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Anti-inflammatory Effects of Prescription Extracts Containing Forsythia viridissima L.  

Kim, Mi-Jin (R&D Center, Saimdang Cosmetics Co., Ltd.)
Im, Kyung-Ran (R&D Center, Saimdang Cosmetics Co., Ltd.)
Yoon, Kyung-Sup (R&D Center, Saimdang Cosmetics Co., Ltd.)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.35, no.4, 2009 , pp. 277-285 More about this Journal
Abstract
Forsythia fructus has been shown to have antioxidative, anti-inflammatory, antiviral, antitumor, antibacterial, antipyretic and anti-aging activities. This work was carried out to investigate the anti-inflammatory effects of the Korean traditional medicinal prescriptions containing Forsythia viridissima extract. The prescriptions containing Forsythia fructus were evaluated for antioxidative effects, inhibitory effects on lipoxygenase activity and on LPS-induced NO and $PGE_2$ production. In human irritation test, they did not show any adverse effect. Based on these results, we suggest that the se prescriptions hold great promise for application as an anti-inflammatory agent for trouble skins such as atopic dermatitis and acne.
Keywords
prescription extracts containing Forsythia viridissima; anti-inflammatory effect; antioxidative effect; protaglandin $E_2$; nitric oxide;
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Times Cited By KSCI : 1  (Citation Analysis)
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