• Journal of Biomedical Engineering Research
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• 제19권5호
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• pp.539-546
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• 1998

The purpose of this study is to estimate human emotion quantitatively under colors and music stimuli and to examine the for correlation between color and music sensibility. Physiological signals(electroencephalogram, electrocardiogram, Galvanic skin conductivity and respiration rate) were measured to compare color with music sensibilities. The personality of the subject were investigated using factor analysis and semantic differential method of 20 items(7 interval scaled). The results showed that red, yellow and violets color provoked active and exciting senses mainly as dance, rock and blues music. While blue, cyan and pink colors ware involved in tranquil and resting emotions deeply as classic and ballade music.

• Transactions of the Korean Society of Mechanical Engineers B
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• 제39권11호
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• pp.897-903
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• 2015

In this paper, the contrast therapy of skin was numerically investigated by solving the conjugate heat transfer problem. A finite volume method based on the SIMPLE algorithm was adopted to solve the axisymmetric incompressible Navier-Stokes equations, coupled with an energy equation. These equations are strongly coupled with the Pennes bio-heat equation in order to consider the effect of blood perfusion rate. We investigated the thermal response of skin at some selected depths for various input temperature profiles of a stimulator for contrast therapy. From the numerical simulations, the regions with cold/hot threshold temperatures were found for five input temperature profiles. It was shown that the temperature varies mildly for different input profiles as the depth increases, owing to the Pennes effect. The input temperatures for effective hot/cold stimulation of dermis layer were found to be $47^{\circ}C$ and $7^{\circ}C$, respectively. The present numerical results will be used for finding an optimal temperature profile of a stimulator for contrast therapy.

• Journal of the Society of Cosmetic Scientists of Korea
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• 제43권4호
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• pp.281-287
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• 2017

Stress in skin plays a significant role in both the direct/indirect regulation of cellular processes occurring in hair, which in turn affect the hair cycle. However, experimental data regarding the effects of stress-related corticotropin releasing factor (CRF) released by stress on the apoptotic process involved in hair is limited. Therefore, we investigated the acceleration of early-stage apoptosis induced by atopy-related stress using a 2,4-dinitrochlorobenzene NC/Nga mice model. Expression of CRF, its related proteins, annexin V, and mitochondrial dysfunction were measured by immunohistochemical analyses. Atopic stress strongly stimulated stress hormones response, such as CRF and adrenocorticotropic hormone, in outer epithelial sheath of the hair. Moreover, its stress induced mitochondrial damage and early-stage apoptosis of cells in hair root. These findings suggest that hair damage due to apoptosis in atopy model is accelerated in a high CRF environment. Importantly, the effect of stress-related CRF on apoptosis processes involved in atopy dermatitis-related hair loss, suggests that the CRF-regulating development or maintenance materials may provide effective therapeutic strategies for hair health.

• 보건세계
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• 제53권7호통권599호
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• pp.35-39
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• 2006

결핵균이 몸 속에 들어와서 결핵균 특이T-림프구의 분화 및 증식을 자극하여 투베르클린 검사 양성을 보일 정도로 충분한 숫자의 결핵균 특이T-림프구들이 형성될 때 까지는 약 4주가 소요된다.

• Journal of Biomedical Engineering Research
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• 제23권1호
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• pp.73-79
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• 2002

The goals of this study are twofold: To investigate non-phobics'and Phobics'Physiological response in virtual environments. and to analyze the trend of phobics' Physiology during virtual reality treatment. As a measure of Physiology. heart rate, skin resistance. and skin temperature were acquired. The data of two group subjects were analyzed: twenty-two non-Phobic subjects (M=32.94 years). thirty-six subjects with fear of flying (M=40.12 yearn) who met the DSM-lV criteria for a fear of flying. As a result. skin resistance showed significant differences between non-Photics and phobics. T(56) =2.978, P〈0.01 And the physiological responses of 33 subjects among the Phobics. who succeed to fly without medicine after virtual reality treatment, showed a gradual trend toward the non-Phobics Physiological responses as therapy sessions went on. In this study. Physiological monitoring. skin resistance appeared to be useful both in understanding the Physiological state of Phobic individuals and in evaluating the results of treatment in virtual reality Psychotherapy.

• Science of Emotion and Sensibility
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• 제5권2호
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• pp.11-22
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• 2002

This study investigated the effects of mild mental imagery inducing pleasantness or unpleasantness and cognitive mental arithmetic task on skin conductance level. Subjects were f undergraduates(male 5, female 4). They were given the list of the words and asked to write down the liked objects and the disliked ones freely associated with these words. Among these objects the most-liked one and the most disliked one were selected as the self-induced mental imageries. Data-collection procedures were as follows ; first baseline, pleasant imagery, 2nd baseline, unpleasant imagery, finally 3rd baseline, and mental arithmetic task subtracting continuously 7 from the number 500. During these trials, the SCLs were recorded every 10 seconds. The results indicated that there were nonsignificant differences between the 3 trial-baselines ot each condition. This suggested that unlike the procedures used in the previous studies, our procedures would give the stability of the baseline level necessary for the comparison of the effects of several stimuli. Also, the level of skin conductance in mental arithmetic condition was significantly higher than that of the emotional mental imagery. This suggested the possibility that mental arithmetic task would gave rise to the higher physiological arousal in comparison to mental imageries. Overall, it was suggested that the procedures and the stimulus presentation methods used in this preliminary study could be useful for the data-collection techniques for The future study. Implications for the future study were presented.

• Science of Emotion and Sensibility
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• 제10권3호
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• pp.471-480
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• 2007

Negative emotions play an important function as to human's existence. In this research, we employed the audio-visual film clips to induce negative emotions and examined the classified responses in the autonomic nervous system(ANS) due to each negative emotion.30 adults(22.6 years $old{\pm}1.24$, 15 males and 15 females) took part in this experiment. Through the preliminary experiment, 2 minutes film's stimuli were selected as the emotion-induced stimuli. During the period when participants were viewing and listening to the selected movie, EDA and ECG were examined as soon as one stimulus was displayed, participants were tested by completing the psychological appraisals of their experienced emotion due to each emotional stimulus. With regard to the result of analyzing the psychological responses, each negative emotion appropriately and effectively induced its target emotion. While concerning the result of analyzing ANS responses, each negative emotion induced its respective activation in ANS. What is more, compared with other types of negative emotional stimuli, the scaring stimulus induced higher activation of the sympathetic nervour system(SNS) as to the indexes in EDh and ECG. This research made segmentation of ANS responses to each negative emotion, which has its significance.

• Journal of the Society of Cosmetic Scientists of Korea
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• 제35권4호
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• pp.277-285
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• 2009

Forsythia fructus has been shown to have antioxidative, anti-inflammatory, antiviral, antitumor, antibacterial, antipyretic and anti-aging activities. This work was carried out to investigate the anti-inflammatory effects of the Korean traditional medicinal prescriptions containing Forsythia viridissima extract. The prescriptions containing Forsythia fructus were evaluated for antioxidative effects, inhibitory effects on lipoxygenase activity and on LPS-induced NO and $PGE_2$ production. In human irritation test, they did not show any adverse effect. Based on these results, we suggest that the se prescriptions hold great promise for application as an anti-inflammatory agent for trouble skins such as atopic dermatitis and acne.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 한국어업기술학회 2000년도 추계수산관련학회 공동학술대회발표요지집
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• pp.187-188
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• 2000

최근 자외선 차단제의 사용이 증가하면서 자외선 차단제 도포로 인한 자극성 피부염, 접촉 피부염, 광알레르기성 또는 광독성 피부염 등의 보고가 증가하고 있어 피부에 자극이나 알레르기 반응, 독성을 나타내지 않는 적절한 천연소재 자외선 차단제의 개발에 대한 필요성이 증대되고 있다. 이에 본 연구에서는 새로운 자외선 차단제 개발을 위한 기초 자료를 확보하기 위하여, 국내산 해조류 중의 자외선 흡수 물질의 분포를 조사하였다. (중략)

• 월간산업보건
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• 통권273호
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• pp.40-43
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• 2011

Perchloromethyl mercaptan에 대한 직업적 노출기준으로 TLV-TWA 0.1 ppm(0.76 mg/$m^3$)으로 권고한다. TLV-TWA 0.1 ppm(0.76 mg/$m^3$) 은 눈과 코의 자극 그리고 불쾌한 냄새로 인한 불편함의 가능성을 최소화하는 수준이다. Perchloromethyl mercaptan에 대한 동물 노출 실험연구와 근로자들의 노출연구 자료는 매우 제한적이다. 사고로 확인되지 않은 농도에 근로자들이 노출된 경우, 발견된 증상과 징후는 눈, 목, 가슴에 심한 자극과 기침, 눈물, 호흡곤란, 메스꺼움, 구토, 빈맥, 청색증, 경련 그리고 폐부종에 의한 사망이다. Perchloromethyl mercaptan을 활용하는 생산설비에서 TLV-TWA 0.1 ppm 이하 농도의 증기에 노출되었을 때 질병을 유발하였다는 보고는 없었다. 피부흡수, 발암성 그리고 TLV-STEL을 권고하기 위한 유용한 자료는 충분하지 않다.