• Investigative Magnetic Resonance Imaging
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• v.16 no.2
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• pp.115-123
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• 2012

Purpose : To evaluate white matter abnormalities on diffusion tensor imaging (DTI) in patients with mild Alzheimer disease (AD) and mild cognitive impairment (MCI), using tract-based spatial statistics (TBSS) and voxel-based morphometry (VBM). Materials and Methods: DTI was performed in 21 patients with mild AD, in 13 with MCI and in 16 old healthy subjects. A fractional anisotropy (FA) map was generated for each participant and processed for voxel-based comparisons among the three groups using TBSS. For comparison, DTI data was processed using the VBM method, also. Results: TBSS showed that FA was significantly lower in the AD than in the old healthy group in the bilateral anterior and right posterior corona radiata, the posterior thalamic radiation, the right superior longitudinal fasciculus, the body of the corpus callosum, and the right precuneus gyrus. VBM identified additional areas of reduced FA, including both uncinates, the left parahippocampal white matter, and the right cingulum. There were no significant differences in FA between the AD and MCI groups, or between the MCI and old healthy groups. Conclusion: TBSS showed multifocal abnormalities in white matter integrity in patients with AD compared with old healthy group. VBM could detect more white matter lesions than TBSS, but with increased artifacts.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.6
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• pp.1363-1368
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• 2011

This paper describes an analysis on the granular noise in pixel-to-pixel mapping-based computational integral imaging. The pixel mapping-based method provides a high-resolution reconstructed images and also its computational cost is very lower than the previous back-projection-based method. In this paper, a signal model for the pixel mapping-based method is introduced, which defines and analyzes the granular noise. Computer experiments provides the granular noise properties based on the proposed signal model. The experimental results indicates that the granular noise pattern differs from that of the back-projection based method. The results is also utilized in the pixel mapping-based method.

• Korean Journal of Biological Psychiatry
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• v.16 no.3
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• pp.190-197
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• 2009

Objectives : The purpose of this study was to examine structural abnormalities of brain in patients with pathological gambling(PG) using voxel-based morphometry. Methods : We compared gray matter(GM) volumes between 10 patients with PG and 14 age- and IQ-matched healthy controls and examined the relationship of GM volumes with clinical variables in patients with PG. Results : We found significant increase of GM volume in the superior, middle, and inferior frontal gyri, the midbrain, the middle temporal gyrus, the precuneus, and the fusiform gyrus of patients with PG. A significant decrease of GM volume was observed in the parahippocampal gyrus and the lingual gyrus of the patient group. In addition, GM volumes in some of these regions were positively associated with South Oaks Gambling Screen score and negatively with age of onset in patients with PG. Conclusion : Current findings indicate that structural abnormalities in the fronto-temporal cortex, the midbrain, and the precuneus might be involved in the pathophysiology of PG, and contribute to some of the behavioral changes observed in patients with PG.

• Journal of Intelligence and Information Systems
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• v.8 no.1
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• pp.75-85
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• 2002

In this paper, we propose an efficient method for recognizing lip. Lip is localized by using the shape of lip and the pixel values around lip contour. The shape of lip is represented by a statistically based active shape model which learns typical lip shape from a training set. Because this model is affected by the initial position, we use a boundary between upper and lower lip as initial position for searching lip. The boundary is localized by using a weighted vector based on lip's shape. The experiments have been performed for many images, and show very encouraging result.

• Korean Journal of Biological Psychiatry
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• v.15 no.2
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• pp.118-125
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• 2008

Objectives : The purpose of this study was to find brain regions in which gray matter volume was reduced and to show the capability of voxel-based morphpmetry(VBM) analysis for lateralizing clinically significant brain regions in dementia of Alzheimer's type patients compared to healthy group. Methods : MR T1-weighted images of the 20 dementia of Alzheimer's type patients were compared with those of the 20 normal controls. Images were transformed to standard MNI space. In order to observe gray matter volume change. Gray matter was smoothed with a Gaussian kernel. After these preprocessing, statistical analysis was performed using statistical parametric mapping software(SPM2). Results : Gray matter volume was significantly reduced in the bilateral parahippocampal gyri, Lt. anterior cingulate gyrus, Lt. posterior cingulate gyrus, bilateral superior temporal gyri Lt. middle temporal gyrus, Lt. superior, bilateral middle, Rt. anterior frontal gyri and Rt. precuneus in dementia of Alzheimer's type patient group. Conclusions : These VBM results confirm previous findings of temporal lobe and limbic lobe atrophic changes in dementia of Alzheimer's type, and suggest that these abnormalities may be confined to specific sites within that lobe, rather than showing a widespread distribution.

• The Journal of the Korea Contents Association
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• v.16 no.7
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• pp.31-41
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• 2016

Atmospheric correction as a preprocessing work should be performed to conduct accurately landcover/landuse classification using hyperspectral imagery. Atmospheric correction on airborne hyperspectral images was conducted and then the effect of atmospheric correction by comparing spectral reflectance characteristics before and after atmospheric correction for a few landuse classes was analyzed. In addition, land cover classification was first conducted respectively by the maximum likelihood method and the spectral angle mapper method after atmospheric correction and then the results were compared. Applying the spectral angle mapper method, the sea water area were able to be classified with the minimum of noise at the threshold angle of 4 arc degree. It is considered that object-based classification method, which take into account of scale, spectral information, shape, texture and so forth comprehensively, is more advantageous than pixel-based classification methods in conducting landcover classification of the coastal area with hyperspectral images in which even the same object represents various spectral characteristics.

• Korean Journal of Biological Psychiatry
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• v.18 no.4
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• pp.232-238
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• 2011

Objectives Optimized voxel based morphometry (VBM) has been increasingly applied to investigate differences in the brain morphology between a group of patients with mild cognitive impairment (MCI) and control subjects. Optimized VBM permits comparison of gray matter (GM) volume at voxel-level from the entire brain. The purpose of this study was to assess the regional GM volume change measured by optimized VBM in MCI subjects compared to controls. Methods Twenty patients with MCI and 20 control subjects with normal cognition were recruited for this study. We applied the optimized VBM protocol to the image data including study-specific template and the modulation of the data with the Jacobian determinants. GM volume differences between the MCI subjects and the control subjects and their correlations with the neuropsychological performances were investigated. Results Optimized VBM analysis revealed GM volume reduction in hippocampus, precentral gyrus, insula and parietal operculum in the MCI group compared to the control group (family wise error corrected p < 0.05). Korean version of the Consortium to Establish a Registry for Alzheimer's disease (CERAD-K) word list recall scores were significantly correlated with the GM volumes of hippocampus, precuneus and posterior cingulate in the MCI group (FWE corrected p < 0.05). Conclusions The results confirm previous findings of atrophic changes in medial temporal lobe and parietal lobe in the MCI group and suggest that these abnormalities may be related with cognitive decline and prognosis in patients with MCI.

• Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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• 2004.03a
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• pp.273-278
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• 2004

Feature identification is one of the largest issue in high spatial resolution satellite imagery. A popular method associated with this feature identification is image segmentation to produce image segments that are more likely to features interested. Here, it is, proposed that combination of edge extraction and region growing methods for image segments were used to improve the result of image segmentation. At the intial step, an image was segmented by edge detection method. The segments were assigned IDs, and polygon topology of segments were built. Based on the topology, the segments were tested their similarities with adjacent segments using multivariate analysis. The segments that have similar spectral characteristics were merged into a region. The test application shows that the segments composed of individual large, spectrally homogeneous structures, such as buildings and roads, were merged into more similar shape of structures.

• Proceedings of the KSRS Conference
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• 2006.03a
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• pp.307-310
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• 2006

고해상도(VHR, Very High Resolution) 영상은 활용에 따라 도심의 다양한 정보를 얻을 수 있는 잠재적 가치가 매우 큰 자료이다. 그러나 이러한 고해상도 영상자료는 매우 높은 공간해상력으로 인해 같은 용도의 객체 혹은 같은 객체(예, 건물)라 할지라도 다양한 분광 특성 및 형태로 표현된다. 그러므로 이러한 고해상도영상을 이용하여 효과적으로 주제도를 생성하기 위해서는 현재까지 영상분류 분야에서 주로 활용되고 있는 화소(pixel)단위 기반의 분석방법으로는 한계가 존재한다. 본 연구에서는 이러한 문제점을 보완하기 위한 방법으로 활발한 연구가 진행되고 있는 세그멘트(segment) 혹은 객체(object) 기반 분류기법을 고해상도 영상 및 라이다 자료에 적용하여 도심지역의 건물들을 추출해 보았으며, 그 활용 가능성에 대하여 판단해 보았다. 이러한 세그멘트 기법은 분류하고자 하는 객체들을 하나의 동일한 특성을 가지는 집단으로 모으는 방법을 말하는데, 이를 위해 본 연구에서는 multi-resolution image segmentation기법을 제공해주는 eCognition이라는 소프트웨어를 이용하였다.

• Journal of the Korean association of regional geographers
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• v.23 no.1
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• pp.136-150
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• 2017

This study analyzed the spatial change of urban green spaces in Daegu from 1989 to 2009 using cell based spatial metrics. To do so, the conversion process of land covers during the past 20 years was explored using a land cover change detection matrix. The synoptic analysis with a moving window sampling strategy was conducted to quantify cell based spatial metrics related to size, shape, cohesion, and diversity and to explain the spatial change at the local level. Difference maps were then generated by subtracting the 1989 maps of spatial metrics from the 1998 maps and the 1998 maps from the 2009 maps. The gradient analysis was performed to identify the directional change of spatial metrics along an urban development axis in Daegu. The results from this study show that urban green spaces in Daegu during the past 20 years have been gradually fragmented around the new town housing development districts such as Dalseong-gun, Seongseo, and Ansim. Forests were most prominently fragmented in the Hwawon area while most rapidly in the Chilgok area. Grasslands were largely fragmented in many areas due to the decrease in size and cohesion indices and most fragmented in the Ansim area. The spatial pattern of the decreased and fragmented urban green spaces identified by this study can be used as a base data for establishing the environment-friendly urban development strategy in Daegu.