• Journal of Life Science
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• v.17 no.4 s.84
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• pp.587-592
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• 2007

Manipulation of the mouse genome by activating or inactivating the gene has contributed to the understanding of the function of the gene in the subset of cells during embryonic development or postnatal period of life. Most of all, gene targeting, which largely depends on the availability of mouse embryonic stem (ES) cells, is the milestone of development of animal models for human disease. Recombinase-mediated genome modification (Cre-LoxP and Flp-Frt etc) and the ligand-dependent regulation system, more accurate and elaborate manipulation tools, have been successfully developed and applied to dissect the mechanisms governing complex biological processes and to understand the role of protein in temporal-and spatial aspects of development. As technologies concerning refined manipulation of mouse genome are developed, they are expected to open new opportunities to better understand the diverse in vivo functions of genes.

• Applied Chemistry for Engineering
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• v.8 no.6
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• pp.893-900
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• 1997

In this study, vapor-liquid equilibria of a binary system, which consists of glycerol and water, are measured using a vaporrecirculating modified Othmer still at various subatmospheric pressures. The constituent components of the binary system considered in this study exhibit a large difference in the boiling temperatures. Since it is generally observed that the properties of a mixture greatly differ from those of the pure components, the phase equilibrium characteristics of a mixture can not be predicted from the properties of the pure components. Furthermore, an abrupt increase in the boiling temperature occurs as the concentration of the higher boiling component exceeds a certain value. Therefore, it is essential to acquire realistic phase equilibrium data of the mixture for industrial applications. Using the UNIQUAC model, the experimental vapor-liquid equilibrium data are correlated with good accuracy. The thermodynamic consistency test is also performed to ensure soundness of the data.

• Korean Journal of Food Science and Technology
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• v.27 no.3
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• pp.324-328
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• 1995

The changes in the rheological properties of soybean curd upon the processing conditions were measured by the failure test, and analyzed by the stress-relaxation data. Soybean curd coagulated with $CaCl_2$ showed a higher failure stress value than other coagulants such as $MgCl_2,\;CaSO_4\;and\;Glucono-{\delta}-lactone$ (GDL), whereas addition of 0.3% $CaCl_2$ produced higher failure stress value than other concentrations $0.2{\sim}0.6%)$. Also, maximum failure stress of soybean curd was shown at the higher heating temperatures$(95^{\circ}C)$ and greater molding pressures, respectively. Initial and equilibrium stress at the stress relaxation curves showed the same tendency as those of failure test, and magnitude of elastic elements$(E_0,\;E_e)$ and viscous element$({\eta})$ were numerically expressed through simple Maxwell model analysis.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.8
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• pp.847-853
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• 2011

Filiform hairs that respond to movements of the surrounding medium are the mechanoreceptors commonly found in arthropods and vertebrates. The hairs function as a sensory system for perceiving information produced by prey, predators, or conspecifics. A mathematical model is proposed, and the parametric analyses for the response of artificial filiform hair are conducted to design and predict the performance of a microfabricated device. The results for the Cytop hair, one of the most popular polymer optical fibers (POFs), show that the fundamental mode has a dominant effect on the hair behavior in an oscillating medium flow. The dynamic behavior of sensory hair is also dependent on the physical dimensions such as length and diameter. It is found that the artificial hair with a high elastic modulus does not show a resonance in the biologically important frequency range.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.8
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• pp.670-677
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• 2017

In this paper, we propose a rotational motion compensation(RMC) for bistatic inverse synthetic aperture radar(Bi-ISAR) imaging. For this purpose, geometry-error, caused by changes of bistatic-angle, is removed using known position information of a transmitter, a receiver, and target trajectories. Next, RMC is performed to compensate non-uniform rotational motion error by reformatting radar signal in terms of a newly defined slow time variable that converts non-uniform rotational motion into uniform one. Simulation results using an aircraft model composed of ideal point scatterers validate the efficacy of the proposed Bi-ISAR RMC method.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.126-126
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• 2018

최근 우리나라는 기후변화로 인한 이상기후 현상 중 가뭄에 대한 발생빈도가 증가하고 있다. 가뭄은 다른 자연재해에 비해 지속기간이 길고 규모가 광범위하여, 사회 경제적인 피해가 크게 발생한다. 이러한 가뭄에 대비하기 위해서는 지역적으로 적합한 가뭄 대책을 수립해야 하며, 이를 위해서는 가뭄 위험도 평가가 선행되어야 한다. 지역적 가뭄 위험도를 평가하기 위해서는 기상학적 요인뿐만 아니라 사회 경제적인 요인에 의한 영향을 고려하는 가뭄 취약성 평가가 수반되어야 한다. 본 연구에서는 지역별 가뭄 취약성 평가를 수행하기 위해, 지역별 용수 수요 및 공급관련 인자와 선행연구에서 정의된 가뭄 위험인자들 중 8개(생활 농업 공업 용수공급량, 인구밀도, 1인당 가용수자원량, 물 자급률, 취수율, 물 이용 공평성)를 선택하였다. 베이지안 네트워크(Bayesian Network) 기법을 통해 선정된 사회 경제적 요인들과 가뭄과의 상관관계를 분석하여 각 지역의 특성을 고려한 가뭄 위험요인별 확률을 산정하였다. 최종적으로 산정된 주요 가뭄 위험요인별 확률을 우선순위에 따른 가중치를 적용하여 지역별 가뭄 취약성지수(Drought Vulnerability Index, DVI)를 산정하였고, 이를 이용하여 우리나라의 행정구역별로 취약성 평가를 수행하고 지도로 표시하였다. 지역별 가뭄 취약성 평가를 수행한 결과 익산, 상주, 완주 순으로 높게 나타났으며, 계룡, 과천, 종로순으로 가장 낮게 산정되었다. 또한 광역자치단체의 평균 가뭄 취약성지수를 산정한 결과 전라북도 지역이 가장 높게 나타났으며, 대구 및 대전광역시가 가장 낮게 나타났다.

• Food Engineering Progress
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• v.15 no.2
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• pp.116-121
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• 2011

This study was aimed to analyze the changes in rheological properties of sausages added tenderizer made with over-matured used-up fruits such as kiwifruit, grape, and pear. The tenderizers were manufactured by various concentration of fruit extract and added to the sausage at different heating temperatures. Failure stress and stress relaxation of beef sausage mixed with different tenderizers were measured with Rheometer, and analyzed with 3-element Maxwell model. As a result of the rheological measurements, over-matured kiwifruit extract showed the best tenderness effect among other fruit extracts, and the more kiwi contents were added, the beef texture turned to softer. The instantaneous stress and elastic component of beef mixed with various tenderizers were decreased at higher concentrations and lower heating temperatures. This study was well expressed the numerical magnitude of viscoelastic components of beef sausages to determine the tenderizer effect.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.381-381
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• 2020

자료동화(Data Assimilation) 기법은 실시간 수문학적 예측에 있어 정확도 향상을 위해 필수적인 과정이다. 가장 대중적으로 사용되는 기법들 중 하나가 모델 상태변수와 매개변수를 동시에 업데이트할 수 있는 이중 앙상블 칼만 필터(Dual Ensemble Kalman Filter)이다. 이 방법은 정확도 개선 및 적용의 용이성 때문에 많은 연구 분야에서 사용되어져 왔지만, 앙상블을 생성하는 과정에서 상당시간이 소요되는 단점이 존재한다. 본 연구에서는 상태변수와 매개변수를 동시에 업데이트 하면서 홍수 예측의 정확성을 보장할 뿐만 아니라, 앙상블 생성에 있어 계산 효율을 크게 향상시킬 수 있는 기법을 제안한다. Polynomial Chaos Expansion(PCE) 기법을 사용하여 앙상블 칼만 필터를 모방(mimic)할 수 있는 새로운 대체필터(Surrogate Filter)를 개발하는 것을 목표로 한다. 구체적으로 대체필터를 구성하기 위한 다양한 필터를 설계하였다. 첫째 시간에 대해서 PCE가 변화하지 않는 '불변 필터'(즉, 전체 예측기간에 대해 하나의 필터를 사용하여 자료동화할 수 있는 대체필터)와, 매 시간마다 PCE가 변화하는 '시변 필터'(즉, 예측하는 매 시간마다 새로운 필터를 생성해야 하는 대체필터)를 설계하여 적용성, 정확성, 예측성 등을 비교하였다. 또한, PCE의 하이퍼 매개변수를 최적화하기 위한 최적의 프레임 워크가 제안되어, 대체필터를 구축하는 데 효율을 높이고 PCE의 과적합(overfitting) 현상을 피할 수 있도록 하였다. 본 연구에서 제안된 기법은 기존 단일 및 이중 앙상블 칼만 필터(EnKF)의 결과와 비교 검증하였으며, 그 결과는 다음과 같다. (1) 대체필터의 대부분은 원래 EnKF와 비슷한 정도의 불확실성을 설명할 수 있음; (2) 모든 대체 필터는 선행시간이 짧은 경우의 예측에 있어 우수한 결과를 제공하며, 시변 필터가 불변 필터보다 더 정확한 예측 결과를 제공함; (3) 대체필터는 원래 앙상블 칼만필터보다 최대 500배 빠른 속도로 성능을 향상시킬 수 있음. 제안된 대체필터는 자료동화를 수행하는 기존필터와 비슷한 정도의 정확성, 매우 향상된 효율성을 보장함을 확인할 수 있었다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.6D
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• pp.915-922
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• 2008

Impervious surface is an important index for the estimation of urbanization and the assessment of environmental change. In addition, impervious surface influences on short-term rainfall-runoff model during rainy season in hydrology. Recently, the necessity of impervious surface estimation is increased because the effect of impervious surface is increased by rapid urbanization. In this study, impervious surface estimation is performed by using remote sensing image such as Landsat-7 ETM+image with $30m{\times}30m$ spatial resolution and satellite image with $1m{\times}1m$ spatial resolution based on Jungnangcheon basin. A tasseled cap transformation and NDVI(normalized difference vegetation index) transformation are applied to Landsat-7 ETM+ image to collect various predict variables. Moreover, the training data sets are collected by overlaying between Landsat-7 ETM+ image and satellite image, and CART(classification and regression tree) is applied to the training data sets. As a result, impervious surface prediction model is consisted and the impervious surface map is generated for Jungnangcheon basin.

• Journal of Music and Human Behavior
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• v.3 no.2
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• pp.29-44
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• 2006

Trust and understanding relationship promoted between a therapist and a client is the basic building block to successful recovery. Its importance is not only pertaining to the music therapy but also to counseling and psychological therapy. Because of its gnificance, broad spectrum of research has been conducted for quite a long time. Historically, researches have been focused on therapists or client's chological variables rather than emotional effects on each other that occur during the therapy session. Recently researchers turned their attention to emotional relationship between a therapist and a client. With recent advances in the field of music and psychological therapy, subsequent study has been conducted to investigate the role that music plays in the therapeutic relationship. For this research, eleven music therapy sessions were conducted for the adult females who are alcoholics. The first three sessions were of group therapy. Fourth to eleventh therapy session was done individually. Throughout the research case-by-case study has been conducted on the basis of the analysis of video and audio taped materials. Analysis depends heavily on its reference from the Amir's music research of 1990, which used Ferrara's seven phases of phenomenological study. Especially, verbal and nonverbal communications were closely analyzed in musical perspective. Research revealed that music and musical instruments act as a mediator between a therapist and a client. By doing so, it protects a therapist from unnecessary negative emotional displacements of a client and creates mutual reliability between a therapist and a client. Here, research suggests that music and musical instrument play a central role in building relationship between a therapist and a client, and it indicates that it has positive effect on treatment.