• Journal of Oral Medicine and Pain
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• v.31 no.1
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• pp.47-57
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• 2006

The purpose of this study was to assess the effects of the superficial heat therapy on the cutaneous blood flow and the skin temperature at pre-auricular region. Two types of the superficial heat therapy-moist hot pack & infrared lamp- were applied to 20 healthy subjects(male: 10, female: 10). For each subject, the two parameters of cutaneous blood flow and skin temperature were measured before and after heat therapy, using laser doppler flowmetry(LDF). The author analyzed the differences of the effects between the two therapies and also characteristics of responsiveness between the two parameters. The results were as follows : 1. The two parameters were significantly increased after both superficial heat therapies. 2. Skin temperature showed a maximum peak immediately after both superficial heat therapies, but cutaneous blood flow showed a maximum peak 4 minutes after both superficial heat therapies. 3. Increased cutaneous blood flow after application of moist hot pack lasted longer than infrared lamp. 4. Increased skin temperature after both superficial heat therapies lasted for 60 minutes, but increased skin temperature after infrared lamp decreased more rapidly than moist hot pack. 5. Amount of changes in cutaneous blood flow after infrared lamp was larger in female than in male, but no significant gender difference was found since 20 minutes after infrared lamp. Both moist hot pack and infrared lamp showed favorable effectiveness in raising cutaneous blood flow and skin temperature. Moist hot pack was slightly superior in maintaining this effect.

• The Journal of Korean Society for Radiation Therapy
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• v.18 no.1
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• pp.21-28
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• 2006

Purpose: The purpose of this study is to find a optimal beam spoiler condition on the dose distribution near the surface, when treating a squamous cell carcinoma of the head and neck and a lymphatic region with 10 MV photon beam. The use of a optimal spoiler allows elivering high dose to a superficial tumor volume, while maintaining the skin-sparing effect in the area between the surface to the depth of 0.4 cm. Materials and Methods: The lucite beam spoiler, which were a tissue equivalent, were made and placed between the surface and the photon collimators of linear accelerator. The surface-dose, the dose at the depth of 0.4 cm, and the maximum dose at the dmax were measured with a parallel-plate ionization chamber for $5{\times}5cm\;to\;30{\times}30cm^2$ field sizes using lucite spoilers with different thicknesses at varying skin-to-spoiler separation (SSS). In the same condition, the dose was measured with bolus and compared with beam spoiler. Results: The spoiler increased the surface and build-up dose and shifted the depth of maximum dose toward the surface. With a 10 MV x-ray beam and a optimal beam spoiler when treating a patient, a similer build-up dose with a 6 MV photon beam could be achieved, while maintaining a certain amount of skin spring. But it was provided higher surface dose under SSS of less than 5 cm, the spoiler thickness of more than 1.8 cm or more, and larger field size than $20{\times}20cm^2$ provided higher surface dose like bolus and obliterated the spin-sparing effect. the effects of the beam spoiler on beam profile was reduced with increasing depths. Conclusion: The lucite spoiler allowed using of a 10 MV photon beam for the radiation treatment of head and neck caner by yielding secondary scattered electron on the surface. The dose at superficial depth was increased and the depth of maximum dose was moved to near the skin surface. Spoiling the 10 MV x-ray beam resulted in treatment plans that maintained dose homogeneity without the consequence of increased skin reaction or treat volume underdose for regions near the skin surface. In this, the optimal spoiler thickeness of 1.2 cm and 1.8 cm were found at SSS of 7 cm for $10{\times}10cm^2$ field. The surface doses were measured 60% and 64% respectively. In addition, It showed so optimal that 94% and 94% at the depth of 0.4 cm and dmax respectively.

• Journal of the East Asian Society of Dietary Life
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• v.19 no.5
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• pp.750-760
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• 2009

In this study, the various effects of Salicornia herbacea, including antioxidative function, antibiotic, and anti-inflammatory effect, and the effect of sebiparous reduction due to intervention of the DHT hormone were investigated using. The result of this study Based on this analysis, the serum total cholesterol, triglyceride, and WBC were found to be significantly decreased and SOD, Ca, K, and Zn were shown to be significantly increased significantly in the group that received the SH pill group after trial fora 12 week trials. Testosterone and DHT were increased in the SH pill group, but it was not statistically significant. In the case of the skin condition measurements, the number of blackhead pores, skin oiliness, keratin and, MIC were significantly decreased, and the pH was decreased to normal pH in the SH pill group. Therefore, it was confirmed that overall skin condition was improved due to Salicornia herbacea diet. The results of this research result can contribute so demonstrate the potential of actively using that the Salicornia herbacea can be actively developed as a health supplement, and a medication.

• 건강소식
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• v.34 no.11
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• pp.16-17
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• 2010

무더위에, 하루가 멀다 내리던 비가 며칠 전에도 내렸던 것 같은데, 창밖을 보니 어느새 나뭇잎들이 곱게 물들고 있다. 이런 계절의 변화를 우리 몸에서 가장먼저 알아차리는 곳 중에 하나가 피부이다. 여름에서 가을로 접어들면 기온이 떨어지고 습도가 떨어지는데, 우리 몸의 최외곽 방어를 담당하는 피부는 이런 변화에 예민하게 반응한다. 아침에 세안을 하고 나서 잠시 다른 일을 하느라 로션 바르는 것이 조금 늦어지면, 하얗게 일어나고 있는 각질을 쉽게 볼 수 있다. 가을에 더더욱 그러하다.

• 건강소식
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• v.37 no.1
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• pp.24-26
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• 2013

건선은 신체 면역체계에 이상이 생겨 피부에 염증 반응을 일으키는 질병으로 평소 건강관리를 소홀히 해 면역력이 약해지면 나타나기 쉽다. 보통 바르는 연고로 치료하지만 심할 경우 자외선 치료와 함께 고가의 면역 억제 주사가 필요한 악성 질환이다. 원인과 동반질환, 효과적인 예방법을 알아보았다.

• Journal of Korea Society of Industrial Information Systems
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• v.20 no.3
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• pp.11-18
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• 2015

Stress is one of the major causes threatening the mental and physical health of human today. In this paper, we analyzed the heart rate variability(HRV), galvanic skin response(GSR), and skin temperature data measured from the university subjects before and after the class to examine the influence on bio-signal in stress environment. Thirty subjects from university students (aged between 21 and 27 years; mean=22.31, STD=1.45) took part in this study. From the experiment results, RMSSD(p=0.033), LF peak(p=0.003), VLF(p=0.045) were statistically significant from those of the control group(p<0.05) of HRV both in time and frequency domain. We observed that mean skin conductivity after the class(mean=5.993(uS), SD=3.406) is higher than that before the class(mean=3.039(uS), SD=2.628) by 97.2% on average and the skin temperature after the class($34.835{\pm}0.305$) is slightly higher than that before the class($34.471{\pm}0.281$) by 1.055% on average. The results in this research could be used to examine the autonomic response in clinical stress related research.

• Journal of Life Science
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• v.19 no.3
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• pp.327-333
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• 2009

Psoriasis is a well known disorder of keratinization. In this disease, several reports revealed that dermal micro vessels are increased and angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are over-expressed. Angiogenesis may play an important role in the progression of psoriasis. Acitretin is widely used as an anti-psoriatic drug because of its potent action on keratinocyte growth and differentiation, but its effects on angiogenesis are uncertain. The goal of this immunohistochemical study was to investigate the effects of acitretin on the expression of VEGF in psoriatic lesions of the skin. We compared the expression levels of VEGF between pre- and post-acitretin treated skin - 10 psoriatic skin lesions and 3 normal (control) skins. The expressions of VEGF in psoriatic skin lesions were significantly higher than in normal control skin. The expressions of VEGF in psoriatic skin lesions post-treatment were lower than those pre-treatment. Acitretin revealed inhibitory effects on angiogenesis by reducing the expression of angiogenic factors such as VEGF in psoriatic skin lesions. We suggest that acitretin may be useful in therapeutic approaches to psoriasis management, possibly related to angiogenesis.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2021.04a
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• pp.4-4
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• 2021

전 세계는 covid 19의 pandemic 상황이 장기화되면서 화장품 분야의 trend 변화가 일어나고 있다. covid 19의 예방으로 마스크는 생활필수품이 되었고, 행정적으로도 사무공간에서도 마스크를 착용하지 않으면 과태료를 부과하는 상황에 이르렀다. 이로 인하여 장시간 마스크 착용은 필수 불가결한 상황이며, 이로 인하여 얼굴 피부의 장벽기능(barrier function)의 와해로 인하여 피부가 예민해지고 크고 작은 피부의 trouble이 많이 발생하고 있다. 이에 따라 소비자들은 화장품의 선택에 있어 피부 진정과 피부에 자극완화(anti-irritation) 및 안전성(safety)에 대한 것으로 점차적으로 변화하고 있다. Covid 19 이전의 화장품 소재 및 제품 개발의 트렌드는 국내의 기능성화장품 범주에 있는 미백 관련, 주름관련, 자외선 차단관련, 염모관련, 육모 탈모 관련, 여드름관련, 피부장벽관련, 튼살 관련 기능성 소재 및 제품 개발과 화장품 용도외의 고기능성 부여를 위한 코스메슈티컬(cosmeceutical)용 제품의 개발이 중요한 시기였다. 코스메슈티컬(cosmeceutical)은 화장품(cosmetic)과 의약품(pharmaceutical)의 합성어이다. 그러나 최근 Covid 19의 상황에 따라 화장품 업계는 포스트 코로나의 트렌드로 피부 장벽기능 강화, 피부노화 억제, 식물성, 자극완화, 비건, 안전성 확보에 대한 다양한 천연 소재의 연구와 제품을 개발 출시하고 있다. 따라서, 2020년 Covid 19의 상황에 따른 화장품 분야의 천연 신소재 및 화장품 개발 방향에 대하여 자원 식물의 활용성 및 개발 동향에 대하여 논의 하고자한다.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2014.06a
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• pp.71-72
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• 2014

최근 들어 드라마나 영화 속 인물 들의 얼굴을 다른 얼굴로 교체하고자 하는 시도들이 주목을 받고 있고, 사용자들의 관심 또한 증가하고 있다. 이러한 연구는 오래 전부터 많이 연구되어 왔으나, 조명 변화에 강인한 피부 톤 변환 문제는 여전히 주요 이슈로 자리하고 있다. 본 논문에서는 히스토그램 명세화 기법을 응용하여 피부 톤을 자연스럽게 변환 시켜줄 수 있는 기법을 제안한다. 두 얼굴 영상의 R, G, B 채널에 대한 히스토그램을 각각 생성하고 이들을 누적분포함수로 각각 변환한다. 변환된 누적분포함수들을 이용하여 두 얼굴 영상의 히스토그램을 근사 시킬 수 있는 변환 표를 생성하고 이를 이용하여 얼굴 영상의 피부 톤을 변환시킨다. 조명 변화로 인해 발생하는 전반사 영역은 선형 보간 법을 사용하여 제거한다. 실험 결과, 제안하는 방법이 조명 변화에 적응적으로 대처하면서 자연스럽게 피부 톤을 변환 시켜줄 수 있음을 확인하였다.

• Journal of the Korea Society of Computer and Information
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• v.26 no.12
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• pp.237-245
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• 2021

This study investigated the Antimicrobial activity of Rutaceae fruit ethanol extracts against microorganisms-induced skin inflammation in cosmetic materials. Rutaceae fruits were separated in two parts of whole fruit (pulp, pulp fegment membrane, peel) and peel, and extracted with 70% ehtanol. The results demonstrated that Rutaceae fruit ethanol extracts showed antimicrobial activity in 5 strains except Staphylococcus aureus. In particular, the antimicrobial activity against Staphylococcus epidermidis was the best in fresh lemons whole fruit. The antimicrobial activity against Escherichia coli was shown only in fresh lemon peel and fresh trifoliate peel. Additionally, antimicrobial activity against Propionibacterium acnes was shown only in the dried lemon peel. In the results of antimicrobial activity against Pityrosporum ovale, in the case of fresh fruits, citron whole fruits showed the highest effect, followed by lemon whole fruits and mandarin orange peel. And in the case of dried fruits, orange peel showed the highest effect, followed by trifoliate peel, mandarin orange peel and lemon peel. Therefore, it is considered that lemon, which shows antimicrobial activity against all skin inflammation-causing microorganisms, can be used as a natural material for improving skin inflammation in cosmetics.