• Title/Summary/Keyword: 형태적 손상

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Influence of Starvation on the Variations of Hepatocyte Nucleus in Larvae of Red Spotted Gruper, Epinephelus akaara (기아시 붉바리 자어의 간세포핵 변화)

  • 이창규;박인석;허성범
    • Journal of Aquaculture
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    • v.11 no.1
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    • pp.11-17
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    • 1998
  • Variations of hepatocyte in the larval liver of grouper, Epinephelus akaara wre examined to understand the effect of starvation during the first feeding period, 3 to 5 days after hatching. Total length of the fed larvae increased from the 5th day after hatching, although no significant difference between the fed and starved larvae was found untill the 4th day after hatching. Survival rate of the starved larvae decreased from the 4th day after hatching, and almost all of the larvae died by the 5th day after hatching. Nuclear size of hepatocyte in the starved larvae starterd to decrease from the 4th day after hatching. The sizes by 4th and 5th days after hatching in the starved larvae were 1.4 to 1.9 times smaller than those in the fed ones. Hepatocytes in the starved larvae showed irregular morphology in which the nuclei were irregularly shrunk and highly compacted from the 4th day, while hepatocyte nuclei in the fed ones maintained their uniform features during the whole experimental period. These results implied that the initial larval food should be supplied at least within the 4th day after hatching. Also, it suggested that the size of hepatocyte nucleus might be and indicator of starvation for wild and cultured grouper larvae.

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Skin Damage Sustained During Head-and-Neck and Shoulder Radiotherapy Due to the Curvature of Skin and the Use of Immobilization Mask (머리-목 그리고 어깨의 방사선 치료 시 피부곡면과 고정장치로 인한 피부손상연구)

  • Kim, Soo-Kil;Jeung, Tae-Sig;Lim, Sang-Wook;Park, Yeong-Mouk;Park, Dahl
    • Progress in Medical Physics
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    • v.21 no.1
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    • pp.86-92
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    • 2010
  • The purpose of this study was to measure curvature contour skin dose using radiochromic film and TLD for a conventional open field. We also attempted to quantify the degradation of skin sparing associated with use of immobilization devices for high energy photon beams and to calculate the skin dose with a help of Monte Carlo (MC) simulation. To simulate head-and-neck and shoulder treatment, a cylindrical solid water phantom 11 cm in diameter was irradiated with 6 MV x-rays using $40{\times}40\;cm^2$ field at 100 cm source axis distance (SAD) to the center of the phantom. Aquaplastic mesh mask was placed on the surface of the cylindrical phantom that mimicked relevant clinical situations. The skin dose profile was obtained by taking measurements from $0^{\circ}$ to $360^{\circ}$ around the circumference of the cylindrical phantom. The skin doses obtained from radiochromic film were found to be 47% of the maximum dose of $D_{max}$ at the $0^{\circ}$ beam entry position and 61% at the $90^{\circ}$ oblique beam position without the mask. Using the mask (1.5 mm), the skin dose received was 59% at $0^{\circ}$ incidence and 78% at $80^{\circ}$ incidence. Skin dose results were also gathered using thin thermoluminescent dosimeters (TLD). With the mask, the skin dose was 66% at $0^{\circ}$ incidence and 80% at $80^{\circ}$ incidence. This method with the mask revealed the similar pattern as film measurement. For the treatments of the head-and-neck and shoulder regions in which immobilization mask was used, skin doses at around tangential angle were nearly the same as the prescription dose. When a sloping skin contour is encountered, skin doses may be abated using thinner and more perforated immoblization devices which should still maintain immoblization.

An Implementation of Brain-wave DB building system for Artifacts prevention using Face Tracking (얼굴 추적 기반의 잡파 혼입 방지가 가능한 뇌파 DB구축 시스템 구현)

  • Shin, Jeong-Hoon;Kwon, Hyeong-Oh
    • Journal of the Institute of Convergence Signal Processing
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    • v.10 no.1
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    • pp.40-48
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    • 2009
  • Leading of the computer, IT technology has make great strides. As a information-industry-community was highly developed, user's needs to convenience about intelligence and humanization of interface is being increase today. Nowadays, researches with are related to BCI are progress put the application-technology development first in importance eliminating research about fountainhead technology with DB construction. These problems are due to a BCI-related research studies have not overcome the initial level, and not toward a systematic study. Brain wave are collected from subjects is a signal that the signal is appropriate and necessary in the experiment is difficult to distinguish. In addition, brain wave that it's not necessary to collect the experiment, serious eyes flicker, facial and body movements of an EMG and electrodes attached to the state, noise, vibration, etc. It is hard to collect accurate brain wave was caused by mixing disturbance wave in experiment on the environment. This movement, and the experiment of subject impact on the environment due to the mixing disturbance wave can cause that lowering cognitive and decline of efficiency when embodied BCI system. Therefore, in this paper, we propose an accurate and efficient brain-wave DB building system that more exactness and cognitive basis studies when embodied BCI system with brain-wave. For the minimize about brain wave DB with mixing disturbance, we propose a DB building method using an automatic control and prevent unnecessary action, put to use the subjects face tracking.

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Induction of Apoptosis by Vitamin E Succinate in Human Erythroleukemia K562 Cells (인간 만성백혈병 세포주에서의 Vitamin E Succinate에 의한 세포사멸 유도)

  • Jang, Chang-Deug;Kim, Jong-Myoung;An, Won-Geun;Park, Hye-Ryoun
    • Journal of Life Science
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    • v.17 no.7 s.87
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    • pp.896-904
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    • 2007
  • Regulation mechanism of apoptosis has been known to be important for understanding the pathogenesis of a number of human diseases including cancers. The effects of $RRR-{\alpha}-tocopheryl$ succinate(vitamin E succinate, VES) on the cell viability, generation of ROS, expression of proteins involved in apoptosis, and growth of human chronic myelogenous leukemia K562 cells were analyzed in this study. VES treatment not only induced the generation of the ROS but also increased the levels of $NF-{\kappa}B$, COX-2, and $p21^{WAF1/CIP1}$ in K562 cells. It modulates the levels of pro-apoptotic proteins such as Bax provoking the apoptosis in K562 cells. The cleavage of PARP into 89 kDa was also increased upon VES treatment in a dosage-dependent manner. Induction of an apoptosis was evident by the increase of sub-Gl peak and cell shrinkage condensed chromatin in K562 cells treated with VES. It also resulted in an inhibition of tumor growth by 50% and prolonged survival of the Iymphoma-induced mice. This potentiation of VES obtained in vitro and in vivo may indicate the feasibility of more effective chemotherapy in chronic myelogenous leukemia.

Application Study of Dry-ice Pellet Cleaning for Removing Oil Paint and Lacquer of Outdoor Metal Artifacts (Dry-ice Pellet Cleaning 적용 옥외 금속문화재 표면 페인트 및 유성물질 제거방법 비교 연구)

  • Lee, Jee-Eun;Cho, Nam-Chul;Lee, Jong-Myoung;Yu, Jae-Eun
    • Journal of Conservation Science
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    • v.28 no.3
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    • pp.217-228
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    • 2012
  • Damage of cultural properties happens variously. Particularly, the surface damage of metal cultural properties exposed outdoors lowers historical and art historical value of artifact by artificial damage such as paint, scribbling containing oily material and so on. Therefore, this study compared dry-ice pellet cleaning with poultice when clearing paint and oily material environment-friendly, harmlessly to humans and without damage of artifact. As the result of experiment, when clearing those (paint and oily material) by poultice, oily paint was cleared, but there were spots of metal surface. Also, Lacquer spray wasn't well cleared, and resin came off the surface of artifact. When clearing those by dry-ice pellet cleaning, oil paint was cleanly cleared without surface damage of artifact according to Stereoscopic microscope observation, color-measurement, FT-IR, SEM analysis. Also, lacquer spray seemed to be cleared with the naked eye, but there were minute particles on surface according to the result of SEM observation. Consequently, we could confirm possibility of dry-ice pellet cleaning substitution.

Flexural Behavior of Reinforced Concrete Beams Retrofitted with Modified Polymer Mortar System (폴리머 모르타르로 단면을 복구한 철근콘크리트 보의 휨 거동)

  • Hong Geon-Ho;Choi Eun-Gyu;Lee Su-Jin;Shin Yeong-Soo
    • Journal of the Korea Concrete Institute
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    • v.16 no.1 s.79
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    • pp.94-101
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    • 2004
  • This study shows the test results of seven RC beams retrofitted with modified polymer system and parametric study about the effects of tensile strength of retrofitting materials by analytical method on the flexural behavior. The main parameters are the retrofitted depth and length. The beams are loaded to the failure by four-point loading. Test results show that the effect of the retrofitted length on the structural behavior is more significant than that of depth. As the retrofitted depth is increased, the beams represents the brittle failure mode The non-linear analysis is carried out to grasp the effect of the tensile strength of retrofitting material on the structural behavior. As the retrofitted depth and length are increased, the tensile strength becomes more effective so these parameters should be considered to determine the retrofitted area. The analytical results show that failure strength is less than that of experimental results, but the stiffness is vice versa.

Exchange coupling field of NiFe/IrMn/CoFe trilayer depending on Mn composition (3중박막 NiFe/IrMn/CoFe에서 Mn 함유량에 의존하는 교환결합세기)

  • 김보경;이진용;함상희;김순섭;이상석;황도근;김선욱;이장로
    • Proceedings of the Korean Magnestics Society Conference
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    • 2003.06a
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    • pp.130-131
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    • 2003
  • The magnetic and thermal properties of NiFe/IrMn/CoFe with Mn additions have been studied. As grown CoFe pinned-layers with IrMn-Mn have dominantly larger exchange biasing field( $H_{ex}$) and blocking temperature( $T_{b}$) than when pure I $r_{22}$M $n_{78}$ is used. The magnetic properties improve, $H_{ex}$ and $T_{b}$ improve with 77-78 vol% Mn, but drop considerably with more Mn additions, losing magnetic properties of theb NiFe/IrMn/CoFe with addition 0.6 vol % Mn. The average x-ray diffraction peak ratios fcc (111)CoFe of (111)IrM $n_3$ textures for the Mn inserted total vol of 75, 77, and 79 vol% were about 1.4, 0.8, and 0.6, respectively. For the sample without Mn inserted layer, the $H_{ex}$ between I $r_{22}$M $n_{78}$ and CoFe layers is almost nothing. For two multilayer as-grown samples with ultra-thin Mn layers of 77 vol % and 79 vol %, the $H_{ex}$s are 250 Oe and 150 Oe, respectively. In case of IrMn with 77.5 vol% Mn, the $H_{ex}$ was 444 Oe up to 30$0^{\circ}C$ endured of 363 Oe at 40$0^{\circ}C$, respectively. Mn additions improve the magnetic properties and thermal stabilities of NiFe/IrMn/CoFe. Those increase the $H_{ex}$ and $T_{b}$. In applications where higher $H_{ex}$ and $T_{b}$ are accept, proper concentrations of Mn can be used.n can be used.be used.

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SURGICAL EXTRACTION OF MULTIPLE SUPERNUMERARY TEETH BY TWO-STAGE PROCEDURE (상악 절치부에 매복된 다수 과잉치의 외과적 발거)

  • Hong, Eun-Hye;Kim, Seong-Oh;Lee, Jae-Ho;Choi, Hyung-Jun;Son, Heung-Kyu;Choi, Byung-Jai
    • Journal of the korean academy of Pediatric Dentistry
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    • v.35 no.2
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    • pp.333-338
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    • 2008
  • Supernumerary teeth are characterized by an excess number of teeth, which can be responsible for a variety of irregularities in the primary and transitional dentition. Supernumerary teeth, especially in the maxillary anterior region, may prevent the eruption of adjacent permanent teeth and cause their ectopic eruption, diastema, root resorption, or formation of dentigerous cyst. Therefore, early diagnosis of supernumerary teeth is important for prevention of such complications, and adequate treatment should be given according to their location, number, and morphologic features. In this case, four supernumerary teeth in the maxillary anterior region were disturbing the eruption of adjacent permanent incisors. Two of them were located in proximity to the central incisor tooth germs that their immediate removal may injure the permanent tooth germs. In order to minimize such complications, surgical extraction of the four supernumerary teeth was performed in two stages. At first, only two inverted conical supernumerary teeth were extracted. The other two tuberculous supernumerary teeth, close to the permanent tooth germs, were extracted later after their natural dislocation. In that way, we could minimize affects on the neighboring permanent tooth germs and also the amount of alveolar bone removed during surgery.

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HRTEM Observations on the Modulated Structure in Pseudo-brookite-type Compound, $(In_{0.36}Zn_{1.09})Ti_2O_{5.64}$ (HRTEM에 의한 pseudo-brookite 형 화합물$(In_{0.36}Zn_{1.09})Ti_2O_{5.64}$에서의 변조구조 관찰)

  • Lee, Hwack-Joo;Park, Hyun-Min;Cho, Yang-Koo;Ryu, Hyun;Nahm, Sahn;Bando, Y.
    • Applied Microscopy
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    • v.29 no.1
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    • pp.95-103
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    • 1999
  • Microstructural observations on the pseudo-brookite $MgTi_2O_5$ and the similar type of $(In_{0.36}Zn_{1.09})Ti_2O_{5.64}$ were carried out using a top-entry HRTEM working at 200 kV. The modulated structures were found in $(In_{0.36}Zn_{1.09})Ti_2O_{5.64}$, however, not in $MgTi_2O_5$. The electron diffraction patterns of sublattice in $(In_{0.36}Zn_{1.09})Ti_2O_{5.64}$ are quite similar to those of pseudo-brookite $MgTi_2O_5$. but the complicated superlattice reflections are present in the diffraction patterns. Four types of modulations have been found. The periodicities for the modulated structure are found to be 3.63 nm, 0.79 nm and 0.64 nm along [220] direction, and 0.81 nm along [420] direction. The phase transition from the modulated structure to the unmodulated one was also observed in situ due to the electron beam irradiation reversibly. Further damage by the electron beam made the crystal to be fragmented into many small crystals with the formation of the voids at the kinks in ledged structure of the surface. The anisotropic arrangements of In and O atoms in $(In_{0.36}Zn_{1.09})Ti_2O_{5.64}$ might cause the compound to be unstable under the electron beam.

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Effect of Insoluble Dietary Fiber Extracted from Salicornia herbacea L. on Large Intestinal Function in Rats (불용성 함초 식이섬유의 섭취가 흰쥐 장기능에 미치는 효과)

  • Kim, Soo-Hwan;Kim, Sook-Ja;Lee, Hyeong-Seon
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.648-654
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    • 2014
  • This study investigated the effect of insoluble dietary fibers extracted from Salicornia herbacea L. (S. herbacea) on the improvement of intestinal function in rats. Sprague-Dawley rats were fed on diet containing 5% and 10% S. herbacea dietary fiber (SHDF) for four weeks. Rats receiving the SHDF diet showed a significant decrease in their triglyceride levels and an increase in HDL-cholesterol levels. In addition, compared with the control group, the SHDF group showed a significant increase in the total quantity of the feces and its moisture content. The intestinal transit time of the feces was also shorter in this group. The pH of the feces decreased in all the other experimental groups. Particularly, the bile acid content of the feces and the thicknesses of the mucus layers showed significant recovery on SHDF intake. These results suggest that dietary fiber isolated from S. herbacea has a marked effect on the improvement of bowel function in rats with loperamide (2 mg/kg)-induced constipation.