geography has gone through enormous changes in the number of articles with dynamics and variety in contents and methodology, breathing with the changes of the Korean society. Experiencing urbanization and industrialization along with rapid economical growth, the study of Korean Geography has progressed by analyzing the issues and problems of national space and conducting various researches from the case studies for problem-solving to the theoretical and policy oriented studies. The key-words such as 'knowledge based information society', 'aged society', and 'the era of globalization' will be realized in the twenty flit century. And environment-friendly policies for sustainable development will be more stressed in a globalized world. In order to provide research methods and alternatives suitable for newly transformed global society and for utilizing the essence of Geography in the future, the studies on Korean Geography should actively focus on integrative studies between physical and human geography, on interdisciplinary studies, on regional studies related to foreign countries and North Korea, and on the establishment of Korean geographical theory and model.

• Biomedical Science Letters
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• v.3 no.2
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• pp.83-88
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• 1997

In septic patients, disseminated intravascula. coagulation (DIC) occurs frequently and is a pathologic condition associated with a variety of critical illness. DIC may complicate the already complex clinical situations and contribute to the high mortality. Nevertheless, its pathogenic mechanisms are not completely elucidated. Present study was prospectively designed to understand the pathogenetic mechanisms involved in the development of DIC. 15 rats were subjected to study and according to the aim, they were divided into three groups： group I, control (not treated-endotoxin, n=5)； group II (12 hours after endotoxin injection, n=5)； group III (24 hours after endotoxin injection, n=5). Experimental DIC was induced in rats by a bolus injection of endotoxin (1mg/kg, E. coli serotype 055:B5). Blood was collected by direct puncture of the heart. Platelet count, fibrinogen and plasminogen concentration, antithrombin III, D-dimer and complement components (C3 and C4) were measured in all subjects. In group II and III, there were apparent signs of DIC, including thrombocytopenia, decreased fibrinogen (but increase in group III), reduced C3 and antithrombin III, and elevated D-dimer. These data indicated that endotoxin might induce the activation of several pathways such as coagulation, fibrinolytic and complement cascade, causing DIC and subsequent multiple organ failures. Ultimately, the increased knowledge of the various pathogenetic mechanisms of coagulation activation and fibrinolysis in endotoxin-induced DIC may have prophylactic or therapeutic implications.