• Journal of the Korean Society of Food Science and Nutrition
• /
• v.37 no.1
• /
• pp.16-19
• /
• 2008

Bone mass in adults decreases with age because of the imbalance between the rate of bone formation and resorption. We performed this study to investigate whether Asparagus cochinchinensis (Lour.) Merr. (ACAE) plays a role in osteoblasts differentiation and osteoclasts formation. Ethanol extract of ACAE showed increase in the differentiation and alkaline phosphatase activity of osteoblasts. Also, it decreased the number of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells (OCLs) and TRAP activity. Therefore, ACAE has the potential to prevent bone-related diseases such as osteoporosis by increasing the differentiation of osteoblasts and reducing both the number and activity of osteoclasts.

• Journal of Embryo Transfer
• /
• v.12 no.3
• /
• pp.253-258
• /
• 1997

토끼에서는 수정란 이식과 같은 기본적인 번식공학적 방법의 효율성이 아직 생쥐와 같은 실험동물에 비해 떨어지고 있어 생물공학적인 기술을 응용하는데 큰 어려움이 있다. 특히 유전자 이식에 의한 형질전환 토끼의 생산과 같은 생물공학적인 기술을 실용화하는데 효율이 높은 수정란이식 기술의 개발이 필수적이라고 할 수 있다. 본 연구에서는 토끼에서 수정란 이식 기술의 첫 단계인 과배란 유도를 효율적으로 이용할 수 있는 방법을 정립하기 위해 반복적인 과배란 유도가 배란율 및 수정란의 질적인 면과 양적인 면에 미치는 영향을 조사하였다. 연구방법으로는 FSH와 HCG를 사용하여 과배란을 유도하였고 2.5 개월의 반복처리간격으로 3번의 반복적인 과배란 처리를 한 후 반복처리에 따른 배란율과 배란된 난자의 형태학적 상태, 배양에 의한 발생 능력 상태 등을 감소하였으며 배란수의 변이도 커지는 경향을 나타내었다(첫번째, 32.6(+-)2.5; 두번째 28.7(+-)3.7; 세번째 20.99(+-)3.8). 제 2극체의 돌출, 전핵의 형성, cummulus cell의 존재등에 의한 회수된 난자의 형태학적 관찰에 의한 방법으로 난자를 분류한 결과 과배란의 반복수가 증가함에 따라 다양한 모양의 난자가 회수되어 배란이 광범위한 시간대에 일어나고 있음을 나타내었다. 또한 과배란의 반복적인 유도에 의해 난소의 혈포수는 증가하였으나 채란된 난자의 채외배양에 의한 발육율에는 차이가 없었다. 그러므로 과배란의 반복적인 유도는 공란토의 난소반응에는 영향을 미쳤으나 난자의 질에는 영향을 미치지 않았음을 나타낸다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2019.05a
• /
• pp.306-309
• /
• 2019

The damage to farms due to wild animals such as wild boars and elks increases every year, but, in the current system, the catchers from government hunt animals by using guns at night as making an effort to detect wild animals personally by using flashlights. This is very time-inefficient and immediate follow-up action on being damaged is not possible. In this paper, we introduce a system which can detect and recognize the wild animals or the people with high accuracy using thermal imaging camera and infrared camera in company with deep learning technology, so that could kick out or catch the wild animals more quickly than current system.

• Clinical and Experimental Reproductive Medicine
• /
• v.24 no.1
• /
• pp.13-20
• /
• 1997

The objective of this study was to determine the effect of EGF on the preimplantation development of mouse IVF embryos and their ICM and TE cell number. And also, we examined the expression of EGF-R protein on embryonic development by indirect immunofluorescence. The results obtained in these experiments were summarized as follows; Group culture (5 embryos/ 25 ${\mu}l$) showed more improved development rate to blastocyst than singly culture. This inferior development of singly cultured 2-cell embryos improved by the addition of EGF. Especially, 2-cell embryos cultured singly in 10 ng/ml of EGF (62.4%) indicated significant difference in development to blastocyst compared with control group (47.9%). Also, cell number of ICM and TE by differential labelling showed the increased pattern in the EGF treatment group. The stimulating effect of EGF with the development level was significantly increased after 4-cell stage (p<0.05). ICM proportion also showed the increased pattern with the developmental level in the EGF treatment group. In addition, expression of EGF-R by indirect immunofluorescence detected after 4-cell stage. Therefore, EGF could stimulate preimplantation mouse embryo development by binding with expressed EGE-R after 4-cell stage and produce the more increased ICM and TE cell number of blastocyst.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2020.06a
• /
• pp.110-110
• /
• 2020

최근 낙동강유역에서는 여름철 폭염 및 가뭄의 영향으로 조류대경보가 발령되고 있으며, 급격한 수질환경적 변화가 이루어지고 있다. 본 연구대상유역인 낙동강에서도 가뭄으로 인해 녹조가 발생하여 조류경보가 발령되었다. 남조류의 대발생은 대량 번성 및 사멸에 따라 수체 내 산소 고갈 및 유기물 증가와 같은 문제를 야기하고 있다. 또한 남조류가 분비하는 독성물질 또한 수생태계와 인체에 유해하다. 그리고 인체에는 무해하다고 밝혀졌지만 수돗물 등에서 흙냄새와 같은 좋지 않은 냄새를 유발하는 냄새물인 지오스민, 2-MIB을 분비하여 정수공급체계의 악영향을 미친다. 본 연구대상 지점인 낙동강은 다기능 보 건설로 인해 하천 수심이 증가하고 유속이 느려지면서 정체성 수역 특성을 나타내고 있다. 이는 호소성 수역 특성을 나타내고 있음과 동시에 녹조발생과 같은 수질환경적 변화가 이루어지고 있다는 것을 의미한다. 본 연구에서 시각화 분석을 통해 낙동강 하류 남조류 발생현황을 분석하였으며, 랜덤포레스트를 이용하여 지점별 남조류 발생 주요 영향인자를 도출하였다. 조류경보제 발생 등급은 발령기준으로 관심, 위험, 대발생으로 구분된다. 학습데이터로 관심단계 기준인 남조류세포수 1,000 cell/mL 보다 작게 측정된 데이터들은 관심미만의 데이터로 Normal 등급으로 구분하였다. 구분된 발생등급을 범주형 변수로 설정하여 학습 데이터를 통해 모형을 구축하고 검증 데이터를 이용하여 모형 정확성을 평가하였다. 본 연구를 통해 조류발생 주요 영향인자를 도출하고 변수별 중요도를 평가를 통해 지점별 녹조 발생특성을 비교 분석하였다.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.30 no.11 s.158
• /
• pp.1495-1506
• /
• 2006

The purposes of this study are to investigate the formation and the change of apparel retail structure historically with the viewpoint that the retail structure is affected by the process of economic development. This study was done by literature research method and the result of this study is the following. The tailor and seamstress shops, the first clothing shops in Korea, were replaced by ready-made shops, because mass production system which had developed with the industrialization of Korea increased the advantage of economy of scale compared to handicrafts individual one. After that, the production system of apparel industry had been efficient continuously, while retail system had not. The retailing of famous brand apparel conducted by exclusive franchise store caused supplier oriented markets where the opinion and the desire of consumers were not reflected. While the retailing of the unknown brand apparel handled by small retail stores were inefficient. As the apparel industry matured in 1990s, various types of new stores appeared such as specialty stores, discount stores, TV home shopping, internet shopping, outlet malls, and big fashion stores in Dongdeamoon. These new stores have features of seeking profits in mass merchandising. As these large retail stores grow, the apparel retail structure of Korea is changing from a fragmented market to a vertically integrated one. This change is shown by the decrease of stores per inhabitants. With the change of environment, the apparel retail system which has lagged behind comparatively is expected to develop into more efficient system based on the large capital investment which raise the advantage of economy of scale.

• Korean Journal of Clinical Pharmacy
• /
• v.10 no.1
• /
• pp.1-6
• /
• 2000

백내장 수술 추 염증치료를 위해 일반적으로 부작용이 많은 국소 점안 스테로이드를 사용해왔다. 최근 NSAID계열의 점안액이 항염증 치료약물로 개발되면서 선택적인 약물치료가 가능하게 되었으나 단일치료약물로 사용하는 경우는 드물다. 본 연구는 NSAID계 diclofenac 점안액의 백내장 수술 후 염증치료 효과를 스테로이드체 dexamethasone 점안액과 비교하여 단일 치료약물로서 사용할 수 있는 지 연구하고자하였다. 백내장 수술을 받은 환자로서 안압이 22 mmHg 이상 당뇨환자, 수술대상 눈에 이미 질환 및 수술 경력이 있는 자를 제외하였다. 백내장 수술 후 항염종 약물로서 diclofenac 또는 dexamethasone을 28일 동안 투여하고 항염증효과의 평가를 위하여 세극등 검사로저 전방내 염증세포와 결막, 각막등의 전안부 관찰을 수술 전, 수술 후 1, 3, 7, 14, 28일에 시행하였고, 시력검사는 수술 추 7, 28일에 시행하였다. 안전성의 평가는 안압검사와 세극등 검사상 관찰된 이상소견으로 평가하였다. 총 73명의 연구대상 중 dexameasone군은 41명, diclofenac군은 32명이며 두 군간에 나이, 백내장의 심한 정도, 안구질환 등에 있어 유의한 차이가 없었다 전방내 항염증세포수의 감소에서 두 군간에 유의할 만한 차이가 없었고, 수술 후 최대 교정 시력에서도 동일한 효과를 보였다. 안전성에서 안압의 상승이 두군간에 통계적인 유의한 차이를 보이지 않았으나 dexamethasone군에서 1명의 환자가 45 mmHg 이상 증가하여 약물치료가 필요하였으나 diclofenac군에서는 안압이 상승한 환자가 없었다. 결론적으로 효능 및 안전성에서 두 약물간에 통제적, 임상적으로 유의한 차이가 없었으며 diclofenac 점안액은 백내장 수술 후 항염증치료제로서 충분한 효과가 있으며 안압상승, 감염 등 부작용이 우려되는 dexamethasone점안액의 대체약물로 사용될 수 있을 것으로 평가된다.

• Journal of Embryo Transfer
• /
• v.19 no.3
• /
• pp.229-237
• /
• 2004

The main objective of this study was to examine the effects of serum and gonadotropins supplement during in vitro maturation(IVM) of bovine oocytes on nuclear maturation and embryo development, and we also examine the cell number. 1 . The first polar body(PB) extrusion rates of Korean native cow(KNC) oocytes matured in medium with FBS or gonadotropins were similar among treatment groups. The development rate to the blastocyst stage was significantly higher in the group of both supplement FBS and gonadotropins(26.0％) than in the group of non-supplement(9.9％) and gonadotropins (12.0％). The numbers of inner cell mass (ICM) and trophectoderm (TE) cells and total cell numbers of blastocysts were highest in the group of both supplement FBS and gonadotropins, and the number of ICM cells was increased by FBS supplementation (p<0.05). 2. The PB extrusion rates of KNC oocytes matured in medium with FBS in the different duration of IVM was significantly higher in the 0-18hr(63.1％) and in the 9-18hr(63.4％) group than in the 0-9hr.(37.4％) group (p<0.05). The embryo development rates did not differ among treatment groups. The numbers of TE cells and total cell numbers of blastocysts were similar among treatment groups, but the number of ICM cells of the 0-18h. group were significantly higher than the other treatment groups (p<0.05). The results indicate that although TCM199 alone can support bovine oocyte maturation and development to the blastocyst stage, a high quality of blastocysts can be produced from oocytes matured in medium containing serum and gonadotropins.

• Resources Recycling
• /
• v.9 no.6
• /
• pp.36-44
• /
• 2000

Fly ash was composed of the unburned carbon and mineral particles. The former was able to attach on the bubbles, while the latter was not. Therefore, it was possible to separate the unburned carbon and the mineral from fly ash using the froth flotation process. This study was carried out to evaluate the separation efficiency as a function of the ny ash particle properties in the column flotation. Separation efficiency was analyzed for various size fraction of -38 fm,38~125 fm and 1125 W, and for various fly ash samples containing 7, 11, and 20 wt% unburned carbon. For the size fractions of -38 fm containing 7 wt% unburned carbon, separation efficiency was 86ft, whereas separation efficiency was found to be 74% for the size fraction of +125$\mu\textrm{m}$ containing 20 wt% unburned carbon. The results indicated that separation efficiency increased with the decrease in the particle size and the unburned carbon content of the fly ash.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.28 no.3
• /
• pp.328-333
• /
• 1983

Due to fast industrialization and reduced agricultural population, there has been increased farm mechanization to reduce the labor requirement. In rice production, mechanical transplanting has been increasingly popular due to the heavy labor requirement in hand transplanting and development of convenient transplanters. For mechanical transplanting, rice seedlings is grown in boxes with limited soils under super dense population, thus short period of exposure to unfavorable temperature and poor water management would cause severe damage to rice seedlings such as seedling damping off and the similar physiological disorders. Several chemicals were evaluated for their effectiveness to control the disease and disorders, and other effects as plant growth stimulants. 3-hydroxy-5-methylisoxazole-a soil fungicide, Metalozyl-a fungicide which controls mildew, SF 8002-the composite of above two chemicals, and Isoprothiolane-a fungicide which controls rice blast were found to be effective controling seedling damping off and similar physiological disorders, and improvement of physiological characteristics of the seedlings such as the amount of bleeding sap, rooting ability, negative geotrophism, and regrowth after cutting. The results indicated that the chemicals will be very effective raising healthy seedlings even under unfavorable environments by the improvement of physiological activities of seedlings and preventing seedling damping off and the similar physiological disorders.