Journal of the korean academy of Pediatric Dentistry
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v.50
no.2
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pp.131-141
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2023
Dental caries is a multifactorial disease influenced by interactions between teeth, biofilm, dietary factors, and various biological, behavioral, sociocultural, and genetic factors. Recent research has shown that dental caries results from dysbiosis, an imbalance in the oral microbial community, shifting the concept from an infectious disease to a non-communicable disease (NCD). Dental caries shares similarities with other chronic NCDs such as cardiovascular diseases and diabetes, as they all relate to dietary intake, lifestyle habits, and environmental factors. Considering the high prevalence of dental caries and its impact on people's health and quality of life, it is important to understand dental caries as an NCD and develop effective oral health management strategies. Ecological prevention methods and efficient public health policies should be provided to reduce risk factors associated with dental caries.
Objectives: The objectives of this study are to estimate the inhalation exposure level of benzene for workers using Tier 1 exposure models ECETOC TRA (European Center for Ecotoxicology and Toxicology of Chemicals Target Risk Assessment) and Stoffenmanager, and to investigate their reliability for exposure assessment in K-REACH. Methods: Two exposure scenarios, 'manufacture of benzene' and 'use as solvents,' were developed for assessment of workers' exposure to benzene. The Process Category (PROC) for ECETOC TRA was collected from the European Chemical Agency (ECHA) registration dossier, and the Activity for Stoffenmanager was converted from PROC using translation of exposure models (TREXMO). The information related to exposure, such as working duration, Respiratory Protective Equipment (RPE), Local Exhaust Ventilation (LEV), and Risk Management Measure (RMM) were classified into high, medium, and low exposure conditions. The risk was determined by the ratio of the estimated exposure and occupational exposure limits of benzene. Results: Under high exposure conditions, the worker exposure level calculated from all PROCs and Activities exceeded the risk level, with the exception of PROC 1 and Activity 1. In the medium exposure condition, PROC 8a, 8b, and 9 and Activity 3, 7, and 8 all exceeded the risk, whereas in the low condition, all PROCs and Activities were determined to be safe. As a result, action corresponding with the low exposure condition is required to reduce the risk of exposure among workers in workplaces where benzene is manufactured or used as a solvent. In addition, the predicted exposure levels derived from the exposure models were lower than measured levels. The exposure levels estimated from Stoffenmanager were more conservative than those from ECETOC TRA. Conclusions: This study demonstrates the feasibility of exposure models for exposure assessment through the example of occupational inhalation exposure assessment for benzene. For more active utilization of exposure models in K-REACH, the exact application of collected information and accurate interpretation of obtained results are necessary.
Park, Hye-Jin;Ko, Kwang-Yong;Han, Kook-Tak;Kim, Il-Jung;Lee, Yong-Jae;Kim, Sung-Hun;Lee, Kyu-Seung
Korean Journal of Agricultural Science
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v.32
no.2
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pp.215-221
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2005
The residual study of pesticide has been used in various areas, such as food safety, environmental protection, establishment of tolerance, and explaining the pathway and reaction mode of pesticides, and its importance was expected to increase further more. The aspect of food safety, the pesticide residue survey have been practiced at many organizations, but there were no verification of analytical results at present. In this experiment, we focused on instrumental stability, including response of each instrument and the recovery ratio of each organization's method. As samples for this experiment, we prepared cucumber and sesame, and chose 4 pesticides (bifenthrin, chlorpyrifos, diazinon, and ethoprophos), which were mostly detected from pesticide residue survey and widely used for each crop. The standard deviation of peak areas in the chromatogram of each pesticide were under 1.212 %, so it showed that most instruments were stable. The relationship of recovery ratio of each organization were over 0.996 for every pesticide and each organization. Finally, the analytical results for pesticide residue from each participated organization were not statically significant and we could put confidence in the result from each organization.
Objectives: We aimed to develop a measurement method of five metabolites of trichloroethylene (TCE) in a concurrent biological sample, e.g., trichloroacetic acid (TCA), dichloroacetic acid (DCA), S-(1,2-dichlorovinyl) glutathione (DCVG), S-(1,2-dichlorovinyl)-L-cysteine (DCVC), and N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (NAcDCVC) and to validate the method before application to pharmacokinetic study. Methods: TCE metabolites were simultaneously analyzed using high performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS/MS) with as little as 50 ${\mu}L$ of serum and urine. DCA, TCA and NAcDCVC were extracted with diethyl ether, while DCVC and DCVG were extracted by solid phase extraction. This method was validated according to the guidelines for bioanalytical method validation of the Korean National Institute of Toxicological Research. Then, we determined the five metabolites in five strains of mice at 24 hr after exposure to 1 g TCE /kg body weight. Results: The limits of detection for the five metabolites in biological samples ranged from 0.001 to 0.076 nmol/mL, which is comparable to or better than those previously reported. Most calibration curves showed good linearity ($R^2=0.99$), and between-batch variation was less than 20% expressing acceptable robustness and reproducibility. Using this method, we found TCA and DCA were detected in all test mice at 24 hr after the oral administration while NAcDCVC and DCVC were detected in some strains, which showed strain-dependent metabolism of TCE. Conclusions: The present method could provide robust and accurate measurements of major key metabolites of TCE in biological media, which allowed concurrent analysis of TCE metabolism for limited amounts of biospecimens.
Journal of the Korea Academia-Industrial cooperation Society
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v.20
no.5
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pp.137-144
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2019
The purpose of this study is to investigate the relationship between the perception of dying with dignity and the quality of life based on the opinions of the Korean populations. The participants were selected using a stratified proportional allocation method and 1,000 adults aged between 19 and 74 years from 17 municipalities and provinces in Korea. The questionnaire consisted of 2 demographic items; 26 items on the quality of life scale; and 57 items on the perception of dying with dignity. The statistical methods used included frequency analyses, independent sample t-tests, and correlation analyses. The results showed that the quality of life was highest for the social life quality item, and that the participants who had experienced a death in the family were more likely to have statistically lower quality of life in physical, psychological, environmental, and social areas. In terms of the participants' perception on dying with dignity, the score for death preparation was the highest; specifically, the score for psychological/economic burden reduction was the highest. The quality of life of the participants showed a positive correlation in all aspects of the perception of dying with dignity: physical symptoms and control, death preparation, death environment, family and social relations, hospital treatment, psychological dignity, and spirituality. Other studies conducted with middle-aged populations showed that their quality of life was higher when they perceived the acceptance of death is important and were willing to participate in death preparation education. Therefore, in order to improve the quality of life and have a positive influence on the participants, educational programs on death preparation and dying with dignity considering all the areas of the perception of dying with dignity should be provided.
The purpose of this study was to attempt to lay the foundation for the development of oral health programs geared toward promoting the oral health of low socioeconomic class children. The subjects in this study were 257 school children who used local children's centers. The findings of the study were as follows: 1. The children mean scored 5.74 on oral health knowledge. 2. In terms of oral health awareness, 47.1% viewed the right toothbrushing as the best way to stay away from dental caries. 3. 45% of the subjects reported toothbrushing at least three times daily. 21.4% visited dental institutions three or more times in the past year. 33.1% had never undergone application of fluoride. 30.4% had never received oral health education. 4. The mean level of caries was 4.61 dft index in 1-2th grade, 3.27 DMFT index in 5-6th grade, 1.47 DMFT index in the 3-4th grad and 1.19 DMFT index in the 1-2th grade. 5. The mean level of Patient Hygiene Performance (PHP index) was 3.59, and there was no significant association was pound between PHP index and grade. 6. Oral health behavior wasn't affected by their oral health awareness, and knowledge.
Journal of agricultural medicine and community health
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v.31
no.1
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pp.21-34
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2006
Objectives: The purpose of this study was to investigate the knowledge, attitude and practice toward sanitary administration of the new restaurateurs, to carry out the sanitary management of business for improvement of sanitary level, and to provide basic data which were necessary for sanitary education of the restaurateurs. Methods: The self-recording survey on the attitude and the knowledge toward the sanitation, the sanitary administration, and its education was conducted against new 393 restaurateurs by the administrative division of Gwangju city in charge of the food industry which put in the regular sanitary education annually for the new restaurateurs. Results: In regard to food sanitation, some 87.9% to 94.4% got the right knowledge about the reason and precaution of food poisoning, storage methods of frozen or cold food, and the disposal of product after expiration of validity term. But it was about 56.0% to 63.0% who knew right about the cause and the major precaution of food poisoning, storage temperature in the refrigerator. 30.6% of the subject placed an emphasis on personal sanitation of the workers as the most important thing in the sanitary management. 83.6% replied that it was necessary to improve the sanitary level. Concerning the health examination, 78.3% replied it was needed. 76.4% pointed the need for education, but respondents with higher educational level less emphasized its needs. It was most frequently pointed out by 71.6% restaurateur's poor awareness about it. 36.7% indicated the environmental sanitation like facilities in the restaurants as the first thing to be improved. The rate of personal sanitation was 43.7%. Conclusions: To improve the poor sanitary conditions of the food service business, it was recommended to offer institutional backing and financial aid from administrative office, to encourage restaurateurs to take pride in their job, and to conduct the sanitary education effectively by the technical education institution.
Journal of Korean Society of Environmental Engineers
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v.36
no.2
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pp.127-138
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2014
As increasing concerns about potential risks and hazards in children's products, the laws and regulations for heavy metals and phthalate retardants contained in the children's products have been reinforced in many countries. Especially, in Korea, environment and health laws and regulations for children's products was declared in 2009. This study was researched in terms of contents and migration of phthalates and heavy metals in 124 children's products sold in the Korean market. The results for contents of heavy metals showed that 123 products contained different 14 heavy metals depending on kinds of products. As the results of migration by sucking, the heavy metals in the products such as black, plastic dolls, wood toys, and bottom mat for swimming were transferred into extraction solution. Ba, Cu, Zn, and Sn were transferred from most of these products into the extraction solution and Co, Ni and Pb were additionally transferred into several products. As the results of migration through a skin, while Ba, Cu, and Zn were transferred from most products containing the heavy metals, as for accessories, Cr, Ba, Ni, Zn, and Cu were migrated. The results of contents of phthalates presented that 21 products contained DBP, DEHP and DINP. Only 2 products showed the migration of DEHP by sucking. DEHP in most products were transferred and DBP for 2 products and DINP for 7 products were migrated.
This study examines the assessment systems of LEED v4.1, an eco-friendly building evaluation system in the United States, and SITE v2, an assessment system for sustainable outdoor spaces, and then compares and examines them from the perspective ofrelevant laws and institutional guidelines and standards in Korea. The conclusion is as follows. First, the US eco-friendly certification system basically not only establishes an independent evaluation system according to the field of expertise, but also provides a sustainable city and community through response to the climate crisis and the comfort of the external space environment. It can be evaluated that securing the quality of life of healthy and happy city dwellers is the top priority. Second, Korea's Green Building Certification System (G-LEED) was basically based on the American LEED system, but it was judged that there was a fundamental difference. It was judged that there is a limitation in not being able to achieve an integrated approach through the participation of various expert groups and stakeholders, but also in the accumulation of more scientific and reliable data and information through the application of cutting-edge information and communication equipment. Third, in the case of external space in Korea, a sustainable assessment system has not been established, and not only is it dispersed in various legal and institutional guidelines, but also its effectiveness is judged to be very low. Therefore, it is judged that it is urgent to introduce and secure the applicability of SITES v2, a sustainable outdoor space assessment system in the United States. It was judged that the effectiveness should be secured through the upward adjustment of the minimum Ecological Area Ratio.
Eunju Kim;Tae-Mun Hwang;Jae-Wuk Koo;Jaeyong Song;Hongkyeong Park;Sookhyun Nam
Journal of Korean Society of Water and Wastewater
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v.37
no.6
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pp.425-435
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2023
Organoleptic parameters such as color, odor, and flavor influence consumer perception of drinking water quality. This study aims to evaluate the taste of the selected bottled and tap water samples using an electronic tongue (E-tongue) instead of a sensory test. Bottled and tap water's mineral components are related to the overall preference for water taste. Contrary to the sensory test, the potentiometric E-tongue method presented in this study distinguishes taste by measuring the mineral components in water, and the data obtained can be statistically analyzed. Eleven bottled water products from various brands and one tap water from I city in Korea were evaluated. The E-tongue data were statistically analyzed using multivariate statistical tools such as hierarchical clustering analysis (HCA), principal component analysis (PCA), and partial least squares discriminant analysis (PLS-DA). The results show that the E-tongue method can clearly distinguish taste discrimination in drinking water differing in water quality based on the ion-related water quality parameters. The water quality parameters that affect taste discrimination were found to be total dissolved solids (TDS), sodium (Na+), calcium (Ca2+), magnesium (Mg2+), sulfate (SO42-), chloride (Cl-), potassium (K+) and pH. The distance calculation of HCA was used to quantify the differences between 12 different types of drinking water. The proposed E-tongue method is a practical tool to quantitatively evaluate the differences between samples in water quality items related to the ionic components. It can be helpful in quality control of drinking water.
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