• Journal of Life Science
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• v.33 no.5
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• pp.429-435
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• 2023

Epidemiological studies suggest that maternal infection, maternal stress, and environmental risk factors during pregnancy increase the risk of brain development abnormalities associated with cognitive impairment in the offspring and increase susceptibility to schizophrenia and autism spectrum disorder. Several animal models have demonstrated that maternal immune activation (MIA) is sufficient to induce abnormal brain development and behavioral defects in the fetus. When polyinosine:polycytodylic acid (poly I:C) or lipopolysaccharide (LPS), which is commonly used in maternal immune activation animal models, was introduced into a pregnant dam, an increase in pro-inflammatory cytokines and microglial activity was observed in the offspring's brain. Microglia are brain-resident immune cells that play a mediating role in the central nervous system, and they are responsible for various functions, such as phagocytosis, synapse formation and branching, and angiogenesis. Several studies have reported that microglia are activated in MIA offspring and influence offspring behavior through interactions with various cytokines. In addition, it has been reported that they play an important role in brain circuits through interactions with neurons and astrocytes. However, there is controversy concerning whether microglia are essential to brain development or lead to behavioral defects, and the exact mechanism remains unknown. Therefore, for the potential diagnosis and treatment of brain developmental disorders, a functional study of microglia should be conducted using MIA animal models.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.128-128
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• 2023

우리나라 농업용 저수지는 저수량만을 참조하여 운영한다. 이러한 현실을 개선하기 위해, 유입량을 고정시키고 저수지 물수지 분석에 의해 방류량을 생산하는 체계를 구축했다. 2018년부터 2021년까지 총저수량 142만m³의 옥서저수지, 106만m³의 홍동저수지에 적용하여 일별로 저수량을 모의하여 관측값과 비교하고, 저수지 물수지 분석에 의해 실시간 계측되는 수로유량의 신뢰도를 평가하였다. 장기간의 계측 자료를 보유하고 있는 인근 다목적댐인 보령댐의 운영자료(2018~2021)를 이용하여 유입량 모형의 매개변수(α=3.500)를 결정하고, 저수지 유입량을 모의한 결과 NSE 0.854, R² 0.858의 높은 신뢰도를 얻었다. 유입량을 고정시키고, 저수지 물수지 분석에 의해 방류량을 계산한 결과 옥서저수지는 일최대 방류량 5.7m³/s, 일평균 0.2m³/s, 홍동저수지는 각각 5.9m³/s, 0.2m³/s로 나타났다. 총방류량을 측정 수로유량과 여수로 방류량으로 분할하고, 저수지 물수지 분석에 의해 수로유량의 신뢰도를 평가한 결과 옥서저수지는 R²가 0.771, 일평균 저수위 오차 88.6cm, 일평균 저수량 오차 9.4%, 홍동저수지는 R²가 0.086, 일평균 저수위 오차 69.9cm, 일평균 저수량 오차 18.0%로 오차가 크게 나타났다. 저수지 수위가 만수위(FWL) 이하일 때는 여수로 방류량을 0으로 하여 총방류량을 여수로 방류량과 수로유량으로 분할한 후, 물수지 분석에 의해 신뢰도를 평가한 결과, 옥서저수지의 경우 R²는 0.941, 일평균 저수위 오차 2.6cm, 일평균 저수량 오차 0.35%를 나타내, 신뢰도가 크게 증가했다. 그러나 홍동저수지의 경우는 R²는 0.521, 일평균 저수위 오차 2.2cm, 일평균 저수량 오차1.02%를 나타냈지만, 낮은 신뢰도를 보였다. 측정 수로유량의 신뢰도는 두 저수지 모두 낮게 나타났다. 수로유량 조정을 통해 옥서저수지의 신뢰도는 향상 시킬 수 있었지만 홍동저수지의 경우는 향상 시킬 수 없었다. 이는 여수토 비상수문조작 실적과 저수지 사통 수문 조작 실적이 없어, 그 결과를 정확히 반영할 수 없었기 때문인 것으로 결론을 내렸다.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.1
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• pp.85-97
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• 2023

Seoul Boramae Park was opened on May 5, 1986, after the Republic of Korea Air Force Academy relocated to Cheongju City in 1985. This study aims to examine the birth and evolution of Seoul Boramae Park and diagnose the park's value being transformed from the former site of the Air Force Academy. Policy reports and newspaper data were analyzed as a research method, focusing on Seoul public records. The study results are as follows. First, Seoul Boramae Park is a large-scale park created before the policy for parks on relocated sites we enacted. Second, Seoul Boramae Park has historical value as an urban park where memories and traces of the Air Force Academy overlap. Third, Seou Boramae Park contributed to regional change by promoting the public value of parks created on the relocated sites with an urban planning method. Seoul Boramae Park has implications for Korean landscape history as a case of securing large green areas in Seoul and presenting its function and roles as a park created on a relocated site.

• Environmental and Resource Economics Review
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• v.31 no.4
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• pp.825-848
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• 2022

This paper analyzed the factors for increasing energy consumption in the domestic manufacturing sector using the LMDI (Log mean division index) decomposition method for the period from 1999 to 2019. Among the LMDI decomposition analysis methods, both additive and multiplicative factor decomposition methods were used. in this analysis. According to the result of the analysis, the factor that increased energy consumption in the domestic manufacturing industry was the production effect, and the structure effect and intensity effect were found to be the factors that decreased energy consumption. In particular, the reduction of energy consumption due to the structure effect was greater than that of energy consumption effect due to the intensity effect. By period, it can be seen that energy consumption increased rapidly due to the production effect until 2011, but after that, the increase in energy consumption due to the production effect slowed down. On the other hand, after that, the energy reduction effect due to the structure effect and the intensity effect became prominent. In order to save energy in the manufacturing sector in the future, energy diagnosis and management through EMS (Energy management system) and FEMS (Factory energy management system) are more necessary. In addition, restructuring into a low-energy consumption industry seems more necessary.

• Journal of the Korean Society for information Management
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• v.40 no.2
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• pp.211-241
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• 2023

With rapidly changing technological implementation of operating systems of businesses, the Ministry of foreign affairs (MOFA) of the Republic of Korea (ROK) has been undergoing digital transformation to its overall operations with the intent to innovate information and knowledge management (IKM) strategies since the mid-2000s. However, assessment as to the effectiveness of implemented IKM has been inadequately analyzed. This study aims to assess the concepts and limitations of the MOFA's current IKM strategies and the methods it employs to deliver its IKM framework, in light of strengthening the organizational ambidexterity and absorptive capacity, and also fostering organizational innovation through a qualitative study that involves interviews and analysis of reports from MOFA. The MOFA's IKM possesses dynamic capabilities to adapt to changing digital technologies. However, the institution's IKM is constrained by limitations associated with the utilization of the IKM system such as a structure that handles confidential documents and a lack of a collaborative system for IKM, and external limitations such as changes in the domestic political situation governing MOFA's priorities and the hierarchy of government organizations. Consequently, developing the organizational ambidexterity and absorptive capacity was not possible. To develop an IKM framework for organizational innovation, the MOFA must devise a way to minimize the impact of external changes by overcoming internal limitations. To that end, a detailed study on the development of a practically usable IKM system should include establishing a dialogue between job groups and enhancing employee competency in preparation for a changing environment.

• Journal of Service Research and Studies
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• v.11 no.2
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• pp.67-77
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• 2021

This study is a study on the methodology of establishing an innovation strategy centering on the customer experience, which is essential in order to transform the existing collection and preservation-centered mutual aid company service into a visitor-centered service. To this end, we conducted literature research on environmental changes in the funeral industry from the perspective of service science and the significance and value of customer experiences within them, good customer experiences and bad customer experiences from the perspective of customer experience management. A study was conducted to present and prove a specific model. The customer experience-oriented innovation strategy of the funeral industry means to search for various alternatives that can reach the target state from the present state, focusing on the customer, and select the most appropriate transformation plan among them. As an effect of application, it was found that it is a source of differentiation by generating positive emotions to customers, and that customer experience data is highly helpful in making important decisions for the actual resource input of the parent company. This innovation model was presented, and its value was firstly proved by analyzing the difference from the existing evaluation method. Finally, as a result of analyzing the causal relationship through regression analysis using the customer experience measurement procedure, customer experience diagnosis/evaluation, customer experience innovation strategy, and cooperative company's performance as variables, the relationship proved to be significant.

• Journal of Service Research and Studies
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• v.11 no.1
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• pp.21-30
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• 2021

This study examined methodologies for establishing a customer experience-focused innovation strategy, which is essential to transforming existing collection and preservation-oriented museum service into a visitor-oriented service. To this end, a review of studies examining good customer experience and bad customer experience was conducted, focusing on change in museum environments and customer experience from the service science and customer experience management perspectives. Research was conducted to present and prove. Implementing a customer experience-oriented innovation strategy in a museum requires exploring the various approaches that can be used to reach the target state from the present state, focusing on the customer, and selecting the most appropriate transformation plan. This study found that effective approaches are distinguished by the fact that they generate positive emotions in customers and use customer experience data to make important decisions regarding the establishment of practical resources in museums. This innovation model was developed and validated by analyzing how it differed from existing evaluation methods. Finally, a regression analysis using the customer experience measurement procedure, customer experience diagnosis/evaluation, customer experience innovation strategy, and museum performance as variables revealed a significant causal relationship.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.17 no.2
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• pp.223-238
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• 2006

For a public library. which is a regional information service agency. to acquire high competitiveness, preparation for uncertainties of future through understanding its own internal strengths and weaknesses. and external opportunities and threats based on assessments regarding knowledge information environment and characteristics of regional community. current status of the library, etc. Therefore. in this study, through SWOT analysis. one of competitive strategy analysis methods, the status of competitive strategy of C library was analyzed. In order to carry out the study interview and survey were performed with professional librarians, then through final consultations from management consulting experts, a plan to strengthen competitiveness for C library was devised. Conclusions from this study were as below. In order to strengthen competitiveness of C library offering distinguished high quality services through active cooperations with external institutions, efforts to improve library's position and stand following being selected as a library to visit for 2006 World Library and Information Congress, and revitalization of library usage through providing user oriented differentiated services are needed.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.4A
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• pp.537-548
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• 2008

Recently, the prestressed unbonded concrete structures are increasingly being built. The mechanical behavior of prestressed concrete beams with unbonded tendon is different from that of normal bonded PSC beams in that the increment of tendon stress was derived by whole member behavior. The purpose of the present paper is therefore to evaluate the flexural behavior and to propose the equation of ultimate tendon stress by performing static flexural test according to span/depth, concrete compression strength, reinforcement ratio and the effect of existing bonded tendon. From experimental results, for cracking, yielding and ultimate load, the effect of reinforcement ratio was more effective than concrete compression strength, and the beams having high strength concrete had a good performance than having low concrete, but there was no difference between high strength and low strength. And as L/dp was larger, test beams had a long region of ductility. This means that unbonded tendon has a large contribution after reinforcement yielding. Especially, the equation of ACI-318 was not match with test results and had no correlations. After analysis of test results, the equation of ultimate unbonded tendon stress without slip was proposed, and the proposed equation was well matched with test results. So the proposed equation in this paper will be a effective basis for the evaluation of unbonded tendons without slip, analysis and design.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.3
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• pp.234-244
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• 2023

Tooth wear refers to the loss of dental hard tissue caused by various physiological and pathological causes, and excessive pathological wear can cause complications such as pathological changes in dimensions, occlusal disharmony, loss of function, and aesthetic problems. The cause of tooth wear can be caused by attrition, abrasion, corrosion and abfraction, and it is known to act in a multifactorial etiology in interocclusal activity. In patients with excessive pathological wear, it is important to determine whether or not the vertical dimension of occlusion is reduced, and complete oral rehabilitation should be achieved with the adaptation of the neuromuscular and temporomandibular joint through accurate diagnosis and analysis. The patient in this case was a 63-year-old male patient, who presented discomfort to cold beverage due to severe tooth wear. After analysis of the patient's vertical dimension of occlusion, a full mouth rehabilitation was performed with increasing vertical dimension of occlusion. The goal of treatment was to improve the occlusal plane with the equal-intensity contact of all teeth, harmonious anterior guidance and immediate disclusion of all posterior contacts. After rehabilitation, the patient was satisfied with function and esthetic appearance.