• Title/Summary/Keyword: 항산화효소 활성

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The Effects of Aerobic Training Intensity Difference on Cardiovascular Disease Pathophysiological Pathways Linking Oxidative Tissue Damage in Obese Children (유산소 훈련 강도 차이가 비만 어린이의 산화적 조직 손상에 의한 심혈관질환 병태생리적 경로에 미치는 영향)

  • Woo, Jin-Hee;Shin, Ki-Ok;Kim, Keun-Soo;Kim, Young-Il;Kang, Sung-Hwun
    • Journal of Life Science
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    • v.20 no.9
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    • pp.1394-1401
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    • 2010

  • The purpose of this study was to examine the effect of 12 wk of aerobic exercise on lipid profiles, antioxidant enzyme activities, oxidative products, and autonomic nervous activity (ANA) in children with obesity. We studied 16 children with obesity and 19 age-matched normal weight controls over a period of 12 wk, during which time moderate intense running exercise was performed. Measurements included peak oxygen uptake, body composition, blood lipid profiles, ox-LDL, 8-OHdG, SOD, GPx activities, total mRNA, and ANA. There were no differences in body weight between periods in the OW group, but body weight increased after 12 wk in OR and CO groups. There were no differences in WHR between periods in the OR and CO groups, but the WHR values decreased after 12 weeks in the OW group. In the obese group, the baseline TG was higher than in the controls (p<0.05), while the ANA level was lower. There were differences in antioxidant enzyme gene expressions between periods in all groups. In conclusion, oxidative damage and antioxidant enzyme activities in obese children were found to be similar to those of normal weight children. However, TG was higher and ANA was lower in obese children than in normal weight children. These results indicated that increased TG and decreased ANA levels begins in childhood in obese patients. Also, regular aerobic exercise may modify the antioxidant enzyme gene expression in early life.

  • https://doi.org/10.5352/JLS.2010.20.9.1394 인용 PDF KSCI

Effect of Aerobic Exercise with Resistance Exercise Programs on Blood MDA and SOD, GPx Activities in Elderly Women (유산소 운동을 병행한 근 저항성 운동이 노인 여성의 혈중 MDA 및 SOD, GPx 활성에 미치는 영향)

  • Nan, Sang-Nam;Kim, Jong-Hyuck;Ji, Min-Cheul
    • The Journal of the Korea Contents Association
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    • v.9 no.11
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    • pp.391-398
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    • 2009

  • The purpose of this study was to investigate the effects of aerobic exercise(folk dance) with resistance exercise(elastic band) for 12 weeks on blood MDA concentration and SOD GPx activities in the elderly women. The subjects consisted 12 elderly women between 65-75 years exercise were folk dance(HRmax 50-60% levels, 60min, two per a week) and elastic band(yellow band, 60min, two per a week) program for 12 weeks. SOD, GPx activities in the before combined exercise were significantly increased than that in after combined exercise. These results show that aerobic exercise with resistance exercise program in considered to contribute enforced of antioxidant enzyme system by increased SOD and GPx activities in elderly women.

  • https://doi.org/10.5392/JKCA.2009.9.11.391 인용 PDF