• Title/Summary/Keyword: 표지자

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작업 안전성 강화를 위한 자기규율 예방체계 구축

  • 하덕인
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2023.11a
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    • pp.16-17
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    • 2023
  • 항로표지 분야의 중대재해 사고 예방을 위해 항로표지선, 부표정비선에 적용할 수 있는 사례를 찾아 도입하고 나아가 작업자 스스로 작업환경 내 안전을 지킬 수 있도록 안전의식 고취와 함께 자기규율 예방체계를 구축하고자 함

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Quality Control of Radiopharmaceutical (진단용 방사성 의약품의 정도관리)

  • An, Sung-Min;Hong, Tae-Kee;Ham, Jun-Cheol;Kim, Sung-Chul
    • The Journal of the Korea Contents Association
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    • v.9 no.11
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    • pp.240-246
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    • 2009
  • Quality control test in this field of study were carried out in 3 categories, radionuclidic purity, chemical purity and radiochemical purity. Also, indication efficiency was tested every 3 hours changed after binding the radiopharmaceutical to see how long the medicine is available for usage after indicating. The result showed that currently used radiopharmaceutical have good radionuclidic purity and chemical purity. However, radiochemical purity indication showed small differences depending on indication method and indication period. Radiopharmaceutical are indicated by treatment providers, so they need to pay more attention to the indication process and quality control to provide more efficient treatment.

Implementation Plan of Aids to Navigation Status Statistics Service (항로표지 현황통계 서비스의 구현 방안)

  • Beom-Sik Moon;Tae-Goun Kim;Yun-Ja Yoo;Cjae-Uk Song;Jeong-Gu Kang
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2023.05a
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    • pp.286-287
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    • 2023
  • The function of Aids to Navigation(AtoN) must be sustainable. In order to provide sustainable services, it is necessary to prevent repeated AtoN accidents through accurate data analysis and to perform maintenance to maintain functions. What is needed for this is the AtoN status statistics service. AtoN Status Statistics Service is a service that extracts existing data in gml format and extracts and processes it in the period, type, and format desired by the manager.

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Surface Marker Analysis in Acute Leukemias (백혈병의 면역학적 표지자검사의 결과분석)

  • Moon, Jin-Young;Lee, Chae-Hoon;Kim, Kyung-Dong;Kim, Chung-Sook
    • Journal of Yeungnam Medical Science
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    • v.14 no.2
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    • pp.359-369
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    • 1997
  • We studied the expression of the cell surface antigen associated with myeloid and lymphoid leukemias on bone marrow or peripheral blood blast cells from 153 leukemic patients including 61 cases of acute myelogenous leukemias(AML), 46 of acute lymphocytic leukemias(ALL) and 12 of acute leukemias. They were analyzed by direct or indirect immunofluorescence method for reactivity with the monoclonal antibodies to B cells(CD10, CD19, SmIg), T cells(CD2, CD5, CD7, CD3, CD4, CD8), myeloid antigen(CD13, CD14, CD33, CD61) and a nonspecific antigen, HLA-DR. Lymphoid associated markers detected on AML is CD7 32.8%, CD10 14.8%, CD5 13.1%, CD2 6.6% and CD19 1.6%. TdT was positive in 4.9% of AMLs. Hybrid leukemias were 8 cases out 61 AML cases and were mainly composed of monocytic lineage, M4 and M5a. Myeloid markers detected in ALL were CD13 2.2% and CD33 2.2%. In this study, immunologically classified ALLs were composed of 65.2% of CALLA (+) B precursor type, 10.9% of CALLA (-) B precursor pattern, 8.7% of T cell type, 2.2% of B cell type, 4.5% of mixed lymphoid lineage(B&T), 2.2% of undifferentiated leukemia, and 6.5% of hybrid leukemia. Twelve cases of acute leukemias ware finally diagnosed to be 5 cases of hybrid leukemia, 3 cases of B lineage, 3 case of T lineage and 1 case of mixed lymphoid(B&T) leukemia. In summary, we think the best method for typing acute leukemias is by using a combination of FAB classification and immunophenotying.

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Thrombin Detection with Tetrabromophenolphthalein Ethyl Ester Adsorbed on Aptamer-attached Conductive Polymer (전기전도성 고분자 위에 고정된 압타머에 흡착된 테트라브롬페놀프탈레인 에틸 에스테르를 이용한 트롬빈 검출)

  • Chung, Saeromi;Noh, Hui-Bog;Shim, Yoon-Bo
    • Journal of the Korean Electrochemical Society
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    • v.19 no.4
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    • pp.134-140
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    • 2016
  • An aptamer-based biosensor using a new redox indicator has been examined for the electrochemical detection of thrombin. The aptamer modified primary aliphatic amine was covalently immobilized onto poly-(5,2':5',2"-terthiophene-3'-carboxylic acid) (polyTTCA) layer. Tetrabromophenolphthalein ethyl ester (KTBPE) was interacted to aptamer and used as an electrochemical indicator. Prior to the detection, the oxidation reaction of KTBPE onto aptamer modified layer was also investigated using differential pulse voltammetry. The characterization of the final sensor (KTBPE/aptamer -polyTTCA) was performed by voltammetry, QCM, and ESCA. After binding of thrombin onto KTBPE/aptamer based sensor, the peak signal of KTBPE was gradually decreased. The sensor exhibited a dynamic range between 10.0 and 100.0 nM with the detection limit of $1.0{\pm}0.2nM$.

Relationship between the Expression of VEGF, HIF-$1{\alpha}$ and Stage in Non-Small Cell Lung Carcinoma (비소세포성 폐암에서 VEGF, HIF-$1{\alpha}$의 발현과 병기의 상관성)

  • Song, Ho-Seung;Kim, Chul-Woung;Lee, Moo-Sik;Na, Bak-Ju;Lim, Nam-Gu
    • Proceedings of the KAIS Fall Conference
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    • 2009.05a
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    • pp.227-230
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    • 2009
  • 목적 : 비소세포 폐암에서 HIF-$1{\alpha}$, VEGF의 발현과 예후와 관련된 여러 임상적 표지자 및 병리학적 표지자와의 상관관계를 조사하고자 하였다. 방법 : 이들의 예후인자로서의 의미를 알아보고자 외과적으로 절제한 44예의 비소세포 폐암종을 대상으로 VEGF, HIF-$1{\alpha}$에 대한 면역조직화학염색을 시행하였다. 결과 : WHO 분류에 의한 조직학적인 형태인 편평세포암종 28예, 선암종 16예의 비세포성 폐암이 이 연구에 포함되었다. 비소세포성 폐암 24예와 16예에서 VEGF 및 HIF-$1\alpha$이 발현되었다. 결론 : 이 연구에서 VEGF 발현과 병기와의 상관관계, HIF-$1{\alpha}$의 과발현과 병기 사이에서 통계적으로 유의한 상관관계를 볼 수 없었다. 또한 HIF-$1{\alpha}$의 과발현과 VEGF의 발현 사이에 통계학적으로 유의한 관련성이 없었다.

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DNA칩을 이용한 위암의 진단 및 예후 측정

  • Eom Won-Seok
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2006.02a
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    • pp.11-18
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    • 2006
  • 바이오칩의 대표 주자인 DNA 칩은 점차 분자생물학의 주요 도구로 인식되고 있다. 쓰임새 또한 다양해져 기초 생물학, 기능 유전체학 연구뿐만 아니라 임상 현장에서의 적용을 위한 연구가 활발히 진행되고 있다. 임상분야에서 최근 주목 받고 있는 분야가 DNA 칩을. 이용한 질병진단 및 예후 측정이다. 개별 환자 세포의 분자유전학적 상태는 DNA 칩의 유전체 프로파일링(genome-wide profiling)으로 상세히 파악될 수 있으므로, DNA 칩은 질병의 세부아형 진단, 약물에 대한 개인 민감도 측정, 정확한 예후 측정을 통한 환자의 세심한 관리 등 미래 의료의 핵심이라 할 수 있는 개인별 맞춤 치료(personalized medicare)를 가능하게 하는데 지대한 역할을 할 것으로 기대되고 있다. 특히 수많은 질병 중에서 현대인의 난치병으로 손꼽히는 암은 DNA 칩 분석의 주요 적용 대상이다. 암에 연관된 복잡한 메커니즘을 기존의 단일 표지자로 진단하는 데는 한계가 있기 때문에, DNA 칩을 이용해 질병의 특정 phenotype과 관련 있는 암의 특이 패턴을 전사체 수준에서 분석하여 새로운 형태의 분자유전학적 표지자(transcriptional molecular signature)를 발굴하는 것이다 본 발표에서는 이러한 연구에 쓰이는 DNA 칩 분석 방법들과 실제 위암 데이터에 적용한 사례에 대해 논의하고자 한다. 연세의대 암전이 연구센터의 17K cDNA 칩을 이용하였으며, 진단 및 예후 측정을 위한 여러 분석 방법을 수행하였다.

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Sexual Image of the Cover Models in Men's Magazine (남성 잡지 표지 모델의 섹슈얼 이미지)

  • Yun, Eul-Yo
    • The Journal of the Korea Contents Association
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    • v.10 no.6
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    • pp.275-285
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    • 2010
  • As we enter an era of emotional and endlessly competitive society, there has been a lot of changes happening to the styles and images of men, traditionally associated with strength and power. Today, the media is giving information on today's trendy men's styles and images to meet the growing demand by consumers, and giving appropriate gains in the process to all - both information providers and consumers. Generally speaking, the cover of a magazine represents the concept and image of the magazine. The cover model is closely tied with the symbolic image of the magazine, the current times, and what the general public wants. Therefore, research on the cover models of a lifestyle magazine has significance in that the current style trends will be able to be understood directly. The present research investigated the sexual images of men's magazine cover models. In carrying out the research, the sexual images were classified into the following: homosexual, cross sexual, metro sexual, and uber sexual. The research findings showed that uber sexual is the dominant sexual image in men's magazines in Korea, followed by metro sexual. In conclusion, the findings suggest an expansion of the traditional image of men, happening with the changes in traditional sex roles.