• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2021.11a
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• pp.44-45
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• 2021

황산화물, 미세먼지 등 대기환경의 오염원은 선박이 많은 비중을 차지하고 있다. 오늘날 인간은 해양을 삶의 영역을 넓히고 있다. 하지만 해양에서 대기환경을 측정할 수 있는 방법은 제한이 되어있다. 해양에는 선박의 안전항해를 도모할 다양한 종류의 항로표지가 설치되어 있다. 따라서 항로표지를 이용하여 해양의 대기환경을 측정하여 해양과 밀접한 관련이 있는 국민에게 서비스하고자 한다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2021.11a
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• pp.83-84
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• 2021

국내 교량등용 등명기의 최근 5년간 정기검사 현황을 통계화하였으며, 제조사별 색상별 광학특성을 조사·분석하여, 향후 교량등명기 성능 개선을 위한 기초자료로 활용하고자 한다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2023.11a
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• pp.30-32
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• 2023

전국 항만, 연안해역의 항로표지에 해양기상 및 조류신호표지를 구축하여 국지적 해양관측 정보를 실시간으로 서비스하고 있다. 이번 연구에서는 품질분석과 관계자간 간담회를 통해 얻은 현 문제점을 개선하기 위한 조치사항들을 통해 정상자료율을 높여 해양기상정보 서비스 품질을 개선하였다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2023.11a
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• pp.182-184
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• 2023

'스마트 항로표지 현장시설 고도화 연구'를 통해 다양한 센서를 통해 해상 데이터를 수집하고, 이를 가공하여 선박과 육상 연계시스템에 전파하는 방안이 논의되고 있다. 본 논문에서는 특정 업체에 종속되지 않고 미래 기술 발전에 유연한 대응이 가능하도록 스마트 항로표지 인터페이스 플랫폼에 대한 기술 요구사항의 표준화 방안을 정리한다. 이미 정의된 표준 구문은 그대로 수용하고, 신규 센서의 경우 관련 구문을 새로 정의하여 표준화하며 장치들을 직집 연결하거나 망 접속을 통해 연결하기 위해 정의되어야 하는 사안들을 정리한다.

• The Korean Journal of Nuclear Medicine Technology
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• v.22 no.1
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• pp.51-54
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• 2018

Purpose $^{18}F-THK5351$ is the newly developed PET probe for tau imaging in alzheimer's disease. The purpose of study was to establish the automated production of $^{18}F-THK5351$ on a commercial module. Materials and Methods Two different approaches were evaluated for the synthesis of $^{18}F-THK5351$. The first approach (method I) included the nucleophilic $^{18}F$-fluorination of the tosylate precursor, subsequently followed by pre-HPLC purification of crude reaction mixture with SPE cartridge. In the second approach (method II), the crude reaction mixture was directly introduced to a semi-preparative HPLC without SPE purification. The radiosynthesis of $^{18}F-THK5351$ was performed on a commercial GE $TRACERlab^{TM}$ $FX-_{FN}$ module. Quality control of $^{18}F-THK5351$ was carried out to meet the criteria guidelined in USP for PET radiopharmaceuticals. Results The overall radiochemical yield of method I was $23.8{\pm}1.9%$ (n=4) as the decay-corrected yield (end of synthesis, EOS) and the total synthesis time was $75{\pm}3min$. The radiochemical yield of method II was $31.9{\pm}6.7%$ (decay-corrected, n=10) and the total preparation time was $70{\pm}2min$. The radiochemical purity was>98%. Conclusion This study shows that method II provides higher radiochemical yield and shorter production time compared to the pre-SPE purification described in method I. The $^{18}F-THK5351$ synthesis by method II will be ideal for routine clinical application, considering short physical half-life of fluorine-18 ($t_{1/2}=110min$).

• The Korean Journal of Nuclear Medicine
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• v.32 no.6
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• pp.516-524
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• 1998

Purpose: Radiolabeled CEA79.4 antibody has a possibility to be used in radioimmunoscintigraphy or radioimmunotherapy of cancer. We investigated the in vitro properties and biodistribution of CEA79.4 antibody labeled with Re-188 or Tc-99m. Materials and Methods: CEA79.4 was reduced by 2-mercaptoethanol to produce-SH residue, and was labeled with Re-188 or Tc-99m. For direct labeling of Tc-99m, methylene-diphosphonate was used as transchelating agent. CEA79.4 in 50 mM Acetate Buffered Saline (ABS, pH 5.3) was labeled with Re-188, using stannous tartrate as reducing agent. In order to measure immunoreactivity and the affinity constant of radiolabeled antibody, cell binding assay and Scatchard analysis using human colon cancer cells SNU-C4, were performed. Biodistribution study of labeled CEA79.4 was carried out at 1, 14 and 24 hr in ICR mice. Results: Labeling efficiencies of Tc-99m and Re-188 labeled antibodies were $92.4{\pm}5.9%$ and $84.7{\pm}4.6%$, respectively, In vitro stability of Tc-99m-CEA79.4 in human serum was higher than Re-188-CEA79.4. Immunoreactivity and affinity constant of Tc-99m-CEA79.4 were 59.2% and $6.59{\times}10^9\;M^{-1}$, respectively, while those of Re-188-CEA79.4 were 41.6% and $4.2{\times}10^9\;M^{-1}$, respectively. After 24 hr of administrations of Re-188 and Tc-99m labeled antibody, the remaining antibodies in blood were 6.32 and 9.35% ID/g respectively. The biodistribution of each labeled antibody in other organs was similar because they did not accumulate in non-targeted organs. Conclusion: In vitro properties and biodistribution of Re-188-CEA79.4 were similar to those of Tc-99m-CEA79.4. It appears that Re-188-CEA79.4 can be used as a suitable agent for radioimmunotheraphy.

• Korean Security Journal
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• no.55
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• pp.31-55
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• 2018

The purpose of this study is to analyze the precedence analysis of traffic safety facilities installation for traffic accidents. The main results were as follows. First, the precedence of the number of traffic safety signs installation for the number of traffic accident is follows. The number of traffic safety signs[total number] (time precedent 1), the number of traffic safety signs[attention] (time precedent 7), the number of traffic safety signs[regulation] (time precedent 7), the number of traffic safety signs[indication] (time precedent 4) precede the number of traffic accidents as negative(-) relationship. Second, the number of traffic signal equipments[pedestrian lamp] (time precedent 2) precedes the number of traffic accidents as negative(-) relationship. Third, the precedence of the increase/decrease rate of traffic safety facilities installation for the increase/decrease rate of traffic accident is follows. The increase/decrease rate of traffic safety signs[total number] (time precedent 1), the increase/decrease rate of traffic safety signs[attention] (time precedent 1), the increase/decrease rate of traffic safety signs[indication] (time precedent 1), the increase/decrease rate of traffic safety signs[auxiliary] (time precedent 1) precede the increase/decrease rate of traffic accidents as negative(-) relationship. Fourth, the increase/decrease rate of traffic signal equipments[pedestrian lamp] (time precedent 0) accompanies the increase/decrease rate of traffic accidents as positive (+) relationship.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.13 no.4
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• pp.38-47
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• 2014

Ministry of Land, Infrastructure and Transport (MOLIT) Affairs of Korean government improved RSMS to be linked with GIS data and now we have research foundation. In case of expressway and rural national highway, there is a referenced place-name for direction road sign, but there is no reference in urban road and is only a guideline. Direction signs in urban could not have consistent place-name and it is vary difficult to select the proper place-name. Based on the change of analysis environment and perception of road sign - related problem, This study is aimed to suggest how to deduce the spatial impact zone of place-name from DB and GIS in RSMS of Changwon City. The results indicated that there is a spatial difference between place-names according to whether is near or far on the road sign. It is expected that this method would be effectively used in case of new road sign and so the process to select the place-name would be simple.

• Journal of Navigation and Port Research
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• v.43 no.3
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• pp.166-171
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• 2019

Aids to Navigation(AtoN) Accident can reduce the credibility of AtoN by adding extra works to the administrators, and cause burdens and inconveniences to the users during their navigation leading to social costs (or economic losses). Prior research on social cost estimation model to determine the Encounter cost, Administrative cost and Risk cost on the Aton model was done to estimate the economic losses due to AtoN Accident. However, this research could not provide adequate study results on risk cost estimates. Therefore, this study complements the estimation model presented in the previous study, and the estimated social cost of 249 AtoN Accidents that occurred during the last 10 years (2008-2017) in the Busan Regional Office of Oceans and Fisheries jurisdiction area. The risk cost was estimated using contingent valuation method since the AtoN is a non-market goods. As a result, the social cost of AtoN Accidents for the past 10 years was estimated to total 12.4 billion won including Encounter cost of 3.1 billion won (25.38%), Administrative cost of 1.7 billion won (13.62%), and Risk cost of 7.5 billion won (61.01%).

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2010.04a
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• pp.143-144
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• 2010

Recently, IALA has introduced AIS AtoN and standardized Aids to Navigation communication system and the World-wide IALA-Net has announced plans to build the system. Systematic beacon network may offer opportunities to make infrastructure for information service and upgrade AtoN service performance. This paper proposes Aids to Navigation information service network for e-NAV. Network based on AIS is consist of AIS AtoN channels as Real, Synthetic or Virtual AIS AtoN. And inner network is consist of Wireless networks as AIS, WCDMA, WIFI, WlBRO, USN or VSAT. Introducing of various network systems can lead to combine and design among land, beacon and service network infrastructures.