• 전기의세계
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• v.46 no.3
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• pp.20-25
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• 1997

자율주행시스템은 복잡한 환경에서 효과적인 주행을 위해서 센서를 통해 주변의 정보를 수집하고 주변환경에 적절한 동작을 취해야 한다. 이러한 자율주행시스템에 지능적인 방법을 통하여 새롭게 제안한 방법을 서술하였다. 퍼지 논리를 이용하여 운전자와 같이 차량이 차선을 따라 주행하기 위한 퍼지 논리 제어기(FLC)가 설계되었다. 함축적인 차량모델을 기반으로 설계한 퍼지 논리 제어기가 복잡하고 정확한 차량모델을 기반으로 설계된 PID나 FSLQ 제어기와 동등한 성능을 발휘하였다. 인간의 운전방법을 학습할 수 있는 신경회로망을 이용하여 자율주행시스템에 적용하였다. 퍼지 신경회로망은 인간의 제어특성을 반영하도록 설계되었으며 자동으로 생성된 제어기는 퍼지 논리 제어나 신경회로망의 기법보다 우수한 성능을 발휘하였다. 퍼지 논리, 신경회로망, 유전자 알고리즘 등의 인간의 지능 모델에 기초를 둔 방법을 자율주행차량의 제어에 도입하므로써 기존의 자율주행시스템의 문제점을 극복하는데 주요한 역할을 하였다. 앞으로 퍼지 논리, 신경회로망, 유전자 알고리즘은 각각의 강점을 융합하거나, 고전적인 제어 알고리즘과 결합하므로써 더욱 우수한 성능을 발휘할 것으로 예상된다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.5 no.5
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• pp.877-883
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• 2001

In this paper, we propose a new Genetic Algorithm(GA)-based Multiuser Detector(MUD), and its performance is evaluated by computer simulation compared to both the optimum MUD and the Hopfield neural network(NN) -based MUD when the near-far problem exists. From the results of comprehensive simulation, it is shown that the proposed MUD in this paper can guarantee a close BER performance compared to both the optimum MUD and the Hopfield NN MUD with a considerable reduced complexity under the near-far condition. Furthermore, a more performance improvement than the Hopfield W MUD can be expected when the near-far problem does not exist.

• Environmental Mutagens and Carcinogens
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• v.22 no.1
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• pp.54-59
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• 2002

We have used cDNA microarray hybridization to identify gene regulated in response to gamma-irradiation in U-937 cell. The cDNA-chip was composed entirely of 1,000 human cancer related gene including apoptosis and angiogenesis etc. In gamma-irradiated U-937 cell, highly charged protein, ribosomal protein L32, four and a half LIM domains 3, lipocalin 2 (oncogene 24p3) and interleukin 15, ataxia telangiectasia mutated (includes complementation groups A, C and D) genes showed increased level of its transcription, and cell division cycle 25A, dihydrofolate reductase, topoisomerase (DNA) II beta(180kD), kinase suppressor of ras and strarigin genes showed reduced level of its transcription compared to untreated U-937 cell. The significant change of level of transcription was not found in well-known ionizing radiation(IR)-responsive gene, such as transcription factor TP53 and p53 related gene, except ataxia telangiectasia mutated gene.

• Korean Journal of Biological Psychiatry
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• v.17 no.2
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• pp.65-69
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• 2010

Gene-environment interactions are important in pathogenesis of suicide or suicidal behavior. Twin and adoption studies and family studies show that genetic factors play a critical role in suicide or suicidal behavior. Given the strong association between serotonergic neurotransmission and suicide, recent molecular genetic studies have focused on polymorphisms of serotonin genes, especially on serotonin transporter and tryptophan hydroxylase genes. Some studies have revealed a significant interaction between s allele of the serotonin transporter gene and the risk of suicide attempt associated with childhood trauma. In addition, the polymorphism of brain-derived neurotrophic factor gene also may influence the effect of childhood trauma in relation to the risk of attempting suicide. Future studies should explore genetic and environmental factors in suicide or suicidal behavior and examine for gene and environment interaction.

• Proceedings of the Korean Information Science Society Conference
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• 2000.10b
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• pp.137-139
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• 2000

이동로봇을 위한 제어기를 개발하려는 폭넓은 연구가 진행되어 왔다. 특히, 몇몇 연구가들은 유전자 알고리즘이나 유전자 프로그래밍과 같은 진화 알고리즘을 사용하여 장애물 피하기, 포식자 피하기, 이동하는 먹이 잡기 등의 기능을 수행하는 이동로봇 제어기를 개발하였다. 이러한 연구 선상에서, 우리는 이동로봇을 제어하기 위해 셀룰라 오토마타 상에서 진화된 CAM-Brain을 적용하는 방법을 보여왔다. 그러나, 이러한 접근방법은 로봇이 복잡한 환경에서 적합한 행동을 수행하도록 만드는데 한계가 있었다. 본 논문에서는, Maes의 행동선택 방법론을 이용하여 간단한 행동을 하도록 진화된 모듈들을 결합함으로써 이러한 문제를 해결하려고 한다. 실험 결과는 이러한 접근방법이 복잡한 환경을 위한 신경망 제어기를 개발하는데 가능성이 있음을 보여주었다.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2001.05a
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• pp.244-245
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• 2001

산폐유의 농도를 l~8% 까지 단계별로 조정하여 P. aeruginosa EMS1과 mutant strain A34의 유화활성 및 생육도, 표면장력 등을 서로 비교하였다. P. aeruginosa의 경우 1%의 산폐유가 첨가되었을 때 유화활성이 가장 높았으며, 1~3%까지 유화활성이 높게 나타났으며, mutant strain의 경우 2%에서 가장 높은 유화활성 값을 나타내었고, 1~3%까지 유화활성이 높게 유지되었다. P. aeruginosa EMS1 및 mutant strain A34 모두 4% 농도에서 가장 높게 나타났다. 표면장력과 biosurfactant의 상대적인 양을 나타내는 Fcmc의 경우 P. aeruginosa EMS1 보다 mutant strain A34가 우수하게 나타났다. PCR 결과 P. aeruginosa EMS1은 rhlamnolipid의 coding 유전자인 rhlRAB gene을 가지는 것으로 확인되었다.

• Proceedings of the Korean Society of Crop Science Conference
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• 2020.11a
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• pp.132-132
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• 2020

아직까지 국내에서 GM작물이 상업화를 위해 승인된 예는 없지만 생명공학기술의 발전으로 GM작물의 개발은 급속한 증가 추세에 있다. 비의도적인 방출로 인해 미승인 LMO 목화가 전국적으로 재배되어 국립종자원 주관으로 양성 판정된 재배지의 목화를 폐기 처분하였으나(2017), GM작물이 유해하다는 인식과 환경에 방출되어 생태계를 교란시킨다는 인식이 팽배해 있는 현실에서 과학적으로 유전자의 이동성을 검증하는 노력이 중요하다. 자식성 작물의 화분의 이동성 조사를 위해 중앙의 코어 위치에 LM작물을 식재한 후 LM작물 주변에 재배품종을 심어 유전자이동 가능성을 조사하고 재배 환경에 의한 영향을 평가하기 위해 포장 주변 기상상황 데이터-온도, 습도, 풍속, 풍향, 기압, 강수량 등을 분석하고 기상상황이 화분의 전이에 미치는 영향 조사하였다.

• KSBB Journal
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• v.8 no.2
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• pp.133-142
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• 1993

The effects of genetic and environmental factors on productivity of a cloned protein were studied in recombinant Saccharomyces cerevisiae. Plasmid stability and copy level were very high for a $REP^+$ system(at ca. 10 generations, stability: 65-90%, plasmid copy number per cell: 40-200), whereas these were very low for a yep- system(at ca. 10 generations, stability: 30%, plasmid copy number per cell 20). In plasmids containing the $2{\mu}m$ circle genome, a $[cir^o]$ strain was a preferred host cell since the plasmid stability and the copy number in a $[cir^o]$ strain were higher than in a $[cir^+]$strain. Cloned gene expression was dependent on plasmid copy number and stability. The inducer (galactose) level played a very important role in cloned lacZ gene expression, showing that a galactose concentration of 0.8% was sufficient for induction of gene expression. Induction rate was very fast in the case of plasmids exhibiting high stability and copy number by a factor of 4 to 25. The time to reach the peak value of gene expression was longer when galactose was added at the start of fermentation (ca. 26 hours) than at the mid-exponential phase (ca. 6 hours). Glucose repression was reduced by a factor of 2 to 5 as the relative inducer level increased.

• Korean Journal of Plant Resources
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• v.27 no.4
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• pp.392-399
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• 2014

Plant senescence is one of the survival strategies to use limited nutrients efficiently during growth, development and adaptation. In this study, we isolated a gene (PagSEN1) homologous to SENESCENCE 1 from Populus alba ${\times}$ P. glandulosa. The PagSEN1 gene encodes a putative protein consisting of 243 amino acids containing a rhodanese domain. Southern blot analysis suggested that two copies of the PagSEN1 gene are present in the poplar genome. We characterized its transcriptional expression under various conditions mimicking senescence and environmental stresses. The PagSEN1 was expressed most strongly in mature leaves but most weakly in roots. The gene was significantly up-regulated by treatments with mannitol, NaCl, ABA and JA, but not by cold, SA and GA3. These results indicate that PagSEN1 is involved in senescence response induced by environmental stresses.

• The KIPS Transactions:PartB
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• v.12B no.4 s.100
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• pp.429-436
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• 2005

A simple stereo matching algorithm using population-based incremental learning(PBIL) is proposed in this paper to decrease the general problem of genetic algorithms, such as memory consumption and inefficiency of search. PBIL is a variation of genetic algorithms using stochastic search and competitive teaming based on a probability vector. The structure of PBIL is simpler than that of other genetic algorithm families, such as serial and parallel ones, due to the use of a probability vector. The PBIL strategy is simplified and adapted for stereo matching circumstances. Thus, gene pool, chromosome crossover, and gene mutation we removed, while the evolution rule, that fitter chromosomes should have higher survival probabilities, is preserved. As a result, memory space is decreased, matching rules are simplified and computation cost is reduced. In addition, a scheme controlling the distance of neighbors for disparity smoothness is inserted to obtain a wide-area consistency of disparities, like a result of coarse-to-fine matchers. Because of this scheme, the proposed algorithm can produce a stable disparity map with a small fixed-size window. Finally, an alterative version of the proposed algorithm without using probability vector is also presented for simpler set-ups.