• Journal of the Korean Society of Food Culture
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• v.24 no.1
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• pp.77-83
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• 2009

This study was conducted to investigate the chemical composition and biological function of tea made from mountain-cultivated ginseng leaves. The antioxidant activities of tea made from mountain-cultivated ginseng leaves were determined by measuring their electron-donating ability based on their DPPH and nitrite-scavenging ability. The electron-donating abilities of tea made from mountain-cultivated ginseng leaves (500 and 1,000 ppm) as determined by DPPH assay were 45.6 and 85.1%, respectively. The nitrite scavenging ability of tea made from mountain-cultivated ginseng leaves (500 and 1,000 ppm) at pH 6.0 were 32.8 and 51.4%, respectively. Furthermore, the nitrite scavenging activity increased in a dose-dependent manner at all pH values. The effects of tea made from mountain-cultivated ginseng leaves on Male Sprague-Dawley rats were also evaluated. To accomplish this, the rats were divided into three groups (A: normal diet group, B: high fat diet group and C: high fat diet supplemented with tea made from mountain-cultivated ginseng leaves group). The anti-obesity effects of tea made from mountain-cultivated ginseng leaves were then evaluated. The serum total lipid, total cholesterol and triglyceride contents in C group were lower than those of B group; however, these differences were not statistically significant. The HDL-cholesterol content was significantly higher in the C group than in the other groups. Taken together the results of this study suggest that tea made from mountain-cultivated ginseng leaves possesses antioxidant activity and improves lipid metabolism.

• Journal of the Korean Society of Food Culture
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• v.23 no.2
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• pp.222-227
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• 2008

This study examined the chemical composition of lotus root and functionally evaluated a fermented lotus root drink. Electron-donating ability using DPPH along with nitrite-scavenging ability were used to compare the antioxidative activities of unfermented and fermented lotus root drinks. The electron-donating abilities of the unfermented lotus root drink (1%) and fermented lotusroot drink (1%) were 22.55% and 23.88%, respectively. At pH 6.0, the nitrite-scavenging abilities of the unfermented lotus root drink and the fermented lotus root drink (100%) were 27.64% and 40.3%, respectively, and their scavenging ability increased in a dose-dependent manner at all pH values. In order to study the anti-obesity effects of the two drinks, male Sprague-Dawley rats were divided into four groups (A: basal diet, B: high fat diet, C: high fat diet+unfermented lotus root drink, D: high fat diet+fermented lotus root drink). Net weight gains were not significantly different among the four groups. Plasma total cholesterol concentrations significantly decreased in the groups receiving the unfermented and fermented lotus root drinks. Also, plasma total lipid and triglyceride contents were lower in the groups receiving the unfermented and fermented lotus root drinks as compared to the high fat diet group; however, the differences among the three groups were not significant.

• The Korean Journal of Pesticide Science
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• v.16 no.1
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• pp.28-34
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• 2012

We analysed 149 samples of Korean traditional herbal tea materials. The 156 pesticides were analyzed by GC/ECD and NPD, detected pesticides were confirmed by GC-TOF/MS. Sample preparation was performed bv multi-residue analysis method of multiclass pesticides of the Korea Food Code. The residual pesticides were detected in 22 samples(14.8%), the highest detection frequency samples are lycium and jujube. Detected pesticides in Korean traditional herbal tea materials were chlorpyrifos (5 samples), chlorothalonil (3 samples), cypermethrin (3 samples), hexaconazol (3 samples) and cyhalothrin(3 samples). The pesticide types detected in Korean traditional herbal tea materials were organophosphorus(29.2%), pyrethroids(16.7%), organochlorines (12.5%) and triazoles(12.5%). The 5 samples(lycium, jujube, chrysanthemum, balloon-flower, milk vetch root) were detected pesticides below MRLs, 2 samples(cornus fruit, cnidium) were detected pesticides unnotificated MRLs.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.1
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• pp.97-106
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• 2007

Objectives : The purpose of this study was to investigate the clinical effect of oriental medical short term therapy on visceral fat obesity. In present study, we report 20-year-old visceral fat obesity woman who experienced oriental medical therapy program. Methods : The obese patient was treated from the 20th of June to the 3rd July. Herbal medicine, low calorie diet, electrolipolysis, auricular acupuncture, and aerobic exercise were done during the treatment period. Results : Her body weight decreased from 77.30kg to 71.15kg. The BMI decreased from $32.6kg/m^2$ to $29.5kg/m^2$. First of all, visceral fat tissue was effectively decreased after oriental obesity therapy evaluated by CT. Visceral fat tissue decreased from $123.44cm^2$ to $83.06cm^2$, subcutaneous fat tissue from $327.88cm^2$ to $323.09cm^2$. Short term oriental medical treatment could be effective in visceral fat obesity treatment. Conclusions : The patient with visceral fat obesity was improved using short term oriental medical treatment.

• The Journal of Internal Korean Medicine
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• v.40 no.1
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• pp.38-57
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• 2019

Objective: This study reviewed recent clinical research trends regarding the effects of herbal medicine treatment containing diuretic herbs on nonalcoholic fatty liver disease (NAFLD) in China. Methods: We reviewed clinical studies on NAFLD from the China Academic Journal of the China National Knowledge Infrastructure from January 1, 2016, to September 10, 2018. Results: Thirty-nine papers from 86 studies were reviewed. The most commonly used herbal prescriptions included Alismatis Rhizoma(澤瀉), Salviae miltiorrhizae Radix (丹蔘), Crataegii Fructus (山査), Polia Sclerotium (茯?), Bupleuri Radix (柴胡), and Cassiae Semen (決明子). The treatment effective rate, liver function test, serum lipid test, radiological examination, and symptom comparisons were used to analyze the treatments. In 32 of the papers, the effective treatment rate was 76.9%-100%, and the effectiveness in the experimental group was significantly higher than that in the control group (p<0.05). The risk ratio for the treatment effective rate was 1.26. The mean difference of ALT was -13.44 U/L (95% confidential interval, -24.45 U/L, -2.44 U/L, p=0.0166). Conclusion: Herbal medicine containing diuretic herbs has been demonstrated to be an effective and useful treatment for NAFLD. Clinical studies that are more scientific and systematic should be actively conducted in the future, and the results of the current study could be used as basic data in future clinical studies on herbal medicine treatment for NAFLD.

• The Journal of Korean Obstetrics and Gynecology
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• v.35 no.3
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• pp.1-23
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• 2022

Objectives: The purpose of this study is to evaluate anti-breast cancer and anti-inflammatory effects of Chungganhaewool-tang and Shipyeukmiyeugi-eum. Methods: MDA-MB-231 cells were used to measure cytotoxicity, Reactive oxygen species (ROS) production, protein expression amounts of Bcl-2-associated X protein (Bax), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), Cytochrome C Caspase-3, Caspase-7, Caspase-9, Poly ADP-ribose polymerase (PARP), Nuclear factor erythroid-2-related factor 2 (Nrf2), Heme oxygenase-1 (HO-1) and NAD (P) H Quinone Oxidoreductase 1 (NQO1) to evaluate the anti-breast cancer effects of Chungganhaewool-tang (CHT) and Shipyeukmiyeugi-eum (SYE), and THP-1 cells, differentiated into macrophage and induced inflammation with Lipopolysaccharide (LPS), were used to measure production amounts of ROS, Nitric oxide (NO), and protein expression amounts of Inducible nitric oxide synthase (iNOS), Cyclooxygenase (COX-2), Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6) and Tumor necrosis factor-alpha (TNF-α) to evaluate the anti-inflammatory effects of CHT and SYE. Results: CHT and SYE reduced MDA-MB-231 cell counts, increased protein expression of Bax and Cytochrome C, and decreased protein expression of Bcl-2, Bcl-xl. The protein expression amounts of Caspase-3, 7, and 9 decreased, but amounts of the active form, cleaved Caspase-3, 7, and 9, increased. In addition, PARP protein expression decreased, the amount of PARP protein in the cleaved form increased, and the amount of protein expressions of Nrf2 and HO-1 decreased, but NQO1 showed no significant difference. In THP-1 cells CHT and SYE reduced ROS and NO, and reduced protein expressions of iNOS, COX-2, IL-1, and TNF-α, but only SYE groups reduced IL-6. Conclusions: This study suggests that CHT and SYE have potential to be used as treatments for breast cancer.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.4
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• pp.172-180
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• 2022

Objectives : This study reports a 61-year-old man with sudden hearing loss and tinnitus whose symptoms improved remarkably after treatment with Korean medicine. Methods : The patient was treated with herbal medicine(gamisoyo-san, samul-tang gagambang, gongjindan, and yukmijihwang-hwan), acupuncture and moxibustion. Puretone audiometry(PTA), speech audiometry(SA), Korean tinnitus handicap inventory(K-THI), patient self-report, numeric rating scale(NRS) 11, and review of system(ROS) were performed. Results : After a month of treatment, PTA was improved from profound to mild and audiometric findings were improved in speech reception threshold and word recognition score. After 2 months of treatment, K-THI decreased from 92 to 28 and NRS 11 score decreased more than 6 in every item. Conclusions : These results demonstrate that Korean medicine could be effective sudden hearing loss and tinnitus.

• Korean Journal of Plant Tissue Culture
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• v.21 no.2
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• pp.65-68
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• 1994

Plant regeneration from the stem tissue of Orostachys japonicus A. Beiger was investigated. The calli derived from shoot apex when apex when cultured on Murashige and Skoog (MS) medium supplemented with 4mg/L 2,4-dichlorophenoxyacetic acid (2,4-D)and 2 mg/L benzyl aminopurine (BAP). The calli were developed into shoot to MS medium with 0.5mg/L NAA and 2mg/L and into root with 1mg/L kinetin. The reddish pigment which might be essential for the rootregeneration was observed in the tip of regenerated root.

• 대한한약신문
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• s.118
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• pp.1-8
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• 2007

백년사출판기념회.제50회 정기총회 개최/외국인 정부차원 무료 한방진료사업 시행/보건의료학생모임, "한미FTA 반대"/복지부, 공중보건한의사 96명 추가 모집/담배의 폐해! 이젠 담뱃갑에서도 확인/삼척의료원 한.양방 공동진료/공중보건한의사 수급관련 보건복지부 입장 밝혀/서울, 제82회 정기총회 개최/인천, 제27회 정기총회 개최/전북, 제50회 정기총회 개최/강원, 제47회 정기총회.연수교육 실시/지부탐방-지부장에게 듣는다/칼럼-계절에 맞는 음식/명칭이 비슷하여 감별하기 어려운 한약재/비증 이야기/인진(호)에 대한 소고

• 건강소식
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• v.32 no.2 s.351
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• pp.18-19
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• 2008

마늘과 감초. 둘 다 약성이 뛰어난 식품이다. 마늘은 항암 식품의 대표격으로, 중국에서 최근 실시된 역학조사 결과에 따르면 연간 1.5㎏씩 마늘을 먹는 사람이 암에 걸릴 위험은 거의 안 먹는 사람에 비해 50%나 낮았다. 정자의 수를 늘리고 발기를 돕는다는 동물 실험 결과도 있다. 혈액순환을 돕고 혈압을 내려주는 효과도 있다. 감초는 '약방에 감초' 라는 말이 있을 정도로 한약재에 두루 쓰이는 약초다. 한방에선 대개 여러 약 성분을 조화시키고약의독성을완화시키기위해사용한다.