• Journal of the Korean Chemical Society
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• v.43 no.6
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• pp.676-681
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• 1999

Itraconazole is an important drug for oral treatment of histoplasmosis and blastomycosis. ltraconazole has been the targets of many synthetic efforts due to their diverse antifungal activities. ln this study, an efficient synthetic route for Itraconazole intermediates has been developed using new procedures. Also, ltraconazole analogues introducing 2- and 3-methoxy group instead of ltraconazole intermediates with 4-methoxy group were synthesized.

• Journal of the Korean Chemical Society
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• v.38 no.10
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• pp.763-768
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• 1994

As a part of synthetic programs aimed at Dolastatin 10 analogues, synthetic pathway toward various peptides were investigated. 4-Amino-3-hydr> Transfer interrupted!nalogues were prepared by ring opening of epoxides with ammonia in MeOH. Several peptides were prepared starting from these unusual amino acids through using mainly DCC coupling.

• Proceedings of the Membrane Society of Korea Conference
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• 1998.10a
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• pp.123-126
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• 1998

1960년 Allcock이 공기중에서 안정한 포스파젠고분자를 합성한 이래 포스파젠고분자는 열적, 화학적 안정성, 그리고 -P=N-골격에 다양한 측쇄를 부착함으로써 화학적으로 쉽게 고분자를 변형시킬 수 있다는 특징으로 인하여 이온교환막을 위한 기본고분자로 많은 관심을 끌고 있다. 1986년 MaCaffery등은 trifluoro- ethoxy를 치환한 고분자막을 합성하여 고온 안정성에 대한 특성을 실험한 바 있으며 1989년 Allen과 Macffrey등은 bistrifluoroethoxy를 치환시킨 포스파젠고분자를 합성하여 Co와 Mn이 들어있는 용액으로부터 Cr을 분리하였다. 그러나 trifluoroethoxy가 치환된 막은 소수성의 특징을 보이기 때문에 친수성이 요하는 곳에의 응용에는 사용할 수가 없었다. 친수성 포스파젠고분자의 합성의 경우는 1988년 Allcock과 Kwon등이 방사선을 이용하여 가교결합시켜 물에 녹지 않는 포스파젠 친수성 겔을 합성한 바 있으며 1990년 Wycisk등은 포스파젠 고분자를 슬폰화시켜 친수성을 가진 이온교환막을 합성하였다.

• Applied Chemistry for Engineering
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• v.33 no.4
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• pp.402-407
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• 2022

Statistical design of experiments was used to optimize the MOF-5 synthesis process. A mixture design was employed to optimize precursor concentration. The optimal composition of three chemical materials, terephthalic acid, zinc acetate dihydrate, and N,N-dimethylformamide for MOF-5 synthesis was determined by extreme vertices design methods as follows; 1 mol : 2.7 mol : 40 mol. A multilevel factorial design was selected to screen the significance of synthesis reaction conditions such as temperature, time, and stirring speed. Statistical analysis results suggested excluding stirring speed from further investigation. Using a central composition design, the synthesis time and temperature were optimized. The quadratic model equation was derived from 13 synthesis experiments. The model predicted that MOF-5 synthesized at 119 ℃ for 10.4 h had the highest crystallinity.

• Journal of the Korean Chemical Society
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• v.26 no.4
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• pp.256-260
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• 1982

• Journal of the Korean Chemical Society
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• v.59 no.6
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• pp.551-553
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• 2015

• The Science & Technology
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• v.30 no.5 s.336
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• pp.26-27
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• 1997

국내 최고의 첨단연구장비를 갖춘 이화여대 고체화학연구실은 6곳의 실험실에서 신소재 합성을 위해 저온에서부터 2천~3천도가 넘는 고온가열실험을 계속하고 있다. 이 연구소는 96년도 노벨상 수상 분야인 C60연구에 착수, C60을 합성하여 요오드를 도핑시킴으로써 I2C60을 만드는데 성공하여 미국 학술지에 소개되기도 했다.

• Journal of the Korean Chemical Society
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• v.52 no.4
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• pp.369-379
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• 2008

• Journal of the Korean Chemical Society
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• v.54 no.2
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• pp.181-182
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• 2010

• Journal of the Korean Chemical Society
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• v.39 no.11
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• pp.881-883
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• 1995