• Korean Journal of Clinical Laboratory Science
• /
• v.53 no.4
• /
• pp.285-295
• /
• 2021

Sleep plays an important role in maintaining overall human health. There is increasing interest regarding the impact of sleep related disorders on metabolic diseases. Obstructive sleep apnea (OSA) is a common health problem, and in the last decade, the emergence of increasing obesity rates has further led to a remarkable increase in the prevalence of OSA, along with more prominent metabolic diseases. Obesity is the strongest risk factor for OSA. However, OSA is also known to cause obesity, suggesting an interaction between OSA and obesity. Although the underlying mechanisms leading to OSA-induced metabolic diseases are probably multi-factorial and are yet to be fully elucidated, the activation of inflammation and oxidative stress and the dysregulation of appetite-regulating hormones have emerged as important pathophysiological components of metabolic dysfunction and obesity observed in patients with OSA. Here, we will review the current state of research regarding the association of OSA with metabolic diseases and the possible pathophysiological mechanisms by which OSA could lead to such diseases. This will enhance our understanding of the potential interactions between OSA and obesity and between OSA and metabolic dysfunction.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2003.05a
• /
• pp.514-517
• /
• 2003

Oxygen supply is one of the most basic things in human body. Breathing is controlled by the lungs' stationary function and the respiratory center which is in the mesulla oblongata. Nothing but, the external breathing that air movement between the lungs and atmosphere and the internal breathing that cellular air movement between the hemoglobin and a single cell. The adult's number of times of the respirations is about 15∼20 per 1 minute, but it depends ages, exercise, temperature, disease, etc. The important thing in detecting the respiration is that doing it in object person's resting time. Detecting the respiration have to be done without attracting any attention of object person. In present using method is detecting the pulse with catching an object person's wrist and observing the object person's movement. In this paper, we propose the mobile respiration detection diagnostic system using ultrasound sensing method that does not be influenced by the inertia error and the pressure error.

• Journal of Oral Medicine and Pain
• /
• v.37 no.4
• /
• pp.213-219
• /
• 2012

Oral appliances are a primary treatment option for snoring and mild to moderate obstructive sleep apnea (OSA) and are considered as an alternative for patients with severe OSA who have failed continuous positive airway pressure (CPAP) or upper airway surgery. But it is true that OAs have varying degrees of effectiveness depending on different oral appliances and the efficacy of OAs are established in some but not all patients. New oral appliance, which is one of Adjustable Anterior Positioners, was developed by Dept of Oral Medicine, Dental School, Dankook University. This is a report for treating severe OSA patient with a failure of previous uvulopalatopharyngoplasty using a new Adjustable Anterior Positioner, followed by significant success of controlling OSA.

• Journal of Yeungnam Medical Science
• /
• v.1 no.1
• /
• pp.95-100
• /
• 1984

In the beginning of anesthetic training, one of the clinical practices that anesthetists have to learn is manually controlled ventilatory techniques. The popularity of manually controlled ventilatory techniques has been gradually decreased with increased use for anesthetic ventilators. However it is important and basic for the anesthetists to master manually controlled ventilatory techniques skillfully. Recently, we analyzed the arterial blood gas in 30 cases before and during general anesthesia, and studied the effects of the manually controlled ventilation on the pulmonary gas exchange. The results were as follow; 1) Mean value of $PaCO_2$ during the manually controlled ventilation, $29.9{\pm}2.9mmHg$ was decreased statistically comparing with that of $PaCO_2$ before the anesthesia, $39.8{\pm}2.8mmHg$. 2) Mean values of pH and ${HCO_3}^-$ during the manually controlled ventilation were $7.48{\pm}0.03$, $22.2{\pm}2.4mEq/l$, respectively and values before the anesthesia were $7.41{\pm}0.02$, $25.2{\pm}1.8mEq/l$, respectively. 3) Mean values of $PaO_2$ and $O_2$ saturation during the manually controlled ventilation were $270.0{\pm}28.8mmHg$, $99.6{\pm}0.2%$, respectively and values before the anesthesia were $92.5{\pm}4.0mmHg$, $96.9{\pm}1.0%$ respectively. These results indicates that manually controlled ventilation at our department of anesthesiology produced mild hyperventilatory state. However these were no significant changes in cerebral blood flow and other biochemical parameters.

• Tuberculosis and Respiratory Diseases
• /
• v.46 no.6
• /
• pp.803-810
• /
• 1999

Background : The patient's work of breathing(WOBp) during assisted ventilation may vary according to many factors including ventilatory demand of the patients and applied ventilatory setting by the physician. Pressure-controlled ventilation(PCV) which delivers gas with decelerating flow may better meet patients' demand to improve patient-ventilator synchrony compared with volume-controlled ventilation(VCV) with constant flow. This study was conducted to compare the difference in WOBp in two assisted modes of ventilation, PCV and VCV with constant flow. Methods : Ten patients with respiratory failure were included in this study. Initially, the patients were placed on VCV with constant flow at low tidal volume($V_{T,\;LOW}$)(6-8 ml/kg) or high tidal volume($V_{T,\;HIGH}$)(10-12 ml/kg). After a 15 minute stabilization period, VCV with constant flow was switched to PCV and pressure was adjusted to maintain the same tidal volume($V_T$) received on VCV. Other ventilator settings were kept constant. Before changing the ventilatory mode, WOBp, $V_T$, minute ventilation($V_E$), respiratory rate(RR), peak airway pressure (Ppeak), peak inspiratory flow rate(PIFR) and pressure-time product(PTP) were measured. Results : The mean $V_E$ and RR were not different between PCV and VCV during the study period. The Ppeak was significantly lower in PCV than in VCV during $V_{T,\;HIGH}$. HIGH ventilation(p<0.05). PIFR was significantly higher in PCV than in VCV at both $V_T$ (p<0.05). During $V_{T,\;LOW}$ ventilation, WOBp and PTP in PCV($0.80{\pm}0.37\;J/min$, $164.5{\pm}74.4\;cmH_2O.S$) were significantly lower than in VCV($1.06{\pm}0.39J/mm$, $256.4{\pm}107.5\;cmH_2O.S$)(p<0.05). During $V_{T,\;HIGH}$ ventilation, WOBp and PTP in PCV($0.33{\pm}0.14\;J/min$, $65.7{\pm}26.3\;cmH_2O.S$) were also significantly lower than in VCV($0.40{\pm}0.14\;J/min$, $83.4{\pm}35.1\;cmH_2O.S$)(p<0.05). Conclusion : During assisted ventilation, PCV with decelerating flow was more effective in reducing WOBp than VCV with constant flow. But since individual variability was shown, further studies are needed to confirm these results.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.12 no.4
• /
• pp.264-276
• /
• 2010

The objectives of this study were to introduce the methods of soil respiration measurement, to review soil respiration studies conducted in Korea, and to suggest potential issues generated from using various methods for soil respiration measurement. According to the measurement principles, the methods of soil respiration measurements are classified as: alkali absorption method (AA), closed chamber method (CC), closed dynamic chamber method (CDC), and open flow method (OF). Based on the litereaure review on soil respiration studies in Korea, the CDC method was mostly used by the researchers (62%), followed by the AA (17%), OF (13%) and CC (8%) methods. Along with these methods, various instruments were used such as LI-6400-09, EGM-3, EGM-4, and automatic soil respiration chamber. Most of the soil respiration measurements were carried out in forest ecosystems and the reported soil respiration showed a wide range of variations from 130 to 900 mg $CO_2\;m^{-2}h^{-1}$. Continuous monitoring of soil respiration with minimal disturbance and the potential inconsistency in measurements are still the challenges facing the researchers, causing a paucity in quality datasets of sufficient quantity. Few attempts of intercomparison among different methods hinder the data users from synthetic analysis and assessment of the collected datasets. In order to better estimate soil carbon budget and understand their exchange mechanisms in key ecosystems of Korea, it is necessary to measure soil respiration at various plant functional types, soils, and climate conditions over a decadal time scale along with the study on the partitioning of soil respiration into autotrophic and heteorotrophic components.

• Proceedings of the KSLP Conference
• /
• 1998.11a
• /
• pp.180-180
• /
• 1998

목소리를 많이 사용하는 사람들에서 발생되는 음성장애는 대부분 잘못된 발성방법으로 인한 후두의 과긴장으로 인해 야기되는 것으로, 흡기 및 호기를 자발적으로 조절할 수 있는 호흡방법과 성대 및 주변 근육의 긴장을 줄이도록 하는 훈련하는 음성치료가 주된 치료 방법으로 대두되고 있다. 지금까지 음성치료의 효과는 주로 청음인지적(perceptual) 측면에서 많이 논의되어 왔으며 객관적인 자료는 아직까지 별로 없는 상태이다. 더욱이 호흡 및 발성 방법에 따른 음성 분석은 미진한 상황이다. (중략)

• Journal of the Korean Applied Science and Technology
• /
• v.34 no.4
• /
• pp.1104-1111
• /
• 2017

In this study, the authors aimed to give careful consideration to the circulation of bioenergy (Qi) by using cardiorespiratory massage technique. Finding enlightenment in harmony with nature thousands of years ago, our ancestors created Qi using natural breathing and tried to achieve good health and long life by controling the up and down movement. Experiencing the importance of the abdomen during the hungry times, also, grandmothers cured diseases by rubbing the abdomen, which is the ocean of life with their soft, soothing touch of hand. Naval breathing therapy was formed, based on natural breathing, emotional recognition of grandmothers' soft, soothing touch, and the Theory of Unified Reason and Energy that is the key of Oriental medicine. Natural breathing and Yakson massage are kinds of naturopathy to change body and mind, cure diseases naturally, and maintain the improvement in physical functions by taking care of the abdomen through the creation of Qi and the up and down movement and keeping dynamic balance between the natural world and the inside and outside of human body. It is anticipated that this study could contribute to the practical spread for an active application of naval breathing therapy and be broadly used in scientific clinical researches.

• Progress in Medical Physics
• /
• v.25 no.4
• /
• pp.242-247
• /
• 2014

To see the discrepancies between the calculated and the delivered dose distribution of IMRT fields for respiratory-induced moving target according to the motion ranges. Four IMRT plans in which there are five fields, for lung and liver patients were selected. The gantry angles were set to $0^{\circ}$ for every field and recalculated using TPS (Eclipse Ver 8.1, Varian Medical Systems, Inc., USA). The ion-chamber array detector (MatriXX, IBA Dosimetry, Germany) was placed on the respiratory simulating platform and made it to move with ranges of 1, 2, and 3 cm, respectively. The IMRT fields were delivered to the detector with 30~70% gating windows. The comparison was performed by gamma index with tolerance of 3 mm and 3%. The average pass rate was 98.63% when there's no motion. When 1.0, 2.0, 3.0 cm motion ranges were simulated, the average pass rate were 98.59%, 97.82%, and 95.84%, respectively. Therefore, ITV margin should be increased or gating windows should be decreased for targets with large motion ranges.

• The Science & Technology
• /
• v.34 no.1 s.380
• /
• pp.92-93
• /
• 2001

혈압과 호흡 등 생명활동을 조절하고 인체균형을 유지하며 호르몬 분비를 총괄하고 기억ㆍ사고ㆍ판단 및 감정 등 모든 활동을 담당하는 뇌. 이 책은 신비로운 뇌의 세계를 소상하게 풀어주고 있다.