• Title/Summary/Keyword: 허가제

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Agreement of Label Information of Antihistamine, Anti-allergy Medications in Pregnancy among Korea, the USA, the UK, and Japan (임신부에서 항히스타민제와 알레르기용약의 국가별 안전정보 일치도 분석 : 한국, 미국, 영국, 일본 허가사항을 중심으로)

  • Park, Mi-Ju;Shin, Ju-Young;Kim, Hong-Ah;Park, Hyo-Ju;Kim, Mi-Hee;Shin, Sun-Mi;Park, Byung-Joo
    • Korean Journal of Clinical Pharmacy
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    • v.23 no.4
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    • pp.327-333
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    • 2013
  • Background: Antihistamine and anti-allergy medications are widely used during pregnancy. Reading label information is one of the easiest ways to get safety information. But there are content gaps among countries. Objective: To compare the risk level and the recommendation level of antihistamine/anti-allergy drug's label information in pregnant women among Korea, the USA, the UK, and Japan. Method: Study drugs of antihistamine/anti-allergy medications were selected according to Korea drug classification codes. Based on the label information of selected product, risk level was classified into 5 categories as follows: 'Definite', 'Probable', 'Possible', and 'Unlikely', 'Unclassified' according to the level of evidence. Recommendation level was classified into 4 categories as follows: 'Contraindicated', 'Cautious', 'Compatible', and 'Unclassified'. Frequency and proportion were presented according to the each category. To estimate agreement of each category among 4 countries, percent agreement and kappa (k) coefficient were calculated. Results: Total 13 drug ingredients were selected for antihistamine/anti-allergy medications. In risk level, Korea (46%) and Japan (69%) were mostly classified in the category of 'Unclassified', but 'Unlikely' category was more frequent in the UK (62%) and the USA (46%). In recommendation level, the proportion of 'Contraindicated' was highest in Korea (46%) compared to other countries. In contrast, the category of 'Cautious' was 77%-85% in the USA, the UK, and Japan. The percent agreement for risk level was highest in the USA-UK (54%). The recommendation level of Korea-USA showed lowest agreement for percent agreement (46%) and kappa coefficient (k=0.02). Conclusion: We confirmed the differences among safety information provided by four different countries. 'Contraindicated' was more likely in Korea compared with other countries.

A Study on the Permit Method for a New or an Enlarged Facilities According to the Implementation of Air Pollutant Emission-Cap Regulation in Metropolitan Area (수도권 사업장 대기총량제 시행에 따른 신·증설 사업장 허가기준 개발 연구)

  • Kim, Hong-Rok;Yoon, Young-Bong;Ko, Byung-Churl;Shin, Won-Geun;Kim, Dong-Joong;Lee, Myung-Hwoon
    • Journal of Environmental Impact Assessment
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    • v.16 no.4
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    • pp.301-310
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    • 2007
  • For the improvement of air quality in the metropolitan area, Korea has enforced the air pollutant emission cap regulation from the 1st of July, 2007, and the companies that intend to install a new or an enlarged facility in the metropolitan area will be restricted. However, the current regulation on permission does not describe a standard of judgement distinctly. In this study, therefore, a method of permission on the installation of a new or an enlarged facility was developed by supplementing the law in force based on the foreign cases. To develop a specific permit regulation and procedure, the developed nations' cases such as US, Canada, EU were reviewed thoroughly. Also, an appropriate method was suggested to apply domestically for a new or an enlarged facility permit within the regulations of the metropolitan special law. The method consists of first, calculating the possible permit quantity from the difference between an estimated annual emission cap and the annual emission provided by the implementation plan in each region. Second, permitting a new or an enlarged facility construction within the difference of the emission between the regional emission cap and the implementation plan in 2014. Third, distributing emissions allowable to each performance year based on the regional emission cap and the implementation plan in 2014. Fourth, making use of the emission difference between the implementation plan and the performance result in each year. Considering the general domestic conditions, the convenience of the permit authority and permitted companies, the most reasonable method was to use the fourth. To enforce the suggested permit method in a more flexible way, parts of the related regulations need to be revised and continuous research and analysis on the results from the implemented system and on foreign cases is necessary to develop this method a suitable system for domestic conditions and to settle the air pollutant emission cap system.

Application of PSL-TL Combined Detection Method on irradiated Composite Seasoning Products and Spices (방사선 조사 복합조미식품과 향신료의 확인을 위한 PSL-TL의 적용)

  • Chung, Hyung-Wook;Park, Sung-Kug;Han, Sang-Bae;Choi, Dong-Mi;Lee, Dong-Ha
    • Journal of Food Hygiene and Safety
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    • v.23 no.3
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    • pp.206-211
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    • 2008
  • Photostimulated luminescence(PSL)-Thermoluminescence(TL) combined analysis was applied to detect whether composite seasoning products and spices were irradiated or not. Samples were irradiated with $^{60}Co$ at $0{\sim}7$ kGy. A total of 12 different samples(6 of composite seasoning products and 6 of spices) was examined. Depending on the PSL results, TL analysis was performed. In case of both PSL positive(${\geq}5,000$ counts) and intermediate($700{\sim}5000$ counts), TL analysis had to be performed to confirm the result of PSL. Using TL, the shape of the glow curve(Glow 1) made it possible to identify the irradiated samples. In addition, The TL glow ratio(Glow 1/Glow 2) obtained by normalization was less than 0.1 for the non-irradiated samples and ${\geq}0.29$ for irradiated ones, respectively.

A Study on the Operational Way of Freight Forwarding Company: Focusing on Residental Moving Company (화물운송주선업체의 운영방안에 관한 연구 - 이사화물운송주선업체를 중심으로 -)

  • Moon, Jong-Ryoung;Jung, Hyun-Jae;Lee, Tae-Hwee;Kim, Young-Hwan;Yeo, Gi-Tae
    • Journal of Korea Port Economic Association
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    • v.26 no.3
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    • pp.221-239
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    • 2010
  • This study aims to provide solutions concerned with to residential moving companies about their operational problems. In order to shed light on these problem, factor analysis and fuzzy AHP method are adopted. Selected factors are low quality of workers and equipments, weak condition of business, policy and form of a contract, and excessive competition. The results of survey show that excessive competition is the most urgent problem compared with other problems. In the twelve-measured variables, The problem of non-certificated firms, low service quality caused by excessive competition, and claims caused by lack of service instruction are chosen as the urgent matters. As a result of the analyses, the study would propose policy directions how to solve these problems. Firstly, the government should make the legal basis of operating the industry because there is too competitive in the field. Secondly, the government should regulate firms which have not a certificate because they are the cause of low service quality in the field. Thirdly, in order to improve the service quality, the study would suggest that the managers should instruct the workers of residential moving companies. Lastly, the paper would suggest that customers check the certificate of the firm allowed by the government authorities.

A Study on the Improving Management Method for the Small Projects Applying Senior Construction Engineer (고령 건설기술자를 활용한 소규모공사의 공사관리방법 개선에 관한 연구)

  • Song Jin-Woo;Lee Sang-Beom
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2004.11a
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    • pp.305-310
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    • 2004
  • The building below standard scales to be built only by constructive report to authorities. Construction law 8 illustrates that supervision should be deployed in all the construction sites at the building which is found to have more than 3 floors and also to have more than $200m^2$ of total squares in especially outside area of city plan zone. Such a small construction is have a important and the most basic meaning. Many problems were found to occur in all the constructive places which were out of the limit of this law. The construction sites were found to be controlled by public official's visiting without supervisors and designers of architecture. Technique of construction in architecture was found to be not different from that of 1980. The security of employees in construction on sites has a serious problem. Because of choosing all the materials of the building without a reasonable point. All the building were found to have a law material about inside and outside aspects. The purpose of this study are to examine existing law about a small project and than to analyze the situation of constructive control through questionnaires and interviews with all the supervisors. Based on the data base of engineers who had a great experience in construction sites, The purpose of this study is also to suggest and advise the method of controlling all the items in architecture through on and off line.

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A Study on Land price stabilization plan by Developing Prediction model of Land price -Focusing on Jeju special delf-governing province- (토지가격 예측 모형 개발을 통한 토지가격 안정화 방안 연구 -제주특별자치도를 중심으로-)

  • Kang, Kwon-Oh;Yang, Jeong-Cheol;Hwang, Kyung-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.10
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    • pp.170-177
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    • 2017
  • The price of land in Jeju is reaching a new high every day and this phenomenon not only causes real difficulties for the purchase of real estate by local residents, but also results in psychological deprivation. Therefore, this study analyzes the factors causing the increase of the land price in Jeju, in order to examine the measures required to stabilize the land price which is continuously rising. As a result of this study, we developed a land price prediction model including seven variables, including the 'inflation rate', 'interest rate', and 'population'. According to the model, land prices in Jeju are expected to rise steadily, and it is predicted that in 2020 the price will increase to 170% of that in 2015 and will triple by 2025. Based on the results of this study, this study suggested policy alternatives, such as 'Establishing a tourism policy for managing the number of tourists' and 'increasing the approval standards for development activities'. The two policies proposed in this study can be implemented as a regional initiative, which may be less effective than the changes in the national system, but it is meaningful that the efforts to stabilize the land price will continue at the regional level.

Image Encryption and Decryption System using Frequency Phase Encoding and Phase Wrapping Method (주파수 위상 부호화와 위상 랩핑 방법을 이용한 영상 암호화 및 복호화 시스템)

  • Seo, Dong-Hoan;Shin, Chang-Mok;Cho, Kyu-Bo
    • Korean Journal of Optics and Photonics
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    • v.17 no.6
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    • pp.507-513
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    • 2006
  • In this paper, we propose an improved image encryption and fault-tolerance decryption method using phase wrapping and phase encoding in the frequency domain. To generate an encrypted image, an encrypting key which denotes the product of a phase-encoded virtual image, not an original image, and a random phase image is zero-padded and Fourier transformed and its real-valued data is phase-encoded. The decryption process is simply performed by performing the inverse Fourier transform for multiplication of the encrypted key with the decrypting key, made of the proposed phase wrapping method, in the output plane with a spatial filter. This process has the advantages of solving optical alignment and pixel-to-pixel mapping problems. The proposed method using the virtual image, which does not contain any information from the original image, prevents the possibility of counterfeiting from unauthorized people and also can be used as a current spatial light modulator technology by phase encoding of the real-valued data. Computer simulations show the validity of the encryption scheme and the robustness to noise of the encrypted key or the decryption key in the proposed technique.

A Cost-Benefit Analysis on the Introduction of EU REACH to Korea (EU 신화학물질정책(REACH) 도입에 대한 비용편익 분석)

  • Cheong, Hoe-Seog
    • Journal of Environmental Policy
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    • v.8 no.3
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    • pp.53-79
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    • 2009
  • This study conducted a regulatory impact analysis regarding the introduction of the Korean version of REACH(Registration, Evaluation and Authorization of Chemicals). The direct cost of the Korean REACH is estimated at a total of 101 billion Korean won over the 11 year period. The cost includes pre-registration, testing, registration, Chemical Safety Assessment(CSA) and Chemical Safety Report(CSR), evaluation, and the authorization costs of 15,223 chemical substances produced and imported more than 1 ton per year in Korea in 2006. With regard to the benefit, the only public health benefit is included in the estimation. Based on the available foreign and domestic data, this study estimated that the economic values of public health benefits are in the range of 33.2~138.6 billion Korean won if only the savings of the National Health Expenditures are considered and it reaches 203.9~1,640.3 billion Korean won if the willingness to pay(WTP) for disease prevention is included. This study proved that the Korean REACH passed the cost/benefit criteria. The benefit-cost ratio of the Korean REACH, however, is estimated to be lower than its EU counterpart. Thus it is suggested that a rigorous study to reduce the costs to industry be required before the Korean government introduces the Korean REACH.

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Indonesia's REDD+ National Strategy between Ideal and Reality (인도네시아 REDD+ 국가 전략의 이상과 현실)

  • Bae, Jae Soo
    • Journal of Korean Society of Forest Science
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    • v.102 no.2
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    • pp.189-197
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    • 2013
  • The Cancun Agreements under the United Nations Framework Convention on Climate Change require developing countries aiming to undertake REDD+ activities to develop a national strategy or action plan, addressing the drivers of deforestation and forest degradation, a measurement, reporting and verifying (MRV) system including forest monitoring system, and safeguards to ensure equity and co-benefits for local communities and indigenous peoples, and biodiversity. The Government of Indonesia and the Government of Norway established REDD+ cooperation through signing a 'Letter of Intent' in May, 2010. Indonesia agreed on 'a two year suspension on all new concessions for conversion of peat and natural forest'. In turn, Norway agreed to support Indonesia's REDD+ implementation efforts up to one billion United States dollars. Indonesia's REDD+ national strategy (June, 2012) accepted most of the requests included in the 'Letter of Intent'. The REDD+ national strategy, however, does not reflect requests of the Cancun Agreements which noted identification of the drivers of deforestation and forest degradation and guarantee of real greenhouse gas emissions reductions. Indonesia lays emphasis on Norwegian requests which includes expected financial support rather than the Cancun Agreements which have a weak legally-binding requirements.

The French Evolution of Protection-Management Systems for Historic Monuments and Their Surroundings over One-Hundred Years: 1913-2016 (프랑스 역사기념물과 그 주변 보호·관리제도의 진화: 1913~2016)

  • Lee, Sujin;Ryu, Je-hun
    • Korean Journal of Heritage: History & Science
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    • v.52 no.3
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    • pp.94-111
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    • 2019
  • This study aims to examine the evolutionary process of the protection-management system for historic monuments and their surroundings in France over one-hundred years. Because France and Korea shared policies and institutions regarding the management of historical monuments (cultural property) along with their surroundings, it is necessary to explore the French experience from a comparative perspective. In France, historical monuments began to be recognized as national heritage according to "the 1913 law" which has continued to evolve for more than one hundred years. In the beginning, a historical monument was preserved as a single building unit; however, since 1943, a new policy has been implemented to preserve sets of historical monuments along with their perimeters of protection zones. Moreover, since 1980, in the context of decentralization, local authorities have been given more roles and autonomy concerning the management of historic monuments and their surroundings. Local authorities have played a key role in the protection-management of historic monuments and their surroundings, and have become more active in the conservation of their architectural heritage, including historic monuments. The central government, however, remains as the headquarters whose rigorous policies provide a solid foundation for the decentralized management system of architectural and cultural heritage, including historic monuments. The final goal in the evolutionary process, then, targets the effective and harmonious integration of the protection-management system for historic monuments and their surroundings into urban and regional planning.