• Nuclear Medicine and Molecular Imaging
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• v.42 no.1
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• pp.17-28
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• 2008

Purpose: It was well known that cerebral blood perfusion is normal or diffusely decreased in the majority of patients with Parkinson's disease (PD). Actually we interpreted brain perfusion SPECT images of PD patients in the clinical situation, we observed various cerebral perfusion patterns in patients with PD. So we performed brain perfusion SPECT to know the brain perfusion patterns of PD patients and the difference of perfusion patterns according to the sex and the age. Also we classified PD patients into small groups based on the brain perfusion pattern. Methods and Materials: Two hundred nineteen patients (M: 70, F: 149, mean age: $62.9{\pm}6.9$ y/o) who were diagnosed as PD without dementia clinically and 55 patients (M:15, F:40, mean age: $61.4{\pm}9.2$ y/o) as normal controls who had no past illness history were performed $^{99m}Tc$-HMP AO brain perfusion SPECT and neuropsychological test. Results: At first, we compared all patients with PD and normal controls. Brain perfusion in left inferior frontal gyrus, left insula, left transverse temporal gyrus, left inferior parietal lobule, left superior parietal lobule, right precuneus, right caudate tail were lower in patients with PD than normal controls. Secondly, we compared male and female patients with PD and normal controls, respectively. Brain perfusion SPECT showed more decreased cerebral perfusion in left hemisphere than right side in both male and female patients compared to normal controls. And there was larger hypoperfusion area in female patients compared with male. Thirdly, we classified patients with PD and normal controls into 4 groups according to the age and compared brain perfusion respectively. In patient below fifties, brain perfusion in both occipitoparietal and left temporal lobe were lower in PD group. As the patients with PD grew older, hypoperfusion area were shown in both frontal, temporal and limbic lobes. Fourthly, We were able to divide patients into small groups based on cerebral perfusion pattern. There was normal cerebral blood perfusion in 32 (14.7%) of 219 patients with PD, decreased perfusion on the frontal lobe in 45 patients (20.6%), the temporal lobe in 39 patients (17.4%), the parietal lobe in 39 patients (17.9%), the occipital lobe in 40 patients (18.3%), diffuse area in 14 patients (6.4%) and unclassified in 10 patients (4.6%). Fifthly, we compared the results of the neuropsychological test and cerebral perfusion pattern. There was no correlation between two tests except visuospatial function. Conclusion: Various perfusion state were found in patients with PD according to the age and sex. Also we were able to classify perfusion state into several groups and compare the neuropsychological test with cerebral perfusion.

• Journal of Digital Convergence
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• v.16 no.11
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• pp.363-372
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• 2018

The objective of this study is to derive specific classification rules that could be used to prevent individuals with Metabolic Syndrome (MS) from developing diabetes. Specifically, we aim to identify rules which classify individuals with MS into those without diabetes (class 0) and those with diabetes (class 1). In this study we collected data from Korean National Health and Nutrition Examination Survey and built a decision tree after data pre-processing. The decision tree brings about five useful rules and their average classification accuracy is quite high (75.8%). In addition, the decision tree showed that high blood pressure and waist circumference are the most influential factors on the classification of the two groups. Our research results will serve as good guidelines for clinicians to provide better treatment for patients with MS, such that they do not develop diabetes.

• Radiation Oncology Journal
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• v.18 no.4
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• pp.221-225
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• 2000

Purpose : This study was designed to examine the reliability of the new version of the AJCC staging system (1997) of nasopharyngeal carcinoma in comparison with the AJCC staging system of 1992. Materials and Methods :Between 1983 and 1996, 185 patients with histologically proven nasopnaryngeal carcinoma were treated with radiation therapy at the Department of Therapeutic Radiology Seoul National University Hospital. For these patients, AJCC staging system of 1992 was compared with the 1997 version by reviewing hospital records, computed tomography (CT) and/or magnetic resonance imaging (MRI). Results :5-year overall suwival rates according to the 1992 and 1997 AJCC staging systems were 100$\%$, and 100$\%$ at stage 1: 100$\%$, and 68.8$\%$ at stage 11; 61.4$\%$, and 63.8$\%$ at stage 111; 61.1$\%$, and 63.2$\%$ at stage IV. S-year overall survival rates of each classification showed significant differences between stages (p=0.0049 for the old version, p=0.01 for the new), but no significant difference was found between the staging systems except at stage 11. Conclusion : The new AJCC staging system allows staging as reliably as the 1992 version, but the adequacy of the newly modified staging classification should be confirmed by further clinical examination.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.626-634
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• 2018

This retrospective study investigates the accuracy of triage procedures for pediatric patients in emergency departments (EDs) using the Korean Triage and Acuity Scale (KTAS). The study includes 250 randomly selected initial nursing records and clinical outcomes of pediatric patients who visited one regional ED or a local ED from October 2016 to September 2017. The collected data were analyzed by a qualified expert to determine the true triage score. The accuracy of triage was defined as the agreement between the triage score of the emergency nurses (ENs) and the true triage score as determined by the expert. Based on expert comments, the cause of the triage error was analyzed and the KTAS score was compared with the discharge, length of stay (LOS), and medical cost. The results showed that the degree of agreement in the triage score between the experts and the ENs was excellent (weighted kappa=0.77). Among the causes of triage discordance, the most frequent was the incorrect application of vital signs to the KTAS algorithm criteria (n=13). Patients with high severity KTAS levels 1 and 2 were discharged less often (${\chi}=43.25$, p<0.001). There were significant differences in the length of stay (F=12.39, p<0.001) and cost (F=11.78, p<0.001) between KTAS scores when adjusting for age. The results of this study indicate that KTAS is highly accurate in EDs. Hence, the newly developed triage tool is becoming well established in Korea.

• Journal of Chest Surgery
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• v.34 no.2
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• pp.162-166
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• 2001

배경: 흉선암은 드문 질환으로 치료경과 및 예후가 침윤성 흉선종에 비해 나쁜 것으로 알려져 있으며 병기의 분류나 병기에 따른 치료방법이 아직 표준화 되어있지 않아 치료에 어려운 점이 있다. 이에 본교실에서 흉선암으로 진단되었던 환자들의 피료방법 및 성적을 분석하여 그 결과를 보고하고자 한다. 대상 및 방법: 계명대학교 동산의료원 흉부외과학교실에서는 1984년 8월에서 흉선암으로 진단되었던 8례의 환자를 대상으로 의무기록을 참고하여 병기에 따른 치방법료 및 예후 등을 후향적으로 분석하였다. 결과: 연령은 23세에서 67세까지로 평균 46세였으며 전흉부통증이 주증상이었다. 조직학적으로는 임파상피양암(lymphoepithelioma-like carcinoma)이 2례, 편평상피암(squamous cell carcinoma)이 2례, 기저세포암(basaloid carcinoma)이 1례, 혼합형(mixed type)이 3례 있었다. 임상적 병기분류는 Masoka의 분류법을 사용하였으며 제I기 2례, 제II기 4례, 제III기 1례, 제IVAr기가 1례 있었다. 4례의 환자에서는 종양의 완전적출이 가능했으며 3례에서는 고식적 수술을 시행하였다. 1례의 환자는 주위조직으로의 침윤과 심낭에 퍼져있어 조직생검만을 시행하였다. 전례에서 보조적 항암치료를 받았고 술후 병기가 제III기 이상이거나 종양의 절제가 불완전했던 5례의 환자에서는 보조적 방사선치료를 병행하였다. 이들 중 5례에서 술후 보조적 항암치료 및 방사선치료를 받고 현재까지 생존해있다. 평균추적기간은 55.3$\pm$64.6 개원이었고, 3례의 환자는 사망하였으며 4례의 환자는 종양의 재발증거 없이 생존해있다. 결론: 종양의 조기진단과 완전종양적출후 적극적인 보조적 항암치료 및 방사선치료가 흉선암을 치료하는데 도움이 될 것으로 사료된다.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1985-1986
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• 2008

혀의 상태는 인체 내부의 생리적 병리적 특성의 변화를 나타내므로, 한의학에서 중요한 지수가 된다. 한의학에서 설진 방법은 환자의 설질과 설태의 변화를 관찰함으로써 질병을 진찰하는 방법이므로, 편리할 뿐만 아니라 비침습적이고, 널리 쓰이고 있다. 그러나 설진은 광원, 환자의 자세, 한의사의 상태와 같은 검사 환경에 의해 영향을 받는다. 표준화된 진단을 위한 자동 진단 시스템을 개발하기 위하여 질병의 예후를 판단할 수 있는 설태 분류 방법은 필수적이지만, 컬러의 경계가 모호하므로 설태와 설질을 구분하기는 매우 어렵다. 이 논문에서 분할된 설체 내에서 컬러를 계층적으로 분류하여 설태를 분류하는 방법을 제안한다. 또한 설태 영역을 정확하게 분할하도록 하였다. 제안된 방법은 표준화된 진단을 가능하도록 한다.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06a
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• pp.85-87
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• 2006

압타머칩은 (주)제노프라에서 개발한 새로운 개념의 바이오칩으로서, 압타머(aptamer)를 이용하여 혈액중의 특정 단백질군의 상대적인 양의 변화를 측정할 수 있으며, 질병 진단에 바로 응용할 수 있는 도구이다. 본 논문에서는 압타머칩 데이터 분석을 통해 심혈관 질환 환자의 질병 진행 단계를 예측할 수 있음을 보인다. 정상, 안정/불안정성 협심증, 심근경색의 네 단계로 표지된 환자의 혈액 샘플로부터 제작한 (주)제노프라의 3K 압타머칩 데이터를, 일반 DNA 마이크로어레이 분석과 동일한 과정을 거쳐 분류한 결과, 각 단계별 환자샘플이 확연히 구분되는 것을 확인하였다. 분산분석 결과 P-Value를 이용하여 자질 선택을 수행하고, 분류 알고리즘으로는 신경망, 결정트리, SVM, 베이지안망을 적용한 결과. 각 알고리즘별로 50대 남성환자 31개의 샘플에 대하여 $77{\sim}100%$의 정확도로 심혈관 질환의 단계를 구분해내었다.

• Journal of Yeungnam Medical Science
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• v.3 no.1
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• pp.243-247
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• 1986

174 patients who visited in the Department of Dentistry, College of Medicine, Yeungnam University from 1983. 7. 15 to 1986. 11. 30 were surveyed on the tendency of patient distribution and the state of Angle's classification. The results were as follows : 1. There was increased visiting rate of patient per year. Female outnumbered male by a ratio of 1.3 : 1. 2. 8-15 age group was 74% in total visiting in the most frequency. The average visiting numbers of each month were higher among the vacation and was about 74% in that period. 3. As showed the living distribution, Nam Gu and Su Sung Gu's patients were 53% of the total. 4. As the motive of visiting in Dental Department, patients of 30% in total patients visited for themself to receive orthodontic treatment and others was introduced patients. 5. By classification, Class I malocclusion was 63% in total visiting patient, Class II malocclusion 17%, ClassIII malocclusion 20%. Crowding among Class I malocclusion was 60%.

• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.1-7
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• 2022

The study was conducted to determine the effectiveness of the triage training program utilizing pre-and post-training experiments designed for 119 emergency medical services teams. Objectives: This study evaluated the effectiveness of triage training programs on the accuracy of triage performed by 119 emergency medical services team staff who participated in the triage training program. Behavior: Participants in this study included 119 of the 166 EMS staff. In this program, a modified START triage consisting of a 20-minute theoretical presentation was presented to the participants. Data were analyzed using SPSS 21.0. Results: A significant increase in triage accuracy for 119 EMS teams(p<.001). And undertriage showed a significant decrease(p<.001). In addition, overtriage showed a decrease but was not statistically significant. Conclusions: The results obtained from this study showed that the triage training program was effective in improving the accuracy of the triage of multiple injury patients or disaster victims when presented to the 119 emergency medical services team. Therefore, these results suggest that it would be helpful to add triage training to the fire department's formal training program.

• The Journal of the Korean dental association
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• v.41 no.4 s.407
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• pp.230-238
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• 2003

본 연재는 상악 매복치아들의 발치술 및 발치 후 환자관리에 대한 내용을 기술하기에 앞서 매복치의 정의 및 분류, 매복치의 원인과 빈도, 매복치의 진단 및 외과적 처치법 등의 전반적인 내용에 대해 간략히 알아 본 다음 상악 매복치아 들의 발치법 및 환자관리 순으로 설명하고자 한다.