• Title/Summary/Keyword: 항균특성

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Anti-bacterial properties of $Na_2O-CaO-TiO_2-P_2O_5$ glass added in Ag (Ag를 첨가에 따른 $Na_2O-CaO-TiO_2-P_2O_5$계 글라스의 항균특성)

  • Yoo, Eun-Sung;Kang, Won-Ho
    • Proceedings of the KAIS Fall Conference
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    • 2008.11a
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    • pp.90-92
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    • 2008
  • 본 논문에서는$xAg_2O$-(5-x)$Na_2O$-36CaO-$10TiO_2$-$19.5P_2O_5$ (mol ratio)의 유리조성으로부터 $Ag_2O$의 함량을 변화시켜 유리의 제조 및 특성평가를 하였다. 제조된 유리는 TG-DSC를 통하여 열적특성을 관찰하였으며, 항균특성은 staphylococcus aureus균주에 대하여 항균특성을 평가하였다. 평가결과 열적특성은 $Ag_2O$함량이 증가할수록 결정화온도가 낮아짐이 관찰되었고, 항균특성 역시 $Ag_2O$성분의 함량이 증가 할수록 항균특성이 증가하는 것으로 관찰되었다.

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Development of antimicrobial edible films and coatings: a review (항균 가식성 필름/코팅 개발 현황)

  • Kim, Su Yeon;Min, Sea C.
    • Food Science and Industry
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    • v.50 no.2
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    • pp.37-51
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    • 2017
  • Food packaging strategies have steadily improved with increasing demand for improved food safety, convenience, and shelf life. The development of edible film has been hailed as a technology substituting packaging using synthetic plastics. There has been a surge for research to develop antimicrobial edible films and coatings that can increase microbiological safety while preserving foods. This review addresses recent results that are useful in advancing and extending research into antimicrobial edible films. In this review, we suggest the trend of the development of antimicrobial edible film/coatings by outlining edible film materials, antimicrobial substances, antimicrobial and physical properties of the films, commercial antimicrobial edible films, and methods to statistically predict the efficacy of antimicrobial edible film/coatings, reported in recent studies.

새로운 퀴놀론 항균제의 합성

  • 강석구
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.227-227
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    • 1994
  • 퀴놀론계 항균제란 퀴놀린 이나 나프티리딘 핵을 갖고 있는 화합물로써 항균효과를 나타내는 물질을 의미한다. 이러한 퀴놀론계 항균제의 구조적 특성에 따라 항균활성의 영향은 ASAR에 의하여 이미 구조적 제한성을 가지고 있다고 보고 되어있다. 본 연구에서는 Drug-Enzyme inleraetion domain을 변화시킴으로서 보다 강력한 항균제를 찾아낼수 있을 것으로 판단하고, 기존 항균제가 C-7에 piperazine이 있으므로 piperazine의 chemical isoster 또는 bioisoster의 개념하에서 C-7에 도입한 아민류를 분자설계하고 합성하여 새로운 퀴놀론계 항균제를 만들어 내고자 하였으며 target molecule은 다음 그림과 같다.

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$50P_2$$O_{5}$.(10-40)$Na_2O$.(10-40)CuO Glass의 항균 특성

  • 윤영진;이용수;강원호
    • Proceedings of the KAIS Fall Conference
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    • 2001.05a
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    • pp.37-39
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    • 2001
  • 구리 이온을 함유한 XCuOㆍ(50-X) Na₂Oㆍ50P₂O/sub 5/ 조성을 승온속도 10K/min로 900℃까지 숭온한 후 1시간동안 유지하여 용융하였으며, 연속적으로 가열되어진 흑연판에 부어 급냉함으로써 모유리를 제조하였다. 제조된 유리를 분말상의 시편으로 만들어 상온에서 증류수로 3일동안 용해시켰다. 각각의 조성에 따른 살균효과를 측정하였으며, 제조된 시편을 소지토에 첨가하여 그 항균특성을 관찰하였다. 항균특성 평가를 위하여 사용된 균주는 Staphylococcus aureus 와 Salmonella typhi가 사용되었으며, Staphylococcus aureus 균주에 대해서는 모든 시편 담지후 3시간 이후에, Salmonella typhi에 대해서는 6시간 이후에 모든 균이 소멸되는 것으로 관찰되었다.

Preparation of Nickel Coated-carbon Nanotube/Zinc Oxide Nanocomposites and Their Antimicrobial and Mechanical Properties (니켈 코팅된 탄소나노튜브/산화아연 나노복합소재의 제조와 항균 및 기계적 특성 분석)

  • Kim, Hyeon-Hye;Han, Woong;An, Kay-Hyeok;Kim, Byung-Joo
    • Applied Chemistry for Engineering
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    • v.27 no.5
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    • pp.502-507
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    • 2016
  • This study was conducted to develop novel antimicrobial nano-composites, with the aim of fully utilizing antimicrobial properties of multi-walled carbon nanotubes (MWCNTs), nickel (Ni) and zinc oxide (ZnO). Ni coated-MWCNTs (Ni-CNT) were prepared and evaluated for their potential application as an antimicrobial material for inactivating bacteria. Field emission scanning electron microscopy (FE-SEM), and X-ray energy dispersive spectroscopy (EDS) were used to characterize the Ni coating and morphology of Ni-CNT. Staphylococcus aureus (S. aureus) and Escherichia coil (E. coil) were employed as the target bacterium on antimicrobial activities. Comparing with the nitric acid treated MWCNTs and Ni-CNT which have been previously reported to possess antimicrobial activity towards S. aureus and E. coil, Ni-CNT/ZnO exhibited a stronger antimicrobial ability. The nickel coating was confirmed to play an important role in the bactericidal action of Ni-CNTs/ZnO composites. Also, the addition of ZnO to the developed nanocomposite is suggested to improve the antimicrobial property.

The Biocidal Activity of Nano-sized Silver Particles Comparing with Silver Ion (은 이온과의 비교를 통한 나노 은 입자의 항균 특성 연구)

  • Kim, Jee-Yeon;Kim, Sung-Eun;Kim, Jae-Eun;Lee, Jong-Chan;Yoon, Je-Yong
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.7
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    • pp.771-776
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    • 2005
  • In recent days, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinfectant and biocidal material against coliforms and viruses. In particular, nano silted silver particles which can be used as effective biocidal material received more attention. Accordingly, it is important to investigate antimicrobial activity and mechanism of nano sized silver particles prepared in a cost-effective manner. In this study, nano sized silver particles were prepared via photoreduction of a silver salt ($AgNO_3$) in the bulk phase of $PEO_{20}-PPO_{70}-PEO_{20}$ (Pluronic 123) block copolymer The antimicrobial efficacy of silver nano particles against E. coli was investigated and compared with that of silver ion as the concentration of silver nano particles, pH ($5.6{\sim}8.2$), temperature ($4^{\circ}C{\sim}35^{\circ}C$) varied in aqueous system. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) was used to examine the nature of damaged microorganism with nano sized silver particles and silver ion. This study showed that antimicrobial efficacy of silver nano particles was approximately one twentieth than that of silver ion. It was more biocidal at higher pH in contrast with silver ion. In addition, nano silver particles was demonstrated to disrupt the outer membrane of E. coli, subsequently causing their aggregation. On the other hand, silver ion diffused into the cell damaging the cytoplasmic membrane without disrupting the outer membrane of E. coli.