• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.5
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• pp.605-611
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• 2012

Sea cucumber, $Stichopus$ $japonicus$, is used not only as an outstanding tonic food but also as a traditional medicine for the treatment of asthma, hypertension, rheumatism, anemia, and sinus congestion. The purpose of this study was to examine sea cucumber as an anti-gastritis and anti-gastric ulcer in HCl-ethanol-induced gastric and $H.$ $pylori$-infected animal models. Thirty 7-week-old SD rats and Mongolian gerbils were divided into normal (Nor, n=6), control (Con, 60% HCl-ethanol+water, n=6), groupI (DSCI, 60% HCl-ethanol+sea cucumber 30 mg/kg, n=6), groupII (DSCII, 60% HCl-ethanol+sea cucumber 100 mg/kg, n=6), and group III (DSCIII, 60% HCl-ethanol+sea cucumber 300 mg/kg, n=6). Sea cucumber significantly suppressed gastric lesions and ulcers in the 60% HCl-ethanol-induced gastric model. Especially, 100 mg/kg of sea cucumber showed significantly inhibitory effects. In histopathological analysis of the $H.$ $pylori$ model, we found that sea cucumber augmented the eradication rates of $H.$ $pylori$ and attenuated gastric ulcer formation. Our results suggest that sea cucumber has inhibitory effects on gastritis and gastric ulcers. In addition, sea cucumber can be applied for the treatment of $H.$ $pylori$.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.9 no.3
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• pp.93-105
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• 2004

Spatio-temporal distribution patterns of the major dominant species were assessed from bimonthly monitoring of macrotidal flat in Cheokjeon, Incheon, Korea between September 1990 and July 1992. Overall, macrofauna comprised a total of 111 species, 25,491 inds.136 ㎡. The result of Le Bris index, dominance ranking of the lead-ing species showed that the top 15 species accounting for 74.8% (19,072 inds.) of total density. In Cheokjeon tidal flat, some species were especially habitat-restricted such as genus Nephtys (Annelids; Polychaetes) and Mac-rophthalmus (Crustaceans; Decapods). Based on the density data, the five dominant species were the polychaetes Het-eromastus filiformis, the bivalves Mactra veneriformis and Solen strictus, the brachyurans Macrophthalmus japonicus, the holothuriodeans Protankyra bidentata. The results of one-way ANOVA, mean value of H. filiformis and M. ven-eriformis did not show significant changes with tidal elevation and sediment composition (p>0.05). But, other species (S. strictus, M. japonicus and P. bidentata) showed significant variations (p<0.001). In conclusion, these indicate significant spatial fluctuation with tidal elevation and sediment characteristics in some species.