• Journal of Korea Society of Industrial Information Systems
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• v.20 no.3
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• pp.19-28
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• 2015

With the aim of developing a smartphone-based point-of-care device that is small, inexpensive, and easy to handle by non-expert, we designed a fluorescence smartscope for counting particles and a DC motor-controlled particle positioning system. Our smartscope can count the number of fluorescent particles and fluorescently-stained white blood cells through a phone camera with an adaptor containing a LED, a ball lens and optical filters and an application running on a smartphone. The motor was controlled wirelessly via Bluetooth with an Android smartphone. We found that axial spinning of a helical microfluidic channel allows arrangement of particles having size similar to the white blood cells. The motor-controlled particle positioning system can minimize time-consuming manual processes and automate sample preparation process and thus, if integrated with the smartscope, it can be used for a point-of-care testing device based on a smartphone.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.4
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• pp.715-722
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• 2022

If you don't regularly go to the dentist to check your teeth, it is difficult to notice cavities or various diseases of your teeth until you have pain or discomfort. Dental plaque is produced by the combination of food or foreign substances and bacteria in the mouth. Starch breaks down from the bacteria that form tartar. The acid that occurs at this time melts the enamel of the teeth and becomes a cavity. So tartar management is important. Poppyrin, the metabolism of bacteria in the mouth, reacts at 405 nm wavelengths and becomes red fluorescent, which can be seen by imaging through certain wavelength filters. By the above method, Frag and tartar are fluorescently detected and photographed with a yellow series of filters that pass wavelengths of 500 nm or more. It uses MATLAB to detect and display red fluorescence through image processing. Using the difference in voltage between normal teeth and tartar through an optical measuring circuit, it was connected to an Arduino and displayed on the LCD. This allows the user to know the presence and location of dental plaque more accurately.

• Optical Science and Technology
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• v.17 no.3
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• pp.5-8
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• 2013

• Proceedings of the Optical Society of Korea Conference
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• 2006.02a
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• pp.195-196
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• 2006

• Information Display
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• v.3 no.6
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• pp.24-29
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• 2002

PDP에 표시되는 영상의 화질은 PDP 구매 결정에 영향을 미치는 가장 중요한 요소들 중의 하나이다. PDP에서의 화질은 주로 PDP 구동방식, 셀의 구조, 사용되는 방전가스 및 형광체의 특성, 표시 가능 화소수 등과 같은 PDP 구성 요소들에 의해 좌우된다. 이와 같은 PDP의 구성 요소들을 개선함으로서 화질을 향상시킬 수 있다. 하지만, 이미 구성 요소들이 결정되어져 있는 경우 신호 및 영상 처리 방법들을 적용함으로서 PDP에서의 화질을 개선시킬 수 있다. 본 소고에서는 PDP에서의 고화질 구현을 위한 신호 및 영상처리 기술들을 소개하기로 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2018.10a
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• pp.480-481
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• 2018

치아는 식사 등의 일상생활에서 중요 역할을 하는 부위로 구강 건강을 지속적으로 관리하는 것이 중요하다. 최근 모바일에서는 의료 영상을 얻을 수 있을 만큼의 해상도를 갖춘 이미지를 얻을 수 있으며 디지털 의료기기로의 가능성을 보여준다. 본 연구에서는 스마트폰을 사용한 가시광선 영역의 파장대를 이용하여 치아의 초기 우식병소 진단에 도움을 받고 효율적인 관리를 할 수 있도록 하는 형광영상기반 치아분석시스템을 개발하였다. 시스템은 405 nm 파장대의 가시광선과 515 nm 이하의 단파장을 차단하는 필터를 고정하는 장치를 3D 프린터를 기술을 통해 고안 및 제작하여 스마트폰으로 치아의 영상을 얻고, 병소를 검출하여 정량적인 데이터를 제공한다. 제안한 시스템은 사용자의 시간적, 공간적 제약 없이 객관적인 데이터를 기반으로 사용자의 구강위생관리상태를 제시하여 조기진단 및 예방이 가능하다.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.5
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• pp.468-477
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• 2009

Purpose: Hydrodynamic-based procedure is a simple and effective gene delivery method to lead a high gene expression in liver tissue. Non-invasive imaging reporter gene system has been used widely with herpes simplex virus type 1 thymidine kinase (HSV1-tk) and its various substrates. In the present study, we investigated to image the expression of HSV1-tk gene with 5-(2-iodovinyD-2'-deoxyuridine (IVDU) in mouse liver by the hydrodynamicbased procedure. Materials and Methods: HSV1-tk or enhanced green fluorescence protein (EGFP) encoded plasmid DNA was transferred into the mouse liver by hydrodynaminc injection. At 24 h post-injection, RT-PCR, biodistribution, fluorescence imaging, nuclear imaging and digital wholebody autoradiography (DWBA) were performed to confirm transferred gene expression. Results: In RT-PCR assay using mRNA from the mouse liver, specific bands of HSV1-tk and EGFP gene were observed in HSV1-tk and EGFP expressing plasmid injected mouse, respectively. Higher uptake of radiolabeled IVDU was exhibited in liver of HSV1-tk gene transferred mouse by biodistribution study. In fluorescence imaging, the liver showed specific fluorescence signal in EGFP gene transferred mouse. Gamma-camera image and DWBA results showed that radiolabeled IVDU was accumulated in the liver of HSV1-tk gene transferred mouse. Conclusion: In this study, hydrodynamic-based procedure was effective in liver-specific gene delivery and it could be quantified with molecular imaging methods. Therefore, co-expression of HSV1-tk reporter gene and target gene by hydrodynamic-based procedure is expected to be a useful method for the evaluation of the target gene expression level with radiolabeled IVDU.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.66-69
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• 1998

Comparative genomic hybridization (CGH) is an important molecular cytogenetics technique that maps abnormal copy number of specific DNA sequence of the chromosome. CGH is based on quantitative digital image analysis of ratio images from fluorescently labeled chromosomes. In this paper, we would like to introduce how recently developed image analysis algorithms are used for CGH techniques. To average the ratio profile of each chromosome, binarization, skeletonization, and stretching of chromosome images have been studied. Developed algorithms have been implemented in the karyotyping system ChIPS commercially developed at Biomedlab Co. Ltd.

• Proceedings of the Optical Society of Korea Conference
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• 2009.02a
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• pp.533-534
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• 2009

• Polymer Science and Technology
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• v.25 no.2
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• pp.147-150
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• 2014