• Herbal Formula Science
• /
• v.18 no.1
• /
• pp.43-56
• /
• 2010

Objective : There is a growing need to expand or adjust insurance coverage of herbal prescriptions in National Health Insurance. The purpose of this study was to provide basic data for expansions or adjustments of 56 herbal prescriptions in the National Health Insurance. Method : We surveyed lists of 56 insurance-covered herbal prescriptions, non-covered company-produced herbal medicines and self-prepared herbal medicines in 531 traditional korean medical clinics by mail from 6/1/2008 to 12/9/2008. Result : Among the 56 Prescriptions, Ojeok-san was stocked in 66.7% of clinics (1st), Samso-eum ranked 2nd, Socheongnyong-tang ranked 3rd, Gumiganghwal-tang was 4th, Hyangsapyeongwi-san ranked 5th. Among the non-covered company-produced herbal medicines, Danggwisu-san ranked 1st, Gwakyangjeonggi-san ranked 2nd, Oryeong-san was 3rd, Bangpungtongseong-san was 4th, Maengmundong-tang ranked 5th. Among the self-prepared herbal medicines, Gongjin-dan ranked 1st, Soche-hwan was 2nd, Gyejibongnyeong-hwan was 3rd, Yeongsin-hwan was 4th, Palmi-hwan ranked 5th. Conclusions : It is reasonable to select frequently used company-produced or self-prepared herbal prescriptions in this stock rate survey for improvement of National Health Insurance coverage.

• The Korea Journal of Herbology
• /
• v.21 no.4
• /
• pp.1-10
• /
• 2006

Objectives : Recently, the total medical expenses of the korean oriental medical service in national health insurance is on the increase every year. Herbal medicines are one of the major methods of the medical treatment. But the expenses of these herbal preparations that can receive benefits from insurance system are decreasing. Methods : In this research, we obtained statistical data of the benefit states of herbal preparations in herbal heath insurance during year 2001-2003 from Health Insurance Review Agency. We analyzed top twenty main diseases in herbal health insurance and mainly used prescription in these diseases. Results : There were wide differences in the application of prescriptions among diseases. For example, musculoskeletal diseases occupied an important position and Ojucksan took more than 50 percentage. Conclusion : We hope that this study could be a basic data for improving the benefit system of herbal health insurance and further studies should be carried out subsequently.

• Herbal Formula Science
• /
• v.14 no.1
• /
• pp.30-41
• /
• 2006

Recently. the herbal industry has expanded into the herbal dietary supplements industry, the herbal cosmetics industry, etc. But still the main form of herbal drug usage is water extraction- packaging after herb preparation in private clinics. There was no report or data of investigations about industrial herbal preparations. To search for a better plan of herbal drug improvement and popularization. we surveyed the present state of Korean herbal preparation production. We made an industrial herbal preparation list, investigated the total amount of production, the chief items of manufacture. names of prescriptions each item is based on. scales of each production company, etc., and report on them on this article.

• Journal of Society of Preventive Korean Medicine
• /
• v.12 no.3
• /
• pp.9-20
• /
• 2008

The purpose of this study is to investigate the actual conditions of herbal medicine products for the establishment of drug utilization review system. To accomplish of the purpose, we investigated medical treatment pay of insurance and consumption of herbal medicine products in pharmacy at jeollabuk-do, two oriental hospital etc. To gain valid and reliable the actual conditions of herbal medicine products, it needed close relationship with oriental hospital, society for manufacture of herbal medicines etc and further study classify herbal medicines by Korean Medicine.

• Journal of Society of Preventive Korean Medicine
• /
• v.5 no.1
• /
• pp.57-75
• /
• 2001

This study was conducted to improve the current regulation guidelines for developing traditional Korean medicines with effectiveness and productivity, in order to cope with the upcoming ICH on specifications on oriental herbal drugs. Also, major purposes of this study are to motivate R&D and to pioneer foreign markets for domestic herbal drug companies. First, after examining concepts of traditional Korean medicines and comparing the numbers and differentiation of herbal drugs registered on Pharmacopeia among Korea, China, and Japan, the current new drug development requirements for traditional Korean medicines were reviewed in detail, followed by comparison of foreign regulation systems including USA, EU, China, and Japan. Second, empirical cases on failure of development for new traditional Korean medicines under the current regulation system in the domestic companies including Dong-A, Kwangdong, and Samchondang, were collected and analyzed. As a result, hanbangsaengyak, the new category for traditional Korean medicines was newly developed on the basis of scientification of data between saengyak and hanyak, from the perspectives of harmonization between oriental medicine and western medicine and of balance between food and drug, in terms of industrialization, publicity, modernization, and effectiveness of administration. In addition, the new regulation requirements for the new hanbangsaengyak preparations were discussed by establishing principles of reinforcing preclinical test and of simplifying clinical trials in Korea. Finally, the further researches to articulate the complete specifications for pre-clinical and clinical requirements for traditional Korean medicines were strongly suggested.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.34 no.2
• /
• pp.62-81
• /
• 2021

Objectives: The purpose of this study is to review clinical studies and evaluate effectiveness of intravaginal administration of oriental medicine on vaginal atrophy in menopausal women. Methods: 'postmenopause', 'menopause', 'vaginal atrophy', 'atrophic vaginitis', 'vaginal cream', 'vaginal gel', 'pessary', 'suppository' were searched on 3 online databases (Pubmed, Cochrane Library, OASIS). The risk of bias was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results: 9 randominized controlled trials (RCTs) were selected among 489 articles. The types of intervention were intravaginal administration of oriental medicine. 6 studies showed that treatment group was better than placebo control group or both treatment group and western medicine control group improved similarly. 2 studies were not significant effective in some results and 1 study was not statistically significant. Conclusions: Intravaginal administration of oriental medicine can be an effective option in treating menopausal women with vaginal atrophy. but considering the small number and low quality of studies, further well-designed studies are needed to confirm the effectiveness of this treatment.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2018.10a
• /
• pp.34-34
• /
• 2018

천연물 산업은 과학적 기술력이 요구되는 고부가가치 산업으로 건강기능식품 등의 원료 산업으로 각광받고 있다. 최근 친환경, 지속가능성에 대한 관심 증가로 천연물 제품에 대한 수요가 증가되고 있으며 고령화 사회 진입과 건강에 대한 의식 수준 상승으로 전세계 건강기능 식품 시장 확대 추세에 있다. 생물자원의 70%이상을 수입에 의존하고 있는 우리나라는 천연물 산업의 경쟁력 확보와 고부가가치화 실현을 위해 천연물 산업 육성 촉진이 필요하다. 또한 지역 균형발전 측면에서 신성장동력 마련 및 국가 차원의 형평성을 고려한 전략적 투자가 필요한 시점에서 천연물 관련 산업의 신성장동력화를 통해 지역의 한계점 등을 개선하고, 새로운 먹거리 발굴과 함께 지역 전략산업으로 육성이 필요하다. 제천의 특화산업업인 한방천연물산업의 고도화와 활성화를 위해 영세한 스타트업 및 중소기업의 연구 및 제품개발을 지원하기 위한 인프라와 산업 클러스터 조성이 요구되고 있다. 제천은 풍부한 한약재 생산지를 보유하고 있어 전체 면적의 50% 이상이 석회암 지대로 알칼리성 토양이 넓게 분포되어 있고, 토양의 양분이 풍부하며 해발고도 250m 이상의 준산간 지역에서 주로 재배가 이루어지고 있어, 배수가 양호하고 병충해가 적어 한약재의 친환경 재배 및 다년생 한약재 재배가 가능한 지역이다. 이러한 천연물 산업을 육성하기 위하여 산업통상자원부, 충청북도, 제천시, (재)충북테크노파크는 180억원의 사업비로 '글로벌 천연물 원료제조거점시설'을 구축하여 규격화된 천연물 원료공급 시스템을 갖추었으며 150억원을 투자하여 '천연물 조직배양 상용화 시설'을 건립 중에 있다. 또한 향후에는 천연물 클러스터 가치 사슬의 완성형으로 160억 상당의 '천연물 제제개발 생산시설' 사업을 기획하고 있어 장차 대한민국의 천연물 산업을 앞장서 견인할 것으로 예상 된다.

• Journal of Pharmacopuncture
• /
• v.1 no.1
• /
• pp.103-125
• /
• 1997

In order to study of safety, Hwanggum(黃芩) aqua-acupuncture was prepared by boiling extract and filtration. This study was performed to determine the toxic effects of graded dose levels and effects of Scutellaria Root after repeated administration(14days). From these results, Hwanggum(黃芩) aqua-acupuncture was quite sag in male and female rats.

• Journal of Korean Traditional Oncology
• /
• v.23 no.1
• /
• pp.23-32
• /
• 2018

Objective: The purpose of this study is to report the case of a patient with non-small cell lung adenocarcinoma (NSCLC) with anaplastic lymphoma kinase (ALK) mutation treated by Samchilchoongcho-Jung in conjunction with Crizotinib. Methods: An NSCLC patient diagnosed with multiple pleural and lymph nodes metastasis has been taking Crizotinib (500 mg/day) since January 2014. The patient has been treated with Samchilchoongcho-Jung (1,500 mg/day) since June 2014. The tumor size was measured by computed tomography (CT) and laboratory analysis was conducted. Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After combining treatment, stable disease was shown on CT. The tumor marker (CEA, Cyfra 21-1) levels were maintained. NCI-CTCAE 5.0 showed no adverse events. Conclusion: This case study suggests that Samchilchoongcho-Jung may contribute to tumor response, in conjunction with Crizotinib on the treatment of patients with NSCLC.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.25 no.6
• /
• pp.996-999
• /
• 2011

This experiment was performed to investigate whether the combined-preparation of crude drugs (The $Well^{TM}$ Preparation, TW), has hypnotic effects and/or enhances pentobarbital-induced sleep behaviors. TW was mixed with water extracts of Ginseng Radix red, Germinated brown rice, cultured mountain ginseng, and 50% ethanol extracts of Longanae Arillus, Nelumbinis Folium and Chrysanthemi Flos. TW (100 mg/kg, p.o.) reduced sleep onset and prolonged sleep time induced by pentobarbital similar to muscimol (0.2 ${\mu}M$), a $GABA_A$ receptor agonist. Also, TW (2 ${\mu}g$/ml) and pentobarbital (2.5 ${\mu}M$) did not affect the chloride influx in primary cultured cerebellar granule cells, respectively, but the combined-treatment of TW (2 ${\mu}g$/ml) and pentobarbital (2.5 ${\mu}M$) increased the chloride influx onto the cells. In conclusion, TW augments pentobarbital-induced sleep behaviors; these effects may result from chloride channel activation.