• Title/Summary/Keyword: 확산방출

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A Model for Diffusion and Dissolution Controlled Drug Release from Dispersed Polymeric Matrix (고분자 분산 매트릭스로부터의 약물방출에 관한 확산 및 용출 제어 모델)

  • Byun, Young-Rho;Choi, Young-Kweon;Jeong, Seo-Young;Kim, Young-Ha
    • Journal of Pharmaceutical Investigation
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    • v.20 no.2
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    • pp.79-88
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    • 1990
  • A numerical model for diffusion and dissolution controlled transport from dispersed matrix is presented. The rate controlling process for transport is considered to be diffusion of drug through a concentration gradient coupled with time-dependent surface change and/or disappearance of the dispersed drug in response to the dissolution. The transport behavior of drug was explained in terms of ${\nu}$ parameter: ${\nu}$ value means a ratio of diffusion time constant and dissolution time constant. This general model has wide range of application from where release is controlled by the diffusion rate to where release is governed by the dissolution rate. Based on this model, theoretical drug concentration, particle size distributions in the polymer matrix system and the resulting release rate were also investigated.

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Surface Heat Water Simulation Using Depth-Integrated Model Incorporating Near Field Characteristics (근역특성이 고려된 수심적분모형을 이용한 표층온배수모의)

  • 서승원;김덕호
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.8 no.1
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    • pp.18-27
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    • 1996
  • Efforts are concentrated onto effective simulation of surface discharged heat water in two-dimensional depth-averaged finite element model using Gaussian puff algorithm incorporating near-field characteristics as patches computed from CORMIX3 with ambient flow variations. Concise analyses of horizontal and vertical temperature distributions are made for real coastal power plant discharges through four field observations and the results from this proposed method are in good agreements with observations in far-field as well as near-field. Thus, this method can simulate the heat dispersion effectively for the whole region since the complex jet momentum characteristics and ambient flows are easily represented in 10 meters of finite element discretization around a discharging point.

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A study on the dielectric and electrical conduction properties of$(Sr_{1-x}.Ca_x)TiO_3$ grain boundary layer ceramics ($(Sr_{1-x}.Ca_x)TiO_3$입계층 세라믹의 유전 및 전기전도특성에 관한 연구)

  • 최운식;김충혁;이준웅
    • Electrical & Electronic Materials
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    • v.8 no.5
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    • pp.611-618
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    • 1995
  • The (Sr$_{1-x}$ .Ca$_{x}$)TiO$_{3}$+0.6[mol%]Nb$_{2}$O$_{5}$ (0.05.leq.x.leq.0.2) ceramics were fabricated to form semiconducting ceramics by sintering at about 1350[.deg. C] in a reducing atmosphere(N$_{2}$ gas). Metal oxides, CuO, was painted on the both surface of the specimens to diffuse to the grain boundary. They were annealed at 1100 [.deg. C] for 2 hours. The 2nd phase formed by thermal diffusing from the surface lead to a very high apparent dielectric constant. According to increase of the frequency as a functional of temperature, all specimens used in this study showed the dielectric relaxation, and the relaxation frequency was above 106 [Hz], it move to low frequency with increasing resistivity of grain. The specimens showed three kinds of conduction mechanisms in the temperature range 25-125 [.deg. C] as the current increased: the region I below 200 [V/cm] shows the ohmic conduction. The region rt between 200 [V/cm] and 2000 [V/cm] can be explained by the Poole-Frenkel emission theory, and the region III above 2000 [V/cm] is dominated by the tunneling effect.fect.

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A Study on the Analysis of Combustion Gases in the Car Interiors (차량 내장재의 연소생성가스 분석 연구)

  • Kim, Hae-Rim;Park, Young-Ju;Lee, Seung-Chul;Lee, Hae-Pyeong
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 2010.10a
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    • pp.354-357
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    • 2010
  • 현대 사회에서 차량은 널리 보급되어 있으며, 일상생활에서 없어서는 안 될 필수품이 되어 있다. 그러나 자동차의 증가와 함께 차량화재 및 교통사고 등과 같은 문제점들도 함께 늘고 있는 실정이다. 2009년 기준, 1년 동안의 전체 화재발생건수 47,071건 가운데 차량 화재의 발생건수가 5,958건으로 전체의 12.6% 정도를 차지하였다. 특히 차량 내장재의 주 재질은 가연성을 지닌 열가소성 합성수지들로서 화재가 발생하였을 경우, 다량의 가연성 가스 및 독성가스를 방출하기 때문에 인명 및 재산 피해를 증가시키는 문제점을 갖고 있다. 화재 시 발생하는 독성가스는 짧은 시간에 주변으로 확산되어 인명피해에 치명적인 영향을 준다. 따라서 본 연구에서는 차량에 대한 화재위험성을 다각적으로 평가하기 위해서 연소생성가스에 주안점을 두고 연구를 수행하였다. 연구결과를 살펴보면, 차량내장재의 연기밀도는 624~172, 독성지수는 13.7~2.9인 것으로 나타났다.

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The Real Scale Fire Test for Unit Space in Apratment housing (공동주택의 단위공간 실물화재실험)

  • Yoo, Yong-Ho;Kweon, Oh-Sang;Kim, Heung-Youl
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 2009.04a
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    • pp.346-351
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    • 2009
  • 본 연구에서는 화재시 많은 인명피해가 예상되는 공동 주택을 대상으로 단위공간별 화재 성상을 예측하기 위한 실물화재실험을 실시하였다. 구성된 실물화재모델은 비교적 가연물량이 많은 침실과 화재 발생 위험도가 높은 주방을 대상으로 하였으며, 실험 모델에 구성된 단위품목은 일반주택의 가연물을 선조사 한 후 선정하였다. 실험결과 침실의 경우 점화 후 약 5분이 경과되었을 때 플래쉬오버 상태에 이르게 되어 매우 급격한 성장을 보였으며, 최대 열방출율 약 7433.3 kW, 최대 일산화탄소 578.6 ppm, 최대 이산화탄소 1.25ppm, 내부 최대온도 1350$^{\circ}$로 측정 되었다. 특히, 화재 발생 초기에 가연 공간에서 화재의 진화가 이루어지지 않으면 약 3분 내에 인체에 급격한 피해를 줄 수 있는 한계온도 이상으로 화재가 성장하기 때문에 신속한 초기 대응이 필요함을 확인하였다. 이러한 실물화 재실험에서 얻어낸 결과는 향후 화재확대 예측 시뮬레이션 결과와 비교함으로써 각 용도별 공간에서의 화재 확산 예측에 적용 될 수 있을 것이다.

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A Study on certification plan on Radio Frequency Identification for Airplane Use (항공산업에 활용되는 무선인식 기반 시스템 인증 방안)

  • Han, Sang-Ho
    • Aerospace Engineering and Technology
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    • v.7 no.1
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    • pp.236-244
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    • 2008
  • The evolution and application of RFID technologies have been at the forefront of allowing aviation industries to improve the quality of aircraft maintenance and air cargo handling. However, safety problems in airplane operation are arising from the hazards of frequencies transmitted due to RFID systems. Though the intensities of frequencies back-scattered from the tags are very weak, some malfunctions are anticipated due to induction coupling on aircraft wiring. Therefore, safety assessment such as electromagnetic compatability should be accomplished upon aircraft critical and essential equipments before installations.

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Fresh Water Flume Analysis Using an Unstructured Grid Ocean Circulation Model (비정규격자계 해양순환 모델을 이용한 하구에서의 담수 유출분석)

  • Hwang, Jin-Hwan;Park, Young-Gyu
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.12 no.4
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    • pp.227-234
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    • 2009
  • Using a finite volume ocean circulation model based on an unstructured grid (FVCOM), we studied the structure of a fresh water bulge that influences on the Region Of Freshwater Influence. Fresh water discharged a river forms a coastal boundary current to the righthand side and a cyclonically circulation freshwater bulge that grows with time. In the middle of the bulge, vertical motions bring fresh water to the bottom. When tidal motions are included, the bulge disappears while the boundary currents becomes wider. Through a simple comparison of areas occupied low salinity water we quantified vertical and horizontal mixing due to the tide and showed that the tidal motion enhances the vertical mixing. During the first few tidal cycles right after the onset of the river discharge, due to tidal excursion the horizontal mixing becomes stronger. The vertical mixing by the tide mixes the fresh water After a certain time the water around the river mouth is well mixed and the horizontal excursion of the fresh water near the river mouth does not have much effect on the horizontal mixing. When there is no tidal motion horizontal mixing is mainly by the inertial instability at the surface and the horizontal mixing becomes stronger over time.

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Investigation of Pyroprocessing Concept and Its Applicability as an Alternative Technology for Conventional Fuel Cycle (고온전해분리 기술의 개요 및 기존 핵연료주기 대체 기술로서의 적합성 검토)

  • Yoo, Jae-Hyung;Lee, Byung-Jik;Lee, Han-Soo;Kim, Eung-Ho
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.5 no.4
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    • pp.283-295
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    • 2007
  • The technical feasibility of a pyroprocessing of PWR spent fuels to recover nuclear fuel materials, uranium and transuranic elements group(TRU), was examined in this study. Also its applicability as a new fuel cycle technology in terms of non-proliferation was investigated. First, various unit processes were combined to a pyroprocess. Then the flow aspects of such materials of issue as uranium, transuraniums, rare earth, noble metals and heat generating elements were examined on the flowsheet, which was obtained by the assumptions on the basis of various experimental results in this work or separation data collected from literatures. Consequently, the calculated results of the material balance for the whole process showed that uranium and TRU could be recovered as products by 98.0 % and 97.0 %, respectively, from a PWR spent fuel while removing the other elemental groups into radioactive wastes. On the one hand, the TRU product was found to emit a considerable amount of ${\gamma}$-ray as well as neutrons favorably contributing to the strategy of proliferation resistance.

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Tracer Experiment for the Investigation of Urban Scale Dispersion of Air Pollutants - An Improved Method for the Release and Determination of Perfluorocarbon Tracers in the Urban Atmosphere (추적자 확산 실험에 의한 서울 도심 확산 현상 연구 - 도시규모 대기확산 실험을 위한 PFCs 추적자 방출 및 분석 시스템의 개발 및 적용 연구)

  • Yoo, Eun-Jin;Lee, Chong-Bum;Ro, Chul-Un;Kim, Hye-Kyeong;Lee, Gang-Woong
    • Journal of Korean Society for Atmospheric Environment
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    • v.23 no.5
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    • pp.547-556
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    • 2007
  • The release, sampling and analytical methods have been developed and tested for perfluorocarbons (PFCs) atmospheric tracers in order to gain insight into the atmospheric transport and dispersion over the urban conditions of Seoul, Korea. Although PFCs tracer experiments provide unique opportunities to test local and urban scale of transport and dispersion, no previous experiment with PFCs has been conducted in Korea. PMCH and PDCH were chosen as targeted tracers in our study due to their extreme low ambient concentrations and great sensitivities among various PFCs. For PFCs release system, a set of micro-metering pump, electronic balance, vaporizing furnace and high speed blower was constructed for precise and accurate release of tracers. The precision of released rate by this system was estimated to be 1%. Samplings of PFCs were carried out by fabricated portable air samplers with micro pumps and rotameters into glass tubes packed with 150 mg of Carboxen-569. The uncertainty of these sampling system was maintained below 14%. PMCH and PDCH were quantified in GC/ECD with preconditioned injection system to eliminate the interference compounds using traps and subsequent catalytic conversion system prior to column separation. Three intensive field test were undertaken during the springtime of 2002 to 2004 in eastern part of Seoul. Daily background samples were collected to characterize the background levels of PMCH and PDCH prior to their release. The observed background concentrations of PMCH ranged from 3.5 to 10.1 fL/L and varied randomly in location and time in this study. Its mean and standard variation of background concentration ($6.8{\pm}1.9\;fL/L$) are higher than those ($3.2{\sim}5.8\;fL/L$) of other historic tracer studies. Identified uncertainty for background PMCH was $1.7{\sim}2.0\;fL/L$ using this analytical system. Combined relative uncertainty in determining the tracer's concentrations was estimated as 17%. However, its background concentrations and uncertainty in concentration determination were found to be low and stable enough for tracer study.

Improvement of Atmospheric Dispersion Assessment for Accidental Releases Using a Fuzzy Logic Inference Method (퍼지 논리 추론 방법을 이용한 사고시 대기확산 평가 개선)

  • Na, Man-Gyun;Sim, Young-Rok;Kim, Soong-Pyung
    • Journal of Radiation Protection and Research
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    • v.26 no.1
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    • pp.19-26
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    • 2001
  • In order to assess the atmospheric dispersion for the accidental releases of nuclear power plants, in calculating X/Q values in the XOQAR and PAVAN codes which are based on Reg. Guide 1.145, the X/Q and frequency values are plotted on log-normal paper. Starting with the highest X/Q value of this plot, the codes compare the slope of the line drawn from this point to every other point within an increment containing ten X/Q values. If there are fewer than ten values, only the number available are used. The coefficients that produce the line with the least negative slope are saved. The end point of this line is used as the next starting point, from which slopes to the points within the next increment, containing ten X/Q values, are compared. The X/Q values corresponding to the cumulative frequency values 0.5%, 5% or 50% are calculated to search for the $0{\sim}2$ hour X/Q value that tends to be a very conservative value. In this work, a fuzzy logic inference method is used for nonlinear interpolation of the X/Q values versus the cumulative frequency. The fuzzy logic inference method is known to be a food technique for nonlinear interpolation. The proposed method was applied to a potential accidential radioactive release of the Yonggwang nuclear power plant, which gives more realistic X/Q values.

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