• Title/Summary/Keyword: 확실 인자 추정

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Studies on the Efficiency of Selection of Some Agronomic Characteristics in Accelerating Generations of Hybrid-Rice Population (수도육종년한단축법에 있어서 몇가지 형질의 선발효과에 관한 연구)

  • Chea-Yun Cho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.20
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    • pp.27-62
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    • 1975
  • These studies were aimed at clarifying whether or not selecting agronomic characteristics of hybrid-rice populations under greenhouse conditions was useful. The selection of two quantitative characteristics, culm length and heading date, and two qualitative characteristics, shattering and awnedness, was very effective, but the flag leaf length and the exsertion of panicle was not consistent, varying from one cross to another.

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GIS-based Spatial Integration and Statistical Analysis using Multiple Geoscience Data Sets : A Case Study for Mineral Potential Mapping (다중 지구과학자료를 이용한 GIS 기반 공간통합과 통계량 분석 : 광물 부존 예상도 작성을 위한 사례 연구)

  • 이기원;박노욱;권병두;지광훈
    • Korean Journal of Remote Sensing
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    • v.15 no.2
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    • pp.91-105
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    • 1999
  • Spatial data integration using multiple geo-based data sets has been regarded as one of the primary GIS application issues. As for this issue, several integration schemes have been developed as the perspectives of mathematical geology or geo-mathematics. However, research-based approaches for statistical/quantitative assessments between integrated layer and input layers are not fully considered yet. Related to this niche point, in this study, spatial data integration using multiple geoscientific data sets by known integration algorithms was primarily performed. For spatial integration by using raster-based GIS functionality, geological, geochemical, geophysical data sets, DEM-driven data sets and remotely sensed imagery data sets from the Ogdong area were utilized for geological thematic mapping related by mineral potential mapping. In addition, statistical/quantitative information extraction with respective to relationships among used data sets and/or between each data set and integrated layer was carried out, with the scope of multiple data fusion and schematic statistical assessment methodology. As for the spatial integration scheme, certainty factor (CF) estimation and principal component analysis (PCA) were applied. However, this study was not aimed at direct comparison of both methodologies; whereas, for the statistical/quantitative assessment between integrated layer and input layers, some statistical methodologies based on contingency table were focused. Especially, for the bias reduction, jackknife technique was also applied in PCA-based spatial integration. Through the statistic analyses with respect to the integration information in this case study, new information for relationships of integrated layer and input layers was extracted. In addition, influence effects of input data sets with respect to integrated layer were assessed. This kind of approach provides a decision-making information in the viewpoint of GIS and is also exploratory data analysis in conjunction with GIS and geoscientific application, especially handing spatial integration or data fusion with complex variable data sets.

Thermal Characteristics of Men's Suit Ensembles (남성용 정장의 온열특성 연구)

  • Song, Min-Kyu;Jeon, Byung-Ik
    • Fashion & Textile Research Journal
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    • v.1 no.3
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    • pp.264-274
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    • 1999
  • The thermal resistance of 60 men's suits for summer and winter was measured to determine their thermal characteristics and physical properties, including air permeability, weight, and thickness of the jackets and trousers consisted of the ensembles were measured to predict the thermal resistance of garments and ensembles. In this study, general physical properties of the men' suit ensembles were determined. In general, thickness and weight of winter ensembles were greater than those of summer ensembles. A factor which could distinguish the difference between summer and winter ensembles was the air permeability. The air permeability of summer ensembles was 3~6 times greater than those of winter ensembles. For the thermal characteristics, the thermal resistance of winter ensembles were higher than those of summer ensembles. When the wind was involved, the thermal resistance of both ensembles decreased up to 30%. In addition, the equations were developed to predict the thermal resistance of the garments and ensembles when there was no air velocity and the thermal resistance of the ensembles with air velocity of 1.2 m/sec. Looking at the equations, thickness, weight, and size of the garments were the definite factors that affect the thermal resistance of the samples.

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Genetic Analysis of Pigmentation Pattern in the Leopard Danio (Leopard danio 반문의 유전 양상과 생존율에 미치는 영향)

  • 이병문;강거영;송춘복
    • Journal of Aquaculture
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    • v.11 no.3
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    • pp.353-361
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    • 1998
  • Genetic analysis of body pigmentation pattern has been conducted by the reciprocal monohybrid and back crosses using the wild type zebrafish, Danio rerio, and its aquarium morphs (mutants), leopard danio. Also, the effect fo pigmentation mutation was investigated with regard to the survival rates of eggs and larvae for the first 15 days after fertilization. As a result, the pattern pigment distribution was inherited by a single gene having two alleles, and which was basically followed by the principle of dominace and segregaion in Mendelian inheritance. A locus for pigment pattern turned out to be located on an autosomal chromosome. Average survival rates estimated from the various crosses between, and within, wild type zebrafish and leopard danio were as follows ; they were 80.6${\pm}$4.8% from the crosses within leopard danios ($L{\times}L$), 70.6${\pm}$4.2% between leopard female and wild type male ($L{\times}Z$), 73.2${\pm}$2.0% between wild type female and leopard male ($Z{\times}L$), and 83.8${\pm}$6.7% within wild type zebrafish ($Z{\times}Z$). These results indicated that the leopard danio, which were reported as an "aquarium morph" several decades ago and also known as a mutant in pigmentation pattern of the wild type zebrafish, seemed to be genetically stable like the wild type of zebrafish.zebrafish.

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Molecular Genetic Analysis of Behcet's Disease in Korean (한국인 베체트 환자의 분자유전학적 연구)

  • Park, Sang-Bum;Nam, Youn-Hyoung;Park, Su-Min;Lee, Sang-Hyun;Ahn, Young-Chang;Cho, Min-Ho;Kim, Jong-Gyu;Choi, Jae-Gu;Kim, Seong-Kyu;Jang, Won-Cheoul
    • Journal of the Korean Chemical Society
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    • v.51 no.6
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    • pp.536-542
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    • 2007
  • Behcet's disease (BD) is a chronic inflammatory disorder, involving several organs. Inflammation in the disease is thought to be mediated by cytokines derived from T-helper type 1 (Th1) lymphocytes. Although the exact pathogenesis for BD is not completely understood, it has been suggested that the disease is triggered in genetically susceptible individuals by environmental factors, such as microbial agents. It is noted that multiple genes, including MHC (major histocompatibility complex) and non-MHC genes, are implicated in the pathogenesis of BD. This study tries to determine whether HLA-B51, IL-18, SLC11A1 and TNF-α polymorphisms are associated with susceptibility to Behcet's disease in Koreans. As a results, HLA-B51 was a genetic factor with the strongest association with BD. But it is still uncertain whether this HLA molecule is directly involved in the pathogenesis of BD. Although the IL-18 gene polymorphisms were not associated with a susceptibility to BD in the Korean population, the patients carrying the GG genotype at position 137 had a higher risk of developing the ocular lesions. This study suggests that the allele 3 and the genotype allele 3 / allele 3 of 5'-promoter (GT)n polymorphism in the SLC11A1 gene may have a protective effect for the development of BD in the Korean population. There were no evidences for genetic association conferred by the TNF-α gene with respect to susceptibility to BD.

Clinical Observations on 12 Children with Alport Syndrome (Alport 증후군 환아 12명의 임상적 고찰)

  • Bae Young-Min;Kim Seoung-Do;Kang Hyeon-Ho;Cho Byoung-Soo
    • Childhood Kidney Diseases
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    • v.4 no.1
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    • pp.48-56
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    • 2000
  • Purpose: Alport SD., the most common herectitary rephriris, is a renal disease with rapid progression. Deafness, ocular abnormalities and a specific EM finding may be associated in addition to a family history. We have aralyged retrospectively. Methods: We observed 12 children with Alport syndrome who were diagnosed at Dept. of pediatrics in Kyunghee Univ., College of Medicine, from Apr. 1991 until Jun. 1999. We used four criteria for diagnosis: renal disease, family history, deafness or eye abnormalities, and a specific finding in electron microscopy Results: 2 of 12 patients had all features of the four diagnostic criteria. We could not trace an exact family history in 3 patients, and 6 patients did not exhibit deafness or eye abnormality. One could not have renal biopsy because offer chronic renal failure. Other three criteria were observed in her. The ratio of male to female observed was 1:2 respectively and the mean age of initial renal symptom was 5.6 years. 9 of 12 patients had a family history of renal disease. In the audiogram and ocular examination for 11 of 12 cases, sensorineural hearing loss was observed in 6 and ocular abnormality in 2 cases. In electron microscopic finding, irregular thickness of the capillary basement membranes with lamination of lamina densa and foot process obliteration was noted in 9 of 11 and thin basement membrane with splitting and foot process obliteration was noted in the other 2. The mean period of follow-up was 3 6/12 years. And one patient developed the chronic renal failure until now and had kidney transplantation. Conclusion: For the diagnosis of Alport syndrome, the following four diagnostic criteria are very important : renal disease, family history, deafness or eye abnormalities, and a specific finding on electron microscopy. We expect that more patients can be detected through the analysis of these characteristics.

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Soil Erosion Risk Assessment in the Upper Han River Basis Using Spatial Soil Erosion Map (분포형 토양침식지도를 이용한 한강상류지역 토양유실 위험성 평가)

  • Park, Chan-Won;Sonn, Yeon-Kyu;Zhang, Yong-Seon;Hong, S.-Young;Hyun, Byung-Keun;Song, Kwan-Cheol;Ha, Sang-Keun;Moon, Young-Hee
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.6
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    • pp.828-836
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    • 2010
  • This study was conducted to evaluate soil erosion risk with a standard unit watershed in the upper Han river basin using the spatial soil erosion map according to the change of landuse. The study area is 14,577 $km^2$, which consists of 10 subbasins, 107 standard unit watersheds. Total annual soil loss and soil loss per area estimated were $895{\times}10^4\;Mg\;yr^{-1}$ and 6.1 Mg $ha^{-1}\;yr^{-1}$, respectively. A result of analysis with a subbasin as a unit showed that annual soil losses and soil loss per area in Namhan river basins was more than in Bukhan river ones. Predicted annual soil loss according to the landuse ranked as Forest & Grassland > Upland ${\gg}$ Urban & Fallow area > Paddy field > Orchard. Upland area covered 6.2% of the study area, but the contribution of total annul soil loss was 40.6% and that of Forest & Grassland was 44.2%. As a evaluation of soil erosion risk using the spatial soil erosion map, we could precisely conformed the potential hazardous region of soil erosion in each unit watersheds. The ratio of regions, graded as higher "Moderate" for annual soil loss, were respectively 8.7%, 7.9% and 7.8% in 1001, 1002 and 1003 subbasins in Namhan river basin. Most landuse of these area was upland, and these area is necessary to establish soil conservation practices to reduce soil erosion based on the field observation.

Potential Roles of Hedgehog and Estrogen in Regulating the Progression of Fatty Liver Disease (지방간 진행 조절에 대한 헤지호그와 에스트로겐의 잠재적 역할)

  • Hyun, Jeong-Eun;Jung, Young-Mi
    • Journal of Life Science
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    • v.21 no.12
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    • pp.1795-1803
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    • 2011
  • Non-alcoholic fatty liver disease accompanies the rise in the prevalence of obesity, diabetes and the tendency toward high-fat dietary habits. Specifically, the higher prevalence of non-alcoholic fatty liver disease in men and postmenopausal women seems to be caused by the protective effects of estrogen against liver fibrosis, or lack thereof. There are no effective preventive therapies for liver diseases because the mechanisms underlying the progression of fatty liver diseases to chronic liver diseases and the protective effects of estrogen against fibrogenesis remain unclear. Recently, it has been reported that the hedgehog signaling pathway plays an important role in the progression of chronic liver diseases. Hedgehog, a morphogen regulating embryonic liver development, is expressed in injured livers but not in adult healthy livers. The level of hedgehog expression parallels the stages of liver diseases. Hedgehog induces myofibroblast activation and hepatic progenitor cell proliferation and leads to excessive liver fibrosis, whereas estrogen inhibits the activation of hepatic stellate cells to myofibroblasts and prevents liver fibrosis. Although the mechanism underlying the opposing actions of hedgehog and estrogen on liver fibrosis remain unclear, the suppressive effects of estrogen on the expression of osteopontin, a profibrogenic extracellular matrix protein and cytokine, and the inductive effects of hedgehog on osteopontin transcription suggest that estrogen and hedgehog are associated with liver fibrosis regulation. Therefore, further research on the estrogen-mediated regulatory mechanisms underlying the hedgehog-signaling pathway can identify the mechanism underlying liver fibrogenesis and contribute to developing therapies for preventing the progression of fibrosis to chronic liver diseases.

Experimental Studies on the Antitumor Effects of Jinryungtang Gagambang Extract (진령탕가감방의 항종양효과(抗腫瘍效果)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Jeong, Jun-Tak;Moon, Goo;Moon, Suk-Jae
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.4 no.1
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    • pp.37-53
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    • 1998
  • The sprig of Jinryungtang Gagambang has been used for curing as a traditional medicine without any experimental evidence to support the rational basis for their clinical use. This experiment was carried out to evaluate the possible therapeutic or antitumoral effects of Jinryungtang Gagambang extract against cancer, and to study some mechanisms responsible for its effect. The cytotoxic and antitumor effects were evaluated on human cell liens (A549, hep3B, Caki-1, Sarcoma 180) after exposure to Jinryungtang Gagambang extract using in ILS, colony forming efficency and SRB assay which were regarded as a valuable method for cytotoxic and antitumor effects of unknown compound on tumor cell lines. The results obtained in this studies were as follows. 1. As a result of exposure to Jinryungtang Gagambang extract, the proliferation of A549, hep3B, Caki-1, good correlations were shown from the results of SRB assay and those of clogenetic assay. 2. The oral administration of Jinryungtang Gagambang extract showed significant effects of increase of MST(mean survival time) and ILS(increased life span) depending on the increasing concentration. 3. Against squamous cell carcinoma induced by MCA, Jinryungtang Gagambang decreased not only the frequency of tumor production but also the number and weight of tumors per tumor bearing mice(TBM). Jinryungtang Gagambang also significantly suppressed the development of 3LL cell-implanted tumors by frequency and their size, and some developed tumors were regressed by the continuous treatment of Jinryungtang Gagambang extract into TBM. 4. Jinryungtang Gagambang extract also increased NK cell activities. According to the above results, it could be suggested that Jinryungtang Gagambang extract has prominent antiutmor effect.

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