• Title/Summary/Keyword: 혈액유동

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THE RELATIVE IMPORTANCE OF NON-NEWTONIAN CHARACTERISTICS OF BLOOD IN THE HEMODYNAMICS OF THE CAROTID BIFURCATION (경동맥 혈류유동에서의 혈액의 비뉴우토니안 특성의 상대적 중요성 해석)

  • Lee, S.W.;Steinman, D.A.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03a
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    • pp.181-185
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    • 2008
  • In this study, we attempted to quantify the relative importance of assumptions regarding blood rheology. Three patient-specific carotid bifurcation geometries and time-varying flow rates were obtained using magnetic resonance imaging. For each subject, CFD simulations were carried out assuming two different non-Newtonian rheology models Carreau and Ballyk models) and rescaled Newtonian viscosities based on characteristic shear rates to account for the shear-thinning property of blood. The sensitivity of WSS and oscillatory shear index (OSI) were contextualized with respect to the reproducibility of the reconstructed geometry and to assumptions regarding the inlet boundary conditions. We conclude that the assumption of Newtonian fluid is reasonable for studies aimed at quantifying the distribution of WSS-based extrema in an image-based CFD model of carotid bifurcation.

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A Numerical Analysis on the Motion of a Curved Bileaflet in Mechanical Heart Valve(MHV) and the Characteristics of Blood Flow in an Elastic Blood Vessel (탄성혈관 내 곡면형 이엽 기계식 인공심장판막의 거동 및 혈액 유동 특성에 관한 수치해석적 연구)

  • Bang J. S.;Choi C. R.;Kim C. N.
    • 한국전산유체공학회:학술대회논문집
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    • 2004.10a
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    • pp.203-206
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    • 2004
  • In this study, a numerical analysis has been performed for a three-dimensional pulsatile blood flow associated with the elastic blood vessel and curved bileaflet for multiple cycles in terms of fluid-structure interaction. Here, blood has been assumed as a Newtonian, incompressible fluid. Pressure profiles have been used as boundary conditions at the ventricle and the aorta. From this analysis, the motion of the leaflet has been observed with fluttering phenomenon and rebound, and the flow fields of blood have been obtained with recirculation and regurgitation. The results can contribute to the development of design methodology for the curved bileaflet mechanical heart valve.

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THE RELATIVE IMPORTANCE OF NON-NEWTONIAN CHARACTERISTICS OF BLOOD IN THE HEMODYNAMICS OF THE CAROTID BIFURCATION (경동맥 혈류유동에서의 혈액의 비뉴우토니안 특성의 상대적 중요성 해석)

  • Lee, S.W.;Steinman, D.A.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.10a
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    • pp.181-185
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    • 2008
  • In this study, we attempted to quantify the relative importance of assumptions regarding blood rheology. Three patient-specific carotid bifurcation geometries and time-varying flow rates were obtained using magnetic resonance imaging. For each subject, CFD simulations were carried out assuming two different non-Newtonian rheology models (Carreau and Ballyk models) and rescaled Newtonian viscosities based on characteristic shear rates to account for the shear-thinning property of blood. The sensitivity of WSS and oscillatory shear index (OSI) were contextualized with respect to the reproducibility of the reconstructed geometry and to assumptions regarding the inlet boundary conditions. We conclude that the assumption of Newtonian fluid is reasonable for studies aimed at quantifying the distribution of WSS-based extrema in an image-based CFD model of carotid bifurcation.

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Analysis of hemodynamics in cerebral artery related to moyamoya disease (모야모야병과 연관된 뇌동맥에서의 혈류역학 분석)

  • Lee, Seung-Cheol;Lim, Ki-Moo;Shim, Eun-Bo
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1647-1650
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    • 2008
  • The moyamoya disease is a type of cerebrovascular disease which produces thin abnormal blood vessels like haze in the brain base because the end of internal carotid artery which supplies about 80% of blood is blocked. Regarding this moyamoya disease, the shearing stress and thrombus generation are mentioned as its main causes. This study three-dimensionally implemented the ICA, ACA, and MCA parts of the cerebrovascular configuration related to the moyamoya disease, and analyzed the hydrodynamic phenomenon with the commercial program ADINA. In particular, the correlations between shearing stress and speed distribution according to the branch angle of ACA and MCA. A numerical analysis found that the greater the branch angle of ACA and MCA, the lower the shearing stress and the greater the stationary area of the flow.. Put Abstract text here.

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Numerical Study of 3D Unsteady Flow in a Blood Sac of TPLS: Effect of Actuator Speed (TPLS 혈액주머니 내의 3차원 비정상유동에 대한 수치해석 연구: 액추에이터 속도의 영향)

  • Jung G. S.;Seong H. C.;Park M. S.;Ko H. J.;Shim E. B.;Min B. G.;Park C. Y.
    • 한국전산유체공학회:학술대회논문집
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    • 2003.08a
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    • pp.206-211
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    • 2003
  • This paper reports the numerical results for blood flow of the sac squeezed by moving actuator in the TPLS(Twin Pulse Life Support System). Blood flow in the sac is assumed to be 3-dimensional unsteady newtonian fluid. where the blood flow interacts with the sac, which is activated by the moving actuator. The flow field is simulated numerically by using the FEM code, ADINA. It is well known that hemolysis is closely related to shear stress acted on blood flow. According to this fact, we simulate four models with different speed for moving actuator and examine the distribution of shear stress for each model. Numerical results show that maximum shear stress is strongly dependent on the actuator speed.

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A Study on the Nutritional Assessment and the Effects of Enteral Nutritional Supports of Tube Feeding In-patients (경관급식 중인 입원환자의 영양상태 평가와 영양 보충제 투여의 영향에 관한 연구)

  • 윤숙영;김성미
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.5
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    • pp.855-864
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    • 1996
  • The purpose of this study is to evaluate nutritional status of tube feeding patients, and to investigate the effects of giving enteral nutritional support to them. 83 in-patients have been examined for their nutritional status. The mean caloric density was 0.77kca1/m1. 36.1% to 75.9% of them were malnourished in terms of biochemical assessment. The energy intake showed the significant and positive correlation in all biochemical parameters. And the protein intake showed the significant and positive correlation in total protein, serum albumin, serum iron, hemoglobin, hematocrit and TLC. But age was correlated negatively to serum albumin and transferrin. The amount of energy and protein intake has been significantly increased as the tube feeding duration became longer. Also the effect of enteral nutritional support for 6 weeks has been investigated. Case group(n=8) was administered 250kca1 of polymeric formula in addition to their usual diet, while control group(n=8) kept the amount of their original intake. When comparing the biochemical changes of the case group and those of control group at week 0 and week 6 respectively, it showed significant differences in total protein, serum transferrin and TLC. This study suggests that the malnourished status of tube feeding patients can be improved and even prevented if nutritional support is properly administered.

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램제트 엔진에서의 화염 전파와 비정상 연소 현상에 관한 수치해석

  • ;Vigor Yang
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2000.04a
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    • pp.10-10
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    • 2000
  • 램제트 엔진은 비추력이 높고 추력 레벨은 낮으므로, 2단 추진기관에 적합한 추진 시스템이다. 1단-추진기관의 작동이 끝나고, 2단 램제트 엔진이 점화 후 안정된 연소에 도달되기까지 비행체의 속도는 항력에 의하여, 초당 약 마하수 0.1 정도씩 감소된다. 1단 연소 후 2단 램제트로 전환되는 지연시간이 길수록 1단에서 요구되는 종말 가속도는 증가되므로, 1단이 차지하게되는 부피는 증가되고 비행체의 크기 또한 늘어나게 된다. 따라서 1단에서 2단 램제트로 천이되는데 소요되는 시간을 가능한 짧게 하는 것이 효과적이다. 그러나 램제트 엔진의 특성상 선결되어야할 다음과 같은 여러 문제들이 있다. 첫째, 1단 작동 시 공기 흡입구와 연소실은 차단벽으로 분리되어 있다가, 1단 연소후 차단막이 제거되어 외부공기가 램제트 연소실로 흡입된다. 흡입되는 공기는 흡입구의 형상에 의하여 램 압축되지만 초음속으로 연소실을 통과하게된다. 연료 주입 구에서 공급되는 연료는 연소실에서 유동의 흐름방향(streamline)에 따라서 연소실로 확산되는데, 연소되기 전에는 유속이 빠르게 노즐로 빠져 나가므로 램제트 연료가 재순환 구역(recirculation zone)으로 침투하는데 쉽지가 않다. 둘째, 연소실 입구에서 발생되는 와류 (ring vortex)는 1단 연료의 고온 연소 가스를 연소실로 확산시키는데, 비 균일한 온도 분포를 유발하여 램제트 연료의 점화에너지가 공급되는 시간이 적당하지 않을 경우 균일한 화염 전파에 악영향을 준다. 셋째, 연소실에서의 빠른 유동 조건은 연료가 연소실에 머무를 수 있는 시간을 감소시키며, 연소실 입구에서 강한 전단 응력이 발생되어 화염이 안정화되는데 악 영향을 미치게된다. 본 논문은 공기 흡입구, 연소실 및 노즐을 통합하여 수치해석을 하였으며 열유동/점화/연소등의 미케니즘을 이해하고, 주요 인자들 중 와류의 영향에 초점을 맞추었다.다고 판단되며 배기 가스 자체에 대기 공기중에 함유되어 있던 습기가 얼어붙는(Icing화) 문제가 발생하기 때문에 배기가스의 Icing을 방지하기 위하여 압축기 끝단에서 공기를 추출하여 배기부분에 송출할 필요성이 있는 것으로 판단되었다. 출구가스의 기체 유동속도가 매우 빠르므로 (100-l10m.sec) 이를 완화하기 위한 디퓨저의 설계가 요구된다고 판단된다. 또 연소기 후방에 물을 주입하는 경우 열교환기 및 기타 부분품에 발생할 수 있는 부식 및 열교환 효율 저하도 간과할 수 없는 문제로 파악되었다. 이러한 기술적 문제가 적절히 해결되는 경우 비활성 가스 제너레이터는 민수용으로는 대형 빌딩, 산림, 유조선 등의 화재에 매우 적절히 사용되어 질 수 있을 뿐 아니라 군사적으로도 군사작전 중 및 공군 기지의 화재 그리고 지하벙커에 설치되어 있는 고급 첨단 군사 장비 등의 화재 뿐 아니라 대간첩작전 등에 효과적으로 활용될 수 있을 것으로 판단된다.가 작으며, 본 연소관에 충전된 RDX/AP계 추진제의 경우 추진제의 습기투과에 의한 추진제 물성 변화는 미미한 것으로 나타났다.의 향상으로, 음성개선에 효과적이라고 사료되었으며, 이 방법이 편측 성대마비 환자의 효과적인 음성개선의 치료방법의 하나로 응용될 수 있으리라 생각된다..7%), 혈액투석, 식도부분절제술 및 위루술·위회장문합술을 시행한 경우가 각 1례(2.9%)씩이었다. 13) 심각한 합병증은 9례(26.5%)에서 보였는데 그중 식도협착증이 6례(17.6%), 급성신부전증 1례(2.9%), 종격동기흉과 폐염이 병발한 경우와 폐염이 각 1례(2.9%)였다. 14) 식도경 시행회수는 1회가 17례(54.8%), 2회가 9례(29.0%), 3회 이상이 5례(16.1%)였다.EX>$IC_{50}$/ 값이 210 $\mu\textrm{g}$/$m\ell$로서 효과적

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Acoustic Levitation and Rotation Produced by Ultrasonic Flexural Vibration (초음파 굽힘 진동에 의한 음향 부상 및 회전)

  • Loh, Byoung-Gook
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.14 no.5
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    • pp.432-438
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    • 2004
  • Acoustic levitation induced by ultrasonic flexural vibration at 28.4 KHz with a vibration amplitude of 10 micrometers is presented. Levitation of multiple objects along the length of the beam in a gap of 8.3 mm which is the half of acoustic wavelength is experimentally demonstrated. Analytical analysis predicts that levitated objects for the gap of half-the wavelength converges to the center of the gap, which is experimentally verified. It is observed that levitated objects with well-balanced mass distribution are set into rotation due to acoustic streaming. For cylinder-shaped Styrofoam with a diameter of 1.8 mm and a length of 3 mm, measured rotational velocity is 2400 revolution per minute. Applications of standing wave field levitation (SWFL) include manipulation of biological cells and blood constituents in biotechnology, and fine powder in material engineering.

Hemodynamical analysis by viscosity characteristics of artificial blood for μ-PIV experiment of Radio-cephalic arteriovenous fistula(RC-AVF) (μ-PIV기법을 이용한 동정맥루 모사혈관에서의 모사 혈액의 점도특성에 따른 혈류역학적 분석)

  • Song, Ryungeun;Lee, Jinkee
    • Journal of the Korean Society of Visualization
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    • v.14 no.1
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    • pp.33-39
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    • 2016
  • Radio-cephalic arteriovenous fistula(RC-AVF) is the most recommended operation of achieving access for hemodialysis. However, it has high rates of early failure depending on the many haemodynamic conditions. To increase RC-AVF patency rate, many researches were performed by in-vitro experiment via artificial vessel and blood analogue fluid, and there were conflicting opinions about whether the non-Newtonian properties of blood have an influence on the flow in large arteries. To investigate the influence of viscoelasticity of blood within the RC-AVF, we fabricated three dimensional artificial RC-AVF and two kinds of blood analogue fluid. The velocity field of two fluids within the vessel were measured by micro-particle velocimetry(m-PIV) and compared with each other. The velocity profiles of both fluids for systolic phase were matched well while those for diastolic phase did not correspond. Therefore, it is desired to use non-newtonian fluid for in-vitro experiment of RC-AVF.

Comparison of Steady and Physiological Blood Flow Characteristics in the Left Coronary Artery Bifurcation (좌관상동맥 분지부내의 정상혈류와 박동성혈류의 유동특성비교)

  • Suh, S.;Yoo, S.S.;Kwon, H.M.;Roh, H.W.
    • Proceedings of the KOSOMBE Conference
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    • v.1995 no.11
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    • pp.57-60
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    • 1995
  • The objective of this investigation is to understand the role of hemodynamics in the formation and development of atherosclerosis lesions in the human left coronary artery This study also aims to compare the blood flow characteristics of steady and physiological flows. Three dimensional, steady and physiological flows of blood in the left coronary artery are simulated using the Finite Volume Method. Apparent viscosity of blood is represented as a function of shear rate by the Carreau model. Distributions of velocity, pressure and shear stress in tile left coronary artery bifurcation are presented to compare tile steady and physiological flow characteristics.

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