• Korean Journal of Head & Neck Oncology
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• v.27 no.1
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• pp.22-26
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• 2011

목 적 : 두경부 암은 발생 순위에서 전체 6위에 해당하는 다빈도 암이나 최근 20여년 동안의 노력에도 불구하고 두경부 암의 독톡한 특성상 생존률에서 뚜렷한 향상을 보이지 못하고 있다. 특히, 하인두 암은 원발 부위의 점막하 침윤이 흔하며, 주변 림프절 전이와 원격 전이가 흔하고, 2차 원발 암종 발생이 흔하여 두경부 암 중에서도 가장 불량한 예후를 보이고 있는 악성 종양이다. 최근에 이러한 암을 치료하고 진단하기 위한 방법으로 분자생물학적 접근법들이 많이 시도 되고 있으며, 그 중 하나로 N-myc downstream regulated gene-1(Ndrg-1)이라는 유전자가 유방, 전립선, 방광 암 등의 타 악성 종양에서 종양의 전이 및 진행 양상과 관련되어 있다는 보고가 있었다. 이에 본 연구는 하인두 암에서의 Ndrg-1의 발현 양상을 살펴보고 이와 임상 양상과의 연관관계를 살펴보고자 하였다. 방 법 : 1996년부터 2003년까지 수술 받은 하인두 암 환자 56명을 대상으로 면역조직화학검사를 시행하여 Ndrg-1 발현을 확인하였고, 3명의 신선 조직을 대상으로 RT-PCR, Western blot을 시행하였다. 결 과 : Ndrg-1은 RT-PCR에서 정상 조직과 악성종양 조직 모두에서 비슷한 수준으로 발현되었다. 그러나 Western blot에서는 정상 조직에서 뚜렷한 증가 양상을 보여 타 연구와 동일한 결과를 보였고, 이는 불필요하며 비효율적인 mRNA수준에서의 발현이 있지만 최종적인 단백 산물 발현에서는 암종의 진행과 연계되어 악성 종양 진행군에서 발현이 억제되는 결과로 해석된다. 면역조직화학검사에서는 정상 상피조직에서 Ndrg-1 발현이 확인되었으며, 통계적으로 유의하지는 않으나 불량한 예후를 가진 그룹에서 대체로 발현이 억제되는 악성 종양과의 역 연관 관계를 확인할 수 있었고, 특히 림프절 전이를 보인 그룹과 그렇지 않은 그룹 사이에서는 통계적으로 유의미한 결과가 확인되었다. 결 론 : 즉, 림프절 전이가 없는 그룹에서 Ndrg-1이 종양의 전이에 관여할 것이라는 타 연구와 일관된 결과로 하인두 암에서도 그 역할이 있음을 나타내는 결과라 할 수 있다.

• Health Policy and Management
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• v.26 no.3
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• pp.233-241
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• 2016

Background: This study purposed to analyze and understand how spatial accessibility of patients influenced the number of outpatient visits for the internal medicine of a hospital. Methods: A hospital with 100 beds in Seoul, South Korea provided data from 2013 January 1 to 2013 June 30. Euclidean distance and road ares were used to represent the spatial accessibility. Patient level data and dong level data were collected and used in spatial analysis. Dong level data was converted into grid level ($500{\times}500m$) for the multivariate analysis. Hot-spot analysis and generalized linear model were applied to the data collected. Results: Hot-spots of outpatient visits were found around the study hospital, and cold-spots were not found. Number of outpatient visits was varied by the distance between patient resident and hospitals, and about 80% of total outpatient visits was occurred in within the 5 km from study hospital, and 50% was occurred in within 1.6 km. Spatial accessibility had significant influences on the outpatient visits. Conclusion: Findings provide evidences that spatial accessibility had influences on the patients' behaviors in utilizing the outpatient care of internal medicine in a hospital. Results can provide useful information to health policy makers as well as hospital managers for their decision making.

• Therapeutic Science for Rehabilitation
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• v.9 no.4
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• pp.21-31
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• 2020

Objective : Reminiscence program is a method to restore psychological stability for the elderly having dementia, and at the same time it makes the aged with dementia express themselves correctly by helping them to recollect their past life memories. The purpose of this study was to investigate the effects on communication ability in applying the reminiscence program to elderly patients with Alzheimer's dementia. Methods : The subject were 4 patients whose Alzheimer's dementia of moderate. This experiment was designed with pre-stage, treatment-stage, post-stage. The reminiscence therapy was compose of reminiscence activities of their live; in their childhood, adolescence, adulthood, and senescence. The therapy was delivered 30 times for 15 weeks. Results : The result of the study were as follows. First, after reminiscence therapy, recognition ability was improved. Second, after reminiscence therapy, emotional side was improved. Third, after reminiscence therapy, communication ability was improved. Conclusion : In this study, the reminiscence therapy had a positive effect on the improvement of communication skills among the elderly with Alzheimer's dementia. Based on the reminiscence therapy, it is thought to be very helpful in improving the communication ability of the elderly with dementia in the future.

• Journal of Chest Surgery
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• v.41 no.1
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• pp.61-67
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• 2008

Background: Conventional ascending aortic cross clamping is often limited. This study was carried out to evaluate the safety and efficacy of an endovascular aortic clamping technique with an intraaortic balloon catheter. Material and Method: From April 2004 to January 2007, surgery with endoaortic clamping was performed in seven patients. A retrograde access perfusion (RAP) catheter was used in six patients and a Pruitt's balloon catheter in two patients. The indication for the operation was a retrosternal pseudoaneurysm of the aortic root in six patients, diffuse calcification of the ascending aorta with aortic regurgitation in 2 patients and an atrial septal defect in one patient. Five patients had at least two prior cardiac surgeries. Result: Successful insertion of the catheter and endoaortic clamping was achieved in all patients. Conclusion: The endovascular aortic clamping technique with a balloon catheter was a useful alternative method for patients in whom conventional cardiac surgery was limited.

• Health Policy and Management
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• v.18 no.3
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• pp.1-17
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• 2008

The measurement and management of patient satisfaction has become one of the key issues in the last two decades. Hospitals must thoroughly understand the needs of their customers and design products and health services that meet and exceed their expectations. The importance-performance analysis(IPA) is a widely used analytical technique that yields strategies for managing customer satisfaction in a variety of applications. IP A is a two-dimensional grid based on customer-perceived importance of quality attributes and attribute performance. Depending on the interplay of these two dimensions, four strategies can be derived. The aim of this study is to develop the management strategies for improving patient satisfaction in university hospitals using the I-P analysis. The attributes on inpatient service quality in 4 university hospitals was investigated using the Martilla and James(l977)' s a mean adjusted I-P grid where the axes of the grid cross at the average rating point of all items. The patient satisfaction questionnaires were completed by 600 hospital inpatients. The main statistical methods are path analysis and IPA with SPSS 12.0 and AMOS 4.0 statistical softwares. The two attributes, physician and medical service, administrative staff kindness attributes position in first quadrant(Keep Up the Good domain). The nurse and nursing service attributes position in second quadrant(Possible Overkill domain). The two attributes, convenience of check-in service, facilities and physical environment position in third quadrant(Low Priority domain). Finally the quality of inpatient service(food etc.) attributes position in fourth quadrant(Concentrate Here domain). These findings show various implications on the development of strategies in university hospitals in the future. It was determined that quality of inpatient service(food etc.) need to concentrate more on investments. These investments include a taste, price, proper provision of food service and quick response of pain management. A low priority was given to investment in streamlining the check-in process of inpatient and hospital facilities and physical environment in the long run.

• Journal of Korea Game Society
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• v.13 no.4
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• pp.73-90
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• 2013

Serious games allow learners to experience situations that are impossible in the real world for various purposes. To date the major applications of serious games include military, government, education, corporate and healthcare applications. This paper aims to provide an overview of the applications of serious games for various health-related purposes, particularly for Health and Medicine education, health risk prevention, behavioral intervention, and disease self-management. These games identified numerous papers reporting empirical evidence about the impacts and outcomes. There is potential promise for serious games to improve health outcomes. We discuss implications of using serious games for health-related purposes and future direction for research in this area.

• The Journal of the Korean dental association
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• v.54 no.10
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• pp.811-819
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• 2016

Panfacial fracture is extremely difficult to manage facial injuries but concomitant injuries and severe complications including facial esthetic and functional problems can make it harder. Thorough evaluation and closed co-work with other specialists is needed when reduction and fixation cannot be achieved quickly. Emergency bony support and soft tissue key suture provide the patients with airway integrity, hard and soft tissue vitality. A systemic treatment plan must be made by 3D CT image. This plan include airway management for surgery, sequence of reduction and fixation, approach method, soft tissue resuspension and reconstruction of lost tissue like inferior orbital wall, zygomaic buttress and soft tissue. From known to unknown structures, accurate reduction and fixation will provide proper occlusion, facial projection, width, hight and function. Consideration about facial retaining ligaments must be given to prevent soft tissue sagging.

• Journal of Digital Convergence
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• v.13 no.2
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• pp.381-391
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• 2015

The purpose of this study was to investigate the trends in research on the effects of virtual reality technology applied to rehabilitation for disabled. I have collected 60 papers published in Korea(2000-2014), and analyzed it by the P.I.C.O. method. As a result, adults and the elderly are most common subjects, and projection type has been used frequently in researches. It were included mostly balance, upper extremity function, and gait that the dependent variables represents the intervention effects. I interpreted it as the ICF factors. So, research topics were the most common mobility, in contrast to educational, vocational, recreational area as dealing with the participation area is very small. In the future, we should focused on social aspects for useful intervention in real life of people with disabilities based on virtual reality technology, and virtual reality technology should be easy to apply in terms of cost and accessibility.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.3 no.2
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• pp.65-68
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• 2010

Acromio-clavicular (AC) joint cyst have been reported in small series of the orthopedics literature in association with extensive rotator cuff tear, pseudotumor, infection of the shoulder or chondrocalcinosis. Authors experienced one case of AC joint cyst with rotator cuff re-tear after arthroscopic rotator cuff repair, clinicians may need pay attention to AC joint bulging or mass lesion after arthroscopic rotator cuff repair as an important sign to check follow-up imaging study for the cuff integrity. Especially, ultrasonography is recommended for this follow up study, because it is simple to be operated, economic, easily accessible.

• Proceedings of the Safety Management and Science Conference
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• 2002.05a
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• pp.199-205
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• 2002

최근 산업안전/보건분야에서 누적외상성질환(Cumulative Trauma Disorders： CTDs)과 직업성요통(Low Back Injury)과 같은 근골격계질환은 산업현장에서 어렵지 않게 발견할 수 있는 신종 산업재해의 일종이다. 특히 미국의 경우, 발생건수와 그로 인한 인적/물적 손실이 급격하게 증가되고 있는 것으로 나타나고 있다. 그러나 미국과 같이 근골격계질환의 폐해를 일찌감치 인식하고 그 해결방안을 연구해온 나라들에서는 현재 환자관리 및 인간공학적인 기준 등을 포함하는 예방지침들이 잘 정착되어 있는 실정이다. 우리나라의 경우에는 작업환경 등의 조건과 상황이 미국과 같은 구미 선전국과 비숫하고, 특히 제조업의 생산체계가 그런 나라들과 매우 유사하여 근골격계질환의 발생과 그로 인한 인적/물적 손실이 적지 않을 것이라고 예상할 수 있지만 아직까지 CTDs에 대한 전반적인 이해가 부족하고, 정확한 실태가 파악되지 못하였으며, 따라서 체계적인 관리 대책 또한 마련되어있지 않은 실정이다. 본 조사에서는 서울 근교의 수송기계관련 사업장의 작업들에 대한 작업자세에 중심을 둔 인간공학평가를 통하여 조사 작업의 근골격계질환에 대한 상대적인 위험도, 위험요인 등을 파악하고, 그에 따른 개선 대책의 방향을 제시하고자 하였다. 특히, 각 부위별 위험점수와 부위별 증상호소율의 상환분석결과, 작업자 개인적 수준에서는 통계적으로 유의한 차는 없는 것으로 분석되었으나, 부서별로 분석한 결과, 작업시 주로 사용하는 오른쪽 상지의 경우, 오른쪽 어깨, 팔꿈치, 손목 순으로 통계적으로 유의하게 관련이 있는 것으로 나타났다. 즉 증상호소율과 해당 신체부위의 위험도 점수는 서로 정적(positive)한 관계에 있는 것으로 나타났고, 상지 중 주로 사용하는 오른쪽 부담의 위험도 자세 점수와 증상호소는 비교적 높은 상관관계에 있는 것으로 나타났다. 따라서 이와 같은 인간공학적 분석결과는 향후 인간공학적인 개선대책의 개발 뿐만 아니라 의학쪽에서 근골격계질환을 접근하는 초기단계에서 매우 유용한 역할을 할 수 있으리라 생각된다.