• Title/Summary/Keyword: 피부 반사도

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A CASE OF PRADER-WILLI SYNDROME TREATED WITH FLUOXETINE (Prader-Willi 증후군의 Fluoxetine 치험 1례)

  • Shin, Dong-Won;Song, Dong-Ho
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.8 no.1
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    • pp.133-138
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    • 1997
  • Prader Willi Syndrome(PWS) was first recognized and reported by Prader-Willi. The etiology of the syndrome is not fully understood, but 50-70% of the patients show small deletion in chromosome 15. Manifested symtoms vary according to developmental age. In early life, hypotonia, areflexia, feeding difficulties, hypothermia, microgenitalia, hypoplastic scrotum, cryptochordism were observed. But in several years, hypotonia disappears, and polyphagia, decreased satiety, psychomotor retardation, obesity, hypogonadism and short stature become main problems. Behavioural problems including temper and aggressive outbursts, stealing food, hoarding food, and self excoriating skin picking, trichotillomania are more prominent during adolescence and young adulthood. Also, irritable, depressed mood are described. Lots of psychological and behavioural problems explain the reason why psychiatrists have managed and reported this syndrome. However, there has been no official report of PWS in our country. So authors report the clinical characteristics and issues in management of a patient with PWS.

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Study of Microwave Propagation Characteristics of Matching Liquids for the Microwave Cancer Detection System (유방암 진단 시스템을 위한 정합 액체의 전파 특성에 관한 연구)

  • Kim, Jang-Yeol;Minz, Laxmikant;Lee, Kwang-Jae;Son, Seong-Ho;Jeon, Soon-Ik
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.25 no.4
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    • pp.442-450
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    • 2014
  • This paper is a study of the propagation characteristic of matching liquids in the skin-covered breast model. In order to evaluate the matching liquids, we investigated six kinds of matching liquids applied to proposed 1-D breast model from frequency range of 3~6 GHz. A uniform plane wave is projected / transmitted inside the multi-layered breast model. Then the propagation characteristics inside the model and the transmission loss of each matching liquids were analyzed. The studying method presented in the paper can be used in the breast cancer detection system, the field of cancer detection using human tissue and the field of other medical devices. This paper was applied to the breast cancer detection system. Consequently, these studies could be used to determine the suitable type of matching liquids for breast cancer detection system and to apply useful for performance analysis.

Synthesis and Property of Titanium Dioxide Nanosol with a High Crystalline Characteristics (고결정성을 갖는 이산화티탄 나노 졸의 합성 및 특성)

  • Sim, Jae-Kyung;Park, Jong-Kwon;Cho, Jung-Eun;Jeong, Noh-Hee
    • Applied Chemistry for Engineering
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    • v.30 no.6
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    • pp.694-697
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    • 2019
  • In recent years, titanium dioxide powders were produced as nanoparticles or nanowires or nanotubes in one-dimensional structure, and mesoporous spheres in 3-D to improve their crystallinities, which were further used as photo-electrode materials and for preventing photo-aging. In this study, a nano sol composed of titanium dioxide exhibiting a high crystallinity was synthesized using n-alcohol as a solvent. The crystallinity of the nano sol was confirmed by FE-SEM, and XRD, while the UV blocking rate confirmed by UV-Vis spectrometry results. Changes in the crystallinity were investigated by varying the types of solvents such as butanol, propanol and ethanol. The synthesized particle sizes were from 200 to 250 nm, and the optical transmittance showed a high blocking rate in the UVB and UVA range. It is expected that a high transmittance at 550 nm wavelength can increase the photoelectric conversion efficiency of solar cells and the UV blocking efficiency.

Feasibility Study for the Development of a Device for Pathological Tissue (병리학적 조직 진단장치 개발에 대한 타당성 분석 연구)

  • Ko Chea-Ok;Park Min-Young;Kim Jeong-Lan;Lee Ae-Kyoung;Choi Hyung-Do;Choi Jae-Ic;Pack Jeong-Ki
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.17 no.4 s.107
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    • pp.341-350
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    • 2006
  • In this paper, a new method for detecting breast cancer is proposed, which utilizes dielectric characteristics of pathological tissues and time delay of back scattered response, and its feasibility was investigated. We have developed a detection algorithm and verified it by numerical simulation and measurement for a prototype system. For a prototype system, we have fabricated experimental model(artificial breast with a cancer) and UWB(ultra-wideband) antenna. The results of the measurement simulation show an excellent detection capability of a cancer tissue. It is found that a good UWB antenna and a good calibration signal are key elements of such detection system. Further study is ongoing to develop a commercial system.

The Effect of Hand Reflexology on Pain, Skin Temperature and Nursing Practice (입원 환자에서 손 반사요법의 통증, 피부체온 및 간호실무 효과)

  • Ha, Hyae-Chung;Lee, Young-Soon;Kim, Dong-Soo;Lee, Myung-Sook;Oh, Sei-Young
    • The Journal of Korean Academic Society of Nursing Education
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    • v.12 no.2
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    • pp.178-186
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    • 2006
  • Purpose: This study is aimed to examine the effectiveness on pain, feeling and nursing practice of hand reflexology applied to in-patient in the clinical setting. Method: The pre/post test methods using VAS for pain and feeling, physiologic measuring, and questionnaire of nursing care were conducted. Subjects were selected 45 in-patients from a surgical ward in hospitals during Nov.-Dec. 2005. 5 minute hand reflexology therapy was applied to both hands of participant by two research assistants at the same time. Data were analyzed based on SAS program using frequency, $x^2$-test, paired t-test, ANOVA and Pearson's correlation coefficients. Result: 1. After receiving hand reflexology therapy, the subjects showed significant pain relief(t=-4.94, p=.0001), improvement in feeling(t=19.44, p=0001) and an increase in skin temperature(t=3.54, p=.001). 2. The applied skills that the participants preferred were press-rotate(80.0%), press-walk(35.56%) and press-rolling(31.11%). The effectiveness of nursing practice scored $3.99{\pm}1.97$ out of 5. Nurse-Patient Relationship and effective response of nursing intervention ranked the highest 4.31. Conclusion: Hand reflexology was considered as an effective nursing intervention in the clinical settings, but in order to evaluate re-verifies and reliances for this effects, it is necessary that comparative studies should be conducted.

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Non-invasive Blood Glucose Detection Sensor System Based on Near-Infrared Spectroscopy (근적외선 분광법 기반 비침습식 혈당 검출 센서 시스템)

  • Kang, Young-Man;Han, Soon-Hee
    • The Journal of the Korea institute of electronic communication sciences
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    • v.16 no.5
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    • pp.991-1000
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    • 2021
  • Among non-invasive blood glucose detection technologies, the optical technique is a method that uses light reflection, absorption, and scattering characteristics when passing through a biological medium. It reduces pain or discomfort in measurement and has no risk of infection. So it is becoming a major flow of blood glucose detection research. Among them, near-infrared spectroscopy has a disadvantage in that the complexity increases when analyzing signals detected due to interferences between proteins and acids that share a similar absorption function with blood glucose molecules. In this study, a non-invasive sensor system with multiple near-infrared bands was designed and manufactured to alleviate the deterioration of blood glucose detection function that may occur due to skin absorption of near-infrared rays. A blood survey was conducted to verify the system, and the degree of blood glucose response in the blood was collected as spectral data, and the results of this study were quantitatively verified in terms of correlation between the data and blood glucose.

Intestinal Ultrasonographic and Endoscopic Findings in Pediatric Patients with Henoch-Sch$\"{o}$nlein Purpura and Gastrointestinal Symptoms (위장관 증상을 동반한 Henoch-Sch$\"{o}$nlein Purpura 환아의 장관 초음파 소견 및 내시경 소견)

  • Noh, Yun-Il;Ryu, Min-Hyuk;Jung, Chul-Zoo;Lee, Dong-Jin;Kwon, Jung-Hyeok
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.4 no.2
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    • pp.181-190
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    • 2001
  • Purpose: The aim of this study is to investigate the usefulness of intestinal ultrasonography (US) and upper gastrointestinal endoscopy in the early diagnosis of Henoch-Sch$\"{o}$nlein purpura (HSP) with the gastrointestinal (GI) symptoms preceding the emergence of the skin lesion. Methods: The clinical, intestinal US and upper gastrointestinal endoscopic records of 85 patients (88 cases) with GI symptoms relating to HSP presenting between January 1999 and April 2001 were reviewed. Results: 1) GI symptoms were observed in 52 cases (59%) and skin, joint, renal and scrotal manifestations were observed in 88 (100%), 64 (73%), 15 (17%), 3 cases (3%) respectively. 2) Out of 52 cases with GI symptoms, abdominal pain was observed in all cases (100%). Positive stool occult blood, nausea and vomiting, abdominal tenderness, melena or tarry stool, diarrhea, hematemesis, rebound tenderness and rigidity were observed in 28 (50%), 17 (33%), 17 (33%), 12 (23%), 6 (12%), 4 (8%), 1 (2%) and 1 case (2%) respectively in order of frequency. 3) Intestinal US examination was performed in 27 cases with HSP and GI symptoms (52 cases). Out of 27 sonographic examinations 22 showed abnormal findings. Thickening of the duodeno-jejunal wall was observed in 16 cases (73%). Free peritoneal fluid, enlarged mesenteric lymph node, ileus and abnormal gall bladder were seen in 8 (36%), 8 (36%), 4 (18%) and 1 case (5%) respectively. In three cases of HSP without GI symptoms, those changes were absent. 4) In all of five cases with HSP and GI symptoms, endoscopic study showed mucosal edema and multiple hemorrhagic erosions especially at the second portion of the duodenum. Biopsy specimens from the duodenum of 2 cases out of 5 endoscopic examinations showed acute inflammatory infiltrates in the mucosa with hemorrhage. 5) Both intestinal US and endoscopic studies were performed in 4 cases with HSP and GI symptoms simultaneously. Out of 4 those cases, 3 cases showed the thickened duodeno-jejunal wall on the intestinal US, which suggested erosive hemorrhagic duodenitis by endoscopic findings. Conclusion: The typical but nonpathognomonic intestinal US findings including the thickening of the duodeno-jejunal wall and upper gastrointestinal endoscopic findings including hemorrhagicerosive duodenitis, in children with GI symptoms, should be considered a manifestation of HSP, even in the absence of skin lesion.

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Evaluation of Difference between Skin Motion and Tumor Motion for Respiration Gated Radiotherapy (호흡조절방사선치료를 위한 피부움직임과 종양움직임 차이 평가)

  • Kwon, Kyung-Tae;Lim, Sang-Wook;Park, Sung-Ho;Kwon, Soo-Il;Shin, Sung-Soo;Lee, Sang-Wook;Ahn, Seung-Do;Kim, Jong-Hoon;Choi, Eun-Kyung
    • Progress in Medical Physics
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    • v.19 no.1
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    • pp.14-20
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    • 2008
  • Accounting for tumor motion in treatment planning and delivery is one of the most recent and significant challenges facing radiotherapy. The purpose of this study was to investigate the correlation and clarified the relationship between the motion of an external marker using the Real-Time Position Management (RPM) System and an internal organ motion signal obtained fluoroscope. We enrolled 10 patients with locally advanced lung cancer and liver cancer, retrospectively. The external marker was a plastic box, which is part of the RPM used to track the patient's respiration. We investigated the quantitatively correlation between the motions of an external marker with RPM and internal motion with fluoroscope. The internal fiducial motion is predominant in the caraniocaudal direction, with a range of $1.3{\sim}3.5cm$ with fluoroscopic unit. The external fiducial motion is predominant in the caraniocaudal direction, with a range of $0.43{\sim}2.19cm$ with RPM gating. The two measurements ratio is from 1.31 to 5.56. When the regularization guided standard deviation is from 0.08 to 0.87, mean 0.204 cm, except only for patients #3 separated by a mean 0.13 cm, maximum of 0.23 cm. This result is a good correlation between internal tumor motion imaged by fluoroscopic unit and external marker motion with RPM during expiration within 0.23 cm. We have demonstrated that gating may be best performed but special attention should be paid to gating for patients whose fiducials do not move in synchrony, because targeting on the correct phase difference alone would not guarantee that the entire tumor volume is within the treatment field.

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Comparative Study of Subjective Mental Workload Assessment Techniques for the Evaluation of ITS-oriented Human-Machine Interface Systems (지능형 교통체계 기반 인간-기계 인터페이스 시스템 평가를 위한 정신적부하 측정방법의 비교 연구)

  • Cha, Doo-Won;Park, Peom
    • Journal of Korean Society of Transportation
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    • v.19 no.3
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    • pp.45-58
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    • 2001
  • Subjective mental workload assessment technique becomes a standard human factors and human-machine interface evaluation tool for the evaluation of ITS(Intelligent Transport Systems)-oriented information systems as well as the drivers visual activity analysis, physiological indices(GSR, EEG, ECG, etc.), secondary task performance, reaction time. vehicle control parameters(speed, steering behavior, accelerator control) that are widely applied for transportation and vehicle systems to evaluate the safety, to decide the system or design alternatives, and to establish the design guidelines. This paper reviewed and compared the most globally employed four mental workload assessment techniques that have been designed for the use of various human-machine systems and ITS-oriented in-vehicle information systems. NASA-TLX(National Aeronautics and Space Administration-Task Load Index). SWAT(Subjective Workload Assessment Technique), MCH(Modified Cooper-Harper) scale, and recently developed RNASA-TLX(Revision of NASA-TH) were compared in terms of sensitivity and subjective evaluations to derive the human-machine interface evaluation guidelines for the application of ITS-oriented in-vehicle information systems. Then, experiment results supported that RNASA-TLX is the prospective tool for the mental workload assessment of ITS-oriented in-vehicle information systems.

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Preparation of Porous PMMA/TiO2 Microspheres by Spray Drying Process (스프레이 건조법을 이용한 PMMA/TiO2 다공성 입자 제조 및 특성 연구)

  • Paik, Dong-Hyun;Lee, Hyunsuk;Gang, Rae-Hyoung;Kim, Yong-Jin;Lee, John Hwan;Choi, Sung-Wook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.1
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    • pp.1-7
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    • 2016
  • Highly porous polymethyl methacrylate (PMMA) microspheres impregnated by $TiO_2$ powder were prepared by spray drying method. The particle size and the porosity were controlled by optimizing the co-solvent ratio and the polymer concentration. $TiO_2$ powder was impregnated into the microspheres upto 74.6 wt% content based on the weight of the resultant $PMMA/TiO_2$ microspheres. SEM images showed that $TiO_2$ powder was well distributed throughout the inside of the microsphere. EDX mapping showed that the Ti signal was well detected from every part of the microspheres, which was the evidence of the formation of the $PMMA/TiO_2$ composite. Hg porosimetry result showed that the porosity was found to be over 50% regardless of the $TiO_2$ contents. The final product was found to have high oil-absorbing capacity and great hiding power, both of which are key properties in designing the microsphere materials for make-up cosmetics application.