• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.10
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• pp.1342-1346
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• 2009

This study was conducted to investigate the effect of Pepino extract on alcohol metabolism in male Sprague-Dawley rats. When the rats were given Pepino extract 30 min before 60% alcohol (4 g/kg B.W) administration, alcohol concentration in blood was significantly reduced, but acetaldehyde concentration was not significantly different, compared with the control group after 3 hrs of alcohol administration. When the rats were given Pepino extract ($1^{\circ},\;5^{\circ},\;10^{\circ},\;&\;15^{\circ}$ Brix) 30 min before 60% alcohol administration, alcohol concentration in blood with $1^{\circ}$ Brix Pepino extract was 44% after 3 hrs of alcohol administration, compared with the control group. When the rats were given with $1^{\circ}$ Brix Pepino extract at 30 min before 60% alcohol administration, alcohol concentration in blood was significantly reduced after one hour and acetaldehyde concentration was reduced by 19% after 5 hrs of alcohol administration, compared with the control group. Glutamate-oxaloacetate transaminase and glutamate-pyruvate transaminase activities were not significantly different in all experimental groups, compared with the control group. These results suggest that Pepino extract can be effective in alcohol metabolism in the alcohol-treated rats.

• Journal of Yeungnam Medical Science
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• v.6 no.2
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• pp.147-157
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• 1989

To investigate the blood lead concentration, their interrelation, correlation factor and influence on pregnant women and newborn, lead concentration in the maternal blood and umbilical cord blood were determined. Samples were collected from 130 mothers who were living in the Taegu City, during March, 1989. Blood lead concentration was estimated using the Atomic Absorption Spectrophotometer(IL. 551) equipped with Flameless Furnace Atomizer (IL. 665). The mean lead concentration of maternal and cord blood were $17.47{\pm}7.92{\mu}g/d{\ell}$, $15.31{\pm}7.98{\mu}g/d{\ell}$, respectively. A significant correlation was observed between the lead concentration of maternal and cord blood, r=0.663, Y=0.667X+3.646. No significant correlation was observed between previous spontaneous abortion and obstetric complication of mother and maternal blood lead concentration. Similarly, no significant correlation was observed between the sex, gestational age of neonate and cord blood lead concentration. But the birth weight of neonate had some negative correlation with cord blood lead concentration. The blood lead concentration of mother who had engaged in manufactures were higher than others and the longer working years were, the higher blood lead concentration were. Significant correlation was observed between husband's occupational exposure to lead and maternal blood lead concentration.

• Tuberculosis and Respiratory Diseases
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• v.51 no.1
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• pp.44-52
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• 2001

Background : Oxygen concentrators are convenient to operate and economical for patients with chronic obstructive pulmonary disease (COPD). However, oxygen concentrators are not manufactured domestically and the COPD patients are currently treated with imported oxygen concentrators. To evaluate the efficacy and safety of domestically developed prototype oxygen concentrator before clinical application, the efficacy and safety of the domestic oxygen concentrator were evaluate by comparing with the imported one. Material and Methods : The clinical tests were performed on 36 hyperhydrosis patients from April 1999 to August 1999. Domestic and imported oxygen concentrators were in turn applied to the same patient, who inspired oxygen for 60 minutes at a rate of 3 liters per minute through nasal prong. The oxygen concentrator, which was applied first, was randomly allocated. The arterial partial oxygen pressure ($PaO_2$) was estimated to compare the efficacy; and the carboxy hemoglobin(COHb), pH, arterial $CO_2$ partial pressure, pulse rate, blood pressure, and respiration rate to compare the safety before and after applying each oxygen concentrator. A student t-test was used to analyze the results. Result : In respect to efficacy, the difference in the change of $PaO_2$ before and after the application between two concentrators was not statistically significant. In respect to safety, the differences in the changes of COHb, pH, partial pressure of arterial $CO_2$, pulse rate, blood pressure, respiration rate between two concentrators were also not statistically significant. Conclusion : The domestically developed oxygen concentrator, showed satisfactory efficacy and safety when compared with the imported one.

• Journal of Chest Surgery
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• v.39 no.2 s.259
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• pp.117-126
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• 2006

Background: The purpose of this study is to describe the characteristics of malpractice claims related to hemopneumothorax and to identify the causes and potential preventability of such claims. Material and Method: A retrospective study was performed by reviewing the records in the Lawnb website and Lx CD-rom: the records on closed malpractice claims involving hemopneumothorax were abstracted from the files available for analysis. The records were reviewed and were analysed to determine the etiology of hemopneumothorax, patient age, results of lawsuit and indemnity payment, underlying diseases, cause of death or complications, and the factors associated with a successful defense. Result: Seven closed claim involving hemopneumothorax were founded in the data for malpractice. Three claims were supreme court decision, one was a high court decision and three claims were district court decision. The most common cause of death was tension pneumothorax. Four of which resulted in indemnity payments. Conclusion: While malpractice claims involving hemopneumothorax were uncommon, they resulted in a high rate and amount of indemnity payments. Claims are more common in pediatric patients. In case of iatrogenic hemopneumothorax, post-procedural X-ray can improve patient outcome and is also associated with decreased indemnity risks. Informed consent is also important.

• Applied Microscopy
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• v.36 no.4
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• pp.279-289
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• 2006

This study has been carried out to understand the effect of SP3 and GV6 acupuncture on the hyperglycemic rat induced with Streptozotocin (STZ). Diabetes was induced in experimental groups by inraperitoneal injection of STZ (50mg/kg of body weight) twice by 24 h interval and the additional 100mg/kg 3 days after the earlier treatment. Control group was treated with tail-non acupoint, and experimental groups were treated SP3, GV6 and SP3+GV6 after hyperglycemic induction for 6 weeks. The body weight of control was lower than the experimental groups. The blood glucose was decreased significantly in the experimental groups. Glucose tolerance in acupuncture treated groups was improved. Blood cholesterol level and transaminase activites were lower in the experimental groups than in the control. In the SP3 or GV6 treated rats, hepatocyte degeneration were apparently decreased and the organelles were properly arranged. Furthermore, decrease in liver IGF-I mRNA expression was improved by the acupuncture in STZ-induced diabetic rats. In conclusion, our observation indicate that SP3 or GV6 acupoints treatment can exert beneficial effects in diabetes, with preservation of ${\beta}-cell$ function and liver function.

• Journal of Naturopathy
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• v.10 no.1
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• pp.26-32
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• 2021

Purpose: At acupoint pressure, the pressing direction of all acupoints is usually vertical. However, it is not clear whether the vertical direction is toward the belly button or the body's center in the BL52. In this study, the effective direction of acupressure was studied by measuring the pressure pain threshold according to the direction of acupressure in 30 subjects. Methods: The distance from the subject's GV4 to the left and right BL52 and the distance from GV4 to the navel were measured, and then using the ellipse where the left and right BL52 of GV4 pass through the navel, the angles of the navel direction and the body's center were calculated in the left and right BL52. The pressure at the time when the subjects felt pain while pressing the BL52 in two directions was used as the acupressure pain threshold. The pain threshold was measured 3 times at 3 minute intervals on the left and right BL52s of the subject. Results: The acupressure pain threshold measured in the left and right BL52 of the subjects was significantly decreased when pressed toward the trunk center (p < .05). In BL52, it was more sensitive to pressure when the direction of pressure is toward the body's center. Conclusions: Acupressure therapy of acupoint is more sensitive to external stimuli than the surrounding. In this study, acupressure directed toward the trunk center is more efficient than toward the belly button in BL52.

• Journal of Acupuncture Research
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• v.27 no.3
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• pp.127-135
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• 2010

목적 : 이 연구는 알레르기 비염 또는 비부비동염으로 인한 비폐색증에 대한 침치료의 효과를 입증하고, 신혈인 심의혈의 임상적 효과를 알아보고자 시도하였다. 방법 : 2009년 9월 22일부터 11월 3일까지 2회 이상 경희의료원 동서비염클리닉에 내원하여 침 치료를 받은 비염환자를 대상으로, 무작위배정방법에 따라 실험군 또는 대조군으로 배정하였다. 실험군은 routine 혈위인 신회 상성 신정 양두유 양찬죽 양지창에 심의혈을 추가하였고, 대조군은 routine 혈위에 양영향을 추가하였다. 유침 시간은 각 군에서 15분간으로 하였다. 유효성 평가 도구로는 SNOT-20를 사용하여 비염의 전반적 증상 점수 변화를 측정하였고, VAS를 사용 하여 비폐색 완화 효과의 정도를 측정하였다. 평가시기는 치료 전후로 하였고, 통계분석은 치료 전후 SNOT-20 차이의 경우 Wilcoxon Signed Ranks Test로, VAS 비교는 Mann-Whitney Test를 이용하여 검정하였다.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.238-243
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• 1997

체중이 700-750kg 인 4마리의 중종마에 70분동안 마취를 실시하여 동맥혈의 이 산화탄소 분압과 호기말 가스내의 이산화탄소 분압 사이의 관계를 관찰하였다. 마취도중 자발 호흡, 인공호흡 1(흡기시간 2.0초), 인공호흡 2(흡기시간 2.5초)를 각각 30분,20분,20분씩 실시하였으며 매 10분마다 동맥혈가스분석과 호기말 가스내 이산화탄소분압 측정을 실시하 였다. 동시에 혈압, 심전도, 체온측정을 실시하여 마취된 환축의 상태를 관찰하였다. 2주후에 자세를 달리하여(앙와에서 측와로) 같은 방법으로 재 실험하였다. 호기말 이산화탄소분압은 동맥혈에서보다 평균 10 mmHg 정도 낮은 양상을 보였으나 높은 상관관계를 보였으며 자세에 따른 유의적 차이는 업었다(앙와자세; r=0.949, 측와자세; r=0.920, P<0.01). 이러한 결과를 토 대로 조직에 창상을 줄 수 있는 동맥혈 가스분석 대신 비침습적방법인 호기말 가스내 이산화 탄소 분압을 측정하는 것이 환축의 모니터링에 효과적으로 사용 가능하다는 것을 알 수 있었다.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.6 no.2
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• pp.76-80
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• 2013

It is very important to make an early diagnosis of acute hematogenous osteomyelitis in children to avoid various complications. We report a case of a five-year-old patient with tibial subperiosteal abscess, who was diagnosed using ultrasonography and treated at the early point of the disease.

• Korean journal of applied entomology
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• v.25 no.4 s.69
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• pp.215-220
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• 1986

Glucose, trehalose, and glycogen content were measured in haemolymph and the body during larval development of the oriental corn borer, Ostrinia furnacalis ($Guen\'{e}e$). Glucose content varied in haemolymph, but in the body it gradually decreased at all larval stages. As the larva proceeds growth, the initial high level of trehalose increased further in haemolymph whereas the low level trehalose gradually decreased in the body. Glycogen levels in haemolymph rose gradually during larval growth whereas those in the body increased sharply at the two latter instar larval stages. It is apparent that the existence of a homeostasis in carbohydrate levels between haemolymph ana the body.