• Clinical and Experimental Pediatrics
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• v.46 no.12
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• pp.1200-1206
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• 2003

Purpose : This study was conducted for the use of nasal continuous positive airway pressure (CPAP), by comparing the early use of non-invasive nasal CPAP with low intermittent mandatory ventilation(low IMV) and endotracheal CPAP in weaning a mechanical ventilator from infants with moderate respiratory distress syndrome(RDS). Methods : Thirty infants in the study group, with moderate RDS from November 2001 to June 2002, were administered surfactants and treated with the mechanical ventilator, and applied the nasal CPAP in weaning. Thirty infants of the control group, from January 1999 to September 2001, were applied low IMV and endoctracheal CPAP in weaning. Results : There were no significant differences in the characteristics, the severity of clinical symptoms, the initial laboratory findings and settings of the mechanical ventilator. After weaning, the study group showed no significant changes in $PaCO_2$. However, the control group showed a slight $CO_2$ retension after one and 12 hours. Twenty eight infants(93.3%) of the study group and 24 infants(80%) of the control group were successfully extubated. The primary cause of failure was apnea. There were no significant differences in the duration of weaning and the mechanical ventilator treatment between the groups. Complications in weaning were related to the fixation of nasal CPAP and the mechanical problems caused by endotracheal tube. Conclusion : Aggressive weaning is possible for moderate RDS, in which the nasal CPAP was used without the low IMV and the endotracheal CPAP process. It had no difficulties. In conclusion, the nasal CPAP is an adequate weaning method for moderate RDS.

• Feed Journal
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• v.2 no.9
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• pp.108-111
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• 2004

어느 농장이건 정도 차이만 있을 뿐, 호흡기 질병은 누구나 고민거리 이자 해결 하기가 만만치 않을 것이다. 더구나 계절적 온.습도차나 밤낮의 일교차가 큰 우리나라는 자연환경의 변화에 사람 살기는 좋을지 몰라도 돼지를 키우기에는 취약한 점이 너무 많은 편이다. 더러는 무항생제 사육도 강조되고 어쨌든 항생제 규제가 강해질 것은 자명한데 열악한 시설과 환경속에서는 속수무책이 될수도 있다. (중략)

• Tuberculosis and Respiratory Diseases
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• v.61 no.2
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• pp.114-120
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• 2006

• 건강소식
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• v.30 no.12 s.337
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• pp.14-15
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• 2006

겨울철이 되면 추위를 피해 따뜻한 실내에서 생활하는 시간이 많아지므로 자연히 실외활동이 현저하게 줄어든다. 사람들이 실내로 모여들기 때문에 밀폐된 공간에는 미세한 먼지나 각종 오염물질로 넘쳐난다. 이것은 호흡기 질환에 쉽게 노출되어 있다는 것을 말한다. 하지만 우리의 몸은 뛰어난 적응력을 자랑하므로 규칙적인 운동과 충분한 휴식, 철저한 위생관리와 적절한 영양섭취를 통해 겨울철 질병에서 자유롭게 벗어날 수 있다.

• 건강소식
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• v.36 no.10
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• pp.28-29
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• 2012

일교차가 10도 이상 나는 날씨가 계속되면 우리 몸의 생체리듬이 혼란을 겪게 된다. 공기를 마시고 내뱉는 호흡기는 이 같은 기온 변화에 굉장히 민감해 환절기에는 감기 등 호흡기 질환에 걸리기 쉽기 때문에 특별히 건강관리에 주의를 기울여야 한다. 특히 감기와 독감은 증상이 비슷하지만 원인이 되는 바이러스는 전혀 다르므로 치료방법이나 그 대응도 달라야한다.

• Feed Journal
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• v.3 no.9 s.25
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• pp.136-141
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• 2005

환절기나 겨울철에 사람들은 독감, 천식, 비염 등 호흡기성 질환의 발병율이 높아지는 것과 동일하게 닭에서도 호흡기성 질병이 발생된다. 더군다나 닭은 어느 동물보다 호흡기를 구성하고 있는 실질장기들의 표면적이 넓어 그 만큼 많은 병원체에 쉽게 감염되며, 이에 따라 양계농장에서는 이들 전염병으로 피해가 속출하고 있다. 밤낮 기온차가 큰 환절기나 추운 겨울철에는 계사내 보온과 에너지절약, 이 두 가지 효과를 동시에 얻기 위해 노력하다 보면 신선한 산소의 제공

• Clinical and Experimental Pediatrics
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• v.51 no.11
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• pp.1179-1184
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• 2008

Purpose : Pulmonary interstitial emphysema (PIE) primarily occurs in preterm infants suffering from respiratory distress syndrome (RDS) and kept under mechanical ventilator care. Therefore, this study aimed to examine various risk factors for PIE, to identify conditions that can decrease the possibility of PIE development. Methods : PIE classification was conducted for 183 patients diagnosed to have RDS and receiving mechanical ventilator care with pulmonary surfactant between March 2000 and February 2007. The characteristics of each patient were analyzed through retrospective examination of their medical histories. Results : Among 183 patients, 17 had PIE; all factors, including birth weight, gestational age, RDS grade III or above, chorioamnionitis, and premature rupture of membranes, were statistically significant (P<0.05). The period of mechanical ventilator use was statistically significant, but the peak mean airway pressure and peak partial pressure of inspired oxygen were not. PIE mainly occurred on the right side or both sides rather than the left side and mostly developed within 72 h. The PIE group showed higher mortality rate than the control group, and the major cause of mortality was pneumothorax. Conclusion : Risk factors for PIE in infants suffering from RDS and kept under mechanical ventilator care include low gestational age, low birth weight, chorioamnionitis, and premature rupture of membranes. If any risk factors are noted, the infant must be observed closely for at least 72 h after birth.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.241-249
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• 2017

This study was to determine the effectiveness of oral decontamination with chlorhexidine for prevention of ventilator associated pneumonia(VAP) using meta-analysis. MEDLINE, Pubmed, Cochrane library CINAHL and RISS, Koreamed, KISS databases were searched. key words used 'Ventilator-associated pneumonia', 'oral care', 'chlorhexidine' Ninety studies met the inclusion criteria for the meta-analysis. data were analyzed by the Revman 5.3 program of cochrane library and assessed for methodological quality using RoB (The Cochrane's Risk of Bias). The main findings of the current study suggest that chlorhexidine oral care have a positive impact on Ventilator associated pneumonia.

• Fire Science and Engineering
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• v.21 no.2 s.66
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• pp.64-73
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• 2007

The absorption characteristics of hazardous materials onto human body and defense mechanism differ from each other region within the respiratory tracts, thus adverse health effects of inhaled smokes are associated with not only the concentration but also the location of the particles deposited. In this work, the deposition fraction per surface area and the deposition sites of the smoke particles in human respiratory tracts for each rest and light exercise conditions together with oral and nasal breathing were calculated by using segmental volume tracking method. The results would be used for deriving the amount of absorption of hazardous materials onto human body, thus contribute to the health risk assessments of inhaled fire smokes.

• Particle and aerosol research
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• v.20 no.3
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• pp.79-94
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• 2024

Exposure to ambient particulate matter (PM) 2.5 can impair alveolar macrophages (AMs) functions and induce pathological conditions. This study explores the impact of PM2.5 exposure on AMs, focusing on gene expression changes and functional alterations. Murine AMs cell line MH-S were exposed to PM2.5 at a concentration of 100 ㎍/ml for durations of 3 and 48 hours. After 3 hours of exposure, genes involved in inflammatory and immune responses were activated, including TNF and B-cell receptor signaling pathways. In contrast, 48 hours of exposure significantly altered genes related to cell proliferation, apoptosis, and immune processes, with PI3K-Akt and cytokine-cytokine receptor interaction pathways. PM2.5 initially triggers immune responses; however, prolonged exposure over 48 hours impairs AM functions risk of chronic inflammation and cancer. This research provides foundational data for therapeutic approaches related to PM2.5 exposure.